Click here to switch to the map view.

The map label for this gene is lrp [H]

Identifier: 50084524

GI number: 50084524

Start: 1339416

End: 1339907

Strand: Direct

Name: lrp [H]

Synonym: ACIAD1344

Alternate gene names: 50084524

Gene position: 1339416-1339907 (Clockwise)

Preceding gene: 50084523

Following gene: 50084525

Centisome position: 37.22

GC content: 35.37

Gene sequence:

>492_bases
ATGAGTCAAGGTTTGGATGATTACGATTATAAAATCTTACGGCATTTGCAAAGCAATGGGCGTTTGAGTAATCAGGAACT
TTCAGAGATTATTGGTTTATCAACATCACAATGTTCGCGTCGTCGGATTGCACTTGAGCAAAAGGGCATGATTATTGGTT
ATTTTGCGCAGGTTCATCCACAAGCAGAGAAACAACCCATTATGGGGATGATCGAGATTAAATTACAGCATTATAGTTTG
GAAACTTTAGAAAAATTTTTGGATTTTGTGAAAAATGAATCAATGATTCGTGAGGTGTATAAGCTGACGGGAAGTTATGA
CTATGTACTCAAAGTGACGGTAGAAGATTTGAATCAGATGAGTCAGTTAATCAATCAGTTAATGTCACTCAATATTAGTA
TTGGGAACTTTAATACCTCTATTGTATTAGAGCGTATTAAAGAAAATCATCAGATGATGAATACAGGAAAGTCAAATGAC
ACACATGGCTAA

Upstream 100 bases:

>100_bases
ATTCTTTATATTTTTTATCGTTTTAAGGCACCAGCCAGTAAGATGACTGAGTCTGTATTGGATCAATAAATCACTGATCA
GTTAATTTGAGGTAGTTTAA

Downstream 100 bases:

>100_bases
ACCCAATGATTTTCTAGTGACTATTCCTAAAAAATCGCATTCATCGATTGAAGATATGCTGGCGATGGTCATTGCGACCT
TTATTATTTCATTTGGCATG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MSQGLDDYDYKILRHLQSNGRLSNQELSEIIGLSTSQCSRRRIALEQKGMIIGYFAQVHPQAEKQPIMGMIEIKLQHYSL
ETLEKFLDFVKNESMIREVYKLTGSYDYVLKVTVEDLNQMSQLINQLMSLNISIGNFNTSIVLERIKENHQMMNTGKSND
THG

Sequences:

>Translated_163_residues
MSQGLDDYDYKILRHLQSNGRLSNQELSEIIGLSTSQCSRRRIALEQKGMIIGYFAQVHPQAEKQPIMGMIEIKLQHYSL
ETLEKFLDFVKNESMIREVYKLTGSYDYVLKVTVEDLNQMSQLINQLMSLNISIGNFNTSIVLERIKENHQMMNTGKSND
THG
>Mature_162_residues
SQGLDDYDYKILRHLQSNGRLSNQELSEIIGLSTSQCSRRRIALEQKGMIIGYFAQVHPQAEKQPIMGMIEIKLQHYSLE
TLEKFLDFVKNESMIREVYKLTGSYDYVLKVTVEDLNQMSQLINQLMSLNISIGNFNTSIVLERIKENHQMMNTGKSNDT
HG

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=151, Percent_Identity=31.1258278145695, Blast_Score=87, Evalue=5e-19,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=30.0699300699301, Blast_Score=80, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18790; Mature: 18659

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQGLDDYDYKILRHLQSNGRLSNQELSEIIGLSTSQCSRRRIALEQKGMIIGYFAQVHP
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEHHHHCC
QAEKQPIMGMIEIKLQHYSLETLEKFLDFVKNESMIREVYKLTGSYDYVLKVTVEDLNQM
CCCCCCCCCCEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEHHHHHHH
SQLINQLMSLNISIGNFNTSIVLERIKENHQMMNTGKSNDTHG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SQGLDDYDYKILRHLQSNGRLSNQELSEIIGLSTSQCSRRRIALEQKGMIIGYFAQVHP
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEHHHHCC
QAEKQPIMGMIEIKLQHYSLETLEKFLDFVKNESMIREVYKLTGSYDYVLKVTVEDLNQM
CCCCCCCCCCEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEHHHHHHH
SQLINQLMSLNISIGNFNTSIVLERIKENHQMMNTGKSNDTHG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]