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The map label for this gene is yggW [H]

Identifier: 50083685

GI number: 50083685

Start: 429708

End: 430865

Strand: Direct

Name: yggW [H]

Synonym: ACIAD0432

Alternate gene names: 50083685

Gene position: 429708-430865 (Clockwise)

Preceding gene: 50083682

Following gene: 50083687

Centisome position: 11.94

GC content: 41.54

Gene sequence:

>1158_bases
TTGACTGTTTTACTTAACCCTGCCGAAATTCCACTGTCATTATATATCCATATGCCGTGGTGTGTACGTAAGTGTCCTTA
CTGTGATTTTAATTCACATGCTGTGCCTAATGGCGCTTTATCACTGGAGCTAGAGCAACAATATTTACAGGCATTGGTGG
CTGATTTTGAAACGCAGGTGAAATTTGTTCAGGGACGCAAGATTCATAGTGTCTTTATTGGCGGAGGTACGCCATCGCTG
ATTTCTGCCCAAGGTTATCAATGGCTGTTTGAAAAAATACGTGCTTTAGTCGATTTCGAACAGGACTGTGAAATTACATT
AGAAGCTAATCCAGGAACGGTCGAACATGATCCTTTTGCCGATTATTTAGAAGCGGGAATTAATCGGTTATCGCTTGGGG
TACAAAGTTTTGATCAGGATCATTTAGAGCGTCTCGGGCGTATTCATAGTTCAGAGAATGCAATTGAAGCGATCAAATTG
GCAAAACAGGCGGGTTTTGAGCGTGTGAATGCCGATTTAATGCATGGATTGTCACAACAAACTTTAGAGCAAGCGTTACT
CGACTTAAAACTTGCGGTAGACAATGGCGCAACACATATCAGTTGGTATCAATTGACCATTGAGCCCAATACCGTTTTTT
TTAGAACTCAGCCTGTCTTACCACAAGATGAAATTCTTGAACAGATTCAACGACAAGGTGAGCAGTATTTAAAAGCACAG
GGTTTTAGCAATTATGAAGTTTCTGCATGGCGCAAAGAAAAACCTTCAGCACATAATTTGAATTATTGGCAATTTGGCGA
TTATCTGGCGATTGGCGCAGGGGCACATGGCAAAGTCACACAACCTGATGGTGTTTATCGGTTTCAGAAAACGCGTTTGC
CTAAGGATTATCTCGCTAAAGTTCCAGCCGAGCATGTACAGTGGAAACGTATTGAAGCAGATGAATTACCATTTGAATTT
ATGATGAATGCACTGCGTTTAAATGAGGGTGTAGCGACAAACTTGTATGAGCAGCGTACAGGATTATCACTGGTCGATAT
TGAGCCTGCCCTAAATGCTTTGCGTCAGAAAAAATTATTGGTGAATGATCCCGAGCGAATTGCCTGCACCGAGCAAGGGC
ATCTGTTTTTAAATTCAGTCTTGGAAGAATTTCTATAA

Upstream 100 bases:

>100_bases
TTTTGGTTATTTTTAGTCTAAAGCAATTCGAACGGCTTGAGCGTATGTGATTGCTATAGTCATGTTAAACTAATGCAGTT
TCATTGTCTGAGCACACTTT

Downstream 100 bases:

>100_bases
TTTTTCTCTAACACCGTCATTTTTAAAATCGGTCCATGTGATTGAACATATCTCAGTAAAATCACGATGTAGTCTTCAAT
AAAAATGGCTAGGGAATAGG

Product: oxidase; coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTVLLNPAEIPLSLYIHMPWCVRKCPYCDFNSHAVPNGALSLELEQQYLQALVADFETQVKFVQGRKIHSVFIGGGTPSL
ISAQGYQWLFEKIRALVDFEQDCEITLEANPGTVEHDPFADYLEAGINRLSLGVQSFDQDHLERLGRIHSSENAIEAIKL
AKQAGFERVNADLMHGLSQQTLEQALLDLKLAVDNGATHISWYQLTIEPNTVFFRTQPVLPQDEILEQIQRQGEQYLKAQ
GFSNYEVSAWRKEKPSAHNLNYWQFGDYLAIGAGAHGKVTQPDGVYRFQKTRLPKDYLAKVPAEHVQWKRIEADELPFEF
MMNALRLNEGVATNLYEQRTGLSLVDIEPALNALRQKKLLVNDPERIACTEQGHLFLNSVLEEFL

Sequences:

>Translated_385_residues
MTVLLNPAEIPLSLYIHMPWCVRKCPYCDFNSHAVPNGALSLELEQQYLQALVADFETQVKFVQGRKIHSVFIGGGTPSL
ISAQGYQWLFEKIRALVDFEQDCEITLEANPGTVEHDPFADYLEAGINRLSLGVQSFDQDHLERLGRIHSSENAIEAIKL
AKQAGFERVNADLMHGLSQQTLEQALLDLKLAVDNGATHISWYQLTIEPNTVFFRTQPVLPQDEILEQIQRQGEQYLKAQ
GFSNYEVSAWRKEKPSAHNLNYWQFGDYLAIGAGAHGKVTQPDGVYRFQKTRLPKDYLAKVPAEHVQWKRIEADELPFEF
MMNALRLNEGVATNLYEQRTGLSLVDIEPALNALRQKKLLVNDPERIACTEQGHLFLNSVLEEFL
>Mature_384_residues
TVLLNPAEIPLSLYIHMPWCVRKCPYCDFNSHAVPNGALSLELEQQYLQALVADFETQVKFVQGRKIHSVFIGGGTPSLI
SAQGYQWLFEKIRALVDFEQDCEITLEANPGTVEHDPFADYLEAGINRLSLGVQSFDQDHLERLGRIHSSENAIEAIKLA
KQAGFERVNADLMHGLSQQTLEQALLDLKLAVDNGATHISWYQLTIEPNTVFFRTQPVLPQDEILEQIQRQGEQYLKAQG
FSNYEVSAWRKEKPSAHNLNYWQFGDYLAIGAGAHGKVTQPDGVYRFQKTRLPKDYLAKVPAEHVQWKRIEADELPFEFM
MNALRLNEGVATNLYEQRTGLSLVDIEPALNALRQKKLLVNDPERIACTEQGHLFLNSVLEEFL

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=278, Percent_Identity=36.6906474820144, Blast_Score=176, Evalue=3e-44,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=49.7354497354497, Blast_Score=354, Evalue=5e-99,
Organism=Escherichia coli, GI87082341, Length=206, Percent_Identity=31.5533980582524, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 43724; Mature: 43593

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLLNPAEIPLSLYIHMPWCVRKCPYCDFNSHAVPNGALSLELEQQYLQALVADFETQV
CEEEECCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
KFVQGRKIHSVFIGGGTPSLISAQGYQWLFEKIRALVDFEQDCEITLEANPGTVEHDPFA
HHHCCCEEEEEEECCCCCCHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHH
DYLEAGINRLSLGVQSFDQDHLERLGRIHSSENAIEAIKLAKQAGFERVNADLMHGLSQQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHCHHHHHCCHHH
TLEQALLDLKLAVDNGATHISWYQLTIEPNTVFFRTQPVLPQDEILEQIQRQGEQYLKAQ
HHHHHHHHEEEEECCCCCEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
GFSNYEVSAWRKEKPSAHNLNYWQFGDYLAIGAGAHGKVTQPDGVYRFQKTRLPKDYLAK
CCCCCCEEHHHCCCCCCCCCCCEECCCEEEECCCCCCCCCCCCCCCHHHHHCCCHHHHHH
VPAEHVQWKRIEADELPFEFMMNALRLNEGVATNLYEQRTGLSLVDIEPALNALRQKKLL
CCHHHHHHHCCCHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEECHHHHHHHHHCCCC
VNDPERIACTEQGHLFLNSVLEEFL
CCCCCCEEECCCCHHHHHHHHHHHC
>Mature Secondary Structure 
TVLLNPAEIPLSLYIHMPWCVRKCPYCDFNSHAVPNGALSLELEQQYLQALVADFETQV
EEEECCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
KFVQGRKIHSVFIGGGTPSLISAQGYQWLFEKIRALVDFEQDCEITLEANPGTVEHDPFA
HHHCCCEEEEEEECCCCCCHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHH
DYLEAGINRLSLGVQSFDQDHLERLGRIHSSENAIEAIKLAKQAGFERVNADLMHGLSQQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHCHHHHHCCHHH
TLEQALLDLKLAVDNGATHISWYQLTIEPNTVFFRTQPVLPQDEILEQIQRQGEQYLKAQ
HHHHHHHHEEEEECCCCCEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
GFSNYEVSAWRKEKPSAHNLNYWQFGDYLAIGAGAHGKVTQPDGVYRFQKTRLPKDYLAK
CCCCCCEEHHHCCCCCCCCCCCEECCCEEEECCCCCCCCCCCCCCCHHHHHCCCHHHHHH
VPAEHVQWKRIEADELPFEFMMNALRLNEGVATNLYEQRTGLSLVDIEPALNALRQKKLL
CCHHHHHHHCCCHHCCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEECHHHHHHHHHCCCC
VNDPERIACTEQGHLFLNSVLEEFL
CCCCCCEEECCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]