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The map label for this gene is mqo

Identifier: 50084210

GI number: 50084210

Start: 994715

End: 996346

Strand: Reverse

Name: mqo

Synonym: ACIAD1007

Alternate gene names: 50084210

Gene position: 996346-994715 (Counterclockwise)

Preceding gene: 50084211

Following gene: 50084209

Centisome position: 27.69

GC content: 41.24

Gene sequence:

>1632_bases
ATGAAAAAGTTTTTGAAATACCTCGCGGTATTCCTTGTTGTTCTTTTAATTGCAGCGATCGCCTTCCTCTTTAGGCCTAT
TGCTTCTAAAAAAATTCAAACCTCTGCCAATGAGCCTGTAGTCGATGTTGTTCTGGTAGGTGGCGGTATCATGAGTGCCA
CGCTGGGAACGTATTTGACTGAACTTGAGCCAAACTGGCAAATTCGGATGTATGAACGCCTTGACCGCGTTGCTCAAGAA
AGCTCAAATGGTTTTAATAATGCAGGTACTGGCCACTCAGGCTTTATGGAAATGAACTATACCGAAGAAAAAGACGGTAA
AATGGACATTTCTAAAGCTGTGAAAGTTGCTGAACAGTTTGAAATTTCAAAACAGTTCTGGGCATACCAAGTCAAACACA
ATGTACTTGGTCAACCATCAAGTTTTATCAACCCAGTGCCGCATCATGCATTTGTATGGGGTGATAATGTTGCATTTCTT
GAAAAACGTTATGCAGCGATGATTAAAAATCCACTGTTTTATGGTATGCAATTTACTGAGAATGCAAACCAGATTAAACA
ATGGGCGCCTCTCACCATGGAAGGCCGTGATCCTGCACAGAAAGTTGCAGCAACACGTATGGAAATTGGTTCTGATGTAA
ACTACGGTGCAATCACCACTCAATTGGTGAATAACCTAGATAAACATCAAAATTTCAAACTTTCAACTTCAAGTGAAGTT
ACTGGCATTAGTCAAAACGATGACAAAACCTGGACAGTTGCTTTCAAGAACTTAAAAACAGGCAAAGCGGATCATGTGAA
AACACGTTTTGTGTTTATTGGTGCAGGCGGTGCAAGTGTCAAACTTTTACAGATGACCGGTTTACCTGAATCTAAGCAGT
ATGCAGGCTTCCCAGTGGGCGGTGTGTTCTTGATGACTGACAATCCTAAAATTGCAGCAGAACACACAGCAAAACTATAT
GGCCGCGCCGAGCTAGGTGCGCCGCCAATGTCTGTACCTCACATTGATACTCGTTATATCGATGGTAAGAAATATGTTTT
ATTTGGACCATTTGCAACCTATTCAAACAAGTTCCTGAAACAAGGCTCTCAGTTTGATTTGTTGGCATCAACCAATAAAA
ACAACGTGTTACCAATGACTGCTGTTGGTATGGAAAATCTTGATTTGGTGAAATATTTAGTTAGCCAAGTGATGATGACC
GATGAAGATCGTTTCAATGAGTTGAAAAAGTACTACCCAAATGCGAAACGTGAAGACTGGCGTTTGAACCAAGGTGGCCA
GCGTGTTCAGGTCATCAAAAAAGAAGAAGGCAAACCAGCCAAACTTCAATTTGGTACAGAAGTATTTGTTTCTAAAGACC
GTTCAGTTACTGCACTGATGGGTGCATCTCCTGGCGCGTCTACTTCACCATACATTATGTTGAATTTGCTTGAAAAAGCT
TTCCCACAACAAGTGAAAGGTGAATGGAATCCAAAGCTGCACGAAATCGTAAGATCGTACAAACAAGATTTAAGTGATAA
TCCTGTACTTCTTGATCAAGTGCGTCAGTACACCAGCCAAACACTTGGCCTGCACTACACACCATTGACTCAAGCTGATT
TCGCCAAGATTGCTGCAAGTCAGTCTAAATAA

Upstream 100 bases:

>100_bases
AACTTAGATTTACCGCCATTTCCAGCATTTTTTATTTTTCTTTTTTCCCGCTCTTCGCTTCTGCGCGATGCTAATCACCT
ACCCCAAGGTCCTTAATCGC

Downstream 100 bases:

>100_bases
ACTACGCTGTTTCAAGAAAAGGATGAGCGCTTGCTCATCCTTTTTTATTCTCTTGTTCTTTGGGCTTTTATCATCTGTTT
ATGTCATCTTCTTCTGATTT

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MKKFLKYLAVFLVVLLIAAIAFLFRPIASKKIQTSANEPVVDVVLVGGGIMSATLGTYLTELEPNWQIRMYERLDRVAQE
SSNGFNNAGTGHSGFMEMNYTEEKDGKMDISKAVKVAEQFEISKQFWAYQVKHNVLGQPSSFINPVPHHAFVWGDNVAFL
EKRYAAMIKNPLFYGMQFTENANQIKQWAPLTMEGRDPAQKVAATRMEIGSDVNYGAITTQLVNNLDKHQNFKLSTSSEV
TGISQNDDKTWTVAFKNLKTGKADHVKTRFVFIGAGGASVKLLQMTGLPESKQYAGFPVGGVFLMTDNPKIAAEHTAKLY
GRAELGAPPMSVPHIDTRYIDGKKYVLFGPFATYSNKFLKQGSQFDLLASTNKNNVLPMTAVGMENLDLVKYLVSQVMMT
DEDRFNELKKYYPNAKREDWRLNQGGQRVQVIKKEEGKPAKLQFGTEVFVSKDRSVTALMGASPGASTSPYIMLNLLEKA
FPQQVKGEWNPKLHEIVRSYKQDLSDNPVLLDQVRQYTSQTLGLHYTPLTQADFAKIAASQSK

Sequences:

>Translated_543_residues
MKKFLKYLAVFLVVLLIAAIAFLFRPIASKKIQTSANEPVVDVVLVGGGIMSATLGTYLTELEPNWQIRMYERLDRVAQE
SSNGFNNAGTGHSGFMEMNYTEEKDGKMDISKAVKVAEQFEISKQFWAYQVKHNVLGQPSSFINPVPHHAFVWGDNVAFL
EKRYAAMIKNPLFYGMQFTENANQIKQWAPLTMEGRDPAQKVAATRMEIGSDVNYGAITTQLVNNLDKHQNFKLSTSSEV
TGISQNDDKTWTVAFKNLKTGKADHVKTRFVFIGAGGASVKLLQMTGLPESKQYAGFPVGGVFLMTDNPKIAAEHTAKLY
GRAELGAPPMSVPHIDTRYIDGKKYVLFGPFATYSNKFLKQGSQFDLLASTNKNNVLPMTAVGMENLDLVKYLVSQVMMT
DEDRFNELKKYYPNAKREDWRLNQGGQRVQVIKKEEGKPAKLQFGTEVFVSKDRSVTALMGASPGASTSPYIMLNLLEKA
FPQQVKGEWNPKLHEIVRSYKQDLSDNPVLLDQVRQYTSQTLGLHYTPLTQADFAKIAASQSK
>Mature_543_residues
MKKFLKYLAVFLVVLLIAAIAFLFRPIASKKIQTSANEPVVDVVLVGGGIMSATLGTYLTELEPNWQIRMYERLDRVAQE
SSNGFNNAGTGHSGFMEMNYTEEKDGKMDISKAVKVAEQFEISKQFWAYQVKHNVLGQPSSFINPVPHHAFVWGDNVAFL
EKRYAAMIKNPLFYGMQFTENANQIKQWAPLTMEGRDPAQKVAATRMEIGSDVNYGAITTQLVNNLDKHQNFKLSTSSEV
TGISQNDDKTWTVAFKNLKTGKADHVKTRFVFIGAGGASVKLLQMTGLPESKQYAGFPVGGVFLMTDNPKIAAEHTAKLY
GRAELGAPPMSVPHIDTRYIDGKKYVLFGPFATYSNKFLKQGSQFDLLASTNKNNVLPMTAVGMENLDLVKYLVSQVMMT
DEDRFNELKKYYPNAKREDWRLNQGGQRVQVIKKEEGKPAKLQFGTEVFVSKDRSVTALMGASPGASTSPYIMLNLLEKA
FPQQVKGEWNPKLHEIVRSYKQDLSDNPVLLDQVRQYTSQTLGLHYTPLTQADFAKIAASQSK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=536, Percent_Identity=57.089552238806, Blast_Score=622, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_ACIAD (Q6FDG0)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045720.1
- ProteinModelPortal:   Q6FDG0
- STRING:   Q6FDG0
- GeneID:   2878499
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1007
- NMPDR:   fig|62977.3.peg.1058
- eggNOG:   COG0579
- HOGENOM:   HBG289663
- OMA:   GKRMILF
- PhylomeDB:   Q6FDG0
- ProtClustDB:   PRK05257
- BioCyc:   ASP62977:ACIAD1007-MONOMER
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 60682; Mature: 60682

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLKYLAVFLVVLLIAAIAFLFRPIASKKIQTSANEPVVDVVLVGGGIMSATLGTYLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHH
ELEPNWQIRMYERLDRVAQESSNGFNNAGTGHSGFMEMNYTEEKDGKMDISKAVKVAEQF
HCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
EISKQFWAYQVKHNVLGQPSSFINPVPHHAFVWGDNVAFLEKRYAAMIKNPLFYGMQFTE
HHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCHHCCEEECC
NANQIKQWAPLTMEGRDPAQKVAATRMEIGSDVNYGAITTQLVNNLDKHQNFKLSTSSEV
CHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCC
TGISQNDDKTWTVAFKNLKTGKADHVKTRFVFIGAGGASVKLLQMTGLPESKQYAGFPVG
CCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCC
GVFLMTDNPKIAAEHTAKLYGRAELGAPPMSVPHIDTRYIDGKKYVLFGPFATYSNKFLK
CEEEEECCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCEEECCCEEEEECCHHHHHHHHHH
QGSQFDLLASTNKNNVLPMTAVGMENLDLVKYLVSQVMMTDEDRFNELKKYYPNAKREDW
CCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
RLNQGGQRVQVIKKEEGKPAKLQFGTEVFVSKDRSVTALMGASPGASTSPYIMLNLLEKA
CCCCCCCEEEEEECCCCCCCEEEECCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHH
FPQQVKGEWNPKLHEIVRSYKQDLSDNPVLLDQVRQYTSQTLGLHYTPLTQADFAKIAAS
CCHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHHHHHHHC
QSK
CCC
>Mature Secondary Structure
MKKFLKYLAVFLVVLLIAAIAFLFRPIASKKIQTSANEPVVDVVLVGGGIMSATLGTYLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHH
ELEPNWQIRMYERLDRVAQESSNGFNNAGTGHSGFMEMNYTEEKDGKMDISKAVKVAEQF
HCCCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
EISKQFWAYQVKHNVLGQPSSFINPVPHHAFVWGDNVAFLEKRYAAMIKNPLFYGMQFTE
HHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCHHCCEEECC
NANQIKQWAPLTMEGRDPAQKVAATRMEIGSDVNYGAITTQLVNNLDKHQNFKLSTSSEV
CHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEECCCCC
TGISQNDDKTWTVAFKNLKTGKADHVKTRFVFIGAGGASVKLLQMTGLPESKQYAGFPVG
CCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCC
GVFLMTDNPKIAAEHTAKLYGRAELGAPPMSVPHIDTRYIDGKKYVLFGPFATYSNKFLK
CEEEEECCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCEEECCCEEEEECCHHHHHHHHHH
QGSQFDLLASTNKNNVLPMTAVGMENLDLVKYLVSQVMMTDEDRFNELKKYYPNAKREDW
CCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
RLNQGGQRVQVIKKEEGKPAKLQFGTEVFVSKDRSVTALMGASPGASTSPYIMLNLLEKA
CCCCCCCEEEEEECCCCCCCEEEECCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHH
FPQQVKGEWNPKLHEIVRSYKQDLSDNPVLLDQVRQYTSQTLGLHYTPLTQADFAKIAAS
CCHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHHHHHHHC
QSK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA