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The map label for this gene is nudL [H]

Identifier: 50083903

GI number: 50083903

Start: 668987

End: 669601

Strand: Direct

Name: nudL [H]

Synonym: ACIAD0674

Alternate gene names: 50083903

Gene position: 668987-669601 (Clockwise)

Preceding gene: 50083901

Following gene: 50083904

Centisome position: 18.59

GC content: 42.44

Gene sequence:

>615_bases
GTGAAAGGAATGATTAAACAAGGATTAACACAGCAGTTGCAACAACGATTGCGTTTTGCAAAACGAACGCAACCTGCTGA
AGCAGCGGTGTTAATTGCCATCACTGATGAACATGATCCGAAGGTATTACTCACCAGACGTTCAACCCAGCTTACCAATC
ATGCAGGTGAAGTGTCTTTTCCTGGCGGTAAACGAGATATAGGCGATACCAGCAATATTGTGGTGGCATTGCGTGAGGCA
CAGGAAGAAACCGCGCTCAATCCGTTTGATGTCGAGTTGATTGGTGATCTTCCCATGCAACGTGCACGTAACGGAATGCG
GGTTAAACCTATTGTAGGACTGATTCCACCGCACGTTGATTTAAAGCCACAACCCACAGAAATAGATCGTATTTTTTTTG
CTTCATTGACTGAATTGATTGACGCGCCACCAACCCCTTACAAAGTACAATACATCAAACAAACGCTTTATTTCCCAAGT
TTACAGGTCGAAGATGAAGTGGTGTGGGGGTTAACGGCAAGAATGCTGATTTCTTTATTTAATTATGGATTGGGTTATCA
GAAAGAGTGGCCATTTTTACTGAATCCGCCTTCATTTTATCAAAGAAAATTTTAA

Upstream 100 bases:

>100_bases
GCTAAAGATAGCTCAGCATAACCGAATTTTTATTGTTTCGCATCATTTGTATACGACCTCCAGAAAATTCAGCTATGATG
GAAAAATAATAAAAAACTGA

Downstream 100 bases:

>100_bases
AGTCAGAATACAAGGAAAGATCATCATGATGTACAAGTTTCAAGGATATCATCCAAAAACAAAAACTCATCCATGGAATG
GGTGGATTGCAGGTAATGCA

Product: MutT/nudix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKGMIKQGLTQQLQQRLRFAKRTQPAEAAVLIAITDEHDPKVLLTRRSTQLTNHAGEVSFPGGKRDIGDTSNIVVALREA
QEETALNPFDVELIGDLPMQRARNGMRVKPIVGLIPPHVDLKPQPTEIDRIFFASLTELIDAPPTPYKVQYIKQTLYFPS
LQVEDEVVWGLTARMLISLFNYGLGYQKEWPFLLNPPSFYQRKF

Sequences:

>Translated_204_residues
MKGMIKQGLTQQLQQRLRFAKRTQPAEAAVLIAITDEHDPKVLLTRRSTQLTNHAGEVSFPGGKRDIGDTSNIVVALREA
QEETALNPFDVELIGDLPMQRARNGMRVKPIVGLIPPHVDLKPQPTEIDRIFFASLTELIDAPPTPYKVQYIKQTLYFPS
LQVEDEVVWGLTARMLISLFNYGLGYQKEWPFLLNPPSFYQRKF
>Mature_204_residues
MKGMIKQGLTQQLQQRLRFAKRTQPAEAAVLIAITDEHDPKVLLTRRSTQLTNHAGEVSFPGGKRDIGDTSNIVVALREA
QEETALNPFDVELIGDLPMQRARNGMRVKPIVGLIPPHVDLKPQPTEIDRIFFASLTELIDAPPTPYKVQYIKQTLYFPS
LQVEDEVVWGLTARMLISLFNYGLGYQKEWPFLLNPPSFYQRKF

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=166, Percent_Identity=32.5301204819277, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1788115, Length=154, Percent_Identity=38.3116883116883, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17510677, Length=159, Percent_Identity=36.4779874213836, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536993, Length=167, Percent_Identity=35.3293413173653, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI18859683, Length=169, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23202; Mature: 23202

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGMIKQGLTQQLQQRLRFAKRTQPAEAAVLIAITDEHDPKVLLTRRSTQLTNHAGEVSF
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCHHHHCCCCCCCC
PGGKRDIGDTSNIVVALREAQEETALNPFDVELIGDLPMQRARNGMRVKPIVGLIPPHVD
CCCCCCCCCCCCEEEEEEHHHHHHCCCCCCEEEECCCCHHHHCCCCEECCEEECCCCCCC
LKPQPTEIDRIFFASLTELIDAPPTPYKVQYIKQTLYFPSLQVEDEVVWGLTARMLISLF
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
NYGLGYQKEWPFLLNPPSFYQRKF
HHCCCCCCCCCEEECCHHHHHCCC
>Mature Secondary Structure
MKGMIKQGLTQQLQQRLRFAKRTQPAEAAVLIAITDEHDPKVLLTRRSTQLTNHAGEVSF
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCHHHHCCCCCCCC
PGGKRDIGDTSNIVVALREAQEETALNPFDVELIGDLPMQRARNGMRVKPIVGLIPPHVD
CCCCCCCCCCCCEEEEEEHHHHHHCCCCCCEEEECCCCHHHHCCCCEECCEEECCCCCCC
LKPQPTEIDRIFFASLTELIDAPPTPYKVQYIKQTLYFPSLQVEDEVVWGLTARMLISLF
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
NYGLGYQKEWPFLLNPPSFYQRKF
HHCCCCCCCCCEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]