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The map label for this gene is nahR [H]

Identifier: 50083484

GI number: 50083484

Start: 196911

End: 197858

Strand: Direct

Name: nahR [H]

Synonym: ACIAD0202

Alternate gene names: 50083484

Gene position: 196911-197858 (Clockwise)

Preceding gene: 50083483

Following gene: 50083485

Centisome position: 5.47

GC content: 44.94

Gene sequence:

>948_bases
GTGATTAATCCAGCCAATAAATGGGAAGCACTCGATGCACATCTTCTTCAAGTACTGTATGTATTACTAACCGAAAAAAG
TGTTTCAAATGCGGCAAAACGTCTTAACCAGTCACAACCTGCGATCAGTACTGCCTTAAAAAAGCTACGCGATATCACAG
GGGATCAGTTATTGGTGCGTAGCCGTAATGGAATGACGCCTACAGAACGCGGTGAGTCCCTGCTAGAACCTGTTCGTCAG
GCCTTGGCACAAATCGAACTAATTGCCACTCAGCAGGTTCATTTTAATCCTGCTGAGTCACGTCAAGTCTTTAATATTGC
CGCACCAGATTATCTCAATGCGATTGCATTGGGTGAAGTATTACGCCGTGTTCGTCAAGAAGCACCGCATTGCACCGTGA
TTATGCATTCGATGGCACACGATGTAGATTATACCCATGCGCTTGAAAGTGGGACATACGACGCAGTGATTGGAAACTGG
CCCCAACCACCAGAGTATCTCAGACTGGCACCACTATTTGAAGACGAAGTGGTTTGTCTGATGCGAAAGTCGCATCCGCT
CGCAGCACGTCCATTAACGCTAGAAGATTACCTTCAGGCGGATCATATTGTGCCCACGCCTTATATTGTGGGACAGCGTG
GAGTGATCGACTTATATTTGGCCAAAGAACGAATAAAACGTAATATAGTGGCTTATGTGCCTTATTTCGGCATGATTCCT
TACATGTTGCTACAATTTGACGCGATTTTTTCTGCGCCGCGGTCATTTTCTCGTCATTATAGTGCGTTATTGCCACTCAA
GGTGGTGGATGCGCCCATCAAGTTTCCTAAAATCTCTTATTTTCTGCTTTGGCACGAACGTTTACATCGTTCACAGGAAC
ATCGCTGGTTTCGTGATCTGGTTATTTCTGTACTTCGTAATGATGGCTATGTAAGTTTGAATCAATAG

Upstream 100 bases:

>100_bases
ACTTAAACTGGTGAAAACCGTATCGCACATTTAAAATTTGTCCATATGGTATAAAATTTGAATGAGCTAACTTTGCAATC
ATAATGATCAGGATCTTCAG

Downstream 100 bases:

>100_bases
ATGATCTGCCTTATTCACACTCGTCTGCTTCCGATACGATAATTGGGATCAGACGGGCTTTTATTTTTATTCTATTTTTT
TGTTTTATAACATTTTAATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MINPANKWEALDAHLLQVLYVLLTEKSVSNAAKRLNQSQPAISTALKKLRDITGDQLLVRSRNGMTPTERGESLLEPVRQ
ALAQIELIATQQVHFNPAESRQVFNIAAPDYLNAIALGEVLRRVRQEAPHCTVIMHSMAHDVDYTHALESGTYDAVIGNW
PQPPEYLRLAPLFEDEVVCLMRKSHPLAARPLTLEDYLQADHIVPTPYIVGQRGVIDLYLAKERIKRNIVAYVPYFGMIP
YMLLQFDAIFSAPRSFSRHYSALLPLKVVDAPIKFPKISYFLLWHERLHRSQEHRWFRDLVISVLRNDGYVSLNQ

Sequences:

>Translated_315_residues
MINPANKWEALDAHLLQVLYVLLTEKSVSNAAKRLNQSQPAISTALKKLRDITGDQLLVRSRNGMTPTERGESLLEPVRQ
ALAQIELIATQQVHFNPAESRQVFNIAAPDYLNAIALGEVLRRVRQEAPHCTVIMHSMAHDVDYTHALESGTYDAVIGNW
PQPPEYLRLAPLFEDEVVCLMRKSHPLAARPLTLEDYLQADHIVPTPYIVGQRGVIDLYLAKERIKRNIVAYVPYFGMIP
YMLLQFDAIFSAPRSFSRHYSALLPLKVVDAPIKFPKISYFLLWHERLHRSQEHRWFRDLVISVLRNDGYVSLNQ
>Mature_315_residues
MINPANKWEALDAHLLQVLYVLLTEKSVSNAAKRLNQSQPAISTALKKLRDITGDQLLVRSRNGMTPTERGESLLEPVRQ
ALAQIELIATQQVHFNPAESRQVFNIAAPDYLNAIALGEVLRRVRQEAPHCTVIMHSMAHDVDYTHALESGTYDAVIGNW
PQPPEYLRLAPLFEDEVVCLMRKSHPLAARPLTLEDYLQADHIVPTPYIVGQRGVIDLYLAKERIKRNIVAYVPYFGMIP
YMLLQFDAIFSAPRSFSRHYSALLPLKVVDAPIKFPKISYFLLWHERLHRSQEHRWFRDLVISVLRNDGYVSLNQ

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=306, Percent_Identity=28.7581699346405, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790147, Length=298, Percent_Identity=26.510067114094, Blast_Score=81, Evalue=7e-17,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36039; Mature: 36039

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINPANKWEALDAHLLQVLYVLLTEKSVSNAAKRLNQSQPAISTALKKLRDITGDQLLVR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEE
SRNGMTPTERGESLLEPVRQALAQIELIATQQVHFNPAESRQVFNIAAPDYLNAIALGEV
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEECCCHHHHHHHHHHH
LRRVRQEAPHCTVIMHSMAHDVDYTHALESGTYDAVIGNWPQPPEYLRLAPLFEDEVVCL
HHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCCCEECCCCCCHHHEEECCCCCCHHHHH
MRKSHPLAARPLTLEDYLQADHIVPTPYIVGQRGVIDLYLAKERIKRNIVAYVPYFGMIP
HHCCCCCCCCCCCHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
YMLLQFDAIFSAPRSFSRHYSALLPLKVVDAPIKFPKISYFLLWHERLHRSQEHRWFRDL
HHHHHHHHHHHCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VISVLRNDGYVSLNQ
HHHHHHCCCCEEECC
>Mature Secondary Structure
MINPANKWEALDAHLLQVLYVLLTEKSVSNAAKRLNQSQPAISTALKKLRDITGDQLLVR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEE
SRNGMTPTERGESLLEPVRQALAQIELIATQQVHFNPAESRQVFNIAAPDYLNAIALGEV
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEECCCHHHHHHHHHHH
LRRVRQEAPHCTVIMHSMAHDVDYTHALESGTYDAVIGNWPQPPEYLRLAPLFEDEVVCL
HHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCCCEECCCCCCHHHEEECCCCCCHHHHH
MRKSHPLAARPLTLEDYLQADHIVPTPYIVGQRGVIDLYLAKERIKRNIVAYVPYFGMIP
HHCCCCCCCCCCCHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
YMLLQFDAIFSAPRSFSRHYSALLPLKVVDAPIKFPKISYFLLWHERLHRSQEHRWFRDL
HHHHHHHHHHHCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VISVLRNDGYVSLNQ
HHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]