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The map label for this gene is rpoB

Identifier: 50083579

GI number: 50083579

Start: 302457

End: 306545

Strand: Direct

Name: rpoB

Synonym: ACIAD0307

Alternate gene names: 50083579

Gene position: 302457-306545 (Clockwise)

Preceding gene: 50083578

Following gene: 50083580

Centisome position: 8.4

GC content: 44.19

Gene sequence:

>4089_bases
ATGGCATACTCATATACCGAAAAGAAACGGATCCGTAAGAATTTTGGTAAATTGCCTAGCGTCATGGACGCTCCATACTT
GCTTTCGATTCAGGTCGACTCGTATAGAACGTTTTTGCAAGATGGCAAATCACCAAAAAATCGCGAAGATATCGGCCTCC
AAGCCGCATTTCGTTCGGTTTTCCCAATAGAAAGTTATTCTGGCAATGCTGCTTTAGAATTTGTTGAGTATGGCCTTGGT
AAACCTGAGTTTGATGTACGTGAATGTATTCTTCGCGGCTCAACTTATGCGGCACCAATGCGCGTTAAAATTCGCTTGAT
CATTAAAGATCGCGAAACGAAATCAATCAAAGATGTTCGTGAACAAGAAGTATACATGGGTGAAATTCCACTCATGACTG
AAAATGGTACCTTTGTGATCAATGGTACCGAGCGTGTAATCGTATCTCAATTACATCGTTCACCAGGCGTATTCTTCGAT
CATGACAAGGGTAAGACTCACTCTAGTGGTAAAGTGTTATATTCAGCACGTATCATTCCTTACCGTGGTTCATGGTTAGA
CTTTGAATTTGATGCCAAAGATTTAGTCTATGTACGTATTGACCGTCGTCGTAAATTACTGGCGAGTGTGATTTTACGTG
CATTGGGTTATAACAATGCTCAGATTCTTGATTTGTTCTATGAAAAAGTGCCGGTATATCTGGACTTTGGTAGTTATCAG
ATTGATCTTGTTCCAGAACGCCTGCGCGGTGAAATGGCACAGTTCGATATCGCCGATAATGATGGCAAAGTCATTGTAGA
ACAAGGCAAACGTATTAATGCACGTCACGTACGTCAAATGGAAGCTTCTGGTTTAACTAAGCTTTCTGTACCTGATGAAT
ATCTATATGAGCGTATTACAGCTGAAGACATTACGTTACGTGATGGTGATGTGATTGCAGCCAATACCTTGCTGAGCCAT
GAAATCATGGTGAAACTCGCTGAAGGTGGCGTAAAACAGTTCAATATCCTTTATACCAACGATATTGATCATGGTTCATT
CGTTGCGGATACTTTGCGTGCAGATACCACAATGGGTCGTGAAGACGCTTTGGTTGAAATCTACAAAGTCATGCGTCCAG
GTGAGCCACCAACGAAAGAAGCGGCTGAGAATTTGTTTAATAACTTGTTCTTCTCATCTGAACGTTATGACTTATCTCCA
GTTGGACGTATGAAGTTCAACCGTCGTTTGGGTCGTCCATACGAAGTCGGTACAGATCAGAAATCTCGCGAAGTTGAAGG
TATTCTCTCGAATGAAGATATCATCGATGTACTGCGTACACTTGTAGAGATTCGTAACGGTAAAGGTGAAGTTGACGATA
TCGATCACTTGGGTAACCGTCGTGTCCGTTCTGTTGGTGAGATGACTGAGAACCAATTCCGTGTAGGTCTGGTTCGTGTT
GAACGTGCAGTGAAAGAACGTTTAAGCCAGGCGGAAACTGACAACTTGTCTCCACAAGATTTGATCAACGCCAAGCCAGT
TGCAGCGGCAATCAAAGAATTCTTTGGTTCAAGCCAATTGTCTCAATTTATGGATCAAAACAACCCATTGTCTGAAATTA
CACACAAACGTCGTGTATCAGCATTGGGACCAGGTGGTTTGACACGTGAACGTGCAGGCTTTGAAGTGCGTGACGTACAT
CAAACACATTATGGTCGTGTATGTCCGATTGAAACACCTGAAGGTCCAAACATTGGTTTGATCAACTCACTTTCTGTATA
TGCCAAAGCCAACGATTTTGGTTTCTTGGAAACACCATATCGTAAAGTTGTTGATGGTCGCGTGAGTGATGATGTTGAAT
ATCTGTCAGCGATTGAAGAAGTAGGTACCGTGATTGCACAGGCAGACTCTGCTGTAGATGCAGACGGTCACTTGATGGAA
GAGATGGTTTCTGTCCGTCATCAAGGCGAATTTGTACGTATGCCGCCTGAAAAAGTAACGCATATGGATGTATCTGCACA
GCAGGTTGTATCTGTCGCGGCATCACTTATTCCATTCCTTGAACACGATGATGCCAACCGTGCATTGATGGGTTCAAACA
TGCAGCGTCAGGCTGTTCCAACTTTGCTTGCCGATAAGCCACTTGTGGGTACCGGTATGGAAGCAAACGTTGCGCGTGAC
TCTGGTGTGTGTGTCATCGCAAAACGTGGCGGGATGATCGAATTTGTTGATGCTTCTCGTGTCGTGATTCGTGTCAACGA
AGAAGAAATGATCGCTGGTGAAGCAGGCGTAGATATCTACAACCTGATCAAGTATACGCGTTCAAACCAGAACACCTGTA
TTAACCAGAAAGTACTGGTGAACCTGGGTGATAAAGTGGGTCGTGGCGATGTGTTGGCAGATGGCCCATCTACCGATGGC
GGTGAGCTGGCACTGGGTCAAAACATGCGCGTTGCGTTCATGACCTGGAATGGTTACAACTATGAAGACTCGATCTTGCT
TTCTGAGCGTGTACTTCAAGAAGACCGTTTAACCTCGATTCACATTCAGGAATTGTCATGTGTTGCGCGTGATACCAAGT
TGGGTGCAGAAGAAATTACTGCCGATATTCCTAACGTCGGTGAAGCGGCACTGTCTAAGCTTGACGAATCAGGTATCGTG
TATATCGGTGCTGAAGTCACTGCGGGTGATATCCTTGTAGGTAAAGTAACACCTAAAGGTGAAACTCAACTTACGCCTGA
AGAAAAACTTCTACGTGCAATCTTTGGTGAAAAAGCGGCAGACGTGAAAGATTCATCTTTACGTGTTCCATCTGGCACCA
AAGGTACCGTGATTGACGTTCAAGTGTTTACACGTGATGGTCTTGAAAAAGATGACCGTGCACTTGCGATTGAAAAAGCA
CAACTTGATGCATACCGCAAAGACTTGAAAGAAGAATATAAAATCTTCGAAGAAGCAGCACGTGAACGTATTGTTCGTCT
GTTGAATGGTCAAGAGTCAAATGGCGGCGGAACCACAAAACGTGGCGACAAGCTGTCTGATGATGTGTTATCTGGTCTTG
AGCTGGTTGATTTGTTAGACATCCAACCAACCGATGAAGGCATTGCAGAGCGTCTCAGCCAGATTCAAGTGTTCTTAAAA
GAAAAGAGCGCAGAGATCGATGAGAAATTTGCAGAGAAAAAACGCAAACTTGCAACAGGTGATGAACTTACAACAGGTGT
GTTGAAAGTTGTTAAAGTTTATCTTGCTGTAAAACGTCGTATTCAGCCTGGTGATAAAATGGCGGGTCGTCACGGGAACA
AGGGTGTTGTATCTAACATTCTGCCTGTAGAAGACATGCCACATGATGCCAATGGTGTGCCTGTTGATGTGGTATTAAAC
CCACTGGGTGTACCGTCACGTATGAACGTGGGTCAGATTCTTGAGACACACTTGGGGCTTGCTGCCAAAGGTTTGGGTGA
GCAAATCGACAAAATGTTGCAACAGCAACGTACGATTGCAGAGCTTCGTATTTTCTTGGACAAAATCTACAACAAGGTAG
GTGGTGAACAGGAAGAACTTGATACCTTGACTGATGAAGAAATTCTGGTACTTGCTGGTAACTTGCGTAAGGGTGTTCCT
TTGGCAACCCCAGTATTTGATGGTGCAGAAGAAGGTCAAATCAAAGAGTTGCTTGAGCTTGCTGAATTGCCACGTACTGG
TCAACAGATTTTGTTTGACGGACGTACAGGTGAACAGTTCGATCGTCCTGTGACTGTCGGTTACATGTACATGCTCAAGT
TGAACCACTTGGTTGATGACAAAATGCATGCGCGTTCAACAGGTTCTTACTCACTTGTTACACAGCAGCCGCTTGGTGGT
AAAGCACAATTCGGTGGTCAGCGTTTCGGTGAGATGGAAGTCTGGGCACTCGAAGCTTACGGTGCAGCTTATACGCTTCA
AGAAATGCTCACGGTGAAATCGGATGACGTTGAAGGTCGTACCCGCATCTATAAGAACATTGTAGATGGCAACCATTATA
TGGATCCAGGTATGCCTGAATCGTTCAACGTATTGACCAAAGAGATCCGTTCTTTAGGTATCAACATTGAACTGAAAAAT
GGTGACTAA

Upstream 100 bases:

>100_bases
AAAATTGCAGCATTTGTAAAAGTGGTGGCCATATCGGCCTGCGTAATTCCATCCAAGCTCGTTCTGCAGGCGAGCCTGGT
TTACTTTCCGAGGACTCCAG

Downstream 100 bases:

>100_bases
GCGTTAAGCTGACTCAGATTTTTCAGGAAAAACAGTATTTGTGACCCAGCCGAGTGAGCGAATGCTCCTCGGTATACGGA
GAAATAAATTGAAAGACTTG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1362; Mature: 1361

Protein sequence:

>1362_residues
MAYSYTEKKRIRKNFGKLPSVMDAPYLLSIQVDSYRTFLQDGKSPKNREDIGLQAAFRSVFPIESYSGNAALEFVEYGLG
KPEFDVRECILRGSTYAAPMRVKIRLIIKDRETKSIKDVREQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFD
HDKGKTHSSGKVLYSARIIPYRGSWLDFEFDAKDLVYVRIDRRRKLLASVILRALGYNNAQILDLFYEKVPVYLDFGSYQ
IDLVPERLRGEMAQFDIADNDGKVIVEQGKRINARHVRQMEASGLTKLSVPDEYLYERITAEDITLRDGDVIAANTLLSH
EIMVKLAEGGVKQFNILYTNDIDHGSFVADTLRADTTMGREDALVEIYKVMRPGEPPTKEAAENLFNNLFFSSERYDLSP
VGRMKFNRRLGRPYEVGTDQKSREVEGILSNEDIIDVLRTLVEIRNGKGEVDDIDHLGNRRVRSVGEMTENQFRVGLVRV
ERAVKERLSQAETDNLSPQDLINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVH
QTHYGRVCPIETPEGPNIGLINSLSVYAKANDFGFLETPYRKVVDGRVSDDVEYLSAIEEVGTVIAQADSAVDADGHLME
EMVSVRHQGEFVRMPPEKVTHMDVSAQQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLLADKPLVGTGMEANVARD
SGVCVIAKRGGMIEFVDASRVVIRVNEEEMIAGEAGVDIYNLIKYTRSNQNTCINQKVLVNLGDKVGRGDVLADGPSTDG
GELALGQNMRVAFMTWNGYNYEDSILLSERVLQEDRLTSIHIQELSCVARDTKLGAEEITADIPNVGEAALSKLDESGIV
YIGAEVTAGDILVGKVTPKGETQLTPEEKLLRAIFGEKAADVKDSSLRVPSGTKGTVIDVQVFTRDGLEKDDRALAIEKA
QLDAYRKDLKEEYKIFEEAARERIVRLLNGQESNGGGTTKRGDKLSDDVLSGLELVDLLDIQPTDEGIAERLSQIQVFLK
EKSAEIDEKFAEKKRKLATGDELTTGVLKVVKVYLAVKRRIQPGDKMAGRHGNKGVVSNILPVEDMPHDANGVPVDVVLN
PLGVPSRMNVGQILETHLGLAAKGLGEQIDKMLQQQRTIAELRIFLDKIYNKVGGEQEELDTLTDEEILVLAGNLRKGVP
LATPVFDGAEEGQIKELLELAELPRTGQQILFDGRTGEQFDRPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGG
KAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVEGRTRIYKNIVDGNHYMDPGMPESFNVLTKEIRSLGINIELKN
GD

Sequences:

>Translated_1362_residues
MAYSYTEKKRIRKNFGKLPSVMDAPYLLSIQVDSYRTFLQDGKSPKNREDIGLQAAFRSVFPIESYSGNAALEFVEYGLG
KPEFDVRECILRGSTYAAPMRVKIRLIIKDRETKSIKDVREQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFD
HDKGKTHSSGKVLYSARIIPYRGSWLDFEFDAKDLVYVRIDRRRKLLASVILRALGYNNAQILDLFYEKVPVYLDFGSYQ
IDLVPERLRGEMAQFDIADNDGKVIVEQGKRINARHVRQMEASGLTKLSVPDEYLYERITAEDITLRDGDVIAANTLLSH
EIMVKLAEGGVKQFNILYTNDIDHGSFVADTLRADTTMGREDALVEIYKVMRPGEPPTKEAAENLFNNLFFSSERYDLSP
VGRMKFNRRLGRPYEVGTDQKSREVEGILSNEDIIDVLRTLVEIRNGKGEVDDIDHLGNRRVRSVGEMTENQFRVGLVRV
ERAVKERLSQAETDNLSPQDLINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVH
QTHYGRVCPIETPEGPNIGLINSLSVYAKANDFGFLETPYRKVVDGRVSDDVEYLSAIEEVGTVIAQADSAVDADGHLME
EMVSVRHQGEFVRMPPEKVTHMDVSAQQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLLADKPLVGTGMEANVARD
SGVCVIAKRGGMIEFVDASRVVIRVNEEEMIAGEAGVDIYNLIKYTRSNQNTCINQKVLVNLGDKVGRGDVLADGPSTDG
GELALGQNMRVAFMTWNGYNYEDSILLSERVLQEDRLTSIHIQELSCVARDTKLGAEEITADIPNVGEAALSKLDESGIV
YIGAEVTAGDILVGKVTPKGETQLTPEEKLLRAIFGEKAADVKDSSLRVPSGTKGTVIDVQVFTRDGLEKDDRALAIEKA
QLDAYRKDLKEEYKIFEEAARERIVRLLNGQESNGGGTTKRGDKLSDDVLSGLELVDLLDIQPTDEGIAERLSQIQVFLK
EKSAEIDEKFAEKKRKLATGDELTTGVLKVVKVYLAVKRRIQPGDKMAGRHGNKGVVSNILPVEDMPHDANGVPVDVVLN
PLGVPSRMNVGQILETHLGLAAKGLGEQIDKMLQQQRTIAELRIFLDKIYNKVGGEQEELDTLTDEEILVLAGNLRKGVP
LATPVFDGAEEGQIKELLELAELPRTGQQILFDGRTGEQFDRPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGG
KAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVEGRTRIYKNIVDGNHYMDPGMPESFNVLTKEIRSLGINIELKN
GD
>Mature_1361_residues
AYSYTEKKRIRKNFGKLPSVMDAPYLLSIQVDSYRTFLQDGKSPKNREDIGLQAAFRSVFPIESYSGNAALEFVEYGLGK
PEFDVRECILRGSTYAAPMRVKIRLIIKDRETKSIKDVREQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDH
DKGKTHSSGKVLYSARIIPYRGSWLDFEFDAKDLVYVRIDRRRKLLASVILRALGYNNAQILDLFYEKVPVYLDFGSYQI
DLVPERLRGEMAQFDIADNDGKVIVEQGKRINARHVRQMEASGLTKLSVPDEYLYERITAEDITLRDGDVIAANTLLSHE
IMVKLAEGGVKQFNILYTNDIDHGSFVADTLRADTTMGREDALVEIYKVMRPGEPPTKEAAENLFNNLFFSSERYDLSPV
GRMKFNRRLGRPYEVGTDQKSREVEGILSNEDIIDVLRTLVEIRNGKGEVDDIDHLGNRRVRSVGEMTENQFRVGLVRVE
RAVKERLSQAETDNLSPQDLINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHQ
THYGRVCPIETPEGPNIGLINSLSVYAKANDFGFLETPYRKVVDGRVSDDVEYLSAIEEVGTVIAQADSAVDADGHLMEE
MVSVRHQGEFVRMPPEKVTHMDVSAQQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLLADKPLVGTGMEANVARDS
GVCVIAKRGGMIEFVDASRVVIRVNEEEMIAGEAGVDIYNLIKYTRSNQNTCINQKVLVNLGDKVGRGDVLADGPSTDGG
ELALGQNMRVAFMTWNGYNYEDSILLSERVLQEDRLTSIHIQELSCVARDTKLGAEEITADIPNVGEAALSKLDESGIVY
IGAEVTAGDILVGKVTPKGETQLTPEEKLLRAIFGEKAADVKDSSLRVPSGTKGTVIDVQVFTRDGLEKDDRALAIEKAQ
LDAYRKDLKEEYKIFEEAARERIVRLLNGQESNGGGTTKRGDKLSDDVLSGLELVDLLDIQPTDEGIAERLSQIQVFLKE
KSAEIDEKFAEKKRKLATGDELTTGVLKVVKVYLAVKRRIQPGDKMAGRHGNKGVVSNILPVEDMPHDANGVPVDVVLNP
LGVPSRMNVGQILETHLGLAAKGLGEQIDKMLQQQRTIAELRIFLDKIYNKVGGEQEELDTLTDEEILVLAGNLRKGVPL
ATPVFDGAEEGQIKELLELAELPRTGQQILFDGRTGEQFDRPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVEGRTRIYKNIVDGNHYMDPGMPESFNVLTKEIRSLGINIELKNG
D

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908505, Length=300, Percent_Identity=29.6666666666667, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI238908503, Length=300, Percent_Identity=29.6666666666667, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI212286172, Length=260, Percent_Identity=29.6153846153846, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI33469941, Length=260, Percent_Identity=29.6153846153846, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI4505941, Length=247, Percent_Identity=29.9595141700405, Blast_Score=114, Evalue=7e-25,
Organism=Escherichia coli, GI1790419, Length=1366, Percent_Identity=70.3513909224012, Blast_Score=1937, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=247, Percent_Identity=30.3643724696356, Blast_Score=113, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17506623, Length=235, Percent_Identity=31.063829787234, Blast_Score=113, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25144348, Length=249, Percent_Identity=32.1285140562249, Blast_Score=112, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324781, Length=249, Percent_Identity=32.5301204819277, Blast_Score=123, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324725, Length=248, Percent_Identity=31.8548387096774, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6325267, Length=248, Percent_Identity=31.4516129032258, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17647877, Length=295, Percent_Identity=28.8135593220339, Blast_Score=115, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136444, Length=247, Percent_Identity=29.1497975708502, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17136446, Length=281, Percent_Identity=30.2491103202847, Blast_Score=107, Evalue=5e-23,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_ACIAD (Q6FF90)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045089.1
- ProteinModelPortal:   Q6FF90
- STRING:   Q6FF90
- GeneID:   2879829
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0307
- NMPDR:   fig|62977.3.peg.722
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   Q6FF90
- ProtClustDB:   PRK00405
- BioCyc:   ASP62977:ACIAD0307-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 151486; Mature: 151355

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSYTEKKRIRKNFGKLPSVMDAPYLLSIQVDSYRTFLQDGKSPKNREDIGLQAAFRSV
CCCCHHHHHHHHHHHCCCCCHHCCCEEEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FPIESYSGNAALEFVEYGLGKPEFDVRECILRGSTYAAPMRVKIRLIIKDRETKSIKDVR
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHH
EQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDKGKTHSSGKVLYSARIIP
HHHHEECCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEE
YRGSWLDFEFDAKDLVYVRIDRRRKLLASVILRALGYNNAQILDLFYEKVPVYLDFGSYQ
ECCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCEE
IDLVPERLRGEMAQFDIADNDGKVIVEQGKRINARHVRQMEASGLTKLSVPDEYLYERIT
EEECCHHHCCCHHEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHC
AEDITLRDGDVIAANTLLSHEIMVKLAEGGVKQFNILYTNDIDHGSFVADTLRADTTMGR
CCCEEECCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCC
EDALVEIYKVMRPGEPPTKEAAENLFNNLFFSSERYDLSPVGRMKFNRRLGRPYEVGTDQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
KSREVEGILSNEDIIDVLRTLVEIRNGKGEVDDIDHLGNRRVRSVGEMTENQFRVGLVRV
CHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ERAVKERLSQAETDNLSPQDLINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEITHKRRVS
HHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHH
ALGPGGLTRERAGFEVRDVHQTHYGRVCPIETPEGPNIGLINSLSVYAKANDFGFLETPY
CCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECEEEEEECCCCCCCCCCH
RKVVDGRVSDDVEYLSAIEEVGTVIAQADSAVDADGHLMEEMVSVRHQGEFVRMPPEKVT
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCHHHHH
HMDVSAQQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLLADKPLVGTGMEANVARD
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
SGVCVIAKRGGMIEFVDASRVVIRVNEEEMIAGEAGVDIYNLIKYTRSNQNTCINQKVLV
CCEEEEEECCCEEEEECCCEEEEEECCHHEECCCCCCHHHHHHHHHCCCCCCCCCCEEEE
NLGDKVGRGDVLADGPSTDGGELALGQNMRVAFMTWNGYNYEDSILLSERVLQEDRLTSI
ECCCCCCCCCEEECCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEE
HIQELSCVARDTKLGAEEITADIPNVGEAALSKLDESGIVYIGAEVTAGDILVGKVTPKG
EHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEECEECCCCEEEEECCCCC
ETQLTPEEKLLRAIFGEKAADVKDSSLRVPSGTKGTVIDVQVFTRDGLEKDDRALAIEKA
CCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCCCCCEEEHHHH
QLDAYRKDLKEEYKIFEEAARERIVRLLNGQESNGGGTTKRGDKLSDDVLSGLELVDLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
IQPTDEGIAERLSQIQVFLKEKSAEIDEKFAEKKRKLATGDELTTGVLKVVKVYLAVKRR
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IQPGDKMAGRHGNKGVVSNILPVEDMPHDANGVPVDVVLNPLGVPSRMNVGQILETHLGL
CCCCHHHCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
AAKGLGEQIDKMLQQQRTIAELRIFLDKIYNKVGGEQEELDTLTDEEILVLAGNLRKGVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEECCCCCCCC
LATPVFDGAEEGQIKELLELAELPRTGQQILFDGRTGEQFDRPVTVGYMYMLKLNHLVDD
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
KMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVEGR
HHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHH
TRIYKNIVDGNHYMDPGMPESFNVLTKEIRSLGINIELKNGD
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCC
>Mature Secondary Structure 
AYSYTEKKRIRKNFGKLPSVMDAPYLLSIQVDSYRTFLQDGKSPKNREDIGLQAAFRSV
CCCHHHHHHHHHHHCCCCCHHCCCEEEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FPIESYSGNAALEFVEYGLGKPEFDVRECILRGSTYAAPMRVKIRLIIKDRETKSIKDVR
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHH
EQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDKGKTHSSGKVLYSARIIP
HHHHEECCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEE
YRGSWLDFEFDAKDLVYVRIDRRRKLLASVILRALGYNNAQILDLFYEKVPVYLDFGSYQ
ECCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCEE
IDLVPERLRGEMAQFDIADNDGKVIVEQGKRINARHVRQMEASGLTKLSVPDEYLYERIT
EEECCHHHCCCHHEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHC
AEDITLRDGDVIAANTLLSHEIMVKLAEGGVKQFNILYTNDIDHGSFVADTLRADTTMGR
CCCEEECCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCC
EDALVEIYKVMRPGEPPTKEAAENLFNNLFFSSERYDLSPVGRMKFNRRLGRPYEVGTDQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
KSREVEGILSNEDIIDVLRTLVEIRNGKGEVDDIDHLGNRRVRSVGEMTENQFRVGLVRV
CHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ERAVKERLSQAETDNLSPQDLINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEITHKRRVS
HHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHH
ALGPGGLTRERAGFEVRDVHQTHYGRVCPIETPEGPNIGLINSLSVYAKANDFGFLETPY
CCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECEEEEEECCCCCCCCCCH
RKVVDGRVSDDVEYLSAIEEVGTVIAQADSAVDADGHLMEEMVSVRHQGEFVRMPPEKVT
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCHHHHH
HMDVSAQQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLLADKPLVGTGMEANVARD
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
SGVCVIAKRGGMIEFVDASRVVIRVNEEEMIAGEAGVDIYNLIKYTRSNQNTCINQKVLV
CCEEEEEECCCEEEEECCCEEEEEECCHHEECCCCCCHHHHHHHHHCCCCCCCCCCEEEE
NLGDKVGRGDVLADGPSTDGGELALGQNMRVAFMTWNGYNYEDSILLSERVLQEDRLTSI
ECCCCCCCCCEEECCCCCCCCCEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEE
HIQELSCVARDTKLGAEEITADIPNVGEAALSKLDESGIVYIGAEVTAGDILVGKVTPKG
EHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHCCCCCEEEEECEECCCCEEEEECCCCC
ETQLTPEEKLLRAIFGEKAADVKDSSLRVPSGTKGTVIDVQVFTRDGLEKDDRALAIEKA
CCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCCCCCEEEHHHH
QLDAYRKDLKEEYKIFEEAARERIVRLLNGQESNGGGTTKRGDKLSDDVLSGLELVDLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
IQPTDEGIAERLSQIQVFLKEKSAEIDEKFAEKKRKLATGDELTTGVLKVVKVYLAVKRR
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IQPGDKMAGRHGNKGVVSNILPVEDMPHDANGVPVDVVLNPLGVPSRMNVGQILETHLGL
CCCCHHHCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
AAKGLGEQIDKMLQQQRTIAELRIFLDKIYNKVGGEQEELDTLTDEEILVLAGNLRKGVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEECCCCCCCC
LATPVFDGAEEGQIKELLELAELPRTGQQILFDGRTGEQFDRPVTVGYMYMLKLNHLVDD
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
KMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVEGR
HHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHH
TRIYKNIVDGNHYMDPGMPESFNVLTKEIRSLGINIELKNGD
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA