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The map label for this gene is slyD [H]

Identifier: 50084373

GI number: 50084373

Start: 1180517

End: 1180999

Strand: Reverse

Name: slyD [H]

Synonym: ACIAD1183

Alternate gene names: 50084373

Gene position: 1180999-1180517 (Counterclockwise)

Preceding gene: 50084374

Following gene: 50084372

Centisome position: 32.82

GC content: 44.1

Gene sequence:

>483_bases
ATGACTGCTATTGCAAATAACCACGTGGTTTCATTCCACTACAAATTGACAAATGCTGAAGGTGAAACTCTTGACCAGTC
TCAAGGCGAACCACTTGCATATTTGCACGGTGCAGGCAACATTATTCCTGGTTTGGAAAATGCATTAACAGGTAAAGCTG
TTGGTGACAAATTTACTGTCAACGTTCCTGCTGCTGAAGGTTATGGCGAATACAACCCAGACCTAGTACAGGAAGTTCCA
GCACAAATGTTTCAGGGTGTTGAAAACATCCAGCCTGGCATGCAATTCCAAGCTCAAACTGATGACGGCGTTCAGATCGT
TACTGTGAAAGCTGTAGAAGGTGACAACATCGTTGTTGACGCTAACTTCCCACTTGCTGGCCAAGATTTAACGTTTGAAG
TTGAAATCGTTGAAATCCGTGATGCATCTCAAGAAGAGCTAGATCACGGTCATGTACACGGTGTAGGTGGTCATCACCAC
TAA

Upstream 100 bases:

>100_bases
GCTTAAATGTGAAATTTGTGAGTTTTTACGATTTTTAATCTACAAAATTCTTTTTTCACTTTATGATGTGACCTTAAATT
GATTGAATGGATCAACAAAC

Downstream 100 bases:

>100_bases
TCTGGAAGGTTTTTCCAGTCAAGGCAAAGTTTTTACTTTGCCTTGCTTGTTTTTGAAGATTTTTTCTGACCTAAAAATAA
AAATCGTCCCAATTACCAAC

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKAVGDKFTVNVPAAEGYGEYNPDLVQEVP
AQMFQGVENIQPGMQFQAQTDDGVQIVTVKAVEGDNIVVDANFPLAGQDLTFEVEIVEIRDASQEELDHGHVHGVGGHHH

Sequences:

>Translated_160_residues
MTAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKAVGDKFTVNVPAAEGYGEYNPDLVQEVP
AQMFQGVENIQPGMQFQAQTDDGVQIVTVKAVEGDNIVVDANFPLAGQDLTFEVEIVEIRDASQEELDHGHVHGVGGHHH
>Mature_159_residues
TAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKAVGDKFTVNVPAAEGYGEYNPDLVQEVPA
QMFQGVENIQPGMQFQAQTDDGVQIVTVKAVEGDNIVVDANFPLAGQDLTFEVEIVEIRDASQEELDHGHVHGVGGHHH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=50.3401360544218, Blast_Score=134, Evalue=2e-33,
Organism=Escherichia coli, GI1786211, Length=145, Percent_Identity=33.1034482758621, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17152; Mature: 17021

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKAVGDKFTV
CCEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCCEEEE
NVPAAEGYGEYNPDLVQEVPAQMFQGVENIQPGMQFQAQTDDGVQIVTVKAVEGDNIVVD
ECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEEECCCCCEEEEEEEEECCCEEEEE
ANFPLAGQDLTFEVEIVEIRDASQEELDHGHVHGVGGHHH
CCCCCCCCCEEEEEEEEEECCCCHHHCCCCEEECCCCCCC
>Mature Secondary Structure 
TAIANNHVVSFHYKLTNAEGETLDQSQGEPLAYLHGAGNIIPGLENALTGKAVGDKFTV
CEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHCCCCCCCCEEEE
NVPAAEGYGEYNPDLVQEVPAQMFQGVENIQPGMQFQAQTDDGVQIVTVKAVEGDNIVVD
ECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEEECCCCCEEEEEEEEECCCEEEEE
ANFPLAGQDLTFEVEIVEIRDASQEELDHGHVHGVGGHHH
CCCCCCCCCEEEEEEEEEECCCCHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]