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The map label for this gene is lktD [H]

Identifier: 50084660

GI number: 50084660

Start: 1487917

End: 1489107

Strand: Direct

Name: lktD [H]

Synonym: ACIAD1489

Alternate gene names: 50084660

Gene position: 1487917-1489107 (Clockwise)

Preceding gene: 50084659

Following gene: 50084661

Centisome position: 41.35

GC content: 39.46

Gene sequence:

>1191_bases
ATGAGCGATCAACAACAAGAAAAAGCCCGCTCATTAAATGTTTCTTATAAAGAGCCACCTTTGCCAAGAGCCAGTTTAAT
CATCTGGATTGTCGGAATTGCCTTGGTGATTTTAGTGGTTTGGGCATGGGTGTTTAAGCTTGAAGAAGTTTCTACAGGAA
CAGGTAAAGTCATTCCATCTTCAAAAGAACAAATGATTCAGTCTTTAGATGGTGGGATTCTGACCAAACTAGATGTAAAA
GAAGGTGATATTGTTCAGAAGGGTCAAATTCTGGCTCAACTTGATCCAACACGCTTTGCATCAAATGTAGGTGAGTCTCA
GTCATTACTGATGGCGGCTCAGGCAACCTCTGCCAGATTAAGAGCTGAAGTCAACGGAACACCTTTGGCCTTTCCTGATG
AAGTCAAGCAGGAGCCAAAACTGGTACAAGAAGAAACAGCTTTATATAATTCACGTCGTGCAAATCTTGAAGAAACGGTC
GCTGGATTAAAACAGGCCTTGCATTTGGTTCAGCAAGAACTCGTGATGACTGAACCATTGGTTGCCAAGGGTGCTGCGAG
TGAAGTTGAAGTACTACGACTAAAACGTGAAGCAAATGATTTACAAAATAAGATCAACGATGCACGTAGCAGTTACTACG
TAAAAGCACGTGAAGAGTTATCTAAATCAAATACTGATGTTCAAACTCAGCAGCAAGTCATTAAAGGACGAACTGATACT
TTAAATAGAACTGTATTTAAAGCACCTGTACGCGGTGTTGTAAAAGAAATTACAGTAACGACTCTAGGTGGTGTTGTTCC
GCAAAACGGTAAGTTAATGACCATCGTACCACTAGATGAGCAACTCTTAATTGAAGCAAGAATTTTGCCACGTGATATTG
CCTTTATTCGCCCTGGTCAGGAAGCGCTAGTTAAAATTACGGCTTATGACTATTCAATTTATGGTGGTATGAAGGGTAAA
GTGACTGTGATTTCACCAGATACAATTCGTGATGAAGTGAAACAGGATCAGTTCTATTATCGTGTATATATTCGTACAGA
CTCCGATAAGTTATATAATAAGGCTGGTAAAGCTTTTAATATCACACCAGGTATGGTTGCTACAGTAGATATTAAAACTG
GTCAGAAAACCATTATGGATTACTTATTGAAACCATTCAATAAGGCCAAAGAAGCGTTAAGAGAACGTTAA

Upstream 100 bases:

>100_bases
TTGTGATCAATGATGGAAAGATCGTGATGGATGGTCCACGTGACCAAATATTAAAACAGTCAACTCAACCTAAAGCAGTC
ACACAACAGGGGACACAATC

Downstream 100 bases:

>100_bases
AAATAAATAAAATCCTCGACATGTTCGAGGATTTTTTTATCCTCTAAAAAATATGAAATTGCGTATAATGGCTGAGCTTG
TATCAATTGATTGAGTTTTA

Product: protein secretion efflux system ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSDQQQEKARSLNVSYKEPPLPRASLIIWIVGIALVILVVWAWVFKLEEVSTGTGKVIPSSKEQMIQSLDGGILTKLDVK
EGDIVQKGQILAQLDPTRFASNVGESQSLLMAAQATSARLRAEVNGTPLAFPDEVKQEPKLVQEETALYNSRRANLEETV
AGLKQALHLVQQELVMTEPLVAKGAASEVEVLRLKREANDLQNKINDARSSYYVKAREELSKSNTDVQTQQQVIKGRTDT
LNRTVFKAPVRGVVKEITVTTLGGVVPQNGKLMTIVPLDEQLLIEARILPRDIAFIRPGQEALVKITAYDYSIYGGMKGK
VTVISPDTIRDEVKQDQFYYRVYIRTDSDKLYNKAGKAFNITPGMVATVDIKTGQKTIMDYLLKPFNKAKEALRER

Sequences:

>Translated_396_residues
MSDQQQEKARSLNVSYKEPPLPRASLIIWIVGIALVILVVWAWVFKLEEVSTGTGKVIPSSKEQMIQSLDGGILTKLDVK
EGDIVQKGQILAQLDPTRFASNVGESQSLLMAAQATSARLRAEVNGTPLAFPDEVKQEPKLVQEETALYNSRRANLEETV
AGLKQALHLVQQELVMTEPLVAKGAASEVEVLRLKREANDLQNKINDARSSYYVKAREELSKSNTDVQTQQQVIKGRTDT
LNRTVFKAPVRGVVKEITVTTLGGVVPQNGKLMTIVPLDEQLLIEARILPRDIAFIRPGQEALVKITAYDYSIYGGMKGK
VTVISPDTIRDEVKQDQFYYRVYIRTDSDKLYNKAGKAFNITPGMVATVDIKTGQKTIMDYLLKPFNKAKEALRER
>Mature_395_residues
SDQQQEKARSLNVSYKEPPLPRASLIIWIVGIALVILVVWAWVFKLEEVSTGTGKVIPSSKEQMIQSLDGGILTKLDVKE
GDIVQKGQILAQLDPTRFASNVGESQSLLMAAQATSARLRAEVNGTPLAFPDEVKQEPKLVQEETALYNSRRANLEETVA
GLKQALHLVQQELVMTEPLVAKGAASEVEVLRLKREANDLQNKINDARSSYYVKAREELSKSNTDVQTQQQVIKGRTDTL
NRTVFKAPVRGVVKEITVTTLGGVVPQNGKLMTIVPLDEQLLIEARILPRDIAFIRPGQEALVKITAYDYSIYGGMKGKV
TVISPDTIRDEVKQDQFYYRVYIRTDSDKLYNKAGKAFNITPGMVATVDIKTGQKTIMDYLLKPFNKAKEALRER

Specific function: Involved in the transport of the Leukotoxin [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44100; Mature: 43969

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQQQEKARSLNVSYKEPPLPRASLIIWIVGIALVILVVWAWVFKLEEVSTGTGKVIPS
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SKEQMIQSLDGGILTKLDVKEGDIVQKGQILAQLDPTRFASNVGESQSLLMAAQATSARL
CHHHHHHHCCCCEEEEEECCCCCCEECCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHE
RAEVNGTPLAFPDEVKQEPKLVQEETALYNSRRANLEETVAGLKQALHLVQQELVMTEPL
EEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCH
VAKGAASEVEVLRLKREANDLQNKINDARSSYYVKAREELSKSNTDVQTQQQVIKGRTDT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHCCCCCHHHHHHHHCCCCHH
LNRTVFKAPVRGVVKEITVTTLGGVVPQNGKLMTIVPLDEQLLIEARILPRDIAFIRPGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHCCCHHEEECCCH
EALVKITAYDYSIYGGMKGKVTVISPDTIRDEVKQDQFYYRVYIRTDSDKLYNKAGKAFN
HHEEEEEEEEEEEECCCCCCEEEECCHHHHHHHHCCCEEEEEEEEECCHHHHHHCCCEEE
ITPGMVATVDIKTGQKTIMDYLLKPFNKAKEALRER
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDQQQEKARSLNVSYKEPPLPRASLIIWIVGIALVILVVWAWVFKLEEVSTGTGKVIPS
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SKEQMIQSLDGGILTKLDVKEGDIVQKGQILAQLDPTRFASNVGESQSLLMAAQATSARL
CHHHHHHHCCCCEEEEEECCCCCCEECCCEEEEECHHHHHHHCCCCHHHHHHHHHHHHHE
RAEVNGTPLAFPDEVKQEPKLVQEETALYNSRRANLEETVAGLKQALHLVQQELVMTEPL
EEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCH
VAKGAASEVEVLRLKREANDLQNKINDARSSYYVKAREELSKSNTDVQTQQQVIKGRTDT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHCCCCCHHHHHHHHCCCCHH
LNRTVFKAPVRGVVKEITVTTLGGVVPQNGKLMTIVPLDEQLLIEARILPRDIAFIRPGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHCCCHHEEECCCH
EALVKITAYDYSIYGGMKGKVTVISPDTIRDEVKQDQFYYRVYIRTDSDKLYNKAGKAFN
HHEEEEEEEEEEEECCCCCCEEEECCHHHHHHHHCCCEEEEEEEEECCHHHHHHCCCEEE
ITPGMVATVDIKTGQKTIMDYLLKPFNKAKEALRER
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040588; 2914876; 2707120 [H]