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The map label for this gene is lysM [H]

Identifier: 50084468

GI number: 50084468

Start: 1285563

End: 1285985

Strand: Reverse

Name: lysM [H]

Synonym: ACIAD1283

Alternate gene names: 50084468

Gene position: 1285985-1285563 (Counterclockwise)

Preceding gene: 50084474

Following gene: 50084454

Centisome position: 35.74

GC content: 39.95

Gene sequence:

>423_bases
ATGAATGATACAGATAGCCAAATTTTGGGTTTACTACGAGATAATGCACGCATGTCGGTGACTGATCTGGCAGCCAAGGT
CAAAGTATCACGGGCAACGATTCAGAAGCGAATCGAATACATGGAGAATCAAGGCATTATTACTGGCTATACCGTCAGAA
TAAAACCGAATTCTGAACAAAACATGATTCGTGCCTGGATGAATATTATGGTAGAGGGAAATAAAGCCAGTGCGGTGATT
CGAGAATTGAGAATTGACCCTGCTGTGCATACGCTGCATACCACCAATGGCAAATGGGATCTTCTGGTTGAATTAAAATC
TGAAAATTTGGCGAGTTTTGACAAGATATTAGAGAGAATCCGAACCATTAACGGAATTTATAATACTGAAACAAGTATTT
TACTATCGACCTATAAGGCGTGA

Upstream 100 bases:

>100_bases
TTGATATTGACTAGTATGAAAAATCAATTTGATTTAAAAAAGTTGTTATTATGATTAAATTGATACAATATTAGACACAT
TGAATAGCGATTAAATCAAA

Downstream 100 bases:

>100_bases
TTTGGTCTATATGACTTTCAGAAATTGATGAAGTATCAATCAATTGAATTTAAATAGCATACTTGGTTACGCAACTGAAA
TGTTAAAAGATCACGACCAG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNDTDSQILGLLRDNARMSVTDLAAKVKVSRATIQKRIEYMENQGIITGYTVRIKPNSEQNMIRAWMNIMVEGNKASAVI
RELRIDPAVHTLHTTNGKWDLLVELKSENLASFDKILERIRTINGIYNTETSILLSTYKA

Sequences:

>Translated_140_residues
MNDTDSQILGLLRDNARMSVTDLAAKVKVSRATIQKRIEYMENQGIITGYTVRIKPNSEQNMIRAWMNIMVEGNKASAVI
RELRIDPAVHTLHTTNGKWDLLVELKSENLASFDKILERIRTINGIYNTETSILLSTYKA
>Mature_140_residues
MNDTDSQILGLLRDNARMSVTDLAAKVKVSRATIQKRIEYMENQGIITGYTVRIKPNSEQNMIRAWMNIMVEGNKASAVI
RELRIDPAVHTLHTTNGKWDLLVELKSENLASFDKILERIRTINGIYNTETSILLSTYKA

Specific function: In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the diaminopimelate pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790182, Length=138, Percent_Identity=28.9855072463768, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 15909; Mature: 15909

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTDSQILGLLRDNARMSVTDLAAKVKVSRATIQKRIEYMENQGIITGYTVRIKPNSEQ
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHH
NMIRAWMNIMVEGNKASAVIRELRIDPAVHTLHTTNGKWDLLVELKSENLASFDKILERI
HHHHHHHHHEECCCHHHHHHHHHHCCCHHEEEECCCCCEEEEEEECCCCHHHHHHHHHHH
RTINGIYNTETSILLSTYKA
HHHCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MNDTDSQILGLLRDNARMSVTDLAAKVKVSRATIQKRIEYMENQGIITGYTVRIKPNSEQ
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHH
NMIRAWMNIMVEGNKASAVIRELRIDPAVHTLHTTNGKWDLLVELKSENLASFDKILERI
HHHHHHHHHEECCCHHHHHHHHHHCCCHHEEEECCCCCEEEEEEECCCCHHHHHHHHHHH
RTINGIYNTETSILLSTYKA
HHHCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726; 12042311 [H]