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The map label for this gene is zur [H]

Identifier: 50083460

GI number: 50083460

Start: 176915

End: 177403

Strand: Reverse

Name: zur [H]

Synonym: ACIAD0176

Alternate gene names: 50083460

Gene position: 177403-176915 (Counterclockwise)

Preceding gene: 50083474

Following gene: 50083459

Centisome position: 4.93

GC content: 42.94

Gene sequence:

>489_bases
ATGAGCTCCTGTTCACACGAACATCACAATGCATTACATGGTGTGCATGACCATCACAATGTGGCTGCTCGTCTCGCTGA
AGCAGAGAGCTTATGTGCTGCAACAGGCGCACGTTTAACACCTTTACGTAAAGAGGTTCTCGGTTTAATCCTCAATGCGT
CAGGTCCAGTGGGTGCTTATGATTTGCTCGCCAAGATTAAAAGTGATACTGACCGCCCAGCTGCACCACCAACTGTATAT
CGCACATTAGACTTCTTATTAGAAAAAGGTCTAATACATAGATTAACTTCTATTAATGCCTATATTCCTTGCTGTCATCC
ACGTGAAGGACACCAAGCCGCATTTTTAATTTGTACAGAATGCCATGTCGTCAAGGAAGCCTCATCTGAAGGTTTGATGA
ATCAGTTGAACCAGCTTGCCAAGTCTGACCAGTTTATTGCGCAACATACGATTATTGAAATTTCTGGAAAATGTCAGCAG
TGCAAATAA

Upstream 100 bases:

>100_bases
TGACTTGTGTTATATTATAACAAATTCGTAAAAACACCTACGCCTAATCGAAACATCTATGAGTTCATGTTAATATTTGG
TAAAAATCTGAGGTTGTCTT

Downstream 100 bases:

>100_bases
GTCCGATAGCGCCCGAACTCATCCGCCTTGAAAATATTTATGTTCATCGCGACGAGCGTGATATTTTAAAAAATATCGAC
TTTTCATTACATCAAAATGA

Product: Zn transport system transcriptional repressor

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSSCSHEHHNALHGVHDHHNVAARLAEAESLCAATGARLTPLRKEVLGLILNASGPVGAYDLLAKIKSDTDRPAAPPTVY
RTLDFLLEKGLIHRLTSINAYIPCCHPREGHQAAFLICTECHVVKEASSEGLMNQLNQLAKSDQFIAQHTIIEISGKCQQ
CK

Sequences:

>Translated_162_residues
MSSCSHEHHNALHGVHDHHNVAARLAEAESLCAATGARLTPLRKEVLGLILNASGPVGAYDLLAKIKSDTDRPAAPPTVY
RTLDFLLEKGLIHRLTSINAYIPCCHPREGHQAAFLICTECHVVKEASSEGLMNQLNQLAKSDQFIAQHTIIEISGKCQQ
CK
>Mature_161_residues
SSCSHEHHNALHGVHDHHNVAARLAEAESLCAATGARLTPLRKEVLGLILNASGPVGAYDLLAKIKSDTDRPAAPPTVYR
TLDFLLEKGLIHRLTSINAYIPCCHPREGHQAAFLICTECHVVKEASSEGLMNQLNQLAKSDQFIAQHTIIEISGKCQQC
K

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=138, Percent_Identity=42.7536231884058, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17650; Mature: 17519

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSCSHEHHNALHGVHDHHNVAARLAEAESLCAATGARLTPLRKEVLGLILNASGPVGAY
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHH
DLLAKIKSDTDRPAAPPTVYRTLDFLLEKGLIHRLTSINAYIPCCHPREGHQAAFLICTE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEHH
CHVVKEASSEGLMNQLNQLAKSDQFIAQHTIIEISGKCQQCK
HHHHHHCCCCHHHHHHHHHHHCCHHHHHHHEEEECCCCCCCC
>Mature Secondary Structure 
SSCSHEHHNALHGVHDHHNVAARLAEAESLCAATGARLTPLRKEVLGLILNASGPVGAY
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHH
DLLAKIKSDTDRPAAPPTVYRTLDFLLEKGLIHRLTSINAYIPCCHPREGHQAAFLICTE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEHH
CHVVKEASSEGLMNQLNQLAKSDQFIAQHTIIEISGKCQQCK
HHHHHHCCCCHHHHHHHHHHHCCHHHHHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]