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The map label for this gene is yaeL [C]

Identifier: 50084555

GI number: 50084555

Start: 1372083

End: 1373438

Strand: Direct

Name: yaeL [C]

Synonym: ACIAD1377

Alternate gene names: 50084555

Gene position: 1372083-1373438 (Clockwise)

Preceding gene: 50084554

Following gene: 50084556

Centisome position: 38.13

GC content: 40.63

Gene sequence:

>1356_bases
ATGAATGTTTTATATATCGTCATCGCTGCAATTTTGCTGCTCGGACCTCTGATTGCAATTCATGAATTCGGTCATTATTG
GGTTGCCAGAAAACTAGGCGTAAAAGTCTTGGTTTATTCAATTGGTTTCGGTCCTACTTTACTGAAATGGACATCGAAAA
AATCAGGCATACAATATCAATTATCTGCTCTACCTTTGGGTGGTTATGTCAAGATGCTGGATGAGCGTGAGGGAAATGTA
GCCGAGGCTGATCTTCCTTATGCATTTAATCGACAGTCTCCCTGGAAACGTATTGCAATCGTGGCTGCGGGCCCATTGAT
TAATCTTTTTTTTGCAGTGTTTTTATTTTGGATACTTTTTTTGCCCACACAAGAGCAATTAAATACGCGTATAGGGAAAG
TTTTACCTGATACGGTAGCTGCGCAAGCAGGTTTGCAGGTGGGAGACAAAGTTACCTCGATTGATGGCAAAGAAACGCCA
ACATGGGAGCGTTTAAATTTTGCTTTAGTTGGTCGAGCTGGTGAGACTGGGAGTATTCAAGTTACTGTCGATCATCAGGG
GCAAGATAAAGCTGTTCAACTGCCAATTCATGATTTTTTAAAGAATCAGAGCCAATCGGCTCTTGATGTATTGGGATTTC
TACCGTATCGTCCTGCTATGCCAGCCGTCATTCATCAATTAAGTGAAGATGGTGCAGCAATTCGCCAGGGTATGAAAGTA
GGTGATCATATTTTGGCTGTAGATGGCGTAAAGATGAACGATTGGTTCGATGTCGTCGATATAGTGCAAAAATCACCTGA
GAAATTGCTTAATATAGATGTGTTGCGTAATGGTCAACTTGTTCATTTACAGGTTATGCCTCAAGGTAAACGGGATAATA
TGGGGAATGTGACAGGAATGCTTGGAGTACAAAGTAATCCAGGTAAAATGACTGTTCCAGCTGAATACAAGCAGCTAATC
CAATATAATCCGATTCAAGCTTTAGGAATGGCCACTGACAAGACAGTTCAAATTTCTGGTATGATATTGAATTCCATTGT
AAAAATGGTTCGTGGTTTGATTGGTTTGGAAAATTTATCTGGACCTATTACCATTGCGAAAGTCGCAGGTCAAAGTGCAG
AGATGGGGTGGCAAACATTTATTTCATTTATGGCTTTAATGAGTGTAAGCCTTGGGATTCTTAATTTGCTACCGATCCCG
ATGCTGGATGGAGGGCATTTGGTTTATTACTTTATCGAGGCCATTCGCGGTAAACCTGTTTCCGAACAAATACAGATGTT
CGGCTTAAAAATTGGTATGGTACTGCTCGGTAGCATGATGCTTTTAGCGCTTTTTAATGATTTTATGCGTCTATAA

Upstream 100 bases:

>100_bases
CAAAATGATACAGCAGTAAATATAGAGCAAGTTTTAGAAACCGATATGATTGCAAGACAGATTGCGCATCAATATGTAAA
TCAGATACGAGGCTAATGAG

Downstream 100 bases:

>100_bases
ACGCTGATATGGAAAAATTAACTTACTGGAAAAAACTGGCATGCGGCACACACATTTATTAATGCCTTTGGCACTTGTTA
GTGCTATGGCAGCGGTACAA

Product: membrane-associated Zn-dependent protease 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MNVLYIVIAAILLLGPLIAIHEFGHYWVARKLGVKVLVYSIGFGPTLLKWTSKKSGIQYQLSALPLGGYVKMLDEREGNV
AEADLPYAFNRQSPWKRIAIVAAGPLINLFFAVFLFWILFLPTQEQLNTRIGKVLPDTVAAQAGLQVGDKVTSIDGKETP
TWERLNFALVGRAGETGSIQVTVDHQGQDKAVQLPIHDFLKNQSQSALDVLGFLPYRPAMPAVIHQLSEDGAAIRQGMKV
GDHILAVDGVKMNDWFDVVDIVQKSPEKLLNIDVLRNGQLVHLQVMPQGKRDNMGNVTGMLGVQSNPGKMTVPAEYKQLI
QYNPIQALGMATDKTVQISGMILNSIVKMVRGLIGLENLSGPITIAKVAGQSAEMGWQTFISFMALMSVSLGILNLLPIP
MLDGGHLVYYFIEAIRGKPVSEQIQMFGLKIGMVLLGSMMLLALFNDFMRL

Sequences:

>Translated_451_residues
MNVLYIVIAAILLLGPLIAIHEFGHYWVARKLGVKVLVYSIGFGPTLLKWTSKKSGIQYQLSALPLGGYVKMLDEREGNV
AEADLPYAFNRQSPWKRIAIVAAGPLINLFFAVFLFWILFLPTQEQLNTRIGKVLPDTVAAQAGLQVGDKVTSIDGKETP
TWERLNFALVGRAGETGSIQVTVDHQGQDKAVQLPIHDFLKNQSQSALDVLGFLPYRPAMPAVIHQLSEDGAAIRQGMKV
GDHILAVDGVKMNDWFDVVDIVQKSPEKLLNIDVLRNGQLVHLQVMPQGKRDNMGNVTGMLGVQSNPGKMTVPAEYKQLI
QYNPIQALGMATDKTVQISGMILNSIVKMVRGLIGLENLSGPITIAKVAGQSAEMGWQTFISFMALMSVSLGILNLLPIP
MLDGGHLVYYFIEAIRGKPVSEQIQMFGLKIGMVLLGSMMLLALFNDFMRL
>Mature_451_residues
MNVLYIVIAAILLLGPLIAIHEFGHYWVARKLGVKVLVYSIGFGPTLLKWTSKKSGIQYQLSALPLGGYVKMLDEREGNV
AEADLPYAFNRQSPWKRIAIVAAGPLINLFFAVFLFWILFLPTQEQLNTRIGKVLPDTVAAQAGLQVGDKVTSIDGKETP
TWERLNFALVGRAGETGSIQVTVDHQGQDKAVQLPIHDFLKNQSQSALDVLGFLPYRPAMPAVIHQLSEDGAAIRQGMKV
GDHILAVDGVKMNDWFDVVDIVQKSPEKLLNIDVLRNGQLVHLQVMPQGKRDNMGNVTGMLGVQSNPGKMTVPAEYKQLI
QYNPIQALGMATDKTVQISGMILNSIVKMVRGLIGLENLSGPITIAKVAGQSAEMGWQTFISFMALMSVSLGILNLLPIP
MLDGGHLVYYFIEAIRGKPVSEQIQMFGLKIGMVLLGSMMLLALFNDFMRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=453, Percent_Identity=40.1766004415011, Blast_Score=325, Evalue=4e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49519; Mature: 49519

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLYIVIAAILLLGPLIAIHEFGHYWVARKLGVKVLVYSIGFGPTLLKWTSKKSGIQYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHEEECCCCCCCEEE
LSALPLGGYVKMLDEREGNVAEADLPYAFNRQSPWKRIAIVAAGPLINLFFAVFLFWILF
EEEECCCHHHHHHHCCCCCEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
LPTQEQLNTRIGKVLPDTVAAQAGLQVGDKVTSIDGKETPTWERLNFALVGRAGETGSIQ
CCCHHHHHHHHHHHCCHHHHHHCCCCCCCEEECCCCCCCCCHHHEEEEEEECCCCCCEEE
VTVDHQGQDKAVQLPIHDFLKNQSQSALDVLGFLPYRPAMPAVIHQLSEDGAAIRQGMKV
EEEECCCCCCEEECCHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHCCCC
GDHILAVDGVKMNDWFDVVDIVQKSPEKLLNIDVLRNGQLVHLQVMPQGKRDNMGNVTGM
CCEEEEECCEECCHHHHHHHHHHCCHHHHEEEEEECCCCEEEEEECCCCCCCCCCCEEEE
LGVQSNPGKMTVPAEYKQLIQYNPIQALGMATDKTVQISGMILNSIVKMVRGLIGLENLS
EEECCCCCCEECCHHHHHHHHCCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
GPITIAKVAGQSAEMGWQTFISFMALMSVSLGILNLLPIPMLDGGHLVYYFIEAIRGKPV
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCH
SEQIQMFGLKIGMVLLGSMMLLALFNDFMRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVLYIVIAAILLLGPLIAIHEFGHYWVARKLGVKVLVYSIGFGPTLLKWTSKKSGIQYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHEEECCCCCCCEEE
LSALPLGGYVKMLDEREGNVAEADLPYAFNRQSPWKRIAIVAAGPLINLFFAVFLFWILF
EEEECCCHHHHHHHCCCCCEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
LPTQEQLNTRIGKVLPDTVAAQAGLQVGDKVTSIDGKETPTWERLNFALVGRAGETGSIQ
CCCHHHHHHHHHHHCCHHHHHHCCCCCCCEEECCCCCCCCCHHHEEEEEEECCCCCCEEE
VTVDHQGQDKAVQLPIHDFLKNQSQSALDVLGFLPYRPAMPAVIHQLSEDGAAIRQGMKV
EEEECCCCCCEEECCHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHCCCC
GDHILAVDGVKMNDWFDVVDIVQKSPEKLLNIDVLRNGQLVHLQVMPQGKRDNMGNVTGM
CCEEEEECCEECCHHHHHHHHHHCCHHHHEEEEEECCCCEEEEEECCCCCCCCCCCEEEE
LGVQSNPGKMTVPAEYKQLIQYNPIQALGMATDKTVQISGMILNSIVKMVRGLIGLENLS
EEECCCCCCEECCHHHHHHHHCCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
GPITIAKVAGQSAEMGWQTFISFMALMSVSLGILNLLPIPMLDGGHLVYYFIEAIRGKPV
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCH
SEQIQMFGLKIGMVLLGSMMLLALFNDFMRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]