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The map label for this gene is qseD [H]

Identifier: 50083593

GI number: 50083593

Start: 322807

End: 323703

Strand: Reverse

Name: qseD [H]

Synonym: ACIAD0323

Alternate gene names: 50083593

Gene position: 323703-322807 (Counterclockwise)

Preceding gene: 50083594

Following gene: 50083588

Centisome position: 9.0

GC content: 32.78

Gene sequence:

>897_bases
ATGTCCTTGATACAAAATATTGAATTAAAGTGGTTGTACGATCTGATTACTTTAGAAAAGTATCGGAACTTCACCATGGC
CGCTGATATGCGAAATATTTCTCAATCATCACTCAGTAGACGCATTCAAACCCTAGAAAATACGTTAGGATTTGAGGTCT
TTAATCGAGAAATGTCACCATTACAACTCACCGAGAAAGGCAAGCTCTTTGTTTTACATGCAAGGAGCTTTCTCGATGAT
TTTGAATATAATATTGATAAAATTAAAGGAACTGACAATATCAGAAGTAAAGTGACCATTGCTTCTGCCCATTCTTTAGC
TGGCTATATTTTTCCAAAAATCTTAGGCAATCTTAAAAATTATCAAGAAAAAATCTTTCATGTCGAAGCAATCAATGTCA
ATGAAACGGTAGACCATTTACGAAATGGAAAATGTGATTTTATTGCTTCATTTTATGATGATGAATTGATGAATCCACAG
TTTTTATGCCATAAAATTTTTTCTGCAAAACTGTATTTAGTGACCGCACCGAATCATCTTGGGCGTCCAAAATTCTCTTT
AGAAGATCGGTCATTGCCATTAATGAATTATACCGATGATAGCTATATGGGCAAAAAGGTCAATAAATTTCTTCAAGACA
GTCAATCTGAATATTTTAATATTACTTTTGTTTCTTCTATGAGTATTTTGCTTAAAGATATGATTAAAGGGGGTTTTGGT
ATTGGATGGTTACCCGATTATAGTATTCAGGAAGAACTTAAAAATAATGAATTGATGATTATTCCGTTAAAAGATTCTGT
TTTATCCGTTGATATCTACTTATATAGAAGTAGCTCAAGATTGAATGCAGCATCAGAAGGTCTATGGAACTTCATTAAAG
CAATTGACTGGACATGA

Upstream 100 bases:

>100_bases
ACTAGACAGGTAATTATGTTAAAATCAAACTTATATAACCAGTTATTTTTAGTGTGTAACAGTAGTTATTGCTCTTGATT
AGGCAATTCAAAAATGGTGA

Downstream 100 bases:

>100_bases
TCCTAGACAGTATCGTGGACAACAAATCCCTCTAAATTCTTGAAATATTTCTGTTCAAAGGCTTCTGGGCTTAACCAGCC
GTTTGTAGAATGTCGTCTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSLIQNIELKWLYDLITLEKYRNFTMAADMRNISQSSLSRRIQTLENTLGFEVFNREMSPLQLTEKGKLFVLHARSFLDD
FEYNIDKIKGTDNIRSKVTIASAHSLAGYIFPKILGNLKNYQEKIFHVEAINVNETVDHLRNGKCDFIASFYDDELMNPQ
FLCHKIFSAKLYLVTAPNHLGRPKFSLEDRSLPLMNYTDDSYMGKKVNKFLQDSQSEYFNITFVSSMSILLKDMIKGGFG
IGWLPDYSIQEELKNNELMIIPLKDSVLSVDIYLYRSSSRLNAASEGLWNFIKAIDWT

Sequences:

>Translated_298_residues
MSLIQNIELKWLYDLITLEKYRNFTMAADMRNISQSSLSRRIQTLENTLGFEVFNREMSPLQLTEKGKLFVLHARSFLDD
FEYNIDKIKGTDNIRSKVTIASAHSLAGYIFPKILGNLKNYQEKIFHVEAINVNETVDHLRNGKCDFIASFYDDELMNPQ
FLCHKIFSAKLYLVTAPNHLGRPKFSLEDRSLPLMNYTDDSYMGKKVNKFLQDSQSEYFNITFVSSMSILLKDMIKGGFG
IGWLPDYSIQEELKNNELMIIPLKDSVLSVDIYLYRSSSRLNAASEGLWNFIKAIDWT
>Mature_297_residues
SLIQNIELKWLYDLITLEKYRNFTMAADMRNISQSSLSRRIQTLENTLGFEVFNREMSPLQLTEKGKLFVLHARSFLDDF
EYNIDKIKGTDNIRSKVTIASAHSLAGYIFPKILGNLKNYQEKIFHVEAINVNETVDHLRNGKCDFIASFYDDELMNPQF
LCHKIFSAKLYLVTAPNHLGRPKFSLEDRSLPLMNYTDDSYMGKKVNKFLQDSQSEYFNITFVSSMSILLKDMIKGGFGI
GWLPDYSIQEELKNNELMIIPLKDSVLSVDIYLYRSSSRLNAASEGLWNFIKAIDWT

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=296, Percent_Identity=39.8648648648649, Blast_Score=241, Evalue=5e-65,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34500; Mature: 34369

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIQNIELKWLYDLITLEKYRNFTMAADMRNISQSSLSRRIQTLENTLGFEVFNREMSP
CCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LQLTEKGKLFVLHARSFLDDFEYNIDKIKGTDNIRSKVTIASAHSLAGYIFPKILGNLKN
EEEECCCCEEEEECHHHHHHHHCCHHEECCCCCHHHEEEEEHHHHHHHHHHHHHHHHHHH
YQEKIFHVEAINVNETVDHLRNGKCDFIASFYDDELMNPQFLCHKIFSAKLYLVTAPNHL
HHHHHEEEEEECCHHHHHHHHCCCEEEEEEHHCCCCCCHHHHHHHHHCCEEEEEECCCCC
GRPKFSLEDRSLPLMNYTDDSYMGKKVNKFLQDSQSEYFNITFVSSMSILLKDMIKGGFG
CCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCC
IGWLPDYSIQEELKNNELMIIPLKDSVLSVDIYLYRSSSRLNAASEGLWNFIKAIDWT
CCCCCCCHHHHHHCCCCEEEEEECCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLIQNIELKWLYDLITLEKYRNFTMAADMRNISQSSLSRRIQTLENTLGFEVFNREMSP
CCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LQLTEKGKLFVLHARSFLDDFEYNIDKIKGTDNIRSKVTIASAHSLAGYIFPKILGNLKN
EEEECCCCEEEEECHHHHHHHHCCHHEECCCCCHHHEEEEEHHHHHHHHHHHHHHHHHHH
YQEKIFHVEAINVNETVDHLRNGKCDFIASFYDDELMNPQFLCHKIFSAKLYLVTAPNHL
HHHHHEEEEEECCHHHHHHHHCCCEEEEEEHHCCCCCCHHHHHHHHHCCEEEEEECCCCC
GRPKFSLEDRSLPLMNYTDDSYMGKKVNKFLQDSQSEYFNITFVSSMSILLKDMIKGGFG
CCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCC
IGWLPDYSIQEELKNNELMIIPLKDSVLSVDIYLYRSSSRLNAASEGLWNFIKAIDWT
CCCCCCCHHHHHHCCCCEEEEEECCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]