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The map label for this gene is rpe [H]

Identifier: 50083912

GI number: 50083912

Start: 675484

End: 676170

Strand: Direct

Name: rpe [H]

Synonym: ACIAD0685

Alternate gene names: 50083912

Gene position: 675484-676170 (Clockwise)

Preceding gene: 50083911

Following gene: 50083913

Centisome position: 18.77

GC content: 41.48

Gene sequence:

>687_bases
ATGTCCAAGCCTTATCTGATTGCGCCGTCTATTTTATCTGCTGATTTTGCCCGTTTGGGGGAGGATGTGGAACGTGTATT
GGAAGCAGGTGCAGATGTTGTGCATTTTGATGTAATGGATAACCATTATGTGCCGAATTTAACGTTTGGTGCAGGTGTAT
GTAAAGCATTGAAAAATTATGGTATTCAGGCACCTATTGACGTTCATCTGATGGTTTCACCTGTAGATCGTATGATTGGT
GACTTTCTGGATGCCGGTGCAGACATTATTACCTTTCATCCAGAGGCAACAGATCATATTGATCGTTCATTACAATTGAT
TAAGGCTGGTGGTGCGAAAGCTGGTCTAGTGTTCAATCCTGCAACACCGTTACATTATCTCGATTATGTACTTGATAAAG
TTGATCAGATTTTACTGATGAGTGTAAACCCTGGGTTTGGTGGACAAAAATTTATTCCAATGACACTTGAAAAGCTTCGT
CAGGCACGCAAGATGATTGATGCAAGTGGTTTAGATATCCGTTTAGAAGTAGATGGTGGTGTAGGGCCAGCAAATATTCG
TGAAATTGCGGAAGCTGGAGCAGATATGTTTGTTGCGGGTTCAGCAATTTTTGGCAAACCAGATTATAAAGCTGTGATTG
ATGAAATGCGTGTAGAGCTTGCCAAAGTTGGTTCACACACGGCATAA

Upstream 100 bases:

>100_bases
TTTTTGAAATGATTGATATTCGATTGATAGGCGACAAAGCAGCAGATCAATATGAGATTTGCTATACTTTAGACCAGTTT
ATTTCTTTGCCAGGTTCTTC

Downstream 100 bases:

>100_bases
GAGTAATCACTTTAATTTATATCAGGGTTGTGGATAACTTTGTTTATAACTATATGGATAACTGTGTTTATAAGTATATG
GATAAACTGGTGATAGAATA

Product: D-ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSKPYLIAPSILSADFARLGEDVERVLEAGADVVHFDVMDNHYVPNLTFGAGVCKALKNYGIQAPIDVHLMVSPVDRMIG
DFLDAGADIITFHPEATDHIDRSLQLIKAGGAKAGLVFNPATPLHYLDYVLDKVDQILLMSVNPGFGGQKFIPMTLEKLR
QARKMIDASGLDIRLEVDGGVGPANIREIAEAGADMFVAGSAIFGKPDYKAVIDEMRVELAKVGSHTA

Sequences:

>Translated_228_residues
MSKPYLIAPSILSADFARLGEDVERVLEAGADVVHFDVMDNHYVPNLTFGAGVCKALKNYGIQAPIDVHLMVSPVDRMIG
DFLDAGADIITFHPEATDHIDRSLQLIKAGGAKAGLVFNPATPLHYLDYVLDKVDQILLMSVNPGFGGQKFIPMTLEKLR
QARKMIDASGLDIRLEVDGGVGPANIREIAEAGADMFVAGSAIFGKPDYKAVIDEMRVELAKVGSHTA
>Mature_227_residues
SKPYLIAPSILSADFARLGEDVERVLEAGADVVHFDVMDNHYVPNLTFGAGVCKALKNYGIQAPIDVHLMVSPVDRMIGD
FLDAGADIITFHPEATDHIDRSLQLIKAGGAKAGLVFNPATPLHYLDYVLDKVDQILLMSVNPGFGGQKFIPMTLEKLRQ
ARKMIDASGLDIRLEVDGGVGPANIREIAEAGADMFVAGSAIFGKPDYKAVIDEMRVELAKVGSHTA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=218, Percent_Identity=43.1192660550459, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI219879828, Length=212, Percent_Identity=41.5094339622642, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=36.9047619047619, Blast_Score=100, Evalue=8e-22,
Organism=Escherichia coli, GI1789788, Length=224, Percent_Identity=77.6785714285714, Blast_Score=348, Evalue=2e-97,
Organism=Escherichia coli, GI1790523, Length=219, Percent_Identity=36.5296803652968, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=29.3838862559242, Blast_Score=100, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17552948, Length=219, Percent_Identity=39.7260273972603, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=235, Percent_Identity=38.7234042553192, Blast_Score=154, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=41.7061611374408, Blast_Score=163, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24575; Mature: 24443

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00074 GLFV_DEHYDROGENASE ; PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPYLIAPSILSADFARLGEDVERVLEAGADVVHFDVMDNHYVPNLTFGAGVCKALKNY
CCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
GIQAPIDVHLMVSPVDRMIGDFLDAGADIITFHPEATDHIDRSLQLIKAGGAKAGLVFNP
CCCCCCEEEEEECHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEECC
ATPLHYLDYVLDKVDQILLMSVNPGFGGQKFIPMTLEKLRQARKMIDASGLDIRLEVDGG
CCHHHHHHHHHHHHHHEEEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCC
VGPANIREIAEAGADMFVAGSAIFGKPDYKAVIDEMRVELAKVGSHTA
CCHHHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKPYLIAPSILSADFARLGEDVERVLEAGADVVHFDVMDNHYVPNLTFGAGVCKALKNY
CCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHC
GIQAPIDVHLMVSPVDRMIGDFLDAGADIITFHPEATDHIDRSLQLIKAGGAKAGLVFNP
CCCCCCEEEEEECHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEECC
ATPLHYLDYVLDKVDQILLMSVNPGFGGQKFIPMTLEKLRQARKMIDASGLDIRLEVDGG
CCHHHHHHHHHHHHHHEEEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCC
VGPANIREIAEAGADMFVAGSAIFGKPDYKAVIDEMRVELAKVGSHTA
CCHHHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]