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The map label for this gene is lptA [H]

Identifier: 50084656

GI number: 50084656

Start: 1482810

End: 1483286

Strand: Direct

Name: lptA [H]

Synonym: ACIAD1485

Alternate gene names: 50084656

Gene position: 1482810-1483286 (Clockwise)

Preceding gene: 50084655

Following gene: 50084657

Centisome position: 41.2

GC content: 43.61

Gene sequence:

>477_bases
ATGTCTTGTTCGGCAGCTTTTGCTGTTCCATCAGATCGAAATCAGCCAATTTCGTTGGTGGCCGATCATGCAACATACAA
TGATAAAACGGGAGTCACAACCTATACTGGTAATGTTGTGATTGAGCAGGGAACCATGAAGTTGCAAGCAGACTCGATTG
TAGGCCAACTCAATTCACAACGTCAGCTACAAACGATTAATGCAACAGGTCGTCCAGCTAAGTTTCAACAGCAAATTAAT
GCTCAAAAGGGCATTGCTCGCGGTGAAGCACAAAAGATTGTTTATAATGCTGAAACAGGAATCATCACGCTGAGTGGAAA
TGCTTATCTGAATCAGGATGGGGCAAGTGTTCGCGGAAATACGCTTCGTTACAGTATGAATAAGGGTGATATTGAAGCAC
AAGGTTCAGGCTCTAATCGTGTACAACTGGTGATTCCACCATCTGCATCTAAAAGCTTTCCAGGAGCACGTGACTAA

Upstream 100 bases:

>100_bases
TACGAGTTTTTTAATATTCGAGGAAAGTATGCACCGAATTCTTAACTTATTTTGCACAACAGCTTTCCTTAAAAAAGTTG
CTCCAGTGGCACTATTGGGA

Downstream 100 bases:

>100_bases
TGGAGCAAATCGCGCAACAACAACCTCAGACTTTATGCATTAAGCATCTTGCAAAGAATTACAGCAAACGTTGGGTGGTA
AAAGACGTATCGTTTGAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSCSAAFAVPSDRNQPISLVADHATYNDKTGVTTYTGNVVIEQGTMKLQADSIVGQLNSQRQLQTINATGRPAKFQQQIN
AQKGIARGEAQKIVYNAETGIITLSGNAYLNQDGASVRGNTLRYSMNKGDIEAQGSGSNRVQLVIPPSASKSFPGARD

Sequences:

>Translated_158_residues
MSCSAAFAVPSDRNQPISLVADHATYNDKTGVTTYTGNVVIEQGTMKLQADSIVGQLNSQRQLQTINATGRPAKFQQQIN
AQKGIARGEAQKIVYNAETGIITLSGNAYLNQDGASVRGNTLRYSMNKGDIEAQGSGSNRVQLVIPPSASKSFPGARD
>Mature_157_residues
SCSAAFAVPSDRNQPISLVADHATYNDKTGVTTYTGNVVIEQGTMKLQADSIVGQLNSQRQLQTINATGRPAKFQQQINA
QKGIARGEAQKIVYNAETGIITLSGNAYLNQDGASVRGNTLRYSMNKGDIEAQGSGSNRVQLVIPPSASKSFPGARD

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=144, Percent_Identity=32.6388888888889, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 16789; Mature: 16658

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCSAAFAVPSDRNQPISLVADHATYNDKTGVTTYTGNVVIEQGTMKLQADSIVGQLNSQ
CCCCCEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCEEEECCCEEEEHHHHHHCCCCC
RQLQTINATGRPAKFQQQINAQKGIARGEAQKIVYNAETGIITLSGNAYLNQDGASVRGN
CEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCEEECCCCCCCCCC
TLRYSMNKGDIEAQGSGSNRVQLVIPPSASKSFPGARD
EEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SCSAAFAVPSDRNQPISLVADHATYNDKTGVTTYTGNVVIEQGTMKLQADSIVGQLNSQ
CCCCEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCEEEECCCEEEEHHHHHHCCCCC
RQLQTINATGRPAKFQQQINAQKGIARGEAQKIVYNAETGIITLSGNAYLNQDGASVRGN
CEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCEEECCCCCCCCCC
TLRYSMNKGDIEAQGSGSNRVQLVIPPSASKSFPGARD
EEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]