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The map label for this gene is foxA [H]

Identifier: 50084427

GI number: 50084427

Start: 1238875

End: 1241073

Strand: Direct

Name: foxA [H]

Synonym: ACIAD1240

Alternate gene names: 50084427

Gene position: 1238875-1241073 (Clockwise)

Preceding gene: 50084422

Following gene: 50084429

Centisome position: 34.43

GC content: 39.02

Gene sequence:

>2199_bases
ATGTTTCAACATTTTTTATTTTTTCATCCAGGTCAAGCAGCATTTAAGTACAGTGTATTGAGTTTGATGATTTTGCAAAC
ACAACATGTCATGGCAACAGATACTTCAGAAGCAAGCAAGATTACAGCTGTTTTACCTACTTTAAAGATTGAGGCCATGA
GTGAGCTAGATCCAATCAAAAGTTACATTGATTACGATCAAGCGAATGTAACGCGTAGTGGCTTAAAAAAGAAGGATGTT
CCGCAGACCATTGATACGATTGATGTTCAGAAATACAAGATATATGGAGCAAATGATCTAAGTGTCATGTTGCAAGGTAC
ACCAGGCATCTCCACGAATTATGATACTCGTGGAGATGGTATAGTTTTACGTGGTTTTAATGCGGATACCAGTGATATCT
ATCGTGATGGTATTCGTGACAGCGGGCAGATTCGTCGCAGTACTGCCAATATCGAACGAATCGAGATATTAAAAGGGCCA
GCCTCTGTTTTATATGGCCGTAGTGGTGGTGGCGGTGTAATCAATATGGTGAGTAAGTATGCCAACTTTGACTCAAAAAG
CTCGATCGGGGTATATGCTGGTTCATGGAATAATCATGGCACGACTCTAGATTTGAATCAGGCGATTAACGAGAACTGGG
CAGTGCGCTTAACCAGTGAGTATGCAGAGGCCGATAGCTTTAGACGTGGCATAGAACAACGCCAAGTAATGGTATCACCG
AGTATAACTTATCGAAATGATGATCAAACATTACTCTGGACGACACAATATACCTACGATAAATTGCACCGTGTGCCAGA
TCGTGGGCCATCTTATTTTGATTTGGCAAAAAATAACGTGTTTCCTTCAATCAGGCAGGGTTTTGCTCATCAAGGTGATT
TTATTGATGATGAATCTCAAGTTATTCGTACAGATCTTAAATATGAGTATGTGCCTAACTGGAATTTTCATTGGGCCTTA
AGTTATCGTCAAGCTTATCAAAACTTTGATAATTACTTTGGTGGAACCTATTGTACAGTTCAATCTGCGACCTGTTTATA
TCAAGGTTTTATTCGTCAGAGTTATGCTTGGCAGCAAACCATGAATAAAACCATCACCAATACTTTTGATATTACAGGGG
AGTTGAATACAGGTCCCATTCAGCATAATGTGATGCTGGGAACAGATGTCACAAAAGAAATACGCGAACCAAAGTTAGGA
AATTACTCAAGTGGTAGTATTTCCTTATATGGTTATTTCAACCCTTACACAGGGCAAGTCATAGAGACATTTGATCGAAA
TAATGCGCAAATGACCACTCATAATCTGAGTGAAGGTCTGAATCTTGGGTTCTTTGCCCAAGATTTGATTAGTTTTAATG
ATCAGATTAAATTGTTACTGGGTGGCAGGTATGACGTTTATGATTCATCTACTCAGGTAAAAGTAAAAAATAAACTGGAT
GTTGATGAATATTACGCTAAACAGGAAGGTACGTTTAGTCCAAACGTTGGATTGATTTGGCAGCCCGTATCTGCACATAG
CTTTTATACTTCCTATAGTCGTAGTTTTGCTCCTTTTGGTGGATCTGTAGCGGTAAACTCCGTTTCTTCTAACGTGGTGA
ATGCCGAGCCACAATTTAATGATCAGTTTGAGATTGGAGTTAAAAGTGACTGGTTAGATCAGCGACTCAATACACAATTT
TCAGTCTTTGATATTCGTAAACATAACATACGTTATCAGCCTGACCGTGATAATCAGCCTGATCTTTGGGCTGTTGCAGG
TGAGCATCAATCGAAAGGTTTAGAGTTTGGTTTTATTGGACGAATGCTGGATAACGTATTTGTTCGTGGAGGCTATGGCT
ACACAGATGCAAAGGTTAAAGACAATGTTCAATATCCAAACACGGTAAATGCGCCACTTGATAAGGTATCGAAAAATACA
GGAAACCTGTTTATTCGTTATTTACCAATCGAAAGTGTATATGTTGAATCAGGTGTGACCTATCAAGGATCGTTCTATTC
TTACCAAAATGGCAATCTAAACTCTACACCTGTGCATATTGATGGTTTTTCGCGTGTAGATGCTGCGATAGGCTATAGTG
CAGATCCATGGAATGTTACTTTGGCTATTAATAATTTGACAGATAAAAAATATTGGCGATCTGCTGACCTACCTGGAACG
CCACGTAATGTATTGGTTCGTTTAAATTATCAGTTCTAA

Upstream 100 bases:

>100_bases
TAATTTTTTATGAAGTAATTGTATGAAAAATGTAATGCAAATGAGAACTTTTTGCATTAAAATTCTATTTTTCATCTCCC
TTCATTTTGGGTAAATTTTA

Downstream 100 bases:

>100_bases
AGTTAAGCAGCCTGGTTAATAAGCCTCCTAGTATCTTATATAGGAGGCTTTTCAAAATTAAAAATCAGATTTTAGAGTGT
GTGCCATATTGCTCAATCAT

Product: ferric siderophore receptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MFQHFLFFHPGQAAFKYSVLSLMILQTQHVMATDTSEASKITAVLPTLKIEAMSELDPIKSYIDYDQANVTRSGLKKKDV
PQTIDTIDVQKYKIYGANDLSVMLQGTPGISTNYDTRGDGIVLRGFNADTSDIYRDGIRDSGQIRRSTANIERIEILKGP
ASVLYGRSGGGGVINMVSKYANFDSKSSIGVYAGSWNNHGTTLDLNQAINENWAVRLTSEYAEADSFRRGIEQRQVMVSP
SITYRNDDQTLLWTTQYTYDKLHRVPDRGPSYFDLAKNNVFPSIRQGFAHQGDFIDDESQVIRTDLKYEYVPNWNFHWAL
SYRQAYQNFDNYFGGTYCTVQSATCLYQGFIRQSYAWQQTMNKTITNTFDITGELNTGPIQHNVMLGTDVTKEIREPKLG
NYSSGSISLYGYFNPYTGQVIETFDRNNAQMTTHNLSEGLNLGFFAQDLISFNDQIKLLLGGRYDVYDSSTQVKVKNKLD
VDEYYAKQEGTFSPNVGLIWQPVSAHSFYTSYSRSFAPFGGSVAVNSVSSNVVNAEPQFNDQFEIGVKSDWLDQRLNTQF
SVFDIRKHNIRYQPDRDNQPDLWAVAGEHQSKGLEFGFIGRMLDNVFVRGGYGYTDAKVKDNVQYPNTVNAPLDKVSKNT
GNLFIRYLPIESVYVESGVTYQGSFYSYQNGNLNSTPVHIDGFSRVDAAIGYSADPWNVTLAINNLTDKKYWRSADLPGT
PRNVLVRLNYQF

Sequences:

>Translated_732_residues
MFQHFLFFHPGQAAFKYSVLSLMILQTQHVMATDTSEASKITAVLPTLKIEAMSELDPIKSYIDYDQANVTRSGLKKKDV
PQTIDTIDVQKYKIYGANDLSVMLQGTPGISTNYDTRGDGIVLRGFNADTSDIYRDGIRDSGQIRRSTANIERIEILKGP
ASVLYGRSGGGGVINMVSKYANFDSKSSIGVYAGSWNNHGTTLDLNQAINENWAVRLTSEYAEADSFRRGIEQRQVMVSP
SITYRNDDQTLLWTTQYTYDKLHRVPDRGPSYFDLAKNNVFPSIRQGFAHQGDFIDDESQVIRTDLKYEYVPNWNFHWAL
SYRQAYQNFDNYFGGTYCTVQSATCLYQGFIRQSYAWQQTMNKTITNTFDITGELNTGPIQHNVMLGTDVTKEIREPKLG
NYSSGSISLYGYFNPYTGQVIETFDRNNAQMTTHNLSEGLNLGFFAQDLISFNDQIKLLLGGRYDVYDSSTQVKVKNKLD
VDEYYAKQEGTFSPNVGLIWQPVSAHSFYTSYSRSFAPFGGSVAVNSVSSNVVNAEPQFNDQFEIGVKSDWLDQRLNTQF
SVFDIRKHNIRYQPDRDNQPDLWAVAGEHQSKGLEFGFIGRMLDNVFVRGGYGYTDAKVKDNVQYPNTVNAPLDKVSKNT
GNLFIRYLPIESVYVESGVTYQGSFYSYQNGNLNSTPVHIDGFSRVDAAIGYSADPWNVTLAINNLTDKKYWRSADLPGT
PRNVLVRLNYQF
>Mature_732_residues
MFQHFLFFHPGQAAFKYSVLSLMILQTQHVMATDTSEASKITAVLPTLKIEAMSELDPIKSYIDYDQANVTRSGLKKKDV
PQTIDTIDVQKYKIYGANDLSVMLQGTPGISTNYDTRGDGIVLRGFNADTSDIYRDGIRDSGQIRRSTANIERIEILKGP
ASVLYGRSGGGGVINMVSKYANFDSKSSIGVYAGSWNNHGTTLDLNQAINENWAVRLTSEYAEADSFRRGIEQRQVMVSP
SITYRNDDQTLLWTTQYTYDKLHRVPDRGPSYFDLAKNNVFPSIRQGFAHQGDFIDDESQVIRTDLKYEYVPNWNFHWAL
SYRQAYQNFDNYFGGTYCTVQSATCLYQGFIRQSYAWQQTMNKTITNTFDITGELNTGPIQHNVMLGTDVTKEIREPKLG
NYSSGSISLYGYFNPYTGQVIETFDRNNAQMTTHNLSEGLNLGFFAQDLISFNDQIKLLLGGRYDVYDSSTQVKVKNKLD
VDEYYAKQEGTFSPNVGLIWQPVSAHSFYTSYSRSFAPFGGSVAVNSVSSNVVNAEPQFNDQFEIGVKSDWLDQRLNTQF
SVFDIRKHNIRYQPDRDNQPDLWAVAGEHQSKGLEFGFIGRMLDNVFVRGGYGYTDAKVKDNVQYPNTVNAPLDKVSKNT
GNLFIRYLPIESVYVESGVTYQGSFYSYQNGNLNSTPVHIDGFSRVDAAIGYSADPWNVTLAINNLTDKKYWRSADLPGT
PRNVLVRLNYQF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=717, Percent_Identity=25.9414225941423, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1786344, Length=775, Percent_Identity=22.8387096774194, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1787344, Length=780, Percent_Identity=24.2307692307692, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82757; Mature: 82757

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQHFLFFHPGQAAFKYSVLSLMILQTQHVMATDTSEASKITAVLPTLKIEAMSELDPIK
CCCEEEEECCCCHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEECCEEEHHHHHHHHHH
SYIDYDQANVTRSGLKKKDVPQTIDTIDVQKYKIYGANDLSVMLQGTPGISTNYDTRGDG
HHHCCCCCHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCE
IVLRGFNADTSDIYRDGIRDSGQIRRSTANIERIEILKGPASVLYGRSGGGGVINMVSKY
EEEEECCCCHHHHHHHCCCCCCCEEHHCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHH
ANFDSKSSIGVYAGSWNNHGTTLDLNQAINENWAVRLTSEYAEADSFRRGIEQRQVMVSP
CCCCCCCCCEEEECCCCCCCCEEEHHHHCCCCEEEEEEHHHHHHHHHHHCHHHCEEEECC
SITYRNDDQTLLWTTQYTYDKLHRVPDRGPSYFDLAKNNVFPSIRQGFAHQGDFIDDESQ
CEEEECCCCEEEEEECCCHHHHHCCCCCCCCEEEHHHCCCCHHHHHCCCCCCCCCCCCHH
VIRTDLKYEYVPNWNFHWALSYRQAYQNFDNYFGGTYCTVQSATCLYQGFIRQSYAWQQT
HEEECCEEEECCCCCEEEEEHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHH
MNKTITNTFDITGELNTGPIQHNVMLGTDVTKEIREPKLGNYSSGSISLYGYFNPYTGQV
HHHHHCEEEEEEECCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCHH
IETFDRNNAQMTTHNLSEGLNLGFFAQDLISFNDQIKLLLGGRYDVYDSSTQVKVKNKLD
HHHHCCCCCEEEECCHHCCCCCCHHHHHHHCCCCEEEEEECCEEEEECCCCEEEEECCCC
VDEYYAKQEGTFSPNVGLIWQPVSAHSFYTSYSRSFAPFGGSVAVNSVSSNVVNAEPQFN
HHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCEEEECCCCCEEECCCCCC
DQFEIGVKSDWLDQRLNTQFSVFDIRKHNIRYQPDRDNQPDLWAVAGEHQSKGLEFGFIG
CCEEECCCCHHHHHHHCCEEEEEEEEECCEEECCCCCCCCCEEEEECCCCCCCCCHHHHH
RMLDNVFVRGGYGYTDAKVKDNVQYPNTVNAPLDKVSKNTGNLFIRYLPIESVYVESGVT
HHHHHHEEECCCCCCCCCEECCCCCCCCCCCCHHHHCCCCCCEEEEEECCCEEEECCCCE
YQGSFYSYQNGNLNSTPVHIDGFSRVDAAIGYSADPWNVTLAINNLTDKKYWRSADLPGT
ECCCEEEECCCCCCCCCEEECCCHHHHHHCCCCCCCEEEEEEEECCCCCHHHCCCCCCCC
PRNVLVRLNYQF
CCEEEEEEEECC
>Mature Secondary Structure
MFQHFLFFHPGQAAFKYSVLSLMILQTQHVMATDTSEASKITAVLPTLKIEAMSELDPIK
CCCEEEEECCCCHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEEECCEEEHHHHHHHHHH
SYIDYDQANVTRSGLKKKDVPQTIDTIDVQKYKIYGANDLSVMLQGTPGISTNYDTRGDG
HHHCCCCCHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCE
IVLRGFNADTSDIYRDGIRDSGQIRRSTANIERIEILKGPASVLYGRSGGGGVINMVSKY
EEEEECCCCHHHHHHHCCCCCCCEEHHCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHH
ANFDSKSSIGVYAGSWNNHGTTLDLNQAINENWAVRLTSEYAEADSFRRGIEQRQVMVSP
CCCCCCCCCEEEECCCCCCCCEEEHHHHCCCCEEEEEEHHHHHHHHHHHCHHHCEEEECC
SITYRNDDQTLLWTTQYTYDKLHRVPDRGPSYFDLAKNNVFPSIRQGFAHQGDFIDDESQ
CEEEECCCCEEEEEECCCHHHHHCCCCCCCCEEEHHHCCCCHHHHHCCCCCCCCCCCCHH
VIRTDLKYEYVPNWNFHWALSYRQAYQNFDNYFGGTYCTVQSATCLYQGFIRQSYAWQQT
HEEECCEEEECCCCCEEEEEHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHH
MNKTITNTFDITGELNTGPIQHNVMLGTDVTKEIREPKLGNYSSGSISLYGYFNPYTGQV
HHHHHCEEEEEEECCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCHH
IETFDRNNAQMTTHNLSEGLNLGFFAQDLISFNDQIKLLLGGRYDVYDSSTQVKVKNKLD
HHHHCCCCCEEEECCHHCCCCCCHHHHHHHCCCCEEEEEECCEEEEECCCCEEEEECCCC
VDEYYAKQEGTFSPNVGLIWQPVSAHSFYTSYSRSFAPFGGSVAVNSVSSNVVNAEPQFN
HHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCEEEECCCCCEEECCCCCC
DQFEIGVKSDWLDQRLNTQFSVFDIRKHNIRYQPDRDNQPDLWAVAGEHQSKGLEFGFIG
CCEEECCCCHHHHHHHCCEEEEEEEEECCEEECCCCCCCCCEEEEECCCCCCCCCHHHHH
RMLDNVFVRGGYGYTDAKVKDNVQYPNTVNAPLDKVSKNTGNLFIRYLPIESVYVESGVT
HHHHHHEEECCCCCCCCCEECCCCCCCCCCCCHHHHCCCCCCEEEEEECCCEEEECCCCE
YQGSFYSYQNGNLNSTPVHIDGFSRVDAAIGYSADPWNVTLAINNLTDKKYWRSADLPGT
ECCCEEEECCCCCCCCCEEECCCHHHHHHCCCCCCCEEEEEEEECCCCCHHHCCCCCCCC
PRNVLVRLNYQF
CCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]