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The map label for this gene is gluQ

Identifier: 50083549

GI number: 50083549

Start: 272760

End: 273638

Strand: Reverse

Name: gluQ

Synonym: ACIAD0272

Alternate gene names: 50083549

Gene position: 273638-272760 (Counterclockwise)

Preceding gene: 50083550

Following gene: 50083543

Centisome position: 7.6

GC content: 46.76

Gene sequence:

>879_bases
ATGTCTCATCGTCATACTGCTTATGTGGGTCGGTTTGCGCCATCGCCAACCGGCCCCTTGCATTTTGGTTCACTGATTAC
CGCTATTGCAAGCTATTGCGATGCCAAGGTCCATCAAGGTAAATGGCTGGTTCGTATCGAAGATACCGACATCCCGCGAA
TCTATCCTGGCAGTGAAGCACATATTCTTGCTTGTATCGATGCTTTCGGCTTTCAACCTGATGGCGAGATCCTGTTTCAA
CGAGATCGCCTTGATCTCTATGAAAATGTCCTTGAGCAACTCAAGGCTCAAAATCTGGTGTATGCCTGTCAATGCACACG
TAAAATGCTGGGTTCAAATGCCATCTATTCAGGCACCTGTCGTAACCTCAATTTACCCTTTCAAAATCAAGCTATTCGCG
TCAAAGTCAAAGATCAACTGATTTGTTTTGATGATCGCTTGCAAGGTATCCAGTGCAGTAATCTTGCACATGATCTAGGG
GATTTTGTTTTAAAACGGCGGGATGGCATTATCAACTATCAGCTCGCTGTGGTGGTGGATGATTATATGCAAGGCATGAC
CCACGTGGTTCGTGGAGCGGACTTACTGGATAATACCCAACGCCAGATCTGGTTAGGCGACCTTCTTGGTTATCCGCGCT
TACACTATCTGCATTTGCCACTGGCCATGAATGCACAAGGACAGAAACTCTCTAAGCAAAATATGGCAGCAGCCCTGGAT
CTCTCCAAAGCATCCCAATATATACAGCAGTCGCTAGCAGCATTACATCAGCCTGCTGTCGATCTGGACACGCCAGACAG
AATGCTCAAACAAGCTGTAGCACAGTGGCAACTCAATCATATTCCACACCAAACACGCTTAGCAGGGACTTATCTCTAG

Upstream 100 bases:

>100_bases
ATCGGATTACGTCGTTTAGAAGCACGTCCTACAGCCACGCAATGTATTGACTGTAAGACGCTCGCAGAAATCAAAGAGAA
GCAAAATAACGGTTAATACG

Downstream 100 bases:

>100_bases
TACCTTGCCATAGAAAAGCACCCTTCAAATTAGACTAAAAGTGTCCAACTTTCAGGATGCAATTCACAATGGGCGGCTTT
TTTATACTGATTTTTTAGAA

Product: glutamyl-tRNA synthetase

Products: NA

Alternate protein names: Glu-Q-RSs

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSHRHTAYVGRFAPSPTGPLHFGSLITAIASYCDAKVHQGKWLVRIEDTDIPRIYPGSEAHILACIDAFGFQPDGEILFQ
RDRLDLYENVLEQLKAQNLVYACQCTRKMLGSNAIYSGTCRNLNLPFQNQAIRVKVKDQLICFDDRLQGIQCSNLAHDLG
DFVLKRRDGIINYQLAVVVDDYMQGMTHVVRGADLLDNTQRQIWLGDLLGYPRLHYLHLPLAMNAQGQKLSKQNMAAALD
LSKASQYIQQSLAALHQPAVDLDTPDRMLKQAVAQWQLNHIPHQTRLAGTYL

Sequences:

>Translated_292_residues
MSHRHTAYVGRFAPSPTGPLHFGSLITAIASYCDAKVHQGKWLVRIEDTDIPRIYPGSEAHILACIDAFGFQPDGEILFQ
RDRLDLYENVLEQLKAQNLVYACQCTRKMLGSNAIYSGTCRNLNLPFQNQAIRVKVKDQLICFDDRLQGIQCSNLAHDLG
DFVLKRRDGIINYQLAVVVDDYMQGMTHVVRGADLLDNTQRQIWLGDLLGYPRLHYLHLPLAMNAQGQKLSKQNMAAALD
LSKASQYIQQSLAALHQPAVDLDTPDRMLKQAVAQWQLNHIPHQTRLAGTYL
>Mature_291_residues
SHRHTAYVGRFAPSPTGPLHFGSLITAIASYCDAKVHQGKWLVRIEDTDIPRIYPGSEAHILACIDAFGFQPDGEILFQR
DRLDLYENVLEQLKAQNLVYACQCTRKMLGSNAIYSGTCRNLNLPFQNQAIRVKVKDQLICFDDRLQGIQCSNLAHDLGD
FVLKRRDGIINYQLAVVVDDYMQGMTHVVRGADLLDNTQRQIWLGDLLGYPRLHYLHLPLAMNAQGQKLSKQNMAAALDL
SKASQYIQQSLAALHQPAVDLDTPDRMLKQAVAQWQLNHIPHQTRLAGTYL

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily

Homologues:

Organism=Homo sapiens, GI134288884, Length=268, Percent_Identity=34.3283582089552, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI226510925, Length=294, Percent_Identity=44.5578231292517, Blast_Score=234, Evalue=5e-63,
Organism=Escherichia coli, GI1788743, Length=257, Percent_Identity=32.6848249027237, Blast_Score=137, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71993394, Length=278, Percent_Identity=30.5755395683453, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324540, Length=253, Percent_Identity=31.2252964426877, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24665321, Length=279, Percent_Identity=31.5412186379928, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLUQ_ACIAD (Q6FFC0)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045059.1
- ProteinModelPortal:   Q6FFC0
- SMR:   Q6FFC0
- STRING:   Q6FFC0
- GeneID:   2879413
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0272
- NMPDR:   fig|62977.3.peg.613
- eggNOG:   COG0008
- HOGENOM:   HBG628189
- OMA:   IIKRSDG
- PhylomeDB:   Q6FFC0
- ProtClustDB:   PRK05710
- BioCyc:   ASP62977:ACIAD0272-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01428
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR03838

Pfam domain/function: PF00749 tRNA-synt_1c

EC number: NA

Molecular weight: Translated: 32921; Mature: 32790

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 47-47 BINDING 173-173 BINDING 191-191 BINDING 232-232

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHRHTAYVGRFAPSPTGPLHFGSLITAIASYCDAKVHQGKWLVRIEDTDIPRIYPGSEA
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEECCCCCC
HILACIDAFGFQPDGEILFQRDRLDLYENVLEQLKAQNLVYACQCTRKMLGSNAIYSGTC
EEEEEEHHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCC
RNLNLPFQNQAIRVKVKDQLICFDDRLQGIQCSNLAHDLGDFVLKRRDGIINYQLAVVVD
CCCCCCCCCCEEEEEECCEEEEEHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEH
DYMQGMTHVVRGADLLDNTQRQIWLGDLLGYPRLHYLHLPLAMNAQGQKLSKQNMAAALD
HHHHHHHHHHHCCHHHCCCHHHEEEHHHCCCCCEEEEECCEEECCCCCHHHHHHHHHHHH
LSKASQYIQQSLAALHQPAVDLDTPDRMLKQAVAQWQLNHIPHQTRLAGTYL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
SHRHTAYVGRFAPSPTGPLHFGSLITAIASYCDAKVHQGKWLVRIEDTDIPRIYPGSEA
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEECCCCCC
HILACIDAFGFQPDGEILFQRDRLDLYENVLEQLKAQNLVYACQCTRKMLGSNAIYSGTC
EEEEEEHHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCC
RNLNLPFQNQAIRVKVKDQLICFDDRLQGIQCSNLAHDLGDFVLKRRDGIINYQLAVVVD
CCCCCCCCCCEEEEEECCEEEEEHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEH
DYMQGMTHVVRGADLLDNTQRQIWLGDLLGYPRLHYLHLPLAMNAQGQKLSKQNMAAALD
HHHHHHHHHHHCCHHHCCCHHHEEEHHHCCCCCEEEEECCEEECCCCCHHHHHHHHHHHH
LSKASQYIQQSLAALHQPAVDLDTPDRMLKQAVAQWQLNHIPHQTRLAGTYL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA