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The map label for this gene is cysQ [H]

Identifier: 50084565

GI number: 50084565

Start: 1382955

End: 1383815

Strand: Direct

Name: cysQ [H]

Synonym: ACIAD1387

Alternate gene names: 50084565

Gene position: 1382955-1383815 (Clockwise)

Preceding gene: 50084560

Following gene: 50084566

Centisome position: 38.43

GC content: 33.8

Gene sequence:

>861_bases
ATGTTTATTCAGACTGATCAATCAATAACAGGTAATTTAATTAATCAATTATTGCCGATTTTAGAGCAAGCTTCTAATTT
GTTAAATAACGAGTATGAAAATTATATTTCAGGAAATCAGTTAGATATCCAAAAAAAAACAGATGAATCTCCTGTAACGC
AAGCTGATCTTAAAATAAATCATTTTCTAGTAACAGAGTTGGCCAGAATAACACCTGATTACCCTGTATTATCTGAGGAA
GGTGACAATACTCAGCGATGTTCATGGAATATTTGCTGGATGTTGGATCCTTTAGATGGGACAAAAGAGTTTATTCAGCA
AAGAGATGAGTTCACTATCAATCTGAGTTTAATCGAAGATTCATATACTTCATTTTCTGTGATTGTTGTTCCGCGTGAGC
AACAGATGTATATAGGATATACACATGAATTGCCGTATAAATATCAGTTTAATTCTAAACAATGGTGGCGATATCATCAT
TCAATTGAGAGCCTGAATAATACGATTCAAGTTGGACTAAGCCATCGAAGTAAGAGTAGTAAATATCAAAAATTTATAGA
GTACTTAGAGAGTGACTATAAGATTGTTTGTCGTGAGGCTGGGAGTGCTTATAAATTTTGTATGATGCTAGAAGGTAAAA
TTGATTTCTATCCGAGATTTCATCCAACATCTGAATGGGATACAAGTGCTGGACAGGCATTGCTGGAAAGTATTGGGGGA
GGCTTAGTCTCTTTAAACGGTATTCCATTTAAATATAATGTACGTACCACCGTTTTAAACCAAGGCTTCATTGCGTATTC
AAAATCTGAGTATAGGCATTTGGTATTGGAGCTATTACAACAAATAGATTTTTCAAATTGA

Upstream 100 bases:

>100_bases
ATTATTGGATCCAATCGAAAAATAGATAAGATAATCTTCATTCAACAATGTTTAAAAATTTGAATATAATGATCTCTTGG
AAATAGGGCTTGTATTAACC

Downstream 100 bases:

>100_bases
GAGTTGTGCGCTGTATGATATAGTGAACTAACCAATAAAAATGATTTATAAATATCATGAGTTTAAAACTACTCCCGCCA
AGTATGTTGCAAGCAATTGA

Product: PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MFIQTDQSITGNLINQLLPILEQASNLLNNEYENYISGNQLDIQKKTDESPVTQADLKINHFLVTELARITPDYPVLSEE
GDNTQRCSWNICWMLDPLDGTKEFIQQRDEFTINLSLIEDSYTSFSVIVVPREQQMYIGYTHELPYKYQFNSKQWWRYHH
SIESLNNTIQVGLSHRSKSSKYQKFIEYLESDYKIVCREAGSAYKFCMMLEGKIDFYPRFHPTSEWDTSAGQALLESIGG
GLVSLNGIPFKYNVRTTVLNQGFIAYSKSEYRHLVLELLQQIDFSN

Sequences:

>Translated_286_residues
MFIQTDQSITGNLINQLLPILEQASNLLNNEYENYISGNQLDIQKKTDESPVTQADLKINHFLVTELARITPDYPVLSEE
GDNTQRCSWNICWMLDPLDGTKEFIQQRDEFTINLSLIEDSYTSFSVIVVPREQQMYIGYTHELPYKYQFNSKQWWRYHH
SIESLNNTIQVGLSHRSKSSKYQKFIEYLESDYKIVCREAGSAYKFCMMLEGKIDFYPRFHPTSEWDTSAGQALLESIGG
GLVSLNGIPFKYNVRTTVLNQGFIAYSKSEYRHLVLELLQQIDFSN
>Mature_286_residues
MFIQTDQSITGNLINQLLPILEQASNLLNNEYENYISGNQLDIQKKTDESPVTQADLKINHFLVTELARITPDYPVLSEE
GDNTQRCSWNICWMLDPLDGTKEFIQQRDEFTINLSLIEDSYTSFSVIVVPREQQMYIGYTHELPYKYQFNSKQWWRYHH
SIESLNNTIQVGLSHRSKSSKYQKFIEYLESDYKIVCREAGSAYKFCMMLEGKIDFYPRFHPTSEWDTSAGQALLESIGG
GLVSLNGIPFKYNVRTTVLNQGFIAYSKSEYRHLVLELLQQIDFSN

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=250, Percent_Identity=33.2, Blast_Score=121, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71995905, Length=258, Percent_Identity=24.8062015503876, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=258, Percent_Identity=24.8062015503876, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24664918, Length=243, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 33255; Mature: 33255

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIQTDQSITGNLINQLLPILEQASNLLNNEYENYISGNQLDIQKKTDESPVTQADLKIN
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCEEH
HFLVTELARITPDYPVLSEEGDNTQRCSWNICWMLDPLDGTKEFIQQRDEFTINLSLIED
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCEEEEEEEEEC
SYTSFSVIVVPREQQMYIGYTHELPYKYQFNSKQWWRYHHSIESLNNTIQVGLSHRSKSS
CCCEEEEEEEECCCEEEEEEEECCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCHH
KYQKFIEYLESDYKIVCREAGSAYKFCMMLEGKIDFYPRFHPTSEWDTSAGQALLESIGG
HHHHHHHHHHCCCEEEEECCCCCEEEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHCC
GLVSLNGIPFKYNVRTTVLNQGFIAYSKSEYRHLVLELLQQIDFSN
CEEEECCCCEEEEEEEEEEECCEEEECHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFIQTDQSITGNLINQLLPILEQASNLLNNEYENYISGNQLDIQKKTDESPVTQADLKIN
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCEEH
HFLVTELARITPDYPVLSEEGDNTQRCSWNICWMLDPLDGTKEFIQQRDEFTINLSLIED
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCEEEEEEEEEC
SYTSFSVIVVPREQQMYIGYTHELPYKYQFNSKQWWRYHHSIESLNNTIQVGLSHRSKSS
CCCEEEEEEEECCCEEEEEEEECCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCHH
KYQKFIEYLESDYKIVCREAGSAYKFCMMLEGKIDFYPRFHPTSEWDTSAGQALLESIGG
HHHHHHHHHHCCCEEEEECCCCCEEEEEEEECCEEECCCCCCCCCCCCHHHHHHHHHHCC
GLVSLNGIPFKYNVRTTVLNQGFIAYSKSEYRHLVLELLQQIDFSN
CEEEECCCCEEEEEEEEEEECCEEEECHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]