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The map label for this gene is uppP2

Identifier: 50084122

GI number: 50084122

Start: 895387

End: 896244

Strand: Direct

Name: uppP2

Synonym: ACIAD0914

Alternate gene names: 50084122

Gene position: 895387-896244 (Clockwise)

Preceding gene: 50084121

Following gene: 50084126

Centisome position: 24.88

GC content: 42.54

Gene sequence:

>858_bases
ATGAGTCACGCCATGGATCTGTTGCATGTTTTTATTTTAGCTGTTATTCAGGGATTAGCTGAATTACTACCCGTTTCGAG
TTCTGCGCATGTAATTTTGGCAGAAAAGCTGATGGGGTTTGATCCTTCAGCACCCAATATGACATTTTTATTGGTTATGC
TGCATACGGGAACCATGTTTGCCGTTATTGTGTATTTTTGGCATTCGTGGAAGAAAACTTACTTTTTTGATTGGCAGTCA
TTTAAACAGCGTGCATGGTATGTGTTACTGGCAACCGCGATTACGGGCGTACTTGGGCTGTTATTGCAATCGCTCATTAA
GCATGTGTTCTTTGGCGGAGTGAGCAGCTTTGAAATTGAGCATTTATTTAGTAATTCAAAACTGATGGCTGCGGCATTGG
CTGCGGCAGGAATTTTAATTATTTTGTCTTCTCGTTTAGATCGCGGACAGCAAGGCGATATCCGTTTACCAAGCGCTATG
ATTATTGGCGCTGTGCAGGCATTGTGTCTACCTTTTCGTGGTTTTTCTCGTTCTGGTGCGACTATTTCAACGGGACTATT
TTTAGGTATTTCCCGTCAAAAAGCAGAAGAATTCAGCTTCGCTTTGGCAGTGGTGCTTACTCCTGCTGTGATTGTAAAAG
AACTTGTACGCTTATTGCATGCTCAACACGCAACGACAGGAGCAACGCATTTGGCGTTAGGGAGCCTGCTTTTGCCGAGT
ATATTTGGAATGGTATTTAGTTTTTTGACTGGTTTATTGGCACTTAAATGGCTTTCAGCATGGCTCGAGCATGGTCGTTG
GTATTTATTTGGTATTTACTGTCTGGCATTTTCAGGTGTCGTTCTGACTTTGGCTTAA

Upstream 100 bases:

>100_bases
ATGATTTTATTTAAAAAGGGATATGATTTATTTCTAAAAAATTTTACGCTTTTTAATCTGTTCTTAATGGCATCTGCGTA
TATAAGCTGCAATAGCATAT

Downstream 100 bases:

>100_bases
ATACTCAAGCTAAATAATTACGAGGGAAATTTATGTTCCCTCGTTTAAAAATTAAAAACTCTTAATTAGCAAATTGATTC
ATCATGCGGTTTGATTTAAA

Product: undecaprenol kinase 2 (bacitracin resistance protein 2)

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSHAMDLLHVFILAVIQGLAELLPVSSSAHVILAEKLMGFDPSAPNMTFLLVMLHTGTMFAVIVYFWHSWKKTYFFDWQS
FKQRAWYVLLATAITGVLGLLLQSLIKHVFFGGVSSFEIEHLFSNSKLMAAALAAAGILIILSSRLDRGQQGDIRLPSAM
IIGAVQALCLPFRGFSRSGATISTGLFLGISRQKAEEFSFALAVVLTPAVIVKELVRLLHAQHATTGATHLALGSLLLPS
IFGMVFSFLTGLLALKWLSAWLEHGRWYLFGIYCLAFSGVVLTLA

Sequences:

>Translated_285_residues
MSHAMDLLHVFILAVIQGLAELLPVSSSAHVILAEKLMGFDPSAPNMTFLLVMLHTGTMFAVIVYFWHSWKKTYFFDWQS
FKQRAWYVLLATAITGVLGLLLQSLIKHVFFGGVSSFEIEHLFSNSKLMAAALAAAGILIILSSRLDRGQQGDIRLPSAM
IIGAVQALCLPFRGFSRSGATISTGLFLGISRQKAEEFSFALAVVLTPAVIVKELVRLLHAQHATTGATHLALGSLLLPS
IFGMVFSFLTGLLALKWLSAWLEHGRWYLFGIYCLAFSGVVLTLA
>Mature_284_residues
SHAMDLLHVFILAVIQGLAELLPVSSSAHVILAEKLMGFDPSAPNMTFLLVMLHTGTMFAVIVYFWHSWKKTYFFDWQSF
KQRAWYVLLATAITGVLGLLLQSLIKHVFFGGVSSFEIEHLFSNSKLMAAALAAAGILIILSSRLDRGQQGDIRLPSAMI
IGAVQALCLPFRGFSRSGATISTGLFLGISRQKAEEFSFALAVVLTPAVIVKELVRLLHAQHATTGATHLALGSLLLPSI
FGMVFSFLTGLLALKWLSAWLEHGRWYLFGIYCLAFSGVVLTLA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=218, Percent_Identity=34.8623853211009, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_ACIAD (Q6FDP8)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045632.1
- STRING:   Q6FDP8
- GeneID:   2878759
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0914
- NMPDR:   fig|62977.3.peg.914
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   MFAVIVY
- ProtClustDB:   CLSK2462973
- BioCyc:   ASP62977:ACIAD0914-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 31186; Mature: 31055

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16dab8b8)-; HASH(0x165e1490)-; HASH(0x16358f30)-; HASH(0x16b9b420)-; HASH(0x16b37cdc)-; HASH(0x16f1136c)-; HASH(0x172b6d24)-; HASH(0x16980278)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAMDLLHVFILAVIQGLAELLPVSSSAHVILAEKLMGFDPSAPNMTFLLVMLHTGTMF
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AVIVYFWHSWKKTYFFDWQSFKQRAWYVLLATAITGVLGLLLQSLIKHVFFGGVSSFEIE
HHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HLFSNSKLMAAALAAAGILIILSSRLDRGQQGDIRLPSAMIIGAVQALCLPFRGFSRSGA
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
TISTGLFLGISRQKAEEFSFALAVVLTPAVIVKELVRLLHAQHATTGATHLALGSLLLPS
EEEHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IFGMVFSFLTGLLALKWLSAWLEHGRWYLFGIYCLAFSGVVLTLA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECH
>Mature Secondary Structure 
SHAMDLLHVFILAVIQGLAELLPVSSSAHVILAEKLMGFDPSAPNMTFLLVMLHTGTMF
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AVIVYFWHSWKKTYFFDWQSFKQRAWYVLLATAITGVLGLLLQSLIKHVFFGGVSSFEIE
HHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HLFSNSKLMAAALAAAGILIILSSRLDRGQQGDIRLPSAMIIGAVQALCLPFRGFSRSGA
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
TISTGLFLGISRQKAEEFSFALAVVLTPAVIVKELVRLLHAQHATTGATHLALGSLLLPS
EEEHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IFGMVFSFLTGLLALKWLSAWLEHGRWYLFGIYCLAFSGVVLTLA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA