BacMap

Definition	Acinetobacter sp. ADP1 chromosome, complete genome.
Accession	NC_005966
Length	3,598,621

Click here to switch to the map view.

The map label for this gene is caiD [H]

Identifier: 50084733

GI number: 50084733

Start: 1562518

End: 1563300

Strand: Direct

Name: caiD [H]

Synonym: ACIAD1571

Alternate gene names: 50084733

Gene position: 1562518-1563300 (Clockwise)

Preceding gene: 50084732

Following gene: 50084734

Centisome position: 43.42

GC content: 45.21

Gene sequence:

>783_bases
GTGGCAATGGAATACCACTTTATTCAGGTTGAAAAACAGCAACATTTAACAATTATTACTCTCAATCGTCCTGCAAGTTT
TAATGCATTAAATGCATCTGCCCATGAGGAGTTGGCTCAAGCTTTTGATCAATTTCAAAATGATGATGAGCAATGGGTTG
CGATTGTGACGGGTGTAGGGGAAAAAGCGTTTTGTGCAGGTCATGATTTAAAACAACAAGCAGCAGGTGGTGGTCTGGTG
ACACCGCAATCAGGTTTTGCAGGTTTAACAGCACGTTTCGATTTAACTAAACCTGTCATTGCTGCTGTAAATGGCGTCGC
AATGGGTGGTGGGTTTGAGCTGGCTTTAGCTTGCGACTTAATTATTGCATCTGAAAATGCTGTTTTTGCCTTGCCTGAGC
CAAGAGTCGGTTTGGCTGCCTTGGCAGGTGGAATGCAACGTTTACCTCAAGTCATTGGGTTAAAAAGAAGTATGGGAATG
TTGCTTACGGGACGTCGGGTATCGGCACAAGAAGGATTCGAGCTGGGTTTTGTCAATGAAGTAACCAGTGGACCCGTACT
CGAAGCAGCGAAGAGATGGGCAAATGAAATCTTGGCATGTAGTCCGCTATCGATACGTGCTACCAAACAGACCGTGTTAA
GAGGGTTGGAGAGTTCGGTTGAACAAGCCATGCAGGAGCAATGGCAGTACAATGCGATGCAATGCATGCTGAATTCAGAG
GATGTGATTGAAGGACCAAAAGCATTTGCACAGAAACGCACACCAGAATGGAAAGGGCGTTAA

Upstream 100 bases:

>100_bases
GTCATGAACTACTGCAACGCATTGTTAGTGATGCCAATCAGATTATTCGTGAGCGTCTTAACCAATTTATTTAAATTATC
AATTAAAAAATCTAAGGAGA

Downstream 100 bases:

>100_bases
TTTTCAAATTAAAAATGCCACATGGAATGAGGATCAAGAGATGCATCCAATGGTTCATGCACAGAACACCCCTGATAAAG
CGGCTTGTATCTTTGCCAGT

Product: enoyl-CoA hydratase

Products: L-Carnitine.; L-carnitinyl-CoA [C]

Alternate protein names: Crotonobetainyl-CoA hydratase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAMEYHFIQVEKQQHLTIITLNRPASFNALNASAHEELAQAFDQFQNDDEQWVAIVTGVGEKAFCAGHDLKQQAAGGGLV
TPQSGFAGLTARFDLTKPVIAAVNGVAMGGGFELALACDLIIASENAVFALPEPRVGLAALAGGMQRLPQVIGLKRSMGM
LLTGRRVSAQEGFELGFVNEVTSGPVLEAAKRWANEILACSPLSIRATKQTVLRGLESSVEQAMQEQWQYNAMQCMLNSE
DVIEGPKAFAQKRTPEWKGR

Sequences:

>Translated_260_residues
MAMEYHFIQVEKQQHLTIITLNRPASFNALNASAHEELAQAFDQFQNDDEQWVAIVTGVGEKAFCAGHDLKQQAAGGGLV
TPQSGFAGLTARFDLTKPVIAAVNGVAMGGGFELALACDLIIASENAVFALPEPRVGLAALAGGMQRLPQVIGLKRSMGM
LLTGRRVSAQEGFELGFVNEVTSGPVLEAAKRWANEILACSPLSIRATKQTVLRGLESSVEQAMQEQWQYNAMQCMLNSE
DVIEGPKAFAQKRTPEWKGR
>Mature_259_residues
AMEYHFIQVEKQQHLTIITLNRPASFNALNASAHEELAQAFDQFQNDDEQWVAIVTGVGEKAFCAGHDLKQQAAGGGLVT
PQSGFAGLTARFDLTKPVIAAVNGVAMGGGFELALACDLIIASENAVFALPEPRVGLAALAGGMQRLPQVIGLKRSMGML
LTGRRVSAQEGFELGFVNEVTSGPVLEAAKRWANEILACSPLSIRATKQTVLRGLESSVEQAMQEQWQYNAMQCMLNSED
VIEGPKAFAQKRTPEWKGR

Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=262, Percent_Identity=34.7328244274809, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI70995211, Length=258, Percent_Identity=31.3953488372093, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI20127408, Length=192, Percent_Identity=32.2916666666667, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI150378541, Length=257, Percent_Identity=28.7937743190661, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI68989263, Length=186, Percent_Identity=32.7956989247312, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI4502327, Length=259, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI213417737, Length=232, Percent_Identity=28.448275862069, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI157694516, Length=232, Percent_Identity=28.448275862069, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI37594469, Length=178, Percent_Identity=31.4606741573034, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI37594471, Length=175, Percent_Identity=30.2857142857143, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI221136756, Length=239, Percent_Identity=27.6150627615063, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI221136753, Length=239, Percent_Identity=27.6150627615063, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI221307494, Length=237, Percent_Identity=27.8481012658228, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI31542718, Length=247, Percent_Identity=29.5546558704453, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4757966, Length=237, Percent_Identity=26.5822784810127, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI51538581, Length=237, Percent_Identity=26.5822784810127, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI25453481, Length=237, Percent_Identity=26.5822784810127, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI51538573, Length=237, Percent_Identity=26.5822784810127, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI260274832, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI45643119, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI260275230, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4757968, Length=190, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI49355787, Length=190, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI116235487, Length=236, Percent_Identity=26.6949152542373, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157694520, Length=202, Percent_Identity=28.2178217821782, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI261878539, Length=92, Percent_Identity=38.0434782608696, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI221142681, Length=265, Percent_Identity=41.8867924528302, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787659, Length=253, Percent_Identity=37.9446640316205, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788597, Length=259, Percent_Identity=33.2046332046332, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=32.3308270676692, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082183, Length=264, Percent_Identity=26.8939393939394, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1788682, Length=215, Percent_Identity=29.7674418604651, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790281, Length=133, Percent_Identity=33.0827067669173, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=260, Percent_Identity=36.1538461538462, Blast_Score=147, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=37.5, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17560910, Length=253, Percent_Identity=29.6442687747036, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17540714, Length=227, Percent_Identity=30.3964757709251, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17534483, Length=278, Percent_Identity=27.6978417266187, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17536985, Length=271, Percent_Identity=27.3062730627306, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17558304, Length=251, Percent_Identity=27.0916334661355, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144276, Length=202, Percent_Identity=31.6831683168317, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17508951, Length=202, Percent_Identity=31.6831683168317, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17508953, Length=202, Percent_Identity=31.6831683168317, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=220, Percent_Identity=28.1818181818182, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=241, Percent_Identity=25.7261410788382, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320241, Length=195, Percent_Identity=28.2051282051282, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20129971, Length=258, Percent_Identity=34.4961240310078, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653477, Length=258, Percent_Identity=34.4961240310078, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21357171, Length=259, Percent_Identity=33.5907335907336, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653139, Length=259, Percent_Identity=31.6602316602317, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24650670, Length=280, Percent_Identity=31.0714285714286, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24654903, Length=191, Percent_Identity=29.3193717277487, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19920382, Length=226, Percent_Identity=26.9911504424779, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571730, Length=182, Percent_Identity=30.2197802197802, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28571729, Length=182, Percent_Identity=30.2197802197802, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19922422, Length=264, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921000, Length=195, Percent_Identity=30.2564102564103, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24583077, Length=195, Percent_Identity=30.2564102564103, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24583079, Length=195, Percent_Identity=30.2564102564103, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022852
- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 28089; Mature: 27957

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMEYHFIQVEKQQHLTIITLNRPASFNALNASAHEELAQAFDQFQNDDEQWVAIVTGVG
CCCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCC
EKAFCAGHDLKQQAAGGGLVTPQSGFAGLTARFDLTKPVIAAVNGVAMGGGFELALACDL
CCCEECCCCHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHCCEEECCCEEEEEEEEE
IIASENAVFALPEPRVGLAALAGGMQRLPQVIGLKRSMGMLLTGRRVSAQEGFELGFVNE
EEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHH
VTSGPVLEAAKRWANEILACSPLSIRATKQTVLRGLESSVEQAMQEQWQYNAMQCMLNSE
CCCCHHHHHHHHHHHHHEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DVIEGPKAFAQKRTPEWKGR
HHHCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AMEYHFIQVEKQQHLTIITLNRPASFNALNASAHEELAQAFDQFQNDDEQWVAIVTGVG
CCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCC
EKAFCAGHDLKQQAAGGGLVTPQSGFAGLTARFDLTKPVIAAVNGVAMGGGFELALACDL
CCCEECCCCHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHCCEEECCCEEEEEEEEE
IIASENAVFALPEPRVGLAALAGGMQRLPQVIGLKRSMGMLLTGRRVSAQEGFELGFVNE
EEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHH
VTSGPVLEAAKRWANEILACSPLSIRATKQTVLRGLESSVEQAMQEQWQYNAMQCMLNSE
CCCCHHHHHHHHHHHHHEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DVIEGPKAFAQKRTPEWKGR
HHHCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Carnitine; D-carnitinyl-CoA [C]

Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]

General reaction: Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA