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The map label for this gene is mreB [H]

Identifier: 50084039

GI number: 50084039

Start: 814549

End: 815589

Strand: Direct

Name: mreB [H]

Synonym: ACIAD0825

Alternate gene names: 50084039

Gene position: 814549-815589 (Clockwise)

Preceding gene: 50084035

Following gene: 50084040

Centisome position: 22.64

GC content: 45.73

Gene sequence:

>1041_bases
GTGATTCTAAAACGACTAATTGGCTTGTTTTCGCCAGATCTAGCCATTGATTTAGGTACAGCAAATACACTTATTTATGC
ACCGGGCAGAGGCATTATATTAAATGAACCGACTGTTGTGGCCATTCGTCACAGTGGTTCGCAGAAAATTGTTGCTGCTG
TAGGTCTCGATGCTAAACAAATGCTAGGTCGTACGCCAGCGAATATTTCTGCAATTCGTCCCATGAAGGATGGCGTGATT
GCCGACTTTGAAGTCACAGAAACCATGCTGAACCAGTTTATTGGTAAAGTGCATGAAAAACGTTTATTTCCACCTGCACC
GCGTGTTGTGGTGTGCGTGCCGTGTAAATCGACACTGGTTGAGCGCCGTGCGATTCGTGAAGCCGTATTTAATGCAGGCG
CACGTGATGTCCGTTTGATTGAAGAGCCGATGGCTGCTGCAATTGGTGCAGGTATGCCTGTAGAACAAGCCTGCGGTTCA
ATGGTAGTTGACGTGGGTGGTGGTACTACTGAAATTGCGATCATCTCGCTTCAAGGCTGTGTCTATGCAGATTCTTTGCG
TATTGGTGGCGATGTATTTGATGAGCAAATCATTCATTATGTGCGTAAGGCACATGGCTGTGTGATTGGTGAGACGACGG
CTGAAAATATCAAGAAAGAAGTGGGTATGGCGATTGCCGATGACACTAAGCTTGAGATTGAAGTTCGCGGTCGTAATTTG
GCAGAAGGTGTACCACGCTCAATTACTGTTACATCGGATGAAGTGATGCAAGCGATTGCAGATCCATTACAAAGTATTGT
CAGTGCTGTCAAATCTGCACTTGAACAAACGCCGCCAGAATTGTCATCAGATATCGCAGAGCGCGGTATTGTCTTAACTG
GTGGTGGTGCATTATTACGTAACCTCGACAAGTTATTGGCGCAAGAAACTGGTTTACCTGTAGTGGTTGCAGAAGATCCA
CTGACTTGCGTGACTCGTGGTGGTGGCAAGGTGCTTGAATTCTTTGATAATCCAAATCACGATATGCTTTTTGTTGGCTA
A

Upstream 100 bases:

>100_bases
AAATAATGTGGCTTATAATAAGCGATTGACTTGTTCAAAGCATCACATTTAGTTAAAGTTGCCAACTTGCGTCCACATAA
AGTTTAACTGGGAACGACCC

Downstream 100 bases:

>100_bases
TTTATTAAGGACGGGGCGGTGCAACCGAATCTTTTTTCAAGACAACCGCCATCTTTTCGCTCTTTTATAATTGCGGTCAT
TACAAGTCTGGTAGTGCTAT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MILKRLIGLFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQMLGRTPANISAIRPMKDGVI
ADFEVTETMLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLVERRAIREAVFNAGARDVRLIEEPMAAAIGAGMPVEQACGS
MVVDVGGGTTEIAIISLQGCVYADSLRIGGDVFDEQIIHYVRKAHGCVIGETTAENIKKEVGMAIADDTKLEIEVRGRNL
AEGVPRSITVTSDEVMQAIADPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLRNLDKLLAQETGLPVVVAEDP
LTCVTRGGGKVLEFFDNPNHDMLFVG

Sequences:

>Translated_346_residues
MILKRLIGLFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQMLGRTPANISAIRPMKDGVI
ADFEVTETMLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLVERRAIREAVFNAGARDVRLIEEPMAAAIGAGMPVEQACGS
MVVDVGGGTTEIAIISLQGCVYADSLRIGGDVFDEQIIHYVRKAHGCVIGETTAENIKKEVGMAIADDTKLEIEVRGRNL
AEGVPRSITVTSDEVMQAIADPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLRNLDKLLAQETGLPVVVAEDP
LTCVTRGGGKVLEFFDNPNHDMLFVG
>Mature_346_residues
MILKRLIGLFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQMLGRTPANISAIRPMKDGVI
ADFEVTETMLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLVERRAIREAVFNAGARDVRLIEEPMAAAIGAGMPVEQACGS
MVVDVGGGTTEIAIISLQGCVYADSLRIGGDVFDEQIIHYVRKAHGCVIGETTAENIKKEVGMAIADDTKLEIEVRGRNL
AEGVPRSITVTSDEVMQAIADPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLRNLDKLLAQETGLPVVVAEDP
LTCVTRGGGKVLEFFDNPNHDMLFVG

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=355, Percent_Identity=24.2253521126761, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI16507237, Length=355, Percent_Identity=24.2253521126761, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI48928056, Length=172, Percent_Identity=27.906976744186, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87082236, Length=344, Percent_Identity=68.3139534883721, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1788875, Length=389, Percent_Identity=23.6503856041131, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17568549, Length=304, Percent_Identity=25.9868421052632, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534771, Length=333, Percent_Identity=26.4264264264264, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319972, Length=298, Percent_Identity=27.1812080536913, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324120, Length=298, Percent_Identity=27.1812080536913, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322426, Length=230, Percent_Identity=25.2173913043478, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36779; Mature: 36779

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKRLIGLFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQ
CHHHHHHHHCCCCCEEEECCCCEEEEECCCEEEECCCEEEEEEECCCCEEEEEECCCHHH
MLGRTPANISAIRPMKDGVIADFEVTETMLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLV
HHCCCCCCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHH
ERRAIREAVFNAGARDVRLIEEPMAAAIGAGMPVEQACGSMVVDVGGGTTEIAIISLQGC
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEEECCCCCEEEEEEEECCE
VYADSLRIGGDVFDEQIIHYVRKAHGCVIGETTAENIKKEVGMAIADDTKLEIEVRGRNL
EEECCEECCCHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHCCEEECCCEEEEEECCCCH
AEGVPRSITVTSDEVMQAIADPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLR
HCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCHHHHH
NLDKLLAQETGLPVVVAEDPLTCVTRGGGKVLEFFDNPNHDMLFVG
HHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEECCCCCCCEEEEC
>Mature Secondary Structure
MILKRLIGLFSPDLAIDLGTANTLIYAPGRGIILNEPTVVAIRHSGSQKIVAAVGLDAKQ
CHHHHHHHHCCCCCEEEECCCCEEEEECCCEEEECCCEEEEEEECCCCEEEEEECCCHHH
MLGRTPANISAIRPMKDGVIADFEVTETMLNQFIGKVHEKRLFPPAPRVVVCVPCKSTLV
HHCCCCCCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHH
ERRAIREAVFNAGARDVRLIEEPMAAAIGAGMPVEQACGSMVVDVGGGTTEIAIISLQGC
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCEEEECCCCCEEEEEEEECCE
VYADSLRIGGDVFDEQIIHYVRKAHGCVIGETTAENIKKEVGMAIADDTKLEIEVRGRNL
EEECCEECCCHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHCCEEECCCEEEEEECCCCH
AEGVPRSITVTSDEVMQAIADPLQSIVSAVKSALEQTPPELSSDIAERGIVLTGGGALLR
HCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCHHHHH
NLDKLLAQETGLPVVVAEDPLTCVTRGGGKVLEFFDNPNHDMLFVG
HHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]