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The map label for this gene is gph [C]

Identifier: 50083693

GI number: 50083693

Start: 441089

End: 441754

Strand: Direct

Name: gph [C]

Synonym: ACIAD0443

Alternate gene names: 50083693

Gene position: 441089-441754 (Clockwise)

Preceding gene: 50083692

Following gene: 50083694

Centisome position: 12.26

GC content: 43.09

Gene sequence:

>666_bases
ATGAAGCGTCCAGAACTGATTATTTTTGACTGGGATGGCACCTTATTTGATTCCGTGGGACAAATTGTTGCGAGTTTGAG
ATTCGCAGCAGATCAATTCAATCAACCACTCACCGATGAAGCTGCACAAAGTATTATTGGTCTGGGTTTGCCAGAGGTCA
TGCAAGCCCTATTTCCACAGGTTCCTCATCTGCATCAGGAGATTTTGGTACATTATGGTGAGCATTATGTAGAGAATTCT
AAGCATGATGCGTGGTTTGAGGGTGTAGCCGAGTTATTACATGATCTTAAAGCACAAGGCATAAAACTCGCTGTAGCAAC
AGGCAAAAGCCGTCGTGGGTTAGATCGAGTGCTCAATAAAACACAAAGTCATGAGCTGTTTGATATTACGCGTGCAGCCA
GCGAAACCATGTCTAAGCCTCATCCACGCATGCTAGAGGAAATTTTGCAGGTCACACAAGTTGAAGCTCAACATGCCATT
ATGGTCGGTGATAGTAGTTATGATCTTGAAATGGCCAAGAATATTGATATGCCACGTGTTGGGGTCAGCTATGGTGTACA
TGAGGTTGACGTGCTGCAACGCTATGAGCCTTTGACAATTGTAGATAGTATTGCAGAATTGCATCATTATTTAACACAGT
TGCTTCAAGAAAAAATCCACGCTTAG

Upstream 100 bases:

>100_bases
GCTTACATGCGATGCGTCTTGAAATTCCAGGCTATCCTGTGATTGAAGCACCGCTTGCAGAGGATATTCAAAGCGTTGTA
GCGCAGTTGAGAGCACGTAA

Downstream 100 bases:

>100_bases
ATCTTAATTAGGCATCTAGTAAAACAGACAGAGAGTAAACCTCAGCGTGTTTCTCTCTGATAAAAAACTAGAGGTTCAGA
TGAGTCGTTCAATTCGATTA

Product: phosphoglycolate phosphatase protein

Products: glycolate; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKRPELIIFDWDGTLFDSVGQIVASLRFAADQFNQPLTDEAAQSIIGLGLPEVMQALFPQVPHLHQEILVHYGEHYVENS
KHDAWFEGVAELLHDLKAQGIKLAVATGKSRRGLDRVLNKTQSHELFDITRAASETMSKPHPRMLEEILQVTQVEAQHAI
MVGDSSYDLEMAKNIDMPRVGVSYGVHEVDVLQRYEPLTIVDSIAELHHYLTQLLQEKIHA

Sequences:

>Translated_221_residues
MKRPELIIFDWDGTLFDSVGQIVASLRFAADQFNQPLTDEAAQSIIGLGLPEVMQALFPQVPHLHQEILVHYGEHYVENS
KHDAWFEGVAELLHDLKAQGIKLAVATGKSRRGLDRVLNKTQSHELFDITRAASETMSKPHPRMLEEILQVTQVEAQHAI
MVGDSSYDLEMAKNIDMPRVGVSYGVHEVDVLQRYEPLTIVDSIAELHHYLTQLLQEKIHA
>Mature_221_residues
MKRPELIIFDWDGTLFDSVGQIVASLRFAADQFNQPLTDEAAQSIIGLGLPEVMQALFPQVPHLHQEILVHYGEHYVENS
KHDAWFEGVAELLHDLKAQGIKLAVATGKSRRGLDRVLNKTQSHELFDITRAASETMSKPHPRMLEEILQVTQVEAQHAI
MVGDSSYDLEMAKNIDMPRVGVSYGVHEVDVLQRYEPLTIVDSIAELHHYLTQLLQEKIHA

Specific function: Unknown

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.18

Molecular weight: Translated: 24965; Mature: 24965

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPELIIFDWDGTLFDSVGQIVASLRFAADQFNQPLTDEAAQSIIGLGLPEVMQALFPQ
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCC
VPHLHQEILVHYGEHYVENSKHDAWFEGVAELLHDLKAQGIKLAVATGKSRRGLDRVLNK
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHH
TQSHELFDITRAASETMSKPHPRMLEEILQVTQVEAQHAIMVGDSSYDLEMAKNIDMPRV
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCCCCCC
GVSYGVHEVDVLQRYEPLTIVDSIAELHHYLTQLLQEKIHA
HHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRPELIIFDWDGTLFDSVGQIVASLRFAADQFNQPLTDEAAQSIIGLGLPEVMQALFPQ
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCC
VPHLHQEILVHYGEHYVENSKHDAWFEGVAELLHDLKAQGIKLAVATGKSRRGLDRVLNK
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHH
TQSHELFDITRAASETMSKPHPRMLEEILQVTQVEAQHAIMVGDSSYDLEMAKNIDMPRV
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCCCCCC
GVSYGVHEVDVLQRYEPLTIVDSIAELHHYLTQLLQEKIHA
HHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.57 {phosphoglycolate}} [C]

Substrates: 2-phosphoglycolate; H2O

Specific reaction: 2-phosphoglycolate + H2O = glycolate + phosphate

General reaction: Additional information:

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]