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The map label for this gene is trpB

Identifier: 50083869

GI number: 50083869

Start: 625346

End: 626557

Strand: Direct

Name: trpB

Synonym: ACIAD0636

Alternate gene names: 50083869

Gene position: 625346-626557 (Clockwise)

Preceding gene: 50083868

Following gene: 50083870

Centisome position: 17.38

GC content: 46.29

Gene sequence:

>1212_bases
GTGATTGACTATACGCAATATCCAGATGCTCGTGGGCATTTTGGTATTCATGGCGGACGTTTTGTATCAGAAACACTTAT
GGCGGCACTTGAAGATTTAGAAAATCTTTACAACCGCATGAAAAATGACGAACAGTTTCTGGCAGAATTTGACCGCGATC
TTGCCTATTATGTAGGTCGTCCTAGTCCACTTTATTATGCTGAACGATGGTCAAAGAAGCTCGGTGGTGCGCAAATTTAC
TTAAAACGTGAAGACCTGAATCATACAGGTTCACACAAAGTTAATAACACCATTGGTCAGGCATTATTGGCCAAGCTTTC
TGGCAAAAAACGTATCATTGCAGAAACGGGTGCGGGTCAGCATGGTGTTGCAACTGCAACGATTGCAGCACGTTTGGGCC
TCGAATGTGTCGTGTTCATGGGTGCAGAGGATGTCAAGCGTCAGGCCATGAATGTGTATCGCATGCGTTTGCTTGGTGCG
ACAGTTATTCCTGTACAAAGTGGTTCAAAAACCCTAAAAGATGCCATGAATGAAGCCATGCGCGATTGGGTGACCAATGT
AGACAGTACTTATTATGTGATTGGCACTGTAGCAGGTCCACATCCTTATCCTCAGTTGGTGCGTGATTTCCAGTCGATTA
TTGGACGTGAAGCCCGTCGCCAGATTCAGGAACAGGCAGGACGTTTGCCAGATGCGCTTGTGGCGTGTGTCGGTGGTGGT
TCTAACGCGATCGGGCTGTTTTATCCATTCCTGAATGATCAAGACGTCAAAATGTATGGTGTTGAAGCTGCGGGTCATGG
TATCGAAACAGGCAAGCATTCTGCTCCGCTTAATGCAGGGCATGTGGGTGTATTACATGGTAACCGCACCTATTTGATGA
GTGATCCACAAGGTCAGATTATCGAAACCCACAGTATTTCTGCGGGTCTGGATTACCCTGGTGTTGGCCCTGAGCATAGC
TTTCTCAAAGACATGCATCGTGTTGAATACGTACCTATTGACGATAACGAAGCATTACAAGGCTTCCGTGACCTTACTCG
CATTGAAGGCATTATTCCTGCAATCGAGAGTGCTCATGCAATGGCTTATGTCACCAAGCTGGCACCTACCATGGACAAAG
ATCAGATTATCATTGCCAATGTGTCAGGTCGTGGCGATAAAGACCTAATGACGGTGGCACGTATTGATGGCATCGAGATG
GTAGAAATGTAA

Upstream 100 bases:

>100_bases
GTGGATGTGAGCGGAGGGGTAGAGGCCGCAAAAGGTATTAAAGATAAACAACTCATCGAACGATTTATGCAAGGAGTCCA
ATGTGGATCAGCAAAATAAC

Downstream 100 bases:

>100_bases
TTCTAATCATGAACGTGATGTGGAAATGGGCAACATCAATGTGGCCCATTTTTTTGGAGAAAGATAAGCATGTTGAGTTT
ATTTATGGTGATGCTGGGTG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MIDYTQYPDARGHFGIHGGRFVSETLMAALEDLENLYNRMKNDEQFLAEFDRDLAYYVGRPSPLYYAERWSKKLGGAQIY
LKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQHGVATATIAARLGLECVVFMGAEDVKRQAMNVYRMRLLGA
TVIPVQSGSKTLKDAMNEAMRDWVTNVDSTYYVIGTVAGPHPYPQLVRDFQSIIGREARRQIQEQAGRLPDALVACVGGG
SNAIGLFYPFLNDQDVKMYGVEAAGHGIETGKHSAPLNAGHVGVLHGNRTYLMSDPQGQIIETHSISAGLDYPGVGPEHS
FLKDMHRVEYVPIDDNEALQGFRDLTRIEGIIPAIESAHAMAYVTKLAPTMDKDQIIIANVSGRGDKDLMTVARIDGIEM
VEM

Sequences:

>Translated_403_residues
MIDYTQYPDARGHFGIHGGRFVSETLMAALEDLENLYNRMKNDEQFLAEFDRDLAYYVGRPSPLYYAERWSKKLGGAQIY
LKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQHGVATATIAARLGLECVVFMGAEDVKRQAMNVYRMRLLGA
TVIPVQSGSKTLKDAMNEAMRDWVTNVDSTYYVIGTVAGPHPYPQLVRDFQSIIGREARRQIQEQAGRLPDALVACVGGG
SNAIGLFYPFLNDQDVKMYGVEAAGHGIETGKHSAPLNAGHVGVLHGNRTYLMSDPQGQIIETHSISAGLDYPGVGPEHS
FLKDMHRVEYVPIDDNEALQGFRDLTRIEGIIPAIESAHAMAYVTKLAPTMDKDQIIIANVSGRGDKDLMTVARIDGIEM
VEM
>Mature_403_residues
MIDYTQYPDARGHFGIHGGRFVSETLMAALEDLENLYNRMKNDEQFLAEFDRDLAYYVGRPSPLYYAERWSKKLGGAQIY
LKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQHGVATATIAARLGLECVVFMGAEDVKRQAMNVYRMRLLGA
TVIPVQSGSKTLKDAMNEAMRDWVTNVDSTYYVIGTVAGPHPYPQLVRDFQSIIGREARRQIQEQAGRLPDALVACVGGG
SNAIGLFYPFLNDQDVKMYGVEAAGHGIETGKHSAPLNAGHVGVLHGNRTYLMSDPQGQIIETHSISAGLDYPGVGPEHS
FLKDMHRVEYVPIDDNEALQGFRDLTRIEGIIPAIESAHAMAYVTKLAPTMDKDQIIIANVSGRGDKDLMTVARIDGIEM
VEM

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=53.90625, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321412, Length=383, Percent_Identity=56.9190600522193, Blast_Score=456, Evalue=1e-129,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_ACIAD (Q6FEF1)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045379.1
- HSSP:   P0A2K1
- ProteinModelPortal:   Q6FEF1
- SMR:   Q6FEF1
- STRING:   Q6FEF1
- GeneID:   2880734
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0636
- NMPDR:   fig|62977.3.peg.282
- eggNOG:   COG0133
- HOGENOM:   HBG303148
- OMA:   LKREDLC
- PhylomeDB:   Q6FEF1
- ProtClustDB:   PRK04346
- BioCyc:   ASP62977:ACIAD0636-MONOMER
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 44323; Mature: 44323

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDYTQYPDARGHFGIHGGRFVSETLMAALEDLENLYNRMKNDEQFLAEFDRDLAYYVGR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
PSPLYYAERWSKKLGGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQ
CCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
HGVATATIAARLGLECVVFMGAEDVKRQAMNVYRMRLLGATVIPVQSGSKTLKDAMNEAM
CCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHH
RDWVTNVDSTYYVIGTVAGPHPYPQLVRDFQSIIGREARRQIQEQAGRLPDALVACVGGG
HHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCC
SNAIGLFYPFLNDQDVKMYGVEAAGHGIETGKHSAPLNAGHVGVLHGNRTYLMSDPQGQI
CCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCE
IETHSISAGLDYPGVGPEHSFLKDMHRVEYVPIDDNEALQGFRDLTRIEGIIPAIESAHA
EEECCCCCCCCCCCCCCCHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
MAYVTKLAPTMDKDQIIIANVSGRGDKDLMTVARIDGIEMVEM
HHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MIDYTQYPDARGHFGIHGGRFVSETLMAALEDLENLYNRMKNDEQFLAEFDRDLAYYVGR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
PSPLYYAERWSKKLGGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQ
CCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCC
HGVATATIAARLGLECVVFMGAEDVKRQAMNVYRMRLLGATVIPVQSGSKTLKDAMNEAM
CCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHH
RDWVTNVDSTYYVIGTVAGPHPYPQLVRDFQSIIGREARRQIQEQAGRLPDALVACVGGG
HHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCC
SNAIGLFYPFLNDQDVKMYGVEAAGHGIETGKHSAPLNAGHVGVLHGNRTYLMSDPQGQI
CCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCEEEEEECCCCCE
IETHSISAGLDYPGVGPEHSFLKDMHRVEYVPIDDNEALQGFRDLTRIEGIIPAIESAHA
EEECCCCCCCCCCCCCCCHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
MAYVTKLAPTMDKDQIIIANVSGRGDKDLMTVARIDGIEMVEM
HHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA