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The map label for this gene is fabZ [H]

Identifier: 50084559

GI number: 50084559

Start: 1377583

End: 1378071

Strand: Direct

Name: fabZ [H]

Synonym: ACIAD1381

Alternate gene names: 50084559

Gene position: 1377583-1378071 (Clockwise)

Preceding gene: 50084558

Following gene: 50084560

Centisome position: 38.28

GC content: 38.45

Gene sequence:

>489_bases
ATGATGACTGAGTCAAACACTCCTGCGTTTACGATCCCTGAATTGCCAATGGACATTCAAAAAATTCGTGAATATTTGCC
ACATCGCTATCCATTCCTATTGGTTGATCGTGTAGTTGAAGTTGGTGAAAATAATATTGTTGGCTATAAAAACGTTTCGA
TTAACGAAGAGTTTTTTCAGGGCCATTTTCCTGATTATCCGATTATGCCAGGTGTCTTGATTGTAGAGGCTTTGGCACAA
ATTTCTGGTATTTTGGGTTTTATTATGAATAATGAAACTCCTAAACCAGGTTCTTTGTTTCTGTTCGCAGGGGCTGAGAA
AGTTCGTTTCAAAAAACAAGTGGTTGCTGGTGATCAGCTCGTTTTAAAAGCTGAACTTGTCATGCAAAAACGTGGTATCT
ACAAATACAATTGTACTGCTACGGTTGATGGTAAAGTCGCTACAACCGCTGAAATTATAGTTTCGCATTTAAGAACAGAG
CAGGCATGA

Upstream 100 bases:

>100_bases
ATTAGCAGATGTGCCATTGACCCAAATCATGAAACGACTCGATCATATACAGACTCAAATTGAGTCTCTTGAATCAACTT
TTAAATTGCGTAAATAGAAT

Downstream 100 bases:

>100_bases
GCAATAACGACCTAATTCATTCTACCGCTATTATTGATACATCTGCAGTGATTGCTGCAGATGTTCAGATTGGGCCGTAT
TGTGTAATTGGTCCCAACGT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MMTESNTPAFTIPELPMDIQKIREYLPHRYPFLLVDRVVEVGENNIVGYKNVSINEEFFQGHFPDYPIMPGVLIVEALAQ
ISGILGFIMNNETPKPGSLFLFAGAEKVRFKKQVVAGDQLVLKAELVMQKRGIYKYNCTATVDGKVATTAEIIVSHLRTE
QA

Sequences:

>Translated_162_residues
MMTESNTPAFTIPELPMDIQKIREYLPHRYPFLLVDRVVEVGENNIVGYKNVSINEEFFQGHFPDYPIMPGVLIVEALAQ
ISGILGFIMNNETPKPGSLFLFAGAEKVRFKKQVVAGDQLVLKAELVMQKRGIYKYNCTATVDGKVATTAEIIVSHLRTE
QA
>Mature_162_residues
MMTESNTPAFTIPELPMDIQKIREYLPHRYPFLLVDRVVEVGENNIVGYKNVSINEEFFQGHFPDYPIMPGVLIVEALAQ
ISGILGFIMNNETPKPGSLFLFAGAEKVRFKKQVVAGDQLVLKAELVMQKRGIYKYNCTATVDGKVATTAEIIVSHLRTE
QA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=143, Percent_Identity=47.5524475524476, Blast_Score=137, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 18160; Mature: 18160

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTESNTPAFTIPELPMDIQKIREYLPHRYPFLLVDRVVEVGENNIVGYKNVSINEEFFQ
CCCCCCCCEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHC
GHFPDYPIMPGVLIVEALAQISGILGFIMNNETPKPGSLFLFAGAEKVRFKKQVVAGDQL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHCCCHH
VLKAELVMQKRGIYKYNCTATVDGKVATTAEIIVSHLRTEQA
HHHHHHHHHHCCCEEEECEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMTESNTPAFTIPELPMDIQKIREYLPHRYPFLLVDRVVEVGENNIVGYKNVSINEEFFQ
CCCCCCCCEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHC
GHFPDYPIMPGVLIVEALAQISGILGFIMNNETPKPGSLFLFAGAEKVRFKKQVVAGDQL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHCCCHH
VLKAELVMQKRGIYKYNCTATVDGKVATTAEIIVSHLRTEQA
HHHHHHHHHHCCCEEEECEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA