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The map label for this gene is recD [H]

Identifier: 50083655

GI number: 50083655

Start: 397904

End: 399682

Strand: Direct

Name: recD [H]

Synonym: ACIAD0399

Alternate gene names: 50083655

Gene position: 397904-399682 (Clockwise)

Preceding gene: 50083654

Following gene: 50083657

Centisome position: 11.06

GC content: 43.79

Gene sequence:

>1779_bases
GTGGATAAGCAAAACATCAGTAAAGACACTGATTTAGCATGGCTTGAGACGTGGAGCAAGTATCTTGTCCAGACGCCGTT
CAATCTCGGGGAGCGCAATTCTGCCCAAATTACGGCAATGTTGCAAGCATTAATTGAAGCAAGTGTGCAAGGCGATAGCG
GTTTGGTGGTTTCTTCATCAATTGTGGCTGAATTGGGAAATTACGTTCTGGATGAAGCTCAGGCCCAAACTCAGGTTGCA
CCCATGATTTACGATGGGGAACTGCTGGCACTGTATCGTTACTGGATGCTTGAACAGCGTTTAGCGATACAGGTGGTGCG
TTTGAGTCAGCAAGTTATTCCGCCTGTCGAGGTTATGCCTCATCTCGATTTACTGACCGATCCGCATCAGCAAGCAGCAA
TGTCGATGGTTGCTACCCAAGCATTTAGTCTGATTACGGGCGGTCCAGGAACAGGAAAAACCTATACACTTGCCCGAATT
ATTGCTGTTTTGAATCAAGCAATTCCGAATATTCGTATTGCTATGGCAGCACCTACGGGTAAAGCCGCTCAGCGGATGCA
GGAAGCATTACAGGCTTCATTTAATGATGAAAAGCTGACAGCTTCGGGTTTATTGAGTCATGAATTAAAACAGCAAACCA
CGCAAACACTGCATCGTTTACTCGGACTTGGACATCAGCAGTTACCGCGTTTTCATGCCAAACAACCTTTACCGTATGAT
GTGATTGTGGTGGATGAGGCATCTATGCTTGATTTGAAACTGGCCACCTTATTGTTCGAAGCTGTGCCAGCAGGTTGTCG
ACTCATTTTACTGGGGGATGCCAATCAGTTGGCTTCGGTTGATGTGGGTTCGGTACTGGCAGATTTGCAGCAAGTCGAGG
CACTTGAACAGAATCGAGTCAATCTGGTGACCAGCCGTCGTTTTCGCGAAGGCGCAAAAATTGGTGAATTTGCCCAGTTT
ATTCAATGTCTTGATGTAACGTGGGATCCACAGCAAATTCTGCATGAGTTTGAGCATCAAATAGCTGTACCTCAAGCATT
ACAGCCAGTTTCACTATTGCACGATAGGGATGATATGGTGCAGCTTGAATATCTTCCACCTAAGGTAAACTTAGAGCACC
TTACACCGTATTATCAGAAACTCATGCAAGGCTTTGAAACATTTGCCCAGCAGCTCAAGCATTACCGATTACATGATTAT
GCAGAATCGGAAGTGGCTGCAGTGATTCAGGCATTTGATGATTATCGTATTTTGGTTGCCATTCGCTTTGGAGATTTTGG
TCTTGAACACATCAACAAAATGGTTGAACAGTGGCTCACTCAATATTTGGGCATTTTGCCTGTAGGTGGCTGGTATATCG
GTCGTCCCGTCATGATGACCTATAACGATTATCAGCTTGGACTTTCCAATGGAGATATTGGGATCTGTTTTAGACATCGA
ACACAATATGATCAGTTTGAGGTGTATTTCCCAAGTCTGGATAAATGGATTGCTGCCAATCGTCTCCCTAAAAATATTCA
GACTGCATTTGCACTCACCATTCATAAATCACAAGGATCAGAATTTCGGCATACAGCGATTGTATTTGATCATATGGCAC
AAAAAGTGCTGAGTCAGGAACTCATTTATACCGCGATTACGCGTGCTAAACAGGCGGTTAGTCTATTGGTCGATCAAGAT
GCCTTGCTACAGTCTCTTATTATTCGAACGACACGAAAAAGTGGCTTAATTAAAAAAATTAATAAAGATATCATTTTAGT
AAGTTTACCTAAGGAGTAG

Upstream 100 bases:

>100_bases
GATGAAAATGGGGGTGTTTTCAATAATACTATATAAATCAAAAACTTAATTTGTGGATAAATGTGTTTATAACTATGTGG
ACAAGCTTGAGGATAACTGT

Downstream 100 bases:

>100_bases
ACAACTCTGTACGAAATTGCTTACACAGATTCGAGAAATTTGCTTATAGAGTCGAATGTCAGATTCTGAGAAGATGATCG
TGCAAAAATACTCAGCATGG

Product: exonuclease V, alpha subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MDKQNISKDTDLAWLETWSKYLVQTPFNLGERNSAQITAMLQALIEASVQGDSGLVVSSSIVAELGNYVLDEAQAQTQVA
PMIYDGELLALYRYWMLEQRLAIQVVRLSQQVIPPVEVMPHLDLLTDPHQQAAMSMVATQAFSLITGGPGTGKTYTLARI
IAVLNQAIPNIRIAMAAPTGKAAQRMQEALQASFNDEKLTASGLLSHELKQQTTQTLHRLLGLGHQQLPRFHAKQPLPYD
VIVVDEASMLDLKLATLLFEAVPAGCRLILLGDANQLASVDVGSVLADLQQVEALEQNRVNLVTSRRFREGAKIGEFAQF
IQCLDVTWDPQQILHEFEHQIAVPQALQPVSLLHDRDDMVQLEYLPPKVNLEHLTPYYQKLMQGFETFAQQLKHYRLHDY
AESEVAAVIQAFDDYRILVAIRFGDFGLEHINKMVEQWLTQYLGILPVGGWYIGRPVMMTYNDYQLGLSNGDIGICFRHR
TQYDQFEVYFPSLDKWIAANRLPKNIQTAFALTIHKSQGSEFRHTAIVFDHMAQKVLSQELIYTAITRAKQAVSLLVDQD
ALLQSLIIRTTRKSGLIKKINKDIILVSLPKE

Sequences:

>Translated_592_residues
MDKQNISKDTDLAWLETWSKYLVQTPFNLGERNSAQITAMLQALIEASVQGDSGLVVSSSIVAELGNYVLDEAQAQTQVA
PMIYDGELLALYRYWMLEQRLAIQVVRLSQQVIPPVEVMPHLDLLTDPHQQAAMSMVATQAFSLITGGPGTGKTYTLARI
IAVLNQAIPNIRIAMAAPTGKAAQRMQEALQASFNDEKLTASGLLSHELKQQTTQTLHRLLGLGHQQLPRFHAKQPLPYD
VIVVDEASMLDLKLATLLFEAVPAGCRLILLGDANQLASVDVGSVLADLQQVEALEQNRVNLVTSRRFREGAKIGEFAQF
IQCLDVTWDPQQILHEFEHQIAVPQALQPVSLLHDRDDMVQLEYLPPKVNLEHLTPYYQKLMQGFETFAQQLKHYRLHDY
AESEVAAVIQAFDDYRILVAIRFGDFGLEHINKMVEQWLTQYLGILPVGGWYIGRPVMMTYNDYQLGLSNGDIGICFRHR
TQYDQFEVYFPSLDKWIAANRLPKNIQTAFALTIHKSQGSEFRHTAIVFDHMAQKVLSQELIYTAITRAKQAVSLLVDQD
ALLQSLIIRTTRKSGLIKKINKDIILVSLPKE
>Mature_592_residues
MDKQNISKDTDLAWLETWSKYLVQTPFNLGERNSAQITAMLQALIEASVQGDSGLVVSSSIVAELGNYVLDEAQAQTQVA
PMIYDGELLALYRYWMLEQRLAIQVVRLSQQVIPPVEVMPHLDLLTDPHQQAAMSMVATQAFSLITGGPGTGKTYTLARI
IAVLNQAIPNIRIAMAAPTGKAAQRMQEALQASFNDEKLTASGLLSHELKQQTTQTLHRLLGLGHQQLPRFHAKQPLPYD
VIVVDEASMLDLKLATLLFEAVPAGCRLILLGDANQLASVDVGSVLADLQQVEALEQNRVNLVTSRRFREGAKIGEFAQF
IQCLDVTWDPQQILHEFEHQIAVPQALQPVSLLHDRDDMVQLEYLPPKVNLEHLTPYYQKLMQGFETFAQQLKHYRLHDY
AESEVAAVIQAFDDYRILVAIRFGDFGLEHINKMVEQWLTQYLGILPVGGWYIGRPVMMTYNDYQLGLSNGDIGICFRHR
TQYDQFEVYFPSLDKWIAANRLPKNIQTAFALTIHKSQGSEFRHTAIVFDHMAQKVLSQELIYTAITRAKQAVSLLVDQD
ALLQSLIIRTTRKSGLIKKINKDIILVSLPKE

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=576, Percent_Identity=34.5486111111111, Blast_Score=223, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 66624; Mature: 66624

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKQNISKDTDLAWLETWSKYLVQTPFNLGERNSAQITAMLQALIEASVQGDSGLVVSSS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHH
IVAELGNYVLDEAQAQTQVAPMIYDGELLALYRYWMLEQRLAIQVVRLSQQVIPPVEVMP
HHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
HLDLLTDPHQQAAMSMVATQAFSLITGGPGTGKTYTLARIIAVLNQAIPNIRIAMAAPTG
CCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC
KAAQRMQEALQASFNDEKLTASGLLSHELKQQTTQTLHRLLGLGHQQLPRFHAKQPLPYD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCEE
VIVVDEASMLDLKLATLLFEAVPAGCRLILLGDANQLASVDVGSVLADLQQVEALEQNRV
EEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCHHHHHHHHHHHHHHHHHCCH
NLVTSRRFREGAKIGEFAQFIQCLDVTWDPQQILHEFEHQIAVPQALQPVSLLHDRDDMV
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCHHHHHCCCCCEE
QLEYLPPKVNLEHLTPYYQKLMQGFETFAQQLKHYRLHDYAESEVAAVIQAFDDYRILVA
EEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
IRFGDFGLEHINKMVEQWLTQYLGILPVGGWYIGRPVMMTYNDYQLGLSNGDIGICFRHR
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCEEEECCCCCEEEEEECC
TQYDQFEVYFPSLDKWIAANRLPKNIQTAFALTIHKSQGSEFRHTAIVFDHMAQKVLSQE
CCCCCEEEECCCHHHHHHHCCCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LIYTAITRAKQAVSLLVDQDALLQSLIIRTTRKSGLIKKINKDIILVSLPKE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MDKQNISKDTDLAWLETWSKYLVQTPFNLGERNSAQITAMLQALIEASVQGDSGLVVSSS
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHH
IVAELGNYVLDEAQAQTQVAPMIYDGELLALYRYWMLEQRLAIQVVRLSQQVIPPVEVMP
HHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
HLDLLTDPHQQAAMSMVATQAFSLITGGPGTGKTYTLARIIAVLNQAIPNIRIAMAAPTG
CCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC
KAAQRMQEALQASFNDEKLTASGLLSHELKQQTTQTLHRLLGLGHQQLPRFHAKQPLPYD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCEE
VIVVDEASMLDLKLATLLFEAVPAGCRLILLGDANQLASVDVGSVLADLQQVEALEQNRV
EEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHCHHHHHHHHHHHHHHHHHCCH
NLVTSRRFREGAKIGEFAQFIQCLDVTWDPQQILHEFEHQIAVPQALQPVSLLHDRDDMV
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCHHHHHCCCCCEE
QLEYLPPKVNLEHLTPYYQKLMQGFETFAQQLKHYRLHDYAESEVAAVIQAFDDYRILVA
EEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
IRFGDFGLEHINKMVEQWLTQYLGILPVGGWYIGRPVMMTYNDYQLGLSNGDIGICFRHR
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCEEEECCCCCEEEEEECC
TQYDQFEVYFPSLDKWIAANRLPKNIQTAFALTIHKSQGSEFRHTAIVFDHMAQKVLSQE
CCCCCEEEECCCHHHHHHHCCCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LIYTAITRAKQAVSLLVDQDALLQSLIIRTTRKSGLIKKINKDIILVSLPKE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]