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The map label for this gene is argC

Identifier: 50084539

GI number: 50084539

Start: 1355781

End: 1356830

Strand: Direct

Name: argC

Synonym: ACIAD1360

Alternate gene names: 50084539

Gene position: 1355781-1356830 (Clockwise)

Preceding gene: 50084538

Following gene: 50084540

Centisome position: 37.68

GC content: 40.19

Gene sequence:

>1050_bases
GTGATTTCTGTCGGAATTGTTGGTGGAACTGGTTATACAGGCGTTGAGTTATTGCGCTTATTGCTTCGACATCCGCAAGT
TACGGTTCGTGTATTAACTTCTCGTACTGAAGCAGGAAAGCGCGTTGCAGATATGTTCCCGAGTTTAAGAGGGCATACTG
ACCTTGAGTTTTCAGATCTTAATGAAGATGTATTAAAGCAATGTGATGTTGTATTTTTTGCGACACCGCATGGTGTTGCG
ATGAAATATGCAAAAGGATTAGTCGCTGCCGGAGTGAAAGTGATTGATCTGGCGGCCGATTTTCGTCTTCAAAACTTAGA
GCAGTTTGAAAAATGGTATGGACTGGAGCATGAGTGTCCAGAGATACTTAAAGATTCAGTATATGGGTTGTCTGAACTTA
ATCGTGAAAAAATCAAGACAGCCAAAGTTGTTGGCAACCCAGGCTGTTACCCAACAACTGTCCAATTAGGTTTAGCACCT
TTACTACAAGCAGATGTGGCTTTAATCAAACCTGAAAATATTATTATTGATGCTAAGTCTGGAGTTTCTGGTGCGGGGCG
CAAAGCAAGTCTGGGTATGATTTACTCAGAAAATGCCGATAACTTTAAAGCTTATGGTGTGGCTGGTCATCGTCATCACC
CTGAAATTGTAGAAGCGCTTGAACATATTTCTGGACAAAAAGGTGTCTTTGATCAAATTATTTTTGTGCCTCATTTGGTG
CCTATGATTCGCGGCATGCTCAGTACAATTTATATCGATTTGACTGAAGAAGGTGCAAATAGTGATCTTCAATCTTTATA
TGAGATATATTACGCCAATGAAAAATTTGTAGATGTTATGCCTGCAAATAGCTCGCCAGAAACACGCAGTGTTCGTGGCG
CTAACGAGTTACGTATTGCGCTGTATAAACCACAACCAAATAAATTAGTTATCTTGTCTGTGCAAGATAATCTGGTGAAA
GGTGCAGCAGGTCAGGCCGTACAAAATATGAATCTCATGTTTAATCTTGATGAAGATACAGGATTAACGGGAATTGGTTT
ATTACCATAA

Upstream 100 bases:

>100_bases
AATATATAAAAAAATACTTTTAAGCCGAGAGAAATAGTTTTGAAAATTAGTACATCCTGTCATACTAGGCGCCATTCTGT
TGAACTTTGAGGTAAGACAC

Downstream 100 bases:

>100_bases
TGACGTTTTAAGACTTCACACACATTTCAATTTCGATTTAAATGTGTGTTGAGTTCTATCTTTAAATCGAGACGACGATG
CAAGACAATGAACACATGGC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MISVGIVGGTGYTGVELLRLLLRHPQVTVRVLTSRTEAGKRVADMFPSLRGHTDLEFSDLNEDVLKQCDVVFFATPHGVA
MKYAKGLVAAGVKVIDLAADFRLQNLEQFEKWYGLEHECPEILKDSVYGLSELNREKIKTAKVVGNPGCYPTTVQLGLAP
LLQADVALIKPENIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALEHISGQKGVFDQIIFVPHLV
PMIRGMLSTIYIDLTEEGANSDLQSLYEIYYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLVILSVQDNLVK
GAAGQAVQNMNLMFNLDEDTGLTGIGLLP

Sequences:

>Translated_349_residues
MISVGIVGGTGYTGVELLRLLLRHPQVTVRVLTSRTEAGKRVADMFPSLRGHTDLEFSDLNEDVLKQCDVVFFATPHGVA
MKYAKGLVAAGVKVIDLAADFRLQNLEQFEKWYGLEHECPEILKDSVYGLSELNREKIKTAKVVGNPGCYPTTVQLGLAP
LLQADVALIKPENIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALEHISGQKGVFDQIIFVPHLV
PMIRGMLSTIYIDLTEEGANSDLQSLYEIYYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLVILSVQDNLVK
GAAGQAVQNMNLMFNLDEDTGLTGIGLLP
>Mature_349_residues
MISVGIVGGTGYTGVELLRLLLRHPQVTVRVLTSRTEAGKRVADMFPSLRGHTDLEFSDLNEDVLKQCDVVFFATPHGVA
MKYAKGLVAAGVKVIDLAADFRLQNLEQFEKWYGLEHECPEILKDSVYGLSELNREKIKTAKVVGNPGCYPTTVQLGLAP
LLQADVALIKPENIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALEHISGQKGVFDQIIFVPHLV
PMIRGMLSTIYIDLTEEGANSDLQSLYEIYYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLVILSVQDNLVK
GAAGQAVQNMNLMFNLDEDTGLTGIGLLP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=348, Percent_Identity=37.0689655172414, Blast_Score=203, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320913, Length=346, Percent_Identity=28.9017341040462, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_ACIAD (Q6FCI4)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046049.1
- ProteinModelPortal:   Q6FCI4
- SMR:   Q6FCI4
- STRING:   Q6FCI4
- GeneID:   2877975
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1360
- NMPDR:   fig|62977.3.peg.593
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- PhylomeDB:   Q6FCI4
- ProtClustDB:   PRK00436
- BioCyc:   ASP62977:ACIAD1360-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38132; Mature: 38132

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVGIVGGTGYTGVELLRLLLRHPQVTVRVLTSRTEAGKRVADMFPSLRGHTDLEFSDL
CEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCHHCC
NEDVLKQCDVVFFATPHGVAMKYAKGLVAAGVKVIDLAADFRLQNLEQFEKWYGLEHECP
CHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCH
EILKDSVYGLSELNREKIKTAKVVGNPGCYPTTVQLGLAPLLQADVALIKPENIIIDAKS
HHHHHHHHCHHHHCHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCEEEECCCEEEEECCC
GVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALEHISGQKGVFDQIIFVPHLV
CCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
PMIRGMLSTIYIDLTEEGANSDLQSLYEIYYANEKFVDVMPANSSPETRSVRGANELRIA
HHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEE
LYKPQPNKLVILSVQDNLVKGAAGQAVQNMNLMFNLDEDTGLTGIGLLP
EECCCCCEEEEEEECCCHHCCCCCHHHHCCEEEEEECCCCCCCEECCCC
>Mature Secondary Structure
MISVGIVGGTGYTGVELLRLLLRHPQVTVRVLTSRTEAGKRVADMFPSLRGHTDLEFSDL
CEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCCHHCC
NEDVLKQCDVVFFATPHGVAMKYAKGLVAAGVKVIDLAADFRLQNLEQFEKWYGLEHECP
CHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCH
EILKDSVYGLSELNREKIKTAKVVGNPGCYPTTVQLGLAPLLQADVALIKPENIIIDAKS
HHHHHHHHCHHHHCHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCEEEECCCEEEEECCC
GVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALEHISGQKGVFDQIIFVPHLV
CCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
PMIRGMLSTIYIDLTEEGANSDLQSLYEIYYANEKFVDVMPANSSPETRSVRGANELRIA
HHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEE
LYKPQPNKLVILSVQDNLVKGAAGQAVQNMNLMFNLDEDTGLTGIGLLP
EECCCCCEEEEEEECCCHHCCCCCHHHHCCEEEEEECCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA