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The map label for this gene is shlB [H]

Identifier: 50084146

GI number: 50084146

Start: 921123

End: 922922

Strand: Direct

Name: shlB [H]

Synonym: ACIAD0939

Alternate gene names: 50084146

Gene position: 921123-922922 (Clockwise)

Preceding gene: 50084145

Following gene: 50084147

Centisome position: 25.6

GC content: 43.94

Gene sequence:

>1800_bases
ATGAAAATCACAATTGTTGATTGTAAAGTTATTCTAAAAAAAACAGCATTATGTCTTGGTGTATGCAGTAGCATACACGG
CCTGGTTCATGCCGCAGATTTGACTCAGCAGGAGATCACAGAACAACAGCGCCGCGATGCACAAAAAAATATGGCGGATA
ATCAGATTCGCCAGCAACAACGAGATGATGCTCTCCAAAAACAAATCCAGCCTGAAGTAAATGTCAATCTGGGTCCGCAA
AACGCTAAGCTCCAAGCTCAGCAACTTCAATATCTGCGTTCGCATAGTGAAAGCCCGTGCTTTGAAATTAAAGATATTCA
TTTACAAGGTGAGAAGGCAGAGCATTTTTTATTTGCTCTTAATGAAATCACGCAGGGAACACACAATATTATTGGACGTT
GTCTTGGGGTACAGGGATTAAATCAGGCATTAGATCTGGTACAAAACCGTATTATTTCGGCGGGTTATGTCACTTCACGT
GTACTTCTACCTGCACAAAATATTGCATCGGGTCAGCTTAAAATTGCAGTGATTGCAGGTCGTGTCGATCATGTGAAATT
TGCCGAAGGTACTTCGTCACGCGCACATAAAATCAATGCACTCCCGATCAAATCGGGTGATTTGCTCAACCTACATGATC
TTGAGCAGGGGCTTGAAAACTTTAAGCGAGTACCCACTGTCGAAGCAGATTTTAAAATTCAGCCAGCCGAAAATAACAAT
ACGCCAGGTTATAGTGACGTCATTCTTGCATGGCAACAATCCAAGCCCTATCGCATTAACTTGAGTCTGGACGATTCTGG
TTCAGACTCAACGGGTAAATATCAAGGCACAGCGACCTTATCTTTAGATCACTTACTGACCCTTAATGATCTTTTTTATG
TCAGCTATAACCATGATTTAGGTGGTGGCGATGCGGGTAAACGTGGTACAGAGGGCTTTTATACCAGTTACACCATTCCT
TTTGATTATTGGTTACTTACCAGCAGTTACAGCAAATCTAACTACAATCAAACTGTAGCAGGTGCCAGTCAAAGCTATGA
ATATAGTGGTAAAAGTGAACTCATTGGCCTTGATTTGTCACGAGTGATTTATCGCGATGCACACCGCAAAACCACACTTG
GATTTGGCGGCTGGTATCGAGAATCACGCAATTACATTGAAGATGTTGAAGTTGAAGTTCAGCGCCGAAAAACAGCAGGC
TGGAAAGCCATGCTGGATCATACCGAATATTTTTCTAATGCGACTTTAAGCGGCAATTTGACCTACAAGCGCGGTACAGG
CTGGCTGGGTGCAATGCGTGCGCCAGAAGAAGACTTTGACGAAGCTTTTACCCGAGTGGGCATTTTACAAGCCAATGCCA
GTTTACAGGTGCCGTTTAAAGTCGGTGCACAGAATCTGCAATATACCGCTGAATGGCGTATGCAAAGTAGTAACAAACCT
TTAACCCCCCAAGACCGTTTCTCGATTGGTAACCGCTATACCGTACGTGGCTTTGATGGCGAACAAACCTTATTGGCAGA
TCAAGGTTTTCTGGTTCGTAATGAAATCAGCGGTTCGATATTTGGTAAACCACATTATTGGTATGCCGGCATTGATTATG
GCGAAGTCGGTGGGCGTACTGCTTATCAGCCTAATCCATTGCCAGGTACAAGCTTGCTGGGCAGTGTAGTGGGTTTACGT
GGCCAGATTGCGCCACTACGAATGAGTTACGACGTATTTGTGGGTGCCCCACTTAAAAAGCCAGATAATTTTAGAACAGA
CCATTACACCACAGGCTTTAGCCTGAACTGGGGCTACTGA

Upstream 100 bases:

>100_bases
CACTAGACCCGTCTGTATAAAAAATAAGAGTGACATATTTACAAAAATAAAAACCTTGTTATGATTTGTTAACTAGTTAT
CATTTATTTTAATAAATCCA

Downstream 100 bases:

>100_bases
TGTGTAGCTGAATCGTTTGAGCAAGATTTTCATTTTTTCTCGTTAATGAGATTGCAATACATAACAAAATTTAGAGTAAA
AGCACATGAATAAGAATCGC

Product: hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MKITIVDCKVILKKTALCLGVCSSIHGLVHAADLTQQEITEQQRRDAQKNMADNQIRQQQRDDALQKQIQPEVNVNLGPQ
NAKLQAQQLQYLRSHSESPCFEIKDIHLQGEKAEHFLFALNEITQGTHNIIGRCLGVQGLNQALDLVQNRIISAGYVTSR
VLLPAQNIASGQLKIAVIAGRVDHVKFAEGTSSRAHKINALPIKSGDLLNLHDLEQGLENFKRVPTVEADFKIQPAENNN
TPGYSDVILAWQQSKPYRINLSLDDSGSDSTGKYQGTATLSLDHLLTLNDLFYVSYNHDLGGGDAGKRGTEGFYTSYTIP
FDYWLLTSSYSKSNYNQTVAGASQSYEYSGKSELIGLDLSRVIYRDAHRKTTLGFGGWYRESRNYIEDVEVEVQRRKTAG
WKAMLDHTEYFSNATLSGNLTYKRGTGWLGAMRAPEEDFDEAFTRVGILQANASLQVPFKVGAQNLQYTAEWRMQSSNKP
LTPQDRFSIGNRYTVRGFDGEQTLLADQGFLVRNEISGSIFGKPHYWYAGIDYGEVGGRTAYQPNPLPGTSLLGSVVGLR
GQIAPLRMSYDVFVGAPLKKPDNFRTDHYTTGFSLNWGY

Sequences:

>Translated_599_residues
MKITIVDCKVILKKTALCLGVCSSIHGLVHAADLTQQEITEQQRRDAQKNMADNQIRQQQRDDALQKQIQPEVNVNLGPQ
NAKLQAQQLQYLRSHSESPCFEIKDIHLQGEKAEHFLFALNEITQGTHNIIGRCLGVQGLNQALDLVQNRIISAGYVTSR
VLLPAQNIASGQLKIAVIAGRVDHVKFAEGTSSRAHKINALPIKSGDLLNLHDLEQGLENFKRVPTVEADFKIQPAENNN
TPGYSDVILAWQQSKPYRINLSLDDSGSDSTGKYQGTATLSLDHLLTLNDLFYVSYNHDLGGGDAGKRGTEGFYTSYTIP
FDYWLLTSSYSKSNYNQTVAGASQSYEYSGKSELIGLDLSRVIYRDAHRKTTLGFGGWYRESRNYIEDVEVEVQRRKTAG
WKAMLDHTEYFSNATLSGNLTYKRGTGWLGAMRAPEEDFDEAFTRVGILQANASLQVPFKVGAQNLQYTAEWRMQSSNKP
LTPQDRFSIGNRYTVRGFDGEQTLLADQGFLVRNEISGSIFGKPHYWYAGIDYGEVGGRTAYQPNPLPGTSLLGSVVGLR
GQIAPLRMSYDVFVGAPLKKPDNFRTDHYTTGFSLNWGY
>Mature_599_residues
MKITIVDCKVILKKTALCLGVCSSIHGLVHAADLTQQEITEQQRRDAQKNMADNQIRQQQRDDALQKQIQPEVNVNLGPQ
NAKLQAQQLQYLRSHSESPCFEIKDIHLQGEKAEHFLFALNEITQGTHNIIGRCLGVQGLNQALDLVQNRIISAGYVTSR
VLLPAQNIASGQLKIAVIAGRVDHVKFAEGTSSRAHKINALPIKSGDLLNLHDLEQGLENFKRVPTVEADFKIQPAENNN
TPGYSDVILAWQQSKPYRINLSLDDSGSDSTGKYQGTATLSLDHLLTLNDLFYVSYNHDLGGGDAGKRGTEGFYTSYTIP
FDYWLLTSSYSKSNYNQTVAGASQSYEYSGKSELIGLDLSRVIYRDAHRKTTLGFGGWYRESRNYIEDVEVEVQRRKTAG
WKAMLDHTEYFSNATLSGNLTYKRGTGWLGAMRAPEEDFDEAFTRVGILQANASLQVPFKVGAQNLQYTAEWRMQSSNKP
LTPQDRFSIGNRYTVRGFDGEQTLLADQGFLVRNEISGSIFGKPHYWYAGIDYGEVGGRTAYQPNPLPGTSLLGSVVGLR
GQIAPLRMSYDVFVGAPLKKPDNFRTDHYTTGFSLNWGY

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 66790; Mature: 66790

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIVDCKVILKKTALCLGVCSSIHGLVHAADLTQQEITEQQRRDAQKNMADNQIRQQQ
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
RDDALQKQIQPEVNVNLGPQNAKLQAQQLQYLRSHSESPCFEIKDIHLQGEKAEHFLFAL
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHH
NEITQGTHNIIGRCLGVQGLNQALDLVQNRIISAGYVTSRVLLPAQNIASGQLKIAVIAG
HHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCEEEEEEEC
RVDHVKFAEGTSSRAHKINALPIKSGDLLNLHDLEQGLENFKRVPTVEADFKIQPAENNN
CCCEEEECCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
TPGYSDVILAWQQSKPYRINLSLDDSGSDSTGKYQGTATLSLDHLLTLNDLFYVSYNHDL
CCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCEEEEEEHHHEEEEEEEEEEEECCCC
GGGDAGKRGTEGFYTSYTIPFDYWLLTSSYSKSNYNQTVAGASQSYEYSGKSELIGLDLS
CCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCEEEECCHH
RVIYRDAHRKTTLGFGGWYRESRNYIEDVEVEVQRRKTAGWKAMLDHTEYFSNATLSGNL
HHHHHHCCCCEEECCCCHHHHHCCCHHHHHHHEEHHHCCCHHHHHHHHHHHCCCEEECCE
TYKRGTGWLGAMRAPEEDFDEAFTRVGILQANASLQVPFKVGAQNLQYTAEWRMQSSNKP
EEECCCCCEECCCCCHHHHHHHHHHHEEEEECCEEEEEHHHCCCCCEEEEEEEECCCCCC
LTPQDRFSIGNRYTVRGFDGEQTLLADQGFLVRNEISGSIFGKPHYWYAGIDYGEVGGRT
CCCHHHHCCCCEEEEEECCCCCEEEECCCEEEEECCCCCEECCCCEEEECCCHHCCCCCC
AYQPNPLPGTSLLGSVVGLRGQIAPLRMSYDVFVGAPLKKPDNFRTDHYTTGFSLNWGY
CCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCEECCEEEECCC
>Mature Secondary Structure
MKITIVDCKVILKKTALCLGVCSSIHGLVHAADLTQQEITEQQRRDAQKNMADNQIRQQQ
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
RDDALQKQIQPEVNVNLGPQNAKLQAQQLQYLRSHSESPCFEIKDIHLQGEKAEHFLFAL
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHH
NEITQGTHNIIGRCLGVQGLNQALDLVQNRIISAGYVTSRVLLPAQNIASGQLKIAVIAG
HHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCEEEEEEEC
RVDHVKFAEGTSSRAHKINALPIKSGDLLNLHDLEQGLENFKRVPTVEADFKIQPAENNN
CCCEEEECCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
TPGYSDVILAWQQSKPYRINLSLDDSGSDSTGKYQGTATLSLDHLLTLNDLFYVSYNHDL
CCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCEEEEEEHHHEEEEEEEEEEEECCCC
GGGDAGKRGTEGFYTSYTIPFDYWLLTSSYSKSNYNQTVAGASQSYEYSGKSELIGLDLS
CCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCEECCCCCCCCCCCCCEEEECCHH
RVIYRDAHRKTTLGFGGWYRESRNYIEDVEVEVQRRKTAGWKAMLDHTEYFSNATLSGNL
HHHHHHCCCCEEECCCCHHHHHCCCHHHHHHHEEHHHCCCHHHHHHHHHHHCCCEEECCE
TYKRGTGWLGAMRAPEEDFDEAFTRVGILQANASLQVPFKVGAQNLQYTAEWRMQSSNKP
EEECCCCCEECCCCCHHHHHHHHHHHEEEEECCEEEEEHHHCCCCCEEEEEEEECCCCCC
LTPQDRFSIGNRYTVRGFDGEQTLLADQGFLVRNEISGSIFGKPHYWYAGIDYGEVGGRT
CCCHHHHCCCCEEEEEECCCCCEEEECCCEEEEECCCCCEECCCCEEEECCCHHCCCCCC
AYQPNPLPGTSLLGSVVGLRGQIAPLRMSYDVFVGAPLKKPDNFRTDHYTTGFSLNWGY
CCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCEECCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]