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The map label for this gene is mmsR [H]

Identifier: 50084738

GI number: 50084738

Start: 1567494

End: 1568339

Strand: Direct

Name: mmsR [H]

Synonym: ACIAD1576

Alternate gene names: 50084738

Gene position: 1567494-1568339 (Clockwise)

Preceding gene: 50084737

Following gene: 50084739

Centisome position: 43.56

GC content: 42.08

Gene sequence:

>846_bases
ATGCAAGGATTAGCACTTCGTAACGAAGATGTCGTGAGTCAAACTTTGGGTTGTCGCCCAGAAGTGAGTTATGTCAACAA
ACAAAGTGACTGGCAAATGATGCGTTGGCGTCAGTTCGTGGGTCATTATAATTTAGACGCATTGCCCGAGCCAATGCTGG
TTGCTCATATTGGTGGTAAACAGCAGGTACATATGCGTGACGGTCAATGTTGGAGTCATACAGGCTCTAAACCTAGTGAC
ATGACCAATATGCCTGCACATGTTGCTTCTGGCTGGCTAGTGAATGGTGAATTAGATGTTGTCACCCTGACCTTACCACG
CGCAATCCGAGATTTCGTTACAGACGTCCGTTTTGCATACAGAGATACTTTAGGTATTGCGTTAATTAGACAAATGCTGG
CTAGTTTGTATGAACCACAAAGTGTAGAACGGGATCAATATATTGATTTACTGATGACCACTTTTGTCGCACATTTAAAT
CGTGCTGATACCCAACTGACGGATCAAATTCCAATAACAAGTTGTTCTGCGCATAGATTGCATCATATTTTAAATATGAT
CCGTGAACATCCTGAGCAAGAGTTTAGTTTGGATATCCTTGCAAGTGAAATCGACTTAACGCCTGCCCATTTTTGTCGTA
TGTTTCGTGAGGCAACAGGGATTACTCCTCACCAATATATCTTGAAATGCCGTTTACAGCGGGCAGAGCATTTGTTGAAT
AATTCCGATCTATCTATTTCCATGGTGGCTGAGGCGTCAGGATTTAATTCACAATCACATTTTACCCGATTGTTTTTAAA
AAAAATGGGGAAAAATCCGTCAGACTTAAGGCGACGACTGCATTAG

Upstream 100 bases:

>100_bases
CGTTTCGAATTAAAATCTGAACCAAGACGCTTTCGTTCTAATTTTTTAAATGGATTAAAGAATCTCAATGTGGTGCTTGT
CGCCAAATGAGGAGATCATC

Downstream 100 bases:

>100_bases
GAAATGAATAATACAAGGTCAATCACGAGATACTAAACGACATGCTTTAGCCTTTAGTTTGACCTCTAATATTAATTTTA
TACACGAATTTTTAAAGGTT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MQGLALRNEDVVSQTLGCRPEVSYVNKQSDWQMMRWRQFVGHYNLDALPEPMLVAHIGGKQQVHMRDGQCWSHTGSKPSD
MTNMPAHVASGWLVNGELDVVTLTLPRAIRDFVTDVRFAYRDTLGIALIRQMLASLYEPQSVERDQYIDLLMTTFVAHLN
RADTQLTDQIPITSCSAHRLHHILNMIREHPEQEFSLDILASEIDLTPAHFCRMFREATGITPHQYILKCRLQRAEHLLN
NSDLSISMVAEASGFNSQSHFTRLFLKKMGKNPSDLRRRLH

Sequences:

>Translated_281_residues
MQGLALRNEDVVSQTLGCRPEVSYVNKQSDWQMMRWRQFVGHYNLDALPEPMLVAHIGGKQQVHMRDGQCWSHTGSKPSD
MTNMPAHVASGWLVNGELDVVTLTLPRAIRDFVTDVRFAYRDTLGIALIRQMLASLYEPQSVERDQYIDLLMTTFVAHLN
RADTQLTDQIPITSCSAHRLHHILNMIREHPEQEFSLDILASEIDLTPAHFCRMFREATGITPHQYILKCRLQRAEHLLN
NSDLSISMVAEASGFNSQSHFTRLFLKKMGKNPSDLRRRLH
>Mature_281_residues
MQGLALRNEDVVSQTLGCRPEVSYVNKQSDWQMMRWRQFVGHYNLDALPEPMLVAHIGGKQQVHMRDGQCWSHTGSKPSD
MTNMPAHVASGWLVNGELDVVTLTLPRAIRDFVTDVRFAYRDTLGIALIRQMLASLYEPQSVERDQYIDLLMTTFVAHLN
RADTQLTDQIPITSCSAHRLHHILNMIREHPEQEFSLDILASEIDLTPAHFCRMFREATGITPHQYILKCRLQRAEHLLN
NSDLSISMVAEASGFNSQSHFTRLFLKKMGKNPSDLRRRLH

Specific function: Regulatory protein for the mmsAB operon. Activates the transcription of the mmsAB genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790339, Length=103, Percent_Identity=33.0097087378641, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786496, Length=102, Percent_Identity=30.3921568627451, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI171474011, Length=158, Percent_Identity=28.4810126582279, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 32231; Mature: 32231

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLALRNEDVVSQTLGCRPEVSYVNKQSDWQMMRWRQFVGHYNLDALPEPMLVAHIGGK
CCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
QQVHMRDGQCWSHTGSKPSDMTNMPAHVASGWLVNGELDVVTLTLPRAIRDFVTDVRFAY
CEEEECCCCEECCCCCCCCCCCCCCHHHHCCEEECCCEEEEEEEHHHHHHHHHHHHHHHH
RDTLGIALIRQMLASLYEPQSVERDQYIDLLMTTFVAHLNRADTQLTDQIPITSCSAHRL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
HHILNMIREHPEQEFSLDILASEIDLTPAHFCRMFREATGITPHQYILKCRLQRAEHLLN
HHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
NSDLSISMVAEASGFNSQSHFTRLFLKKMGKNPSDLRRRLH
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MQGLALRNEDVVSQTLGCRPEVSYVNKQSDWQMMRWRQFVGHYNLDALPEPMLVAHIGGK
CCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
QQVHMRDGQCWSHTGSKPSDMTNMPAHVASGWLVNGELDVVTLTLPRAIRDFVTDVRFAY
CEEEECCCCEECCCCCCCCCCCCCCHHHHCCEEECCCEEEEEEEHHHHHHHHHHHHHHHH
RDTLGIALIRQMLASLYEPQSVERDQYIDLLMTTFVAHLNRADTQLTDQIPITSCSAHRL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
HHILNMIREHPEQEFSLDILASEIDLTPAHFCRMFREATGITPHQYILKCRLQRAEHLLN
HHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
NSDLSISMVAEASGFNSQSHFTRLFLKKMGKNPSDLRRRLH
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339433; 10984043 [H]