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The map label for this gene is speB [H]

Identifier: 50084482

GI number: 50084482

Start: 1301544

End: 1302503

Strand: Direct

Name: speB [H]

Synonym: ACIAD1299

Alternate gene names: 50084482

Gene position: 1301544-1302503 (Clockwise)

Preceding gene: 50084481

Following gene: 50084483

Centisome position: 36.17

GC content: 45.21

Gene sequence:

>960_bases
ATGGCCAAAAATTTACATCAACCTCTTGGTGGAAACGAAATGCCGCGTTTTGGTGGTATCGCATCCATGATGCGTTTACC
CGTTATTGAAACGCCTGAGGAGTTGGCTAAATTGGATGCTGCATTTGTGGGTATTCCTTTGGATATTGGAACGTCCCTTA
GATCTGGAACACGCTTTGGACCGCGTCAGATTCGCGCAGAATCCGTCATGATCAGACCGTATAACATGGCAACCGGCGCG
GCACCGTTTGATTGTATTAATGTGGCGGATATTGGTGATATTGCAATCAATACATTTAACTTACTGCATGCTGTTGAAAT
TATTGAACAAGAATATGACCGCATTTTGTCATATGGAATTATTCCCTTAACACTGGGTGGCGACCATACTTTAACATTAC
CGATTCTACGGGCACTTAAGAAAAAACATGGCAAAGTCGGTTTGGTACATATCGATGCCCATGCAGACGTCAATGACCAC
ATGTTTGGTGAAAAAATTGCGCATGGAACCACCTTTCGCCGCGCAGTAGAAGAAGATCTTCTGGATTGTGATCGTGTCGT
ACAGATTGGCCTAAGAGCACAGGGTTATAGTGCCGATGACTTTAACTGGAGTCGTCGTCAGGGATTTAGGGTGGTACAGG
CGGAAGAATGCTGGCATCAATCTTTAGCGCCACTCATGGCTGAAGTCAGAGAAAAAGTAGGTGGCGGGCCTGTTTATTTA
TCTTTCGATATCGATGGGATCGATCCTGCTTGGGCACCAGGCACAGGAACGCCAGAGATTGGTGGGCTGACTACTATTCA
AGCGCTGGAAATTATTCGTGGATGTGAGGGGCTGGATATTATAGGTGGCGATTTGGTCGAGGTTTCTCCACCTTATGACA
CTACAGGAAATACCTCCTTGCTCGGTGCCAATCTCTTGTTTGAAATGTTATGTATTTTGCCAAATGTCATGAAGAAATAA

Upstream 100 bases:

>100_bases
TTAGTTTATAAATATCAAAACTAATTATTTAATAAATACTATTTAAGCTAAGGTGTTTTTATTAGATAAATAATGAAAAC
AAACAGATATAGGTATACAA

Downstream 100 bases:

>100_bases
AGTTTTTAGCGAGTTACATAGGTAAATATCAATGACCTTACTTTAAAAGCATGGTAGAGGAAGACATATTTTCTATGATG
AAAATTGATTGTAGTTAAGG

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAKNLHQPLGGNEMPRFGGIASMMRLPVIETPEELAKLDAAFVGIPLDIGTSLRSGTRFGPRQIRAESVMIRPYNMATGA
APFDCINVADIGDIAINTFNLLHAVEIIEQEYDRILSYGIIPLTLGGDHTLTLPILRALKKKHGKVGLVHIDAHADVNDH
MFGEKIAHGTTFRRAVEEDLLDCDRVVQIGLRAQGYSADDFNWSRRQGFRVVQAEECWHQSLAPLMAEVREKVGGGPVYL
SFDIDGIDPAWAPGTGTPEIGGLTTIQALEIIRGCEGLDIIGGDLVEVSPPYDTTGNTSLLGANLLFEMLCILPNVMKK

Sequences:

>Translated_319_residues
MAKNLHQPLGGNEMPRFGGIASMMRLPVIETPEELAKLDAAFVGIPLDIGTSLRSGTRFGPRQIRAESVMIRPYNMATGA
APFDCINVADIGDIAINTFNLLHAVEIIEQEYDRILSYGIIPLTLGGDHTLTLPILRALKKKHGKVGLVHIDAHADVNDH
MFGEKIAHGTTFRRAVEEDLLDCDRVVQIGLRAQGYSADDFNWSRRQGFRVVQAEECWHQSLAPLMAEVREKVGGGPVYL
SFDIDGIDPAWAPGTGTPEIGGLTTIQALEIIRGCEGLDIIGGDLVEVSPPYDTTGNTSLLGANLLFEMLCILPNVMKK
>Mature_318_residues
AKNLHQPLGGNEMPRFGGIASMMRLPVIETPEELAKLDAAFVGIPLDIGTSLRSGTRFGPRQIRAESVMIRPYNMATGAA
PFDCINVADIGDIAINTFNLLHAVEIIEQEYDRILSYGIIPLTLGGDHTLTLPILRALKKKHGKVGLVHIDAHADVNDHM
FGEKIAHGTTFRRAVEEDLLDCDRVVQIGLRAQGYSADDFNWSRRQGFRVVQAEECWHQSLAPLMAEVREKVGGGPVYLS
FDIDGIDPAWAPGTGTPEIGGLTTIQALEIIRGCEGLDIIGGDLVEVSPPYDTTGNTSLLGANLLFEMLCILPNVMKK

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=311, Percent_Identity=60.4501607717042, Blast_Score=396, Evalue=1e-110,
Organism=Homo sapiens, GI10947139, Length=275, Percent_Identity=24.7272727272727, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789306, Length=299, Percent_Identity=39.4648829431438, Blast_Score=185, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 34736; Mature: 34605

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNLHQPLGGNEMPRFGGIASMMRLPVIETPEELAKLDAAFVGIPLDIGTSLRSGTRFG
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHEECCHHCCCCCCCCCCCC
PRQIRAESVMIRPYNMATGAAPFDCINVADIGDIAINTFNLLHAVEIIEQEYDRILSYGI
HHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPLTLGGDHTLTLPILRALKKKHGKVGLVHIDAHADVNDHMFGEKIAHGTTFRRAVEEDL
EEEEECCCCEEHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHH
LDCDRVVQIGLRAQGYSADDFNWSRRQGFRVVQAEECWHQSLAPLMAEVREKVGGGPVYL
HHHHHHHHHCCCCCCCCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEE
SFDIDGIDPAWAPGTGTPEIGGLTTIQALEIIRGCEGLDIIGGDLVEVSPPYDTTGNTSL
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCEEEECCCCCCCCCCHH
LGANLLFEMLCILPNVMKK
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKNLHQPLGGNEMPRFGGIASMMRLPVIETPEELAKLDAAFVGIPLDIGTSLRSGTRFG
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHEECCHHCCCCCCCCCCCC
PRQIRAESVMIRPYNMATGAAPFDCINVADIGDIAINTFNLLHAVEIIEQEYDRILSYGI
HHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPLTLGGDHTLTLPILRALKKKHGKVGLVHIDAHADVNDHMFGEKIAHGTTFRRAVEEDL
EEEEECCCCEEHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHH
LDCDRVVQIGLRAQGYSADDFNWSRRQGFRVVQAEECWHQSLAPLMAEVREKVGGGPVYL
HHHHHHHHHCCCCCCCCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEE
SFDIDGIDPAWAPGTGTPEIGGLTTIQALEIIRGCEGLDIIGGDLVEVSPPYDTTGNTSL
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCEEEECCCCCCCCCCHH
LGANLLFEMLCILPNVMKK
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA