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The map label for this gene is soxC [H]

Identifier: 50084678

GI number: 50084678

Start: 1507661

End: 1508941

Strand: Direct

Name: soxC [H]

Synonym: ACIAD1510

Alternate gene names: 50084678

Gene position: 1507661-1508941 (Clockwise)

Preceding gene: 50084677

Following gene: 50084680

Centisome position: 41.9

GC content: 39.73

Gene sequence:

>1281_bases
CTGGAGTTAAAAATGAATGATATTAACCAACACAGTTTTTTAAAATTAGGTAGCGTAAGACACATTCAAAGCGAGCAAGA
AGCACTTGAAATTGCAAAAGAGATGGCAAATCAACTGAATCAATTTGCTCGAAACCCAAGTTATAACAAGACCGTACCTT
ATGATCAGGCGCGTTTAATTTCAGAAGCTGGTTTAACCGCGATTATTGTACCTAAGCAATTTGGAGGCTTAGGTGCCAGT
ATTTCAACATTAGTGAATGTGGTGAAAATTATTTCATCTGCCGATGGTGGTGTAGGGCAGTTATTACAGATTCACTTCAC
TATGTTCCGAGGAATTTTAACTGGCTATGACGATGAAATCCGTGATCAATTACTTGCCGATGTATTAAGTGGAAAACGTT
TGGGCAATGCACTTGCAGAAGTGGGTGGTAAAGATAAATTCCAGCATAAGACGCGAGTAGAGCGAAACTCAGAAGGAAAA
TTAATTTTAAACGGTAGTAAATTCTATTCTACGGGTTCTTTACTTGCAGAATGGATTTCTTTATTTGCGGGTAGTGATGA
CGGACCAGTTTCAATTTTAATTCATCGAGATACGCAGGGAGTAGAGTTGCTCAATGACTGGGATGCGATGGGCCAAAATA
ATAGCGTCAGTGGCACTGTTAATTTTAAAGATGTGGTTGTTGATGAACGTTATGTGGCCAAACGAAATACAGGTGGTTTA
GGTACGGTTTTACGTACAGGGCTTACTTGGCCTCAGATTTTACATGCTGCAATGGACACAGGAATTGCCAAAGGGGCATT
ACAAGGCGGGATTGATTATTTACAACATCATGCTCGTCCATGGGTGGAAAGTGGCGTCGATTCACCTACACATGAATCTC
ATATCATTAAACAAATTGGTGAGTTTGCTGTTTTGGTTCGTTCAGCCGAGGCATTATTGGATCGTTCGGCACAGATTTTT
GAACAGCATTTGGCAAATGTAGAAGATGAAGACTTACAAACAGAACTGATTTTATCGGTTGCTGCTACACGAAGTCAGTC
TGATCATGCATCTTTAAAAATTTCGAGTGAAATTTTTGGATTACTCGGGGCAAGTTCAACCTTGTCGAAGTGGAATCTAG
ACCGTTTCTGGCGTAATGCACGAACCCATACCACTCATGATCCAATTCGCTGGAGGCTCTATCATGTTGGAAATTATTAT
TTAAATAATATTCCACCAGGAGAATACAACTCCGTACTTCTAAAGAAGCAGGCGGAAAATGTGACTAAATTTAGTAAATA
A

Upstream 100 bases:

>100_bases
TCATCCTCAACATACATATACCAAAACTTTGCTTACACATGCGCCAAGCTTGTTTAAAAACAACCTAATTGAAGTTAGTG
CATAAAGAAGAACAGATTTT

Downstream 100 bases:

>100_bases
CCGAGTTTGAAAGTAAATATGATACTCGGAAACGTCATCTGCAACCTGCATGGTTTAAACAAGAGACTGTTTCTACGAGA
GGTTTTAATAAATCCAAGAA

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: DBT sulfur dioxygenase [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MELKMNDINQHSFLKLGSVRHIQSEQEALEIAKEMANQLNQFARNPSYNKTVPYDQARLISEAGLTAIIVPKQFGGLGAS
ISTLVNVVKIISSADGGVGQLLQIHFTMFRGILTGYDDEIRDQLLADVLSGKRLGNALAEVGGKDKFQHKTRVERNSEGK
LILNGSKFYSTGSLLAEWISLFAGSDDGPVSILIHRDTQGVELLNDWDAMGQNNSVSGTVNFKDVVVDERYVAKRNTGGL
GTVLRTGLTWPQILHAAMDTGIAKGALQGGIDYLQHHARPWVESGVDSPTHESHIIKQIGEFAVLVRSAEALLDRSAQIF
EQHLANVEDEDLQTELILSVAATRSQSDHASLKISSEIFGLLGASSTLSKWNLDRFWRNARTHTTHDPIRWRLYHVGNYY
LNNIPPGEYNSVLLKKQAENVTKFSK

Sequences:

>Translated_426_residues
MELKMNDINQHSFLKLGSVRHIQSEQEALEIAKEMANQLNQFARNPSYNKTVPYDQARLISEAGLTAIIVPKQFGGLGAS
ISTLVNVVKIISSADGGVGQLLQIHFTMFRGILTGYDDEIRDQLLADVLSGKRLGNALAEVGGKDKFQHKTRVERNSEGK
LILNGSKFYSTGSLLAEWISLFAGSDDGPVSILIHRDTQGVELLNDWDAMGQNNSVSGTVNFKDVVVDERYVAKRNTGGL
GTVLRTGLTWPQILHAAMDTGIAKGALQGGIDYLQHHARPWVESGVDSPTHESHIIKQIGEFAVLVRSAEALLDRSAQIF
EQHLANVEDEDLQTELILSVAATRSQSDHASLKISSEIFGLLGASSTLSKWNLDRFWRNARTHTTHDPIRWRLYHVGNYY
LNNIPPGEYNSVLLKKQAENVTKFSK
>Mature_426_residues
MELKMNDINQHSFLKLGSVRHIQSEQEALEIAKEMANQLNQFARNPSYNKTVPYDQARLISEAGLTAIIVPKQFGGLGAS
ISTLVNVVKIISSADGGVGQLLQIHFTMFRGILTGYDDEIRDQLLADVLSGKRLGNALAEVGGKDKFQHKTRVERNSEGK
LILNGSKFYSTGSLLAEWISLFAGSDDGPVSILIHRDTQGVELLNDWDAMGQNNSVSGTVNFKDVVVDERYVAKRNTGGL
GTVLRTGLTWPQILHAAMDTGIAKGALQGGIDYLQHHARPWVESGVDSPTHESHIIKQIGEFAVLVRSAEALLDRSAQIF
EQHLANVEDEDLQTELILSVAATRSQSDHASLKISSEIFGLLGASSTLSKWNLDRFWRNARTHTTHDPIRWRLYHVGNYY
LNNIPPGEYNSVLLKKQAENVTKFSK

Specific function: Part of a pathway to remove covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Sulfur dioxygenase which converts DBT to DBT-sulfone (DBTO2 or DBT 5,5-dioxide) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557233, Length=379, Percent_Identity=21.6358839050132, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=333, Percent_Identity=22.8228228228228, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=223, Percent_Identity=26.457399103139, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=362, Percent_Identity=22.0994475138122, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=328, Percent_Identity=22.8658536585366, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356377, Length=362, Percent_Identity=22.0994475138122, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 47097; Mature: 47097

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKMNDINQHSFLKLGSVRHIQSEQEALEIAKEMANQLNQFARNPSYNKTVPYDQARLI
CCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
SEAGLTAIIVPKQFGGLGASISTLVNVVKIISSADGGVGQLLQIHFTMFRGILTGYDDEI
HHCCCEEEEECHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHH
RDQLLADVLSGKRLGNALAEVGGKDKFQHKTRVERNSEGKLILNGSKFYSTGSLLAEWIS
HHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHH
LFAGSDDGPVSILIHRDTQGVELLNDWDAMGQNNSVSGTVNFKDVVVDERYVAKRNTGGL
HHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEHHHHEECCHHHHHCCCCCH
GTVLRTGLTWPQILHAAMDTGIAKGALQGGIDYLQHHARPWVESGVDSPTHESHIIKQIG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHH
EFAVLVRSAEALLDRSAQIFEQHLANVEDEDLQTELILSVAATRSQSDHASLKISSEIFG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHH
LLGASSTLSKWNLDRFWRNARTHTTHDPIRWRLYHVGNYYLNNIPPGEYNSVLLKKQAEN
HHCCCCHHHHCCHHHHHHCCCCCCCCCCEEEEEEEECCHHCCCCCCCCCHHHHHHHHHHH
VTKFSK
HHHCCC
>Mature Secondary Structure
MELKMNDINQHSFLKLGSVRHIQSEQEALEIAKEMANQLNQFARNPSYNKTVPYDQARLI
CCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
SEAGLTAIIVPKQFGGLGASISTLVNVVKIISSADGGVGQLLQIHFTMFRGILTGYDDEI
HHCCCEEEEECHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHH
RDQLLADVLSGKRLGNALAEVGGKDKFQHKTRVERNSEGKLILNGSKFYSTGSLLAEWIS
HHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHH
LFAGSDDGPVSILIHRDTQGVELLNDWDAMGQNNSVSGTVNFKDVVVDERYVAKRNTGGL
HHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEHHHHEECCHHHHHCCCCCH
GTVLRTGLTWPQILHAAMDTGIAKGALQGGIDYLQHHARPWVESGVDSPTHESHIIKQIG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHH
EFAVLVRSAEALLDRSAQIFEQHLANVEDEDLQTELILSVAATRSQSDHASLKISSEIFG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHH
LLGASSTLSKWNLDRFWRNARTHTTHDPIRWRLYHVGNYYLNNIPPGEYNSVLLKKQAEN
HHCCCCHHHHCCHHHHHHCCCCCCCCCCEEEEEEEECCHHCCCCCCCCCHHHHHHHHHHH
VTKFSK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961424; 7574582 [H]