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The map label for this gene is pcbC [H]

Identifier: 50083980

GI number: 50083980

Start: 748702

End: 749652

Strand: Direct

Name: pcbC [H]

Synonym: ACIAD0764

Alternate gene names: 50083980

Gene position: 748702-749652 (Clockwise)

Preceding gene: 50083977

Following gene: 50083981

Centisome position: 20.81

GC content: 39.64

Gene sequence:

>951_bases
GTGACCCAGCATATTCCGATCATTTCTATTTCAGGTTTGTTTAGTCCATTGCTTGAAGATCGCTTACAGGTTGCCATGCA
AATGAAACAGGCATGTGAAGATAACGGCTTCTTTTATATTGCAGATCATGGTGTTTCTAAAAACTTACAACAGAAAGTAT
TTGAACAAAGTCGGCAATTTTTTGATTTACCGACAAATGAAAAAGAAAAAATTCATAAGAAAAACTCGATTGCCAATCGT
GGTTATGAACCGTTAAAAAATCAGACGCTAGAAGCAGGAACACCTGCTGACTTAAAAGAAGGTTTCTATGCTGGACGTGA
ATATGCGTTGGACAGTCAGGCCGTATTAAACAAAAGATTTAACCACGGGCCAAATCAATGGCCCGAACAATTTCCTGAAT
TTGAATCGACCATGCAGCATTATCAGGCTGAACTTGAAGTATTGGCTAAACATCTGATGCGAGGTTTGGCGCTTTCGCTT
AATTTAGATGAAAACTATTTTGATGACTTTTGTCAGGATTCTTTGGTGACTTTACGGCTACTTCATTATCCGCCACAACC
TGCCAATCCTGAGCCAAATGAAAAAGGTTGCGGAGCACATACCGATTTTGGTGCATTAACTTTATTACTCCAAGATCAAC
AAGGAGGCTTGCAGGTATGGGATAAACATACCGAAAGCTGGATTGATGCACCTCCAATTGAAGGAACATACGTAATTAAT
CTAGGTGATTTGATTGCTCGCTGGACCAACAATCATTACAAATCGACCGTTCATCGAGTCATTAATAAATCTGGCAAACA
ACGCTACTCAGTTCCATTTTTCTTTGGTGGAAATCCTGATTATCTGGTCAAATGTCTCCCAGATTGCATGTCAGAAAGTG
AGCCATCCTTATTTGTACCTACCACAGTTGAACAGCATCATATCGAAATGTATCGGAGAACCTATGGCTAA

Upstream 100 bases:

>100_bases
GAATTTTGAAATAACGAAATTGATATAAACCTGAACGATTTATTTTGGCTGGCATGTGAATTGCCTTCTCGATATAACAT
TTAAAAAAAGGTAATACATC

Downstream 100 bases:

>100_bases
GCATATTGTATTGGTACATGGCGCTTGGCAGGGCAGTTGGTCATTTGATTTGATCAAGCCATGGTTGCAGCAAAAAGGTT
GGACAGTACATGCAGTTGAT

Product: oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTQHIPIISISGLFSPLLEDRLQVAMQMKQACEDNGFFYIADHGVSKNLQQKVFEQSRQFFDLPTNEKEKIHKKNSIANR
GYEPLKNQTLEAGTPADLKEGFYAGREYALDSQAVLNKRFNHGPNQWPEQFPEFESTMQHYQAELEVLAKHLMRGLALSL
NLDENYFDDFCQDSLVTLRLLHYPPQPANPEPNEKGCGAHTDFGALTLLLQDQQGGLQVWDKHTESWIDAPPIEGTYVIN
LGDLIARWTNNHYKSTVHRVINKSGKQRYSVPFFFGGNPDYLVKCLPDCMSESEPSLFVPTTVEQHHIEMYRRTYG

Sequences:

>Translated_316_residues
MTQHIPIISISGLFSPLLEDRLQVAMQMKQACEDNGFFYIADHGVSKNLQQKVFEQSRQFFDLPTNEKEKIHKKNSIANR
GYEPLKNQTLEAGTPADLKEGFYAGREYALDSQAVLNKRFNHGPNQWPEQFPEFESTMQHYQAELEVLAKHLMRGLALSL
NLDENYFDDFCQDSLVTLRLLHYPPQPANPEPNEKGCGAHTDFGALTLLLQDQQGGLQVWDKHTESWIDAPPIEGTYVIN
LGDLIARWTNNHYKSTVHRVINKSGKQRYSVPFFFGGNPDYLVKCLPDCMSESEPSLFVPTTVEQHHIEMYRRTYG
>Mature_315_residues
TQHIPIISISGLFSPLLEDRLQVAMQMKQACEDNGFFYIADHGVSKNLQQKVFEQSRQFFDLPTNEKEKIHKKNSIANRG
YEPLKNQTLEAGTPADLKEGFYAGREYALDSQAVLNKRFNHGPNQWPEQFPEFESTMQHYQAELEVLAKHLMRGLALSLN
LDENYFDDFCQDSLVTLRLLHYPPQPANPEPNEKGCGAHTDFGALTLLLQDQQGGLQVWDKHTESWIDAPPIEGTYVINL
GDLIARWTNNHYKSTVHRVINKSGKQRYSVPFFFGGNPDYLVKCLPDCMSESEPSLFVPTTVEQHHIEMYRRTYG

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=306, Percent_Identity=26.4705882352941, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI85816264, Length=290, Percent_Identity=26.551724137931, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 36224; Mature: 36093

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHIPIISISGLFSPLLEDRLQVAMQMKQACEDNGFFYIADHGVSKNLQQKVFEQSRQF
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
FDLPTNEKEKIHKKNSIANRGYEPLKNQTLEAGTPADLKEGFYAGREYALDSQAVLNKRF
CCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCHHHCCCHHHHHHHHH
NHGPNQWPEQFPEFESTMQHYQAELEVLAKHLMRGLALSLNLDENYFDDFCQDSLVTLRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHH
LHYPPQPANPEPNEKGCGAHTDFGALTLLLQDQQGGLQVWDKHTESWIDAPPIEGTYVIN
HHCCCCCCCCCCCCCCCCCCCCHHEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEE
LGDLIARWTNNHYKSTVHRVINKSGKQRYSVPFFFGGNPDYLVKCLPDCMSESEPSLFVP
HHHHHHHHHCCHHHHHHHHHHHCCCCCEECCCEEECCCHHHHHHHHHHHHCCCCCCEEEC
TTVEQHHIEMYRRTYG
CCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQHIPIISISGLFSPLLEDRLQVAMQMKQACEDNGFFYIADHGVSKNLQQKVFEQSRQF
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
FDLPTNEKEKIHKKNSIANRGYEPLKNQTLEAGTPADLKEGFYAGREYALDSQAVLNKRF
CCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCHHHCCCHHHHHHHHH
NHGPNQWPEQFPEFESTMQHYQAELEVLAKHLMRGLALSLNLDENYFDDFCQDSLVTLRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHH
LHYPPQPANPEPNEKGCGAHTDFGALTLLLQDQQGGLQVWDKHTESWIDAPPIEGTYVIN
HHCCCCCCCCCCCCCCCCCCCCHHEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEE
LGDLIARWTNNHYKSTVHRVINKSGKQRYSVPFFFGGNPDYLVKCLPDCMSESEPSLFVP
HHHHHHHHHCCHHHHHHHHHHHCCCCCEECCCEEECCCHHHHHHHHHHHHCCCCCCEEEC
TTVEQHHIEMYRRTYG
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3130293 [H]