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The map label for this gene is ygfU [H]

Identifier: 50083979

GI number: 50083979

Start: 747161

End: 748582

Strand: Reverse

Name: ygfU [H]

Synonym: ACIAD0762

Alternate gene names: 50083979

Gene position: 748582-747161 (Counterclockwise)

Preceding gene: 50083982

Following gene: 50083978

Centisome position: 20.8

GC content: 41.7

Gene sequence:

>1422_bases
ATGCGTGGCATATATGTTGCAATTTTTCTTGAAAATCTATCAAGAATAGAAGTAAGCGCTATGAATACAAAAGCAACCTC
ACCTGAACATGAACACCTAGGACTCACCAAAAATTTGACCTATGGTTTCCAGCATGTCCTTACCATGTACGGCGGGTTAA
TCGCAGCGCCGTTGGTCGTGGGCCTTGGTATTGGTCTATCCCAAGCTGATATTGGTCTTTTGATTACAGCCTCTATTTTG
GTGGCAGGCTTGGCAACATTATTGCAAACCCTTGGCTTTAAGTGGTTTGGTTCACGTTTACCTATTGTTCAAGGAACTTC
TTTTGCGGCTGTAGCAAGTATGATCGCAATTGGTGCAAATGGAGGCAGCTTCCAGTCCATTCTTGGTGCAATTATAGTCA
GTTCCATTTTTGGAATTATTGTTGCACCATTTTTTTCCAAAATTGTTCGCTTTTTCCCCCCTATTGTGACAGGTTCAATT
ATTGCAATTATTGGTATTTCACTTCTACCTGTTGCCATTCGCTGGATCATGGGTGGTAATCCTAAAGCACCCAACTGGGG
TTCTTTGGAAAATTTAGGCTTGGCTGGCATTACCTTAGTCTTTTTACTTTTACTGACCAAGTTTGGCTCAACATCTATCA
AACGATTAGCGGTATTACTTTCCATTATATTTGGGGCAATTGTTGCATTTGCTTTCGGTTTAGCAGATTTTTCTAAAGTG
AGTCAGGGCGCATGGATGGCTCTACCAAATATTTTGGGCTTTGGTATGCCTGTGTTTGAATGGCCTGCCATTCTATCGAT
GTGTATTGTCACCTTAGTAATTTTAACAGAAACCACAGCCAGCTTACTCGCAATTGGAGAAATCGTAGAAACCAAGGTGG
ATAATCACCGCATTGCAGATGGTTTACGTGCCGATATGCTATCTTCTGCACTAGCCCCATTTTTCGGCGCATTTATGCAA
TGTGCTTTTGTACAAAATGTAGGGCTCGTGGCTATTACAGGTGTAAAAAGCCGTTTTGTAGTTGCAACAGCAGGTGGAAT
TTTAGTGGTACTGGGCTTACTTCCTGTGTTTGGTCGTCTGGTCGCATCCATTCCAATGCCTGTTTTAGGCGGTGCAGGAT
TGGTGCTTTTTGGTAGTGTTGCCGTGAGTGGTATTCGAACATTGTCTAAAGTCGACTATCAACTACAATCCAACATGATT
ATTGTGGCAGTATCACTAGGGGCTGGTTTGATTCCATTAATTAGCCCAGAATTCTTTCATTCTATGCCTGGTGCCGTACA
AACCCTGTTCCATTCTGGCATCAGTATTACTTGTATTATGGCATTGTTACTTAACCTGTTCTTTAACCATTTAAATTTTG
GAAAAAAGACAGTTTCTGAAGGATTAACCAAGCCTTCAGCGACAGCACAAAACCATCTTTAG

Upstream 100 bases:

>100_bases
AATGTTATATCGAGAAGGCAATTCACATGCCAGCCAAAATAAATCGTTCAGGTTTATATCAATTTCGTTATTTCAAAATT
CAGGAAACATGAAAGACCGA

Downstream 100 bases:

>100_bases
AAATGAATCCTGCTTTGCCCCAAGCCAAACAGTTTTAATGTTTGGCTTTTTCAATATGACGATTAATACACATTAATAGA
TCAATCTAATCTGATTATCC

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MRGIYVAIFLENLSRIEVSAMNTKATSPEHEHLGLTKNLTYGFQHVLTMYGGLIAAPLVVGLGIGLSQADIGLLITASIL
VAGLATLLQTLGFKWFGSRLPIVQGTSFAAVASMIAIGANGGSFQSILGAIIVSSIFGIIVAPFFSKIVRFFPPIVTGSI
IAIIGISLLPVAIRWIMGGNPKAPNWGSLENLGLAGITLVFLLLLTKFGSTSIKRLAVLLSIIFGAIVAFAFGLADFSKV
SQGAWMALPNILGFGMPVFEWPAILSMCIVTLVILTETTASLLAIGEIVETKVDNHRIADGLRADMLSSALAPFFGAFMQ
CAFVQNVGLVAITGVKSRFVVATAGGILVVLGLLPVFGRLVASIPMPVLGGAGLVLFGSVAVSGIRTLSKVDYQLQSNMI
IVAVSLGAGLIPLISPEFFHSMPGAVQTLFHSGISITCIMALLLNLFFNHLNFGKKTVSEGLTKPSATAQNHL

Sequences:

>Translated_473_residues
MRGIYVAIFLENLSRIEVSAMNTKATSPEHEHLGLTKNLTYGFQHVLTMYGGLIAAPLVVGLGIGLSQADIGLLITASIL
VAGLATLLQTLGFKWFGSRLPIVQGTSFAAVASMIAIGANGGSFQSILGAIIVSSIFGIIVAPFFSKIVRFFPPIVTGSI
IAIIGISLLPVAIRWIMGGNPKAPNWGSLENLGLAGITLVFLLLLTKFGSTSIKRLAVLLSIIFGAIVAFAFGLADFSKV
SQGAWMALPNILGFGMPVFEWPAILSMCIVTLVILTETTASLLAIGEIVETKVDNHRIADGLRADMLSSALAPFFGAFMQ
CAFVQNVGLVAITGVKSRFVVATAGGILVVLGLLPVFGRLVASIPMPVLGGAGLVLFGSVAVSGIRTLSKVDYQLQSNMI
IVAVSLGAGLIPLISPEFFHSMPGAVQTLFHSGISITCIMALLLNLFFNHLNFGKKTVSEGLTKPSATAQNHL
>Mature_473_residues
MRGIYVAIFLENLSRIEVSAMNTKATSPEHEHLGLTKNLTYGFQHVLTMYGGLIAAPLVVGLGIGLSQADIGLLITASIL
VAGLATLLQTLGFKWFGSRLPIVQGTSFAAVASMIAIGANGGSFQSILGAIIVSSIFGIIVAPFFSKIVRFFPPIVTGSI
IAIIGISLLPVAIRWIMGGNPKAPNWGSLENLGLAGITLVFLLLLTKFGSTSIKRLAVLLSIIFGAIVAFAFGLADFSKV
SQGAWMALPNILGFGMPVFEWPAILSMCIVTLVILTETTASLLAIGEIVETKVDNHRIADGLRADMLSSALAPFFGAFMQ
CAFVQNVGLVAITGVKSRFVVATAGGILVVLGLLPVFGRLVASIPMPVLGGAGLVLFGSVAVSGIRTLSKVDYQLQSNMI
IVAVSLGAGLIPLISPEFFHSMPGAVQTLFHSGISITCIMALLLNLFFNHLNFGKKTVSEGLTKPSATAQNHL

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=457, Percent_Identity=24.945295404814, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI44680148, Length=452, Percent_Identity=24.3362831858407, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI40316845, Length=452, Percent_Identity=24.3362831858407, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI44680143, Length=461, Percent_Identity=24.7288503253796, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI87082181, Length=454, Percent_Identity=38.9867841409692, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1790087, Length=434, Percent_Identity=29.7235023041475, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87081818, Length=419, Percent_Identity=31.2649164677804, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87082178, Length=438, Percent_Identity=26.027397260274, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788843, Length=393, Percent_Identity=27.9898218829517, Blast_Score=115, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17558856, Length=440, Percent_Identity=23.1818181818182, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356175, Length=444, Percent_Identity=24.0990990990991, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49594; Mature: 49594

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGIYVAIFLENLSRIEVSAMNTKATSPEHEHLGLTKNLTYGFQHVLTMYGGLIAAPLVV
CCCEEEEHHHHHHHHHEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLGIGLSQADIGLLITASILVAGLATLLQTLGFKWFGSRLPIVQGTSFAAVASMIAIGAN
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHCCC
GGSFQSILGAIIVSSIFGIIVAPFFSKIVRFFPPIVTGSIIAIIGISLLPVAIRWIMGGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKAPNWGSLENLGLAGITLVFLLLLTKFGSTSIKRLAVLLSIIFGAIVAFAFGLADFSKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQGAWMALPNILGFGMPVFEWPAILSMCIVTLVILTETTASLLAIGEIVETKVDNHRIAD
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GLRADMLSSALAPFFGAFMQCAFVQNVGLVAITGVKSRFVVATAGGILVVLGLLPVFGRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
VASIPMPVLGGAGLVLFGSVAVSGIRTLSKVDYQLQSNMIIVAVSLGAGLIPLISPEFFH
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCHHHHH
SMPGAVQTLFHSGISITCIMALLLNLFFNHLNFGKKTVSEGLTKPSATAQNHL
HCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRGIYVAIFLENLSRIEVSAMNTKATSPEHEHLGLTKNLTYGFQHVLTMYGGLIAAPLVV
CCCEEEEHHHHHHHHHEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GLGIGLSQADIGLLITASILVAGLATLLQTLGFKWFGSRLPIVQGTSFAAVASMIAIGAN
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHCCC
GGSFQSILGAIIVSSIFGIIVAPFFSKIVRFFPPIVTGSIIAIIGISLLPVAIRWIMGGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PKAPNWGSLENLGLAGITLVFLLLLTKFGSTSIKRLAVLLSIIFGAIVAFAFGLADFSKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQGAWMALPNILGFGMPVFEWPAILSMCIVTLVILTETTASLLAIGEIVETKVDNHRIAD
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GLRADMLSSALAPFFGAFMQCAFVQNVGLVAITGVKSRFVVATAGGILVVLGLLPVFGRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
VASIPMPVLGGAGLVLFGSVAVSGIRTLSKVDYQLQSNMIIVAVSLGAGLIPLISPEFFH
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHCCHHHHH
SMPGAVQTLFHSGISITCIMALLLNLFFNHLNFGKKTVSEGLTKPSATAQNHL
HCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]