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The map label for this gene is algR [H]

Identifier: 50083559

GI number: 50083559

Start: 283912

End: 284652

Strand: Direct

Name: algR [H]

Synonym: ACIAD0285

Alternate gene names: 50083559

Gene position: 283912-284652 (Clockwise)

Preceding gene: 50083558

Following gene: 50083560

Centisome position: 7.89

GC content: 42.24

Gene sequence:

>741_bases
ATGAGGATTCTGATTTGTGATGATGAACCTCTTGCAATTGGACGATTATCACGGTTAGTGATTCAATTGGGTCATGACGT
AGTTGCGACAGCACAAAATGGTCAGCAGGCACTTGAACTGGTTGATGTTTATCAGCCTGATGTAGTGCTGCTGGATATTC
AGATGCCGGATATGAATGGTTTGTTGTGTGCCGAACAGCTCAGCCTGATGGATCCGATGCCAGCCATTATTTTTTGTACG
GCTTATGATGATCATGCTCTCGATGCATTTAAGTCTAAGGCGCAGGGATATTTACTCAAACCCATTGCTCAGCCTGAATT
ACAGCGTGTGCTTGAACAGCTTCCGCGCCTGAATCAGGTACAAATTAATCATATAAAACAAAAAGAAGATATAGACACCT
TGAAGACACAACGACATCAGATCACAGCACGTACTTATCGGGGGGTAGAACTCATTCCGGTCGAAAATATTTATTATTTT
TTAGCCGATCAGAAATACGTCACAGTGCGTCATAAGAATGGCAGTGTACTTATTGATGAAACCTTAAAAGAGCTTGAACT
TGAATTTCAAAATCGGTTTATTCGGATTCATCGTAATGCACTGGTGTCAGTCGATTATCTCGATGGTCTTGAAGTGATTA
GCTCTGGTCAGTATCAAGTGCGTTGCCGTGAGGTGAATGAACGTTTGGCGGTAAGTCGACGTCACCTTCCTTATTTGCGA
GACCGTATGCAAAAAATGTAA

Upstream 100 bases:

>100_bases
GTTGTATACCATCGTAGTAAATTATCCATACCAAACAAAATAATAAGTCGTACCACCTCAAAAAAACGGAACTTATGGGA
GGGCGACAAAGGAGGAAGAA

Downstream 100 bases:

>100_bases
ATTAAGTCGCACATTCATCGTACTAAGGGTGTGAAAGAACATATTTTACTTGCATTTTTAAGCAATCGGGTTAAGTTTAG
AGTCTGTTTTTTATTGATCT

Product: alginate biosynthesis regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRILICDDEPLAIGRLSRLVIQLGHDVVATAQNGQQALELVDVYQPDVVLLDIQMPDMNGLLCAEQLSLMDPMPAIIFCT
AYDDHALDAFKSKAQGYLLKPIAQPELQRVLEQLPRLNQVQINHIKQKEDIDTLKTQRHQITARTYRGVELIPVENIYYF
LADQKYVTVRHKNGSVLIDETLKELELEFQNRFIRIHRNALVSVDYLDGLEVISSGQYQVRCREVNERLAVSRRHLPYLR
DRMQKM

Sequences:

>Translated_246_residues
MRILICDDEPLAIGRLSRLVIQLGHDVVATAQNGQQALELVDVYQPDVVLLDIQMPDMNGLLCAEQLSLMDPMPAIIFCT
AYDDHALDAFKSKAQGYLLKPIAQPELQRVLEQLPRLNQVQINHIKQKEDIDTLKTQRHQITARTYRGVELIPVENIYYF
LADQKYVTVRHKNGSVLIDETLKELELEFQNRFIRIHRNALVSVDYLDGLEVISSGQYQVRCREVNERLAVSRRHLPYLR
DRMQKM
>Mature_246_residues
MRILICDDEPLAIGRLSRLVIQLGHDVVATAQNGQQALELVDVYQPDVVLLDIQMPDMNGLLCAEQLSLMDPMPAIIFCT
AYDDHALDAFKSKAQGYLLKPIAQPELQRVLEQLPRLNQVQINHIKQKEDIDTLKTQRHQITARTYRGVELIPVENIYYF
LADQKYVTVRHKNGSVLIDETLKELELEFQNRFIRIHRNALVSVDYLDGLEVISSGQYQVRCREVNERLAVSRRHLPYLR
DRMQKM

Specific function: Positive regulator of the algD gene, which codes for a GDP-mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=249, Percent_Identity=30.9236947791165, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788724, Length=253, Percent_Identity=26.0869565217391, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28462; Mature: 28462

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILICDDEPLAIGRLSRLVIQLGHDVVATAQNGQQALELVDVYQPDVVLLDIQMPDMNG
CEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCC
LLCAEQLSLMDPMPAIIFCTAYDDHALDAFKSKAQGYLLKPIAQPELQRVLEQLPRLNQV
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCC
QINHIKQKEDIDTLKTQRHQITARTYRGVELIPVENIYYFLADQKYVTVRHKNGSVLIDE
HHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCEEEEEEECCCCEEHHH
TLKELELEFQNRFIRIHRNALVSVDYLDGLEVISSGQYQVRCREVNERLAVSRRHLPYLR
HHHHHHHHHHHHEEEEECCEEEEEEHHCCHHHHCCCCEEEEHHHHHHHHHHHHHCCHHHH
DRMQKM
HHHHCC
>Mature Secondary Structure
MRILICDDEPLAIGRLSRLVIQLGHDVVATAQNGQQALELVDVYQPDVVLLDIQMPDMNG
CEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCC
LLCAEQLSLMDPMPAIIFCTAYDDHALDAFKSKAQGYLLKPIAQPELQRVLEQLPRLNQV
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEECCCCCHHHHHHHHHCCCCCCC
QINHIKQKEDIDTLKTQRHQITARTYRGVELIPVENIYYFLADQKYVTVRHKNGSVLIDE
HHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCEEEEEEECCCCEEHHH
TLKELELEFQNRFIRIHRNALVSVDYLDGLEVISSGQYQVRCREVNERLAVSRRHLPYLR
HHHHHHHHHHHHEEEEECCEEEEEEHHCCHHHHCCCCEEEEHHHHHHHHHHHHHCCHHHH
DRMQKM
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493441; 10984043; 2544550; 8159168 [H]