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The map label for this gene is rpiA

Identifier: 50084537

GI number: 50084537

Start: 1354274

End: 1354945

Strand: Direct

Name: rpiA

Synonym: ACIAD1358

Alternate gene names: 50084537

Gene position: 1354274-1354945 (Clockwise)

Preceding gene: 50084533

Following gene: 50084538

Centisome position: 37.63

GC content: 42.41

Gene sequence:

>672_bases
ATGAGTCTATATGCTACCCAAGATGAGAAAAAACAAGCAGCGGCAAAAGCTGCTTTAAAACACTTACCAAAAGGGGGGAT
TTTGGGGGTAGGAACAGGAAGTACCGTCAATTTTCTGATTGAACTTTTACCTGAATTACAGCTTGAAGCGGCGGTTGCTA
GCTCGGAAGCAACAGCTAAACGCCTAAAAGAATTGGGTATCGAAGTGGTTGATATGAACCATGTGGGTGGATTGGATGCT
TATGTCGATGGTGCAGATGAAATTGACCGTCATATGCATATGATTAAAGGGGGGGGGGCGGCACTCACACGTGAAAAAAT
TGTGGCATCGATTGCAAAGAAATTTGTGTGTATTGTTGATGATTCAAAATGGGTAGAGCAGTTAGGTCGCGATTTTCCAT
TGCCAGTTGAAGTGATTCCAATGGCGCGTTCTGCTGTTGCACGCAAACTTGTGAGTTTAGGTGGAGATCCCGTATATCGC
GAAGGCGTGGTTACAGACAACGGAAACGTAATTTTAGACGTTTATAACCTGAATATTTTAAACGCACTTGAGCTTGAAAA
AACCATTAATGATATTCCTGGTGTAGTGACCAATGGTATTTTTGCATTAAACGCAGCATCCATTGCCATTGTTGCGACCA
ATAATGGTATTGAAGAGCGTACAGCAGTTTAA

Upstream 100 bases:

>100_bases
TTTTCCATGTAACAGTTTAAAATAGCCACTTATTGTAACAAACCCCTGCACCTTTGCGTTTTAAAATTGCGCAAAATGTG
AAAAAAAGTTGAGTGATGTC

Downstream 100 bases:

>100_bases
TGATCTCAGAATTACCTGAAATCAAAATTGTTAGACACGTAAATGCAAAATGCTTGCGTTTACGTGTTGAACCTCATGCT
ATTAGATTAACTGTACCTAC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSLYATQDEKKQAAAKAALKHLPKGGILGVGTGSTVNFLIELLPELQLEAAVASSEATAKRLKELGIEVVDMNHVGGLDA
YVDGADEIDRHMHMIKGGGAALTREKIVASIAKKFVCIVDDSKWVEQLGRDFPLPVEVIPMARSAVARKLVSLGGDPVYR
EGVVTDNGNVILDVYNLNILNALELEKTINDIPGVVTNGIFALNAASIAIVATNNGIEERTAV

Sequences:

>Translated_223_residues
MSLYATQDEKKQAAAKAALKHLPKGGILGVGTGSTVNFLIELLPELQLEAAVASSEATAKRLKELGIEVVDMNHVGGLDA
YVDGADEIDRHMHMIKGGGAALTREKIVASIAKKFVCIVDDSKWVEQLGRDFPLPVEVIPMARSAVARKLVSLGGDPVYR
EGVVTDNGNVILDVYNLNILNALELEKTINDIPGVVTNGIFALNAASIAIVATNNGIEERTAV
>Mature_222_residues
SLYATQDEKKQAAAKAALKHLPKGGILGVGTGSTVNFLIELLPELQLEAAVASSEATAKRLKELGIEVVDMNHVGGLDAY
VDGADEIDRHMHMIKGGGAALTREKIVASIAKKFVCIVDDSKWVEQLGRDFPLPVEVIPMARSAVARKLVSLGGDPVYRE
GVVTDNGNVILDVYNLNILNALELEKTINDIPGVVTNGIFALNAASIAIVATNNGIEERTAV

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=215, Percent_Identity=34.4186046511628, Blast_Score=107, Evalue=7e-24,
Organism=Escherichia coli, GI1789280, Length=215, Percent_Identity=60.4651162790698, Blast_Score=253, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17551758, Length=234, Percent_Identity=33.7606837606838, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6324669, Length=236, Percent_Identity=29.6610169491525, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364072, Length=213, Percent_Identity=33.8028169014084, Blast_Score=101, Evalue=4e-22,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_ACIAD (Q6FCI6)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046047.1
- ProteinModelPortal:   Q6FCI6
- SMR:   Q6FCI6
- STRING:   Q6FCI6
- GeneID:   2879518
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1358
- NMPDR:   fig|62977.3.peg.591
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- PhylomeDB:   Q6FCI6
- ProtClustDB:   PRK00702
- BioCyc:   ASP62977:ACIAD1358-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23682; Mature: 23550

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLYATQDEKKQAAAKAALKHLPKGGILGVGTGSTVNFLIELLPELQLEAAVASSEATAK
CCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
RLKELGIEVVDMNHVGGLDAYVDGADEIDRHMHMIKGGGAALTREKIVASIAKKFVCIVD
HHHHCCCEEEEECCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEC
DSKWVEQLGRDFPLPVEVIPMARSAVARKLVSLGGDPVYREGVVTDNGNVILDVYNLNIL
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEECCCCH
NALELEKTINDIPGVVTNGIFALNAASIAIVATNNGIEERTAV
HHHHHHHHHHHCCHHHHCCEEEEECCEEEEEEECCCCHHHCCC
>Mature Secondary Structure 
SLYATQDEKKQAAAKAALKHLPKGGILGVGTGSTVNFLIELLPELQLEAAVASSEATAK
CCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
RLKELGIEVVDMNHVGGLDAYVDGADEIDRHMHMIKGGGAALTREKIVASIAKKFVCIVD
HHHHCCCEEEEECCCCCCHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEC
DSKWVEQLGRDFPLPVEVIPMARSAVARKLVSLGGDPVYREGVVTDNGNVILDVYNLNIL
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEECCCCH
NALELEKTINDIPGVVTNGIFALNAASIAIVATNNGIEERTAV
HHHHHHHHHHHCCHHHHCCEEEEECCEEEEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA