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The map label for this gene is gcp

Identifier: 50084513

GI number: 50084513

Start: 1328767

End: 1329789

Strand: Direct

Name: gcp

Synonym: ACIAD1332

Alternate gene names: 50084513

Gene position: 1328767-1329789 (Clockwise)

Preceding gene: 50084510

Following gene: 50084516

Centisome position: 36.92

GC content: 44.48

Gene sequence:

>1023_bases
ATGATTGTTTTGGGTCTTGAAACATCGTGTGATGAAACAGGTCTGGCGCTTTATGACAGTGAAAAGGGCTTGCTCGGACA
AGTACTCTACAGTCAGATTAAACTGCATGCTGAATATGGTGGTGTAGTTCCCGAGCTTGCGTCTCGTGATCATGTCAGAA
AAATGATTCCACTTCTTGATCAGCTTTTAAACGACAGCCAAGTAAAAAAATCTCAGATTGATGCAGTGGCGTACACGCGC
GGGCCTGGTCTGATGGGCGCCCTCATGACAGGTGCTTTATTTGGCCGAACTCTGGCATTTGCACTCAATAAACCTGCCAT
TGGTGTTCATCATATGGAAGGTCACATGCTTGCACCGCTACTTTCTGCAACGCCACCAGAATTTCCATTTGTTGCCTTAT
TGGTATCGGGTGGTCACACTCAACTCATGGCTGCTTATGGTATCGGTCAATATGAGTTGCTTGGTGAGTCTATTGATGAT
GCTGCGGGTGAGGCATTCGATAAAGTCGCTAAAATGATGGGATTACCTTATCCGGGTGGACCAAATATTGCAAAATTAGC
TTTGCAGGGGAACCCAGAAACATTTGAATTTCCTCGCCCCATGCTTCATCAAGGCTTAGACTTTTCTTTTAGCGGCCTAA
AAACGTCAGTTTCTGTTCAGCTCAAAAAATTGGGTGAAGAAAATCGTGATGCTGATATTGCGGCTTCTTTCCAAGAGGCG
ATTGTCGATACATTGGTGAAGAAATCTGTGAAGGCTTTAAAGCAGACAGGTTTAAAACGTCTAGTGATTGCGGGTGGTGT
GAGTGCCAATCAGCGATTACGTGAGCGCCTTGAGCATTCATTATCAAAAATCAAGTCACAAGTTTATTATGCTGAACCTG
CATTATGTACAGATAATGGTGCAATGATTGCATTTGCAGGCTATCAACGTTTAAAGGCTGGGCAATGTGATGATTTGGTG
GTCACTACCACACCGCGCTGGCCAATGACTGAATTGAGTCGTCCAGCAGAGATAATCGAATAA

Upstream 100 bases:

>100_bases
TAGATGACAAGTGAAGGTCAGTATTTTACTCATTTACAACTGATATCACAAGTCTATAATAGCGTTGACACAATTTTAGT
AGCATCAAATAGGCGGTTGA

Downstream 100 bases:

>100_bases
ATCAAAACATGTTTGACGAAGTTGATCCACAGCTTCGTCAGGATTGATTTAATGTATGATTGTCGATGATGTCTGTGTGC
TTGGTGGAGTTAGAAGGCCT

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MIVLGLETSCDETGLALYDSEKGLLGQVLYSQIKLHAEYGGVVPELASRDHVRKMIPLLDQLLNDSQVKKSQIDAVAYTR
GPGLMGALMTGALFGRTLAFALNKPAIGVHHMEGHMLAPLLSATPPEFPFVALLVSGGHTQLMAAYGIGQYELLGESIDD
AAGEAFDKVAKMMGLPYPGGPNIAKLALQGNPETFEFPRPMLHQGLDFSFSGLKTSVSVQLKKLGEENRDADIAASFQEA
IVDTLVKKSVKALKQTGLKRLVIAGGVSANQRLRERLEHSLSKIKSQVYYAEPALCTDNGAMIAFAGYQRLKAGQCDDLV
VTTTPRWPMTELSRPAEIIE

Sequences:

>Translated_340_residues
MIVLGLETSCDETGLALYDSEKGLLGQVLYSQIKLHAEYGGVVPELASRDHVRKMIPLLDQLLNDSQVKKSQIDAVAYTR
GPGLMGALMTGALFGRTLAFALNKPAIGVHHMEGHMLAPLLSATPPEFPFVALLVSGGHTQLMAAYGIGQYELLGESIDD
AAGEAFDKVAKMMGLPYPGGPNIAKLALQGNPETFEFPRPMLHQGLDFSFSGLKTSVSVQLKKLGEENRDADIAASFQEA
IVDTLVKKSVKALKQTGLKRLVIAGGVSANQRLRERLEHSLSKIKSQVYYAEPALCTDNGAMIAFAGYQRLKAGQCDDLV
VTTTPRWPMTELSRPAEIIE
>Mature_340_residues
MIVLGLETSCDETGLALYDSEKGLLGQVLYSQIKLHAEYGGVVPELASRDHVRKMIPLLDQLLNDSQVKKSQIDAVAYTR
GPGLMGALMTGALFGRTLAFALNKPAIGVHHMEGHMLAPLLSATPPEFPFVALLVSGGHTQLMAAYGIGQYELLGESIDD
AAGEAFDKVAKMMGLPYPGGPNIAKLALQGNPETFEFPRPMLHQGLDFSFSGLKTSVSVQLKKLGEENRDADIAASFQEA
IVDTLVKKSVKALKQTGLKRLVIAGGVSANQRLRERLEHSLSKIKSQVYYAEPALCTDNGAMIAFAGYQRLKAGQCDDLV
VTTTPRWPMTELSRPAEIIE

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=338, Percent_Identity=38.1656804733728, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI8923380, Length=323, Percent_Identity=32.8173374613003, Blast_Score=152, Evalue=6e-37,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=64.0718562874251, Blast_Score=437, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI71995670, Length=332, Percent_Identity=32.8313253012048, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17557464, Length=328, Percent_Identity=31.7073170731707, Blast_Score=137, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6320099, Length=366, Percent_Identity=34.1530054644809, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6322891, Length=351, Percent_Identity=28.4900284900285, Blast_Score=132, Evalue=8e-32,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=33.8235294117647, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI21357207, Length=327, Percent_Identity=32.7217125382263, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_ACIAD (Q6FCK9)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046023.1
- ProteinModelPortal:   Q6FCK9
- SMR:   Q6FCK9
- STRING:   Q6FCK9
- MEROPS:   M22.001
- GeneID:   2879625
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1332
- NMPDR:   fig|62977.3.peg.505
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q6FCK9
- ProtClustDB:   PRK09604
- BioCyc:   ASP62977:ACIAD1332-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36724; Mature: 36724

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLGLETSCDETGLALYDSEKGLLGQVLYSQIKLHAEYGGVVPELASRDHVRKMIPLLD
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QLLNDSQVKKSQIDAVAYTRGPGLMGALMTGALFGRTLAFALNKPAIGVHHMEGHMLAPL
HHHCCHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
LSATPPEFPFVALLVSGGHTQLMAAYGIGQYELLGESIDDAAGEAFDKVAKMMGLPYPGG
HHCCCCCCCEEEEEECCCCCEEHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PNIAKLALQGNPETFEFPRPMLHQGLDFSFSGLKTSVSVQLKKLGEENRDADIAASFQEA
CCEEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
IVDTLVKKSVKALKQTGLKRLVIAGGVSANQRLRERLEHSLSKIKSQVYYAEPALCTDNG
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEECCCCEECCCC
AMIAFAGYQRLKAGQCDDLVVTTTPRWPMTELSRPAEIIE
CEEEEECHHHHCCCCCCCEEEECCCCCCHHHHCCCHHHCC
>Mature Secondary Structure
MIVLGLETSCDETGLALYDSEKGLLGQVLYSQIKLHAEYGGVVPELASRDHVRKMIPLLD
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QLLNDSQVKKSQIDAVAYTRGPGLMGALMTGALFGRTLAFALNKPAIGVHHMEGHMLAPL
HHHCCHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHH
LSATPPEFPFVALLVSGGHTQLMAAYGIGQYELLGESIDDAAGEAFDKVAKMMGLPYPGG
HHCCCCCCCEEEEEECCCCCEEHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PNIAKLALQGNPETFEFPRPMLHQGLDFSFSGLKTSVSVQLKKLGEENRDADIAASFQEA
CCEEEEEECCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
IVDTLVKKSVKALKQTGLKRLVIAGGVSANQRLRERLEHSLSKIKSQVYYAEPALCTDNG
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEECCCCEECCCC
AMIAFAGYQRLKAGQCDDLVVTTTPRWPMTELSRPAEIIE
CEEEEECHHHHCCCCCCCEEEECCCCCCHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA