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The map label for this gene is udg [H]

Identifier: 50083390

GI number: 50083390

Start: 97037

End: 98308

Strand: Direct

Name: udg [H]

Synonym: ACIAD0100

Alternate gene names: 50083390

Gene position: 97037-98308 (Clockwise)

Preceding gene: 50083389

Following gene: 50083391

Centisome position: 2.7

GC content: 41.51

Gene sequence:

>1272_bases
ATGAAAATAGCAATTTTTGGTACTACACTCCATGCAGGTGTGATGGCTGCATTATTGGCAGAACGTGGTAATGACGTTTT
CTGGTGTGCAGATCATGACTATAAAGGTCTTGAAGAGCAAATTGTCTGCCAGACTTATCAGGAACAAGACGTAAATCGTC
TGTTGGTTAAGCAGCGTCAGCTTGGTTTTCTCAAGGATTGTCGTTTTTCTTCTATTCCGCTGGATATTGAAGCTTACTTA
TTTTGTTTTAGCCCAACAGAGTTACAGTTCGCTCTCGAAGTCACCCAGCTTTTAAATATACGTCCGATTATTCATCCGCG
CCTCATGATCAATGGCTCAACCTTTGGCTTGCATGGCACAGAAAAGCTGAAGCAAAATTTGCCTAAAGATCACTGGGTTT
ATTTTCCAGATATGATTCAGGAAGGTAATGCCATCAACAGTGTACTTACTGTAAAACATGTGATTGTTGGTGTGGAATCG
GATTATACCAAAACCATTATGCACGAAATGTTGCGCCCATTTTTTCGTTTCAATCATCAGTATTTGTTTATGCCAATACT
TGATGCCGAATTTACCAAACTGAGTATTTCAGGAATGCTGGCAACACGTATCAGCTACATGAACGATATGGCGCTTGTAG
CAGAGAAGCTTGGCATTGATATTGCTAATGTCAAAGAGGGAATGGCAGCCGATACACGTATTGGTTCGGCTTATCTCTCT
GCAGGTGTAGGATTTGGTGGCGAAAACTTTTCACATGATATCTTGACCCTGTCTAATGTTGTCTCTGACACAGGTGCCCG
TAGTCGTTTATTAGAGCAGGTATGGGAAATCAATGAGCAACAAAAAGAAGTGTTATTTCGCAAGCTCTGGAATTACTATC
ACTGCGATCTTAAAGATAAGGTGGTTGCGATTTGGGGTGCTGCGTTTAAGGAAAATACATCGAATATTCATAATGCTCCA
ATCCATAGCATGTTAACTGCTTTGTGGGCGCAGGGAGCCATTGTAAAACTCCATGATCCACAGGCACTTGAGGAGATTCA
GGCACGGTATGGAAAACGCAATGATCTTATTTTGTGCACTGAACAATATGAAGCCACACGCGGTGCACACGCTTTATGCG
TAATGACCGTATGGAAACAGTACTTGAGTCCAGATTATAAAAAACTTCAACAATTGATGGCACACCCGTTTATTTTGGAC
GGACGTAATGTTTACGATCCAGTTTATATAAAACAGCAAGGGTTTGCCTATGAGGGTATAGGTCGGTTATGA

Upstream 100 bases:

>100_bases
TGTTACATTATGGATTAGAACACCCAAAATTGGGTCATGATTTTAAACAATTGATTAACGAACTCGATTTATAAAAATTT
AGATTGCGGCGCAGAATAGA

Downstream 100 bases:

>100_bases
ACAAAAATATCGAACAATTTCCAAGGAAAACCACGTTGACACCTCAACAAAAACTTGAACAGCTGATGGAACAGCACAAA
ACAGTTCATTTGACTGAATT

Product: UDP-glucose 6-dehydrogenase (Ugd) (Udg)

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKIAIFGTTLHAGVMAALLAERGNDVFWCADHDYKGLEEQIVCQTYQEQDVNRLLVKQRQLGFLKDCRFSSIPLDIEAYL
FCFSPTELQFALEVTQLLNIRPIIHPRLMINGSTFGLHGTEKLKQNLPKDHWVYFPDMIQEGNAINSVLTVKHVIVGVES
DYTKTIMHEMLRPFFRFNHQYLFMPILDAEFTKLSISGMLATRISYMNDMALVAEKLGIDIANVKEGMAADTRIGSAYLS
AGVGFGGENFSHDILTLSNVVSDTGARSRLLEQVWEINEQQKEVLFRKLWNYYHCDLKDKVVAIWGAAFKENTSNIHNAP
IHSMLTALWAQGAIVKLHDPQALEEIQARYGKRNDLILCTEQYEATRGAHALCVMTVWKQYLSPDYKKLQQLMAHPFILD
GRNVYDPVYIKQQGFAYEGIGRL

Sequences:

>Translated_423_residues
MKIAIFGTTLHAGVMAALLAERGNDVFWCADHDYKGLEEQIVCQTYQEQDVNRLLVKQRQLGFLKDCRFSSIPLDIEAYL
FCFSPTELQFALEVTQLLNIRPIIHPRLMINGSTFGLHGTEKLKQNLPKDHWVYFPDMIQEGNAINSVLTVKHVIVGVES
DYTKTIMHEMLRPFFRFNHQYLFMPILDAEFTKLSISGMLATRISYMNDMALVAEKLGIDIANVKEGMAADTRIGSAYLS
AGVGFGGENFSHDILTLSNVVSDTGARSRLLEQVWEINEQQKEVLFRKLWNYYHCDLKDKVVAIWGAAFKENTSNIHNAP
IHSMLTALWAQGAIVKLHDPQALEEIQARYGKRNDLILCTEQYEATRGAHALCVMTVWKQYLSPDYKKLQQLMAHPFILD
GRNVYDPVYIKQQGFAYEGIGRL
>Mature_423_residues
MKIAIFGTTLHAGVMAALLAERGNDVFWCADHDYKGLEEQIVCQTYQEQDVNRLLVKQRQLGFLKDCRFSSIPLDIEAYL
FCFSPTELQFALEVTQLLNIRPIIHPRLMINGSTFGLHGTEKLKQNLPKDHWVYFPDMIQEGNAINSVLTVKHVIVGVES
DYTKTIMHEMLRPFFRFNHQYLFMPILDAEFTKLSISGMLATRISYMNDMALVAEKLGIDIANVKEGMAADTRIGSAYLS
AGVGFGGENFSHDILTLSNVVSDTGARSRLLEQVWEINEQQKEVLFRKLWNYYHCDLKDKVVAIWGAAFKENTSNIHNAP
IHSMLTALWAQGAIVKLHDPQALEEIQARYGKRNDLILCTEQYEATRGAHALCVMTVWKQYLSPDYKKLQQLMAHPFILD
GRNVYDPVYIKQQGFAYEGIGRL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296040443, Length=305, Percent_Identity=27.8688524590164, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4507813, Length=305, Percent_Identity=27.8688524590164, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI296040438, Length=305, Percent_Identity=27.8688524590164, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1788340, Length=266, Percent_Identity=22.1804511278195, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560350, Length=345, Percent_Identity=27.536231884058, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI17136908, Length=340, Percent_Identity=28.2352941176471, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48205; Mature: 48205

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIFGTTLHAGVMAALLAERGNDVFWCADHDYKGLEEQIVCQTYQEQDVNRLLVKQRQ
CEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFLKDCRFSSIPLDIEAYLFCFSPTELQFALEVTQLLNIRPIIHPRLMINGSTFGLHGT
CCHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCEECCCCH
EKLKQNLPKDHWVYFPDMIQEGNAINSVLTVKHVIVGVESDYTKTIMHEMLRPFFRFNHQ
HHHHHCCCCCCEEECHHHHHCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCC
YLFMPILDAEFTKLSISGMLATRISYMNDMALVAEKLGIDIANVKEGMAADTRIGSAYLS
EEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHH
AGVGFGGENFSHDILTLSNVVSDTGARSRLLEQVWEINEQQKEVLFRKLWNYYHCDLKDK
HCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCC
VVAIWGAAFKENTSNIHNAPIHSMLTALWAQGAIVKLHDPQALEEIQARYGKRNDLILCT
EEEEEHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCEEEEE
EQYEATRGAHALCVMTVWKQYLSPDYKKLQQLMAHPFILDGRNVYDPVYIKQQGFAYEGI
CHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCCEEEECCCCCCCCC
GRL
CCC
>Mature Secondary Structure
MKIAIFGTTLHAGVMAALLAERGNDVFWCADHDYKGLEEQIVCQTYQEQDVNRLLVKQRQ
CEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFLKDCRFSSIPLDIEAYLFCFSPTELQFALEVTQLLNIRPIIHPRLMINGSTFGLHGT
CCHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEECCEECCCCH
EKLKQNLPKDHWVYFPDMIQEGNAINSVLTVKHVIVGVESDYTKTIMHEMLRPFFRFNHQ
HHHHHCCCCCCEEECHHHHHCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCC
YLFMPILDAEFTKLSISGMLATRISYMNDMALVAEKLGIDIANVKEGMAADTRIGSAYLS
EEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHH
AGVGFGGENFSHDILTLSNVVSDTGARSRLLEQVWEINEQQKEVLFRKLWNYYHCDLKDK
HCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCC
VVAIWGAAFKENTSNIHNAPIHSMLTALWAQGAIVKLHDPQALEEIQARYGKRNDLILCT
EEEEEHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCEEEEE
EQYEATRGAHALCVMTVWKQYLSPDYKKLQQLMAHPFILDGRNVYDPVYIKQQGFAYEGI
CHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCCEEEECCCCCCCCC
GRL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]