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The map label for this gene is argS

Identifier: 50083449

GI number: 50083449

Start: 162258

End: 164048

Strand: Reverse

Name: argS

Synonym: ACIAD0164

Alternate gene names: 50083449

Gene position: 164048-162258 (Counterclockwise)

Preceding gene: 50083450

Following gene: 50083448

Centisome position: 4.56

GC content: 43.5

Gene sequence:

>1791_bases
ATGAATACCGCCATACAAGCAGCTCTGGATCATGTAGTGCAATCTCTTCAACAAGAAGGGATTCTTCCTTCGGATTGGAA
TAATAACAGTACCCTTACACGGACCAAAGACCGAAGTCATGGTGACTTTGCATCTAACATTGCCATGGTTGGATCAAAAG
CTGCGGGTATGAAACCACGTGATTTGGCGGAAAAAATTCTGGCCTCTTTGCCAGAAGTCGCCGACATCACTAAGGCTGAA
ATAGCAGGCCCAGGATTTATTAATTTCTTTTTAAATGCCGATCAACGTTTTGCTGTACTCGACCAAATTCAGGCTCAAGG
TCAATATTATGGCCAGACCCAGGTCAATGCCGAGAAAAAAATTCAGGTCGAGTTTGTTTCTGCCAACCCAACGTCTAGCC
TTCATGTCGGACATGGTCGCGGTGCAGCTTATGGCATGACCGTTGCCAATCTACTTGAAGCAACAGGTGCACAAGTAGAT
CGCGAATATTATGTCAACGATGCAGGCCGTCAGATGGATATTCTGGCAACATCGACTTATTTACGCTATTTAGAGCTGTT
AGGTCAGCCATTGGTTTTCCCAAAAAATGCCTATCAAGGTGACTATGTTAAGGAAATCGCACAAAGCATTATCGATAAAG
ATGGCGATGCGTATGTGCGCTCAGTCGCAGATGTTTACCGCAATGTCCCTGAAGATGTGCAATATGCGGAAGAACTTGAT
AGTGAAGGCAATAAAGTCGTTTTATCTGGCGATAAAGAAAAGCATATTGATGGACTGATTGCCAATTCTCAACAGTTGAT
TGGTCAAGGTTATCGTGTTTTTCACCAAGCAGCTTTGAAAGCGATTCTGGATGATATTAAAGATGACCTTGCCGATTTTG
GTGTGACCTTTGATCAATGGTTTAGCGAAGCTTCTTTAACCCAAAAGATCGATGAAGCCTTACAAACCTTAGACCAACGC
GGTTATCTATACGAAAAAGAAGGCAATATCTGGTTCAAGTCGACCAAATTTGGCGATGAAAAAGATCGTGTAGTCAAACG
CCGTAATGGTCAAACCACTTATTTTGCATCTGACATTGCTTATCACCTTGATAAATTACAACGTGGTTACACGCATATTG
TGGATATCTGGGGTTCAGACCATCATGGCTATATTGCTCGTGTCAAAGCAGCAATTGATGCAATGGGGTACGATTCATCC
AAACTGACTGTACTGTTGGTACAATTTGTCAGCCTGTGGCGCGGTGGTGAAATGGTACAGATGTCTTCACGCTCTGGTCA
GTTCGTGACACTGCGTGAACTACGCCAAGAAGTTGGTAATGATGCAGCACGTTTTTATTATGTGATGCGTAAATCTGAGC
AACATATTGATTTTGACCTTGATCTGGCTGTTTCTCAAAGCAAGGACAATGCGGTGTACTACATCCAGTACGCGCATGCA
CGTATTTGCCGAATGCTGGAAAAGGCCAACAGCACTCAGATGCGCTTTAATCAAACACAAGCACGCCAGTTTGCAAACCG
TCTTGACCTAGATGCAGAAACTGAAATTTTGGCCAAATTGGCTGCTTATCCAGATATTTTGGTTCGTGCAGCCAATGCCT
ACGAGCCACATCAGATTGGAAACTATTTAAAAGAACTGGCAGCCCTGTTCCATGGCTGGTACAACGAGCATAAAGTGCTG
ACCGAAGATGTTGAACTTACACAAGCACGCTTGTTGCTTTCAGTAAATGTACAGCAAGTTTTAAGAAATGGTTTAGACTT
ACTGGGTGTGTCTGCACCTGAAGCGATGTAA

Upstream 100 bases:

>100_bases
TGGTGTGATTTAATCGTAGATTCACCACATCCCCCTCACCTAAACCAGTCAAAATTTGCTATATTTAGCGTTTTTCCGCG
AACATTCGTTTTAGATAGAT

Downstream 100 bases:

>100_bases
CGCTTCTAACTAAATCAACACAATTCAGATCTGTTGCATAAAAGCCAAACCTTGTTGTTTCGGCTTTTATGCTATTGGTT
AAGTGGTAGAAGTAAAATAG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MNTAIQAALDHVVQSLQQEGILPSDWNNNSTLTRTKDRSHGDFASNIAMVGSKAAGMKPRDLAEKILASLPEVADITKAE
IAGPGFINFFLNADQRFAVLDQIQAQGQYYGQTQVNAEKKIQVEFVSANPTSSLHVGHGRGAAYGMTVANLLEATGAQVD
REYYVNDAGRQMDILATSTYLRYLELLGQPLVFPKNAYQGDYVKEIAQSIIDKDGDAYVRSVADVYRNVPEDVQYAEELD
SEGNKVVLSGDKEKHIDGLIANSQQLIGQGYRVFHQAALKAILDDIKDDLADFGVTFDQWFSEASLTQKIDEALQTLDQR
GYLYEKEGNIWFKSTKFGDEKDRVVKRRNGQTTYFASDIAYHLDKLQRGYTHIVDIWGSDHHGYIARVKAAIDAMGYDSS
KLTVLLVQFVSLWRGGEMVQMSSRSGQFVTLRELRQEVGNDAARFYYVMRKSEQHIDFDLDLAVSQSKDNAVYYIQYAHA
RICRMLEKANSTQMRFNQTQARQFANRLDLDAETEILAKLAAYPDILVRAANAYEPHQIGNYLKELAALFHGWYNEHKVL
TEDVELTQARLLLSVNVQQVLRNGLDLLGVSAPEAM

Sequences:

>Translated_596_residues
MNTAIQAALDHVVQSLQQEGILPSDWNNNSTLTRTKDRSHGDFASNIAMVGSKAAGMKPRDLAEKILASLPEVADITKAE
IAGPGFINFFLNADQRFAVLDQIQAQGQYYGQTQVNAEKKIQVEFVSANPTSSLHVGHGRGAAYGMTVANLLEATGAQVD
REYYVNDAGRQMDILATSTYLRYLELLGQPLVFPKNAYQGDYVKEIAQSIIDKDGDAYVRSVADVYRNVPEDVQYAEELD
SEGNKVVLSGDKEKHIDGLIANSQQLIGQGYRVFHQAALKAILDDIKDDLADFGVTFDQWFSEASLTQKIDEALQTLDQR
GYLYEKEGNIWFKSTKFGDEKDRVVKRRNGQTTYFASDIAYHLDKLQRGYTHIVDIWGSDHHGYIARVKAAIDAMGYDSS
KLTVLLVQFVSLWRGGEMVQMSSRSGQFVTLRELRQEVGNDAARFYYVMRKSEQHIDFDLDLAVSQSKDNAVYYIQYAHA
RICRMLEKANSTQMRFNQTQARQFANRLDLDAETEILAKLAAYPDILVRAANAYEPHQIGNYLKELAALFHGWYNEHKVL
TEDVELTQARLLLSVNVQQVLRNGLDLLGVSAPEAM
>Mature_596_residues
MNTAIQAALDHVVQSLQQEGILPSDWNNNSTLTRTKDRSHGDFASNIAMVGSKAAGMKPRDLAEKILASLPEVADITKAE
IAGPGFINFFLNADQRFAVLDQIQAQGQYYGQTQVNAEKKIQVEFVSANPTSSLHVGHGRGAAYGMTVANLLEATGAQVD
REYYVNDAGRQMDILATSTYLRYLELLGQPLVFPKNAYQGDYVKEIAQSIIDKDGDAYVRSVADVYRNVPEDVQYAEELD
SEGNKVVLSGDKEKHIDGLIANSQQLIGQGYRVFHQAALKAILDDIKDDLADFGVTFDQWFSEASLTQKIDEALQTLDQR
GYLYEKEGNIWFKSTKFGDEKDRVVKRRNGQTTYFASDIAYHLDKLQRGYTHIVDIWGSDHHGYIARVKAAIDAMGYDSS
KLTVLLVQFVSLWRGGEMVQMSSRSGQFVTLRELRQEVGNDAARFYYVMRKSEQHIDFDLDLAVSQSKDNAVYYIQYAHA
RICRMLEKANSTQMRFNQTQARQFANRLDLDAETEILAKLAAYPDILVRAANAYEPHQIGNYLKELAALFHGWYNEHKVL
TEDVELTQARLLLSVNVQQVLRNGLDLLGVSAPEAM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=617, Percent_Identity=23.5008103727715, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1788184, Length=633, Percent_Identity=24.8025276461295, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71985061, Length=612, Percent_Identity=24.6732026143791, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=572, Percent_Identity=25, Blast_Score=94, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320548, Length=616, Percent_Identity=24.025974025974, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321883, Length=575, Percent_Identity=24.3478260869565, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI18859963, Length=606, Percent_Identity=23.2673267326733, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_ACIAD (Q6FFM0)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_044959.1
- ProteinModelPortal:   Q6FFM0
- STRING:   Q6FFM0
- GeneID:   2878784
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0164
- NMPDR:   fig|62977.3.peg.254
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   ASP62977:ACIAD0164-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 66919; Mature: 66919

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAIQAALDHVVQSLQQEGILPSDWNNNSTLTRTKDRSHGDFASNIAMVGSKAAGMKPR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCHH
DLAEKILASLPEVADITKAEIAGPGFINFFLNADQRFAVLDQIQAQGQYYGQTQVNAEKK
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCE
IQVEFVSANPTSSLHVGHGRGAAYGMTVANLLEATGAQVDREYYVNDAGRQMDILATSTY
EEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCHHHEECCCCCEEEHHHHHHH
LRYLELLGQPLVFPKNAYQGDYVKEIAQSIIDKDGDAYVRSVADVYRNVPEDVQYAEELD
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHC
SEGNKVVLSGDKEKHIDGLIANSQQLIGQGYRVFHQAALKAILDDIKDDLADFGVTFDQW
CCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FSEASLTQKIDEALQTLDQRGYLYEKEGNIWFKSTKFGDEKDRVVKRRNGQTTYFASDIA
HHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCHHHHHHHHCCCCEEEEHHHHH
YHLDKLQRGYTHIVDIWGSDHHGYIARVKAAIDAMGYDSSKLTVLLVQFVSLWRGGEMVQ
HHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEE
MSSRSGQFVTLRELRQEVGNDAARFYYVMRKSEQHIDFDLDLAVSQSKDNAVYYIQYAHA
ECCCCCCEEEHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEHHHH
RICRMLEKANSTQMRFNQTQARQFANRLDLDAETEILAKLAAYPDILVRAANAYEPHQIG
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCCHHHHH
NYLKELAALFHGWYNEHKVLTEDVELTQARLLLSVNVQQVLRNGLDLLGVSAPEAM
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure
MNTAIQAALDHVVQSLQQEGILPSDWNNNSTLTRTKDRSHGDFASNIAMVGSKAAGMKPR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCHH
DLAEKILASLPEVADITKAEIAGPGFINFFLNADQRFAVLDQIQAQGQYYGQTQVNAEKK
HHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCE
IQVEFVSANPTSSLHVGHGRGAAYGMTVANLLEATGAQVDREYYVNDAGRQMDILATSTY
EEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCHHHEECCCCCEEEHHHHHHH
LRYLELLGQPLVFPKNAYQGDYVKEIAQSIIDKDGDAYVRSVADVYRNVPEDVQYAEELD
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHC
SEGNKVVLSGDKEKHIDGLIANSQQLIGQGYRVFHQAALKAILDDIKDDLADFGVTFDQW
CCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FSEASLTQKIDEALQTLDQRGYLYEKEGNIWFKSTKFGDEKDRVVKRRNGQTTYFASDIA
HHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCHHHHHHHHCCCCEEEEHHHHH
YHLDKLQRGYTHIVDIWGSDHHGYIARVKAAIDAMGYDSSKLTVLLVQFVSLWRGGEMVQ
HHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEE
MSSRSGQFVTLRELRQEVGNDAARFYYVMRKSEQHIDFDLDLAVSQSKDNAVYYIQYAHA
ECCCCCCEEEHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEEHHHH
RICRMLEKANSTQMRFNQTQARQFANRLDLDAETEILAKLAAYPDILVRAANAYEPHQIG
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHCCCCCHHHHH
NYLKELAALFHGWYNEHKVLTEDVELTQARLLLSVNVQQVLRNGLDLLGVSAPEAM
HHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA