Click here to switch to the map view.

The map label for this gene is holC [H]

Identifier: 50083530

GI number: 50083530

Start: 250800

End: 251207

Strand: Reverse

Name: holC [H]

Synonym: ACIAD0252

Alternate gene names: 50083530

Gene position: 251207-250800 (Counterclockwise)

Preceding gene: 50083531

Following gene: 50083529

Centisome position: 6.98

GC content: 35.78

Gene sequence:

>408_bases
ATGACTAAAATCAGTTTCTATTTATTTGAAACCAGTCAGGAACGGCAAGTCGAAAGTGCTTGCCGTTTATGCCGAAAACT
CGTGAAACAACAACAAAAGCTATGGTGGTTTTGTCCAGATCTGGAGTTACAAAAGCAGCTTGATGAACGTTTATGGACCT
TTGATCGGGAAAGTTTTATCACTCATGGTATTGATCAACCTCACGCTTTTGTTTGTATTTCAAGCCATTTACCTACCTCG
AAAGAATGGATTGTGTTTAATTTTAACAATCAAGCACTTGAACAAATGAGTGAGTTTAGTCACATTATTGAAATTATTGA
GAATACTGAATCCGCAAAGCAGATTGGACGAGAAAAATTCAAACTTTATCGTCGTTTAGGTGTAGAACCTCGTACTTTTA
AATTATAA

Upstream 100 bases:

>100_bases
GATATTGCAGGAACAGCTTGGCTCTCAGGAACAGCAAAAGGTGCAACAGGTCGTCCTGTACCACTTTTAGTTCAGTTTTT
AGCAAATCGTGTAGGTACGA

Downstream 100 bases:

>100_bases
GTGTTAAACCATGCTGTGGTGTAAGGAGAAATATTGTGGCATTAAATGTCGGGCATGATTTTAAAAAGCGTTGGCTAGAT
GCGCCTGAAGCTGTACGTCA

Product: DNA polymerase III chi

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MTKISFYLFETSQERQVESACRLCRKLVKQQQKLWWFCPDLELQKQLDERLWTFDRESFITHGIDQPHAFVCISSHLPTS
KEWIVFNFNNQALEQMSEFSHIIEIIENTESAKQIGREKFKLYRRLGVEPRTFKL

Sequences:

>Translated_135_residues
MTKISFYLFETSQERQVESACRLCRKLVKQQQKLWWFCPDLELQKQLDERLWTFDRESFITHGIDQPHAFVCISSHLPTS
KEWIVFNFNNQALEQMSEFSHIIEIIENTESAKQIGREKFKLYRRLGVEPRTFKL
>Mature_134_residues
TKISFYLFETSQERQVESACRLCRKLVKQQQKLWWFCPDLELQKQLDERLWTFDRESFITHGIDQPHAFVCISSHLPTSK
EWIVFNFNNQALEQMSEFSHIIEIIENTESAKQIGREKFKLYRRLGVEPRTFKL

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 16274; Mature: 16143

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKISFYLFETSQERQVESACRLCRKLVKQQQKLWWFCPDLELQKQLDERLWTFDRESFI
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCHHHHH
THGIDQPHAFVCISSHLPTSKEWIVFNFNNQALEQMSEFSHIIEIIENTESAKQIGREKF
HCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
KLYRRLGVEPRTFKL
HHHHHHCCCCCCCCC
>Mature Secondary Structure 
TKISFYLFETSQERQVESACRLCRKLVKQQQKLWWFCPDLELQKQLDERLWTFDRESFI
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCHHHHH
THGIDQPHAFVCISSHLPTSKEWIVFNFNNQALEQMSEFSHIIEIIENTESAKQIGREKF
HCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
KLYRRLGVEPRTFKL
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9864319; 10984043 [H]