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The map label for this gene is argD [H]

Identifier: 50084418

GI number: 50084418

Start: 1231743

End: 1232957

Strand: Reverse

Name: argD [H]

Synonym: ACIAD1231

Alternate gene names: 50084418

Gene position: 1232957-1231743 (Counterclockwise)

Preceding gene: 50084420

Following gene: 50084414

Centisome position: 34.26

GC content: 42.47

Gene sequence:

>1215_bases
ATGAATCACATCACCCTCGCCCCTGTACAATCTGATCAACCTACACATTTGATGGCAACCTATGGCCGCCAAGCGATCAG
TTTTGTTCGAGGCCGTGGATCTTATCTATATACAGAAGATGGAACTGAGTATCTTGATGCGCTAACAGGAATTGCAGTAT
GTGGTTTAGGCCACGCCCATTCTGTCATTGCAGAAGCCATTGCAGAGCAAGCTGCGACGCTCGTACACACCAGTAATATT
TTTGAAATTCCTTGGCAAACAGCAGCAGCACAAAAGCTAGCCGAAGTTTCAGGCATGCAAGAAATTTTCTTTTCAAATAG
TGGTGCAGAATCAAATGAAGGTGCAATCAAAATTGCACGCAAATATGGTTCGCAACAAGGTATCCAGCATCCAAAGATTA
TTGTTGCCGAAAAATCCTTTCATGGCCGTACCTTAGCGACCTTATCCGCTACAGGAAATGCCAAAGTGCAGGAAGGTTTT
TTCCCCCTAGTTGAAGGTTTTATCCGTGTACCATTTGGTGATATTGAAGCTATTCAGGAAGCTGCTCTCCATCACCCTGA
TATTGTTGCAATTTTAGTTGAACCAATTCAAGGTGAAGGCGGAATCAATACTGCGCCACAAGGCTTTAGCTATTTAGAAG
AAATTCGAGCGTTATGTAACCAACACAATTGGCTAATGATGCTTGATGAAATTCAAACAGGTAATGGACGTACAGGTAAA
TTTTTTGCTTATCAACACACCAATATTACACCAGATGTACTCACAACTGCCAAAGGCTTAGGTAACGGCTTCCCTGTCGG
AGCAGTCATGACTCAAGGAAAAGCCGTAGGTTTACTAGGGCCTGGTAGTCATGGTTCGACGTATGGTGGCACTGTATTGG
GTTCTCGTGTGGTATACACTGTAATTGATACGATTCAGAAAGAAAACGTGGTTGAAAACGCCGATAAAATGGGTCGATAT
ATTGTCGAGCAATTACGTCAGGCATTTAATGAACTTGATATACAAGTACGTGGATTTGGCATGATGATTGGTATTGAATT
ACCTAAGCCGTGTGCAGAACTAGTCAACATTACTCGCGATGAATATAAACTGATTGTCAATGTAACTGCGGGCAATGTTG
TGCGTTTACTTCCACCACTTAACATGTCCAAAGATCAAGCCGATGACTTGATCAATCGTTTGGTTCCAGCAATTCAGAAC
TTTCTTGCTGCTTAA

Upstream 100 bases:

>100_bases
TGAGATTTCTATTTTAATTTTGGTTTTACTCTTTCATTCCGTGATGGTTTTTGCTTATATAAACCCTCCTATTCATTTCA
TTCACAGATAAGAGCACGTC

Downstream 100 bases:

>100_bases
TCTGAATATCTTTAATGCAATAAAAAAGCCGCTTAAGCGGCTTTTTTATTGCATTAAGAAACTTCCTGTAAATTACGACC
ACCTGGCAACTGACTAAAAT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNHITLAPVQSDQPTHLMATYGRQAISFVRGRGSYLYTEDGTEYLDALTGIAVCGLGHAHSVIAEAIAEQAATLVHTSNI
FEIPWQTAAAQKLAEVSGMQEIFFSNSGAESNEGAIKIARKYGSQQGIQHPKIIVAEKSFHGRTLATLSATGNAKVQEGF
FPLVEGFIRVPFGDIEAIQEAALHHPDIVAILVEPIQGEGGINTAPQGFSYLEEIRALCNQHNWLMMLDEIQTGNGRTGK
FFAYQHTNITPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYTVIDTIQKENVVENADKMGRY
IVEQLRQAFNELDIQVRGFGMMIGIELPKPCAELVNITRDEYKLIVNVTAGNVVRLLPPLNMSKDQADDLINRLVPAIQN
FLAA

Sequences:

>Translated_404_residues
MNHITLAPVQSDQPTHLMATYGRQAISFVRGRGSYLYTEDGTEYLDALTGIAVCGLGHAHSVIAEAIAEQAATLVHTSNI
FEIPWQTAAAQKLAEVSGMQEIFFSNSGAESNEGAIKIARKYGSQQGIQHPKIIVAEKSFHGRTLATLSATGNAKVQEGF
FPLVEGFIRVPFGDIEAIQEAALHHPDIVAILVEPIQGEGGINTAPQGFSYLEEIRALCNQHNWLMMLDEIQTGNGRTGK
FFAYQHTNITPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYTVIDTIQKENVVENADKMGRY
IVEQLRQAFNELDIQVRGFGMMIGIELPKPCAELVNITRDEYKLIVNVTAGNVVRLLPPLNMSKDQADDLINRLVPAIQN
FLAA
>Mature_404_residues
MNHITLAPVQSDQPTHLMATYGRQAISFVRGRGSYLYTEDGTEYLDALTGIAVCGLGHAHSVIAEAIAEQAATLVHTSNI
FEIPWQTAAAQKLAEVSGMQEIFFSNSGAESNEGAIKIARKYGSQQGIQHPKIIVAEKSFHGRTLATLSATGNAKVQEGF
FPLVEGFIRVPFGDIEAIQEAALHHPDIVAILVEPIQGEGGINTAPQGFSYLEEIRALCNQHNWLMMLDEIQTGNGRTGK
FFAYQHTNITPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYTVIDTIQKENVVENADKMGRY
IVEQLRQAFNELDIQVRGFGMMIGIELPKPCAELVNITRDEYKLIVNVTAGNVVRLLPPLNMSKDQADDLINRLVPAIQN
FLAA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=34.2036553524804, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI284507298, Length=303, Percent_Identity=36.963696369637, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=28.5057471264368, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI24119277, Length=409, Percent_Identity=27.6283618581907, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=25.7211538461538, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=25.2403846153846, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=25.4593175853018, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI188536080, Length=450, Percent_Identity=22.8888888888889, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI38679950, Length=450, Percent_Identity=22.8888888888889, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI38679946, Length=450, Percent_Identity=22.8888888888889, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=39.6325459317585, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=37.8865979381443, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI145693181, Length=390, Percent_Identity=34.1025641025641, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1787560, Length=392, Percent_Identity=32.1428571428571, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1789016, Length=390, Percent_Identity=30.7692307692308, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1786349, Length=355, Percent_Identity=26.7605633802817, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786991, Length=401, Percent_Identity=24.4389027431421, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=387, Percent_Identity=31.0077519379845, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI25144274, Length=295, Percent_Identity=32.5423728813559, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=29.7235023041475, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=28.3062645011601, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17541228, Length=384, Percent_Identity=25, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71981843, Length=169, Percent_Identity=26.0355029585799, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=403, Percent_Identity=33.7468982630273, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=391, Percent_Identity=32.4808184143223, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324386, Length=344, Percent_Identity=25.8720930232558, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321456, Length=458, Percent_Identity=22.9257641921397, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357415, Length=372, Percent_Identity=33.8709677419355, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI28574759, Length=430, Percent_Identity=30.2325581395349, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=29.7423887587822, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI21356575, Length=416, Percent_Identity=28.6057692307692, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281366494, Length=373, Percent_Identity=25.201072386059, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667139, Length=373, Percent_Identity=25.201072386059, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667143, Length=373, Percent_Identity=25.201072386059, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43655; Mature: 43655

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHITLAPVQSDQPTHLMATYGRQAISFVRGRGSYLYTEDGTEYLDALTGIAVCGLGHAH
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCHHH
SVIAEAIAEQAATLVHTSNIFEIPWQTAAAQKLAEVSGMQEIFFSNSGAESNEGAIKIAR
HHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
KYGSQQGIQHPKIIVAEKSFHGRTLATLSATGNAKVQEGFFPLVEGFIRVPFGDIEAIQE
HHCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCHHHCCHHHHHHHHCCCCCHHHHHHH
AALHHPDIVAILVEPIQGEGGINTAPQGFSYLEEIRALCNQHNWLMMLDEIQTGNGRTGK
HHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCE
FFAYQHTNITPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYT
EEEEECCCCCHHHHHHHHHCCCCCCCHHEEECCCEEEEECCCCCCCCCCCHHHHHHHHHH
VIDTIQKENVVENADKMGRYIVEQLRQAFNELDIQVRGFGMMIGIELPKPCAELVNITRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCHHHHHHHHCCCC
EYKLIVNVTAGNVVRLLPPLNMSKDQADDLINRLVPAIQNFLAA
CEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHITLAPVQSDQPTHLMATYGRQAISFVRGRGSYLYTEDGTEYLDALTGIAVCGLGHAH
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCHHH
SVIAEAIAEQAATLVHTSNIFEIPWQTAAAQKLAEVSGMQEIFFSNSGAESNEGAIKIAR
HHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
KYGSQQGIQHPKIIVAEKSFHGRTLATLSATGNAKVQEGFFPLVEGFIRVPFGDIEAIQE
HHCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCHHHCCHHHHHHHHCCCCCHHHHHHH
AALHHPDIVAILVEPIQGEGGINTAPQGFSYLEEIRALCNQHNWLMMLDEIQTGNGRTGK
HHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCE
FFAYQHTNITPDVLTTAKGLGNGFPVGAVMTQGKAVGLLGPGSHGSTYGGTVLGSRVVYT
EEEEECCCCCHHHHHHHHHCCCCCCCHHEEECCCEEEEECCCCCCCCCCCHHHHHHHHHH
VIDTIQKENVVENADKMGRYIVEQLRQAFNELDIQVRGFGMMIGIELPKPCAELVNITRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCHHHHHHHHCCCC
EYKLIVNVTAGNVVRLLPPLNMSKDQADDLINRLVPAIQNFLAA
CEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]