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The map label for this gene is salR [H]

Identifier: 50084602

GI number: 50084602

Start: 1421250

End: 1422140

Strand: Direct

Name: salR [H]

Synonym: ACIAD1425

Alternate gene names: 50084602

Gene position: 1421250-1422140 (Clockwise)

Preceding gene: 50084601

Following gene: 50084609

Centisome position: 39.49

GC content: 35.35

Gene sequence:

>891_bases
GTGGACTTAAGCCTGATCCGTATTTTTATTTGTGTTTATGAAAATAAAAATATCAGTAAAGCCGCTGAGATTTTAAATCT
GAGTCAACCTTCTGTTACCTATAATTTAAATCGATTACGTAAGCATTTAAATAATCCTTTATTTGAACGCACGCAATATG
GTGTGGAAGCAACTAAATTATCGCATGAATTATATCCTGTATTTAAAGAGTCGATTTTAAAAATTGAAATAGCAGTCGAT
GAGGCATTAAATTTTAATCCACTCACTTCAAATAAAACCTTTCGAATTGGTTTATCAGATATTGGTGAAATTTGCTTGTT
ACCGACATTAATCGAATACTTACGAGCACATGCACCAAAAATAAAAATAGAAGTAGAAGAGATTAAAATTGATCAAGTCG
AAAAATGGTTAATCGAAGGATTTATTGATGTGGCTGTTTTTAATAGTACACATTTGGAGTTTAAGCATCTTGAATATGAA
ACTCTTTTTTTAGAGCGATATGTTGCACTGGTCAACATGAATCATCCGCGAATAAGAAGTACGCTCAGTTTTGATGCGTA
TTTGAATGAATCTCATGTGGCGATAAAGTCATCTACCGGGCATACTCAGGTCGATCATGTATTAAAACTAATGGGGCATC
AGCGTAAAATTGCCTTGGAAGTGCCACATTTTGGAGTTTTACAAGGTGTGCTGGATAAAACAGATTTGATGGTGACGCTG
CCCAGTCGTGCTGCACAGCAATATTTAAATCAATCCCATGTCCGTGTTTTGGAGTTGCCGTTTCAAATGTCTGAATTTTA
TGTGGGCTTACATTGGTTTGCCCAAACCAATGAGCCCCTTGCTCGGATATGGTTGATTCAAACCTGTAAAAAGGTTATTT
CAGTTTTGTAA

Upstream 100 bases:

>100_bases
GTTTTGAACGACTTGTGCCTTTAAAACAATTCTATTTTGAAAGAGTTGAATAAAAGTGTTTATGATAGGATTAAATTAAA
ATCATGGAAGATTCTAAAAC

Downstream 100 bases:

>100_bases
GACCGCGGGCTAAGCCCGGCAGTCTAAACAATTAATCATGACTGGCTTCAATAATTTTAGTCGCCAATTCCTGAGGGCGG
GTAAACATTGCTTCATGGCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDLSLIRIFICVYENKNISKAAEILNLSQPSVTYNLNRLRKHLNNPLFERTQYGVEATKLSHELYPVFKESILKIEIAVD
EALNFNPLTSNKTFRIGLSDIGEICLLPTLIEYLRAHAPKIKIEVEEIKIDQVEKWLIEGFIDVAVFNSTHLEFKHLEYE
TLFLERYVALVNMNHPRIRSTLSFDAYLNESHVAIKSSTGHTQVDHVLKLMGHQRKIALEVPHFGVLQGVLDKTDLMVTL
PSRAAQQYLNQSHVRVLELPFQMSEFYVGLHWFAQTNEPLARIWLIQTCKKVISVL

Sequences:

>Translated_296_residues
MDLSLIRIFICVYENKNISKAAEILNLSQPSVTYNLNRLRKHLNNPLFERTQYGVEATKLSHELYPVFKESILKIEIAVD
EALNFNPLTSNKTFRIGLSDIGEICLLPTLIEYLRAHAPKIKIEVEEIKIDQVEKWLIEGFIDVAVFNSTHLEFKHLEYE
TLFLERYVALVNMNHPRIRSTLSFDAYLNESHVAIKSSTGHTQVDHVLKLMGHQRKIALEVPHFGVLQGVLDKTDLMVTL
PSRAAQQYLNQSHVRVLELPFQMSEFYVGLHWFAQTNEPLARIWLIQTCKKVISVL
>Mature_296_residues
MDLSLIRIFICVYENKNISKAAEILNLSQPSVTYNLNRLRKHLNNPLFERTQYGVEATKLSHELYPVFKESILKIEIAVD
EALNFNPLTSNKTFRIGLSDIGEICLLPTLIEYLRAHAPKIKIEVEEIKIDQVEKWLIEGFIDVAVFNSTHLEFKHLEYE
TLFLERYVALVNMNHPRIRSTLSFDAYLNESHVAIKSSTGHTQVDHVLKLMGHQRKIALEVPHFGVLQGVLDKTDLMVTL
PSRAAQQYLNQSHVRVLELPFQMSEFYVGLHWFAQTNEPLARIWLIQTCKKVISVL

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=22.9235880398671, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790147, Length=303, Percent_Identity=22.4422442244224, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081904, Length=181, Percent_Identity=26.5193370165746, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=246, Percent_Identity=21.9512195121951, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34178; Mature: 34178

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSLIRIFICVYENKNISKAAEILNLSQPSVTYNLNRLRKHLNNPLFERTQYGVEATKL
CCHHHEEEEEEEECCCCHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHHHHHHCCCHHHHH
SHELYPVFKESILKIEIAVDEALNFNPLTSNKTFRIGLSDIGEICLLPTLIEYLRAHAPK
HHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCE
IKIEVEEIKIDQVEKWLIEGFIDVAVFNSTHLEFKHLEYETLFLERYVALVNMNHPRIRS
EEEEEEEECHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHH
TLSFDAYLNESHVAIKSSTGHTQVDHVLKLMGHQRKIALEVPHFGVLQGVLDKTDLMVTL
EEEEHHEECCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCEEEEC
PSRAAQQYLNQSHVRVLELPFQMSEFYVGLHWFAQTNEPLARIWLIQTCKKVISVL
CHHHHHHHHCCCCCEEEECCHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLSLIRIFICVYENKNISKAAEILNLSQPSVTYNLNRLRKHLNNPLFERTQYGVEATKL
CCHHHEEEEEEEECCCCHHHHHHHHCCCCCCEEEEHHHHHHHHCCHHHHHHHCCCHHHHH
SHELYPVFKESILKIEIAVDEALNFNPLTSNKTFRIGLSDIGEICLLPTLIEYLRAHAPK
HHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCE
IKIEVEEIKIDQVEKWLIEGFIDVAVFNSTHLEFKHLEYETLFLERYVALVNMNHPRIRS
EEEEEEEECHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHH
TLSFDAYLNESHVAIKSSTGHTQVDHVLKLMGHQRKIALEVPHFGVLQGVLDKTDLMVTL
EEEEHHEECCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCEEEEC
PSRAAQQYLNQSHVRVLELPFQMSEFYVGLHWFAQTNEPLARIWLIQTCKKVISVL
CHHHHHHHHCCCCCEEEECCHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]