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The map label for this gene is yggG [H]

Identifier: 50084446

GI number: 50084446

Start: 1258605

End: 1259384

Strand: Direct

Name: yggG [H]

Synonym: ACIAD1260

Alternate gene names: 50084446

Gene position: 1258605-1259384 (Clockwise)

Preceding gene: 50084445

Following gene: 50084449

Centisome position: 34.97

GC content: 43.21

Gene sequence:

>780_bases
ATGAATAAAAAAATTGTGATGAGTTTTTTGGCTGCTACGGTAGTTACTATTTCAGGTTGTGCTTCTTTTGCTGATATGGC
AGGTGCCGATTCCGCCACCTTAAATGCTTCAGCAGCACAAGGCTTTAGTAAAATGACCACGGAAGCAAGACAAAAAGGAC
AGTTGGATACTTCATCTAATACTTATCGTCGTATTAATACCGTGATGCAGCGTATGATCCCATACGCAAATCAGATGAAC
CAGACGGGTCAGCCGTTCCAGTGGCAGCTTGCAGTGATTAAATCTGATACGGTCAATGCCTATGTTGCTCCAGGTGGTAA
GGTCGTCTTCTATACAGGTATTGTAAACAAATTAAACCTGAGTGATGCTGAGATTGCTGCTGTTATGGGGCATGAGATGA
CCCATGCGCTTGAAGAACATGCTAAGAGTAAAATCGGAGCAGAAGCGCTTACAGGTTTAGCTTTAAATATTGGTAAAGCT
TACGCTGGTGATAGTATTGGACAGGCTGGATCGGCTGCACTGGATTTAGGTAGTCAGGTAGGTGTAGGCTTACCTTATTC
TCGTAATCTGGAAAGCCGTGCCGATTATGGTGGTTTAATGTTGATGGCTAAAGCAGGGTACAACCCGCAAGCAGCGATTA
CACTTTGGGAAAAAATGAATCGAATGGATGGAGCTGGTGGGCCATCATTCCTTTCAACACACCCATCGAATAACCAGCGT
ATTCAAGATATGAGAAAAAATTTACCAGCAGCAATGGCTGTTTATAATAATCGCCGTTAA

Upstream 100 bases:

>100_bases
TAAATGCTATGATGTTTTCTCAATTATCCGATATGTTTTACTTATAATGCACTGCAAAACAGAGACATAGATTAGTTATG
TCGGATCGTGGAGTAATTGA

Downstream 100 bases:

>100_bases
GTTTGGTGCTTTAGTAAGAAACACAGGATGTCTTATGACATCCTGTATTCATTTTAAGGTGCTGGATTTGGTTGTTGTTT
ATGTATATCTTCAATACCCT

Product: Zn-dependent protease with chaperone function

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNKKIVMSFLAATVVTISGCASFADMAGADSATLNASAAQGFSKMTTEARQKGQLDTSSNTYRRINTVMQRMIPYANQMN
QTGQPFQWQLAVIKSDTVNAYVAPGGKVVFYTGIVNKLNLSDAEIAAVMGHEMTHALEEHAKSKIGAEALTGLALNIGKA
YAGDSIGQAGSAALDLGSQVGVGLPYSRNLESRADYGGLMLMAKAGYNPQAAITLWEKMNRMDGAGGPSFLSTHPSNNQR
IQDMRKNLPAAMAVYNNRR

Sequences:

>Translated_259_residues
MNKKIVMSFLAATVVTISGCASFADMAGADSATLNASAAQGFSKMTTEARQKGQLDTSSNTYRRINTVMQRMIPYANQMN
QTGQPFQWQLAVIKSDTVNAYVAPGGKVVFYTGIVNKLNLSDAEIAAVMGHEMTHALEEHAKSKIGAEALTGLALNIGKA
YAGDSIGQAGSAALDLGSQVGVGLPYSRNLESRADYGGLMLMAKAGYNPQAAITLWEKMNRMDGAGGPSFLSTHPSNNQR
IQDMRKNLPAAMAVYNNRR
>Mature_259_residues
MNKKIVMSFLAATVVTISGCASFADMAGADSATLNASAAQGFSKMTTEARQKGQLDTSSNTYRRINTVMQRMIPYANQMN
QTGQPFQWQLAVIKSDTVNAYVAPGGKVVFYTGIVNKLNLSDAEIAAVMGHEMTHALEEHAKSKIGAEALTGLALNIGKA
YAGDSIGQAGSAALDLGSQVGVGLPYSRNLESRADYGGLMLMAKAGYNPQAAITLWEKMNRMDGAGGPSFLSTHPSNNQR
IQDMRKNLPAAMAVYNNRR

Specific function: Seems to regulate the expression of speB [H]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=192, Percent_Identity=29.6875, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI87082185, Length=259, Percent_Identity=27.7992277992278, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788840, Length=192, Percent_Identity=28.6458333333333, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081800, Length=267, Percent_Identity=23.9700374531835, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322940, Length=181, Percent_Identity=35.3591160220994, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 27621; Mature: 27621

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKIVMSFLAATVVTISGCASFADMAGADSATLNASAAQGFSKMTTEARQKGQLDTSSN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCH
TYRRINTVMQRMIPYANQMNQTGQPFQWQLAVIKSDTVNAYVAPGGKVVFYTGIVNKLNL
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEECCCCCEEEEECCCCCCCC
SDAEIAAVMGHEMTHALEEHAKSKIGAEALTGLALNIGKAYAGDSIGQAGSAALDLGSQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHHHCCCCC
GVGLPYSRNLESRADYGGLMLMAKAGYNPQAAITLWEKMNRMDGAGGPSFLSTHPSNNQR
CCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
IQDMRKNLPAAMAVYNNRR
HHHHHHCCCCEEHHHCCCC
>Mature Secondary Structure
MNKKIVMSFLAATVVTISGCASFADMAGADSATLNASAAQGFSKMTTEARQKGQLDTSSN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCH
TYRRINTVMQRMIPYANQMNQTGQPFQWQLAVIKSDTVNAYVAPGGKVVFYTGIVNKLNL
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEECCCCCEEEEECCCCCCCC
SDAEIAAVMGHEMTHALEEHAKSKIGAEALTGLALNIGKAYAGDSIGQAGSAALDLGSQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCHHHHCCCCC
GVGLPYSRNLESRADYGGLMLMAKAGYNPQAAITLWEKMNRMDGAGGPSFLSTHPSNNQR
CCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
IQDMRKNLPAAMAVYNNRR
HHHHHHCCCCEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2153656; 9278503; 1310091 [H]