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The map label for this gene is ptk [H]

Identifier: 50083361

GI number: 50083361

Start: 64281

End: 66491

Strand: Reverse

Name: ptk [H]

Synonym: ACIAD0068

Alternate gene names: 50083361

Gene position: 66491-64281 (Counterclockwise)

Preceding gene: 50083362

Following gene: 50083360

Centisome position: 1.85

GC content: 39.53

Gene sequence:

>2211_bases
ATGACGATGAACCAGACGACAAATAATGAAGATACAATAGATTTACGTGAGTTGTTTTTTTCACTGATTGTGCAGTGGAA
ACTTATCTTACTTTGCGTATTACTTAGCATAGTTTTAGCGTTACTTTATTTACGTGTTACATCCGATACTTACTCTGTCG
ATGCTCTCGTGCAAGTTGAAAGTCCTAAAGGCGGTGCTTCAGCAGCACTGTTAGGTCAAGAACTTTCTAACGTTATGGAT
ACGTCTGGACTAGGCCAACAGCTTGCGCAAGCAGAAATTGAGATATTGAGATCACGCTTGGTTGTAGGTACAACCATCGA
GAAATTAAATCTGGATATCACTGTTCAACCTAAAAATGACTCCGTGATTCAACGATTAATTTCAAGCTCAGATTTTAGCA
CTCAATATTCTTCACGTGGCGTACTGGTAGAAAATGATTCAGATCATTTCGATATTCAACAATTTACTGTACCTGAAAAA
TATTTGAACAGCTCACTGCTATTAAATATATCAGAGAACAAGCAGATTACCCTGACAGATCTTGATAAAGAAGAAGTGGT
TTTTAAAGGGCAGTTAAATCAAAACAATATCTTATCTACCCGTGATGGTCTCTGGAAAGTTACTATTTTTGGTAATCCTT
TAGAAGAAGAATATATTGTTACCAAACAAGCACTTCCAACAGCAGTAAATAGCCTCCTAGATAACTTTTCTGCCGCCGAA
CGTGGCAAACAAACAGGTGTCATTGGGCTTAGCTATCAAGGTCATGATAAGACTCAAATTACCAGTGTACTGAATGTTAT
TTTGCAAACCTATAAGCAGCAAAATATTGAACGTAGCTCTGCAGAAAAAGAGCAAACGCTAAAATTTCTAGACAAACAGC
TTCCAGAGCTCAAAAAAGAACTCGATCAGGCCGAGCGTCAATTTAACGTATTTCGTCAGCAGTATAATACAGTCGATGTG
AGTAAAGAATCTGAGCTTTATTTAACTCAGAGTGTCACACTCGAAACACAGAAAGCAGAATTACAGCAAAAGCAAGCTGA
ACTCAGTGCCAAATATACGCCTGAGCATCCAGCCATGCAGGAAATCAATGCGCAACTTGGTGCAATTAATAGTAAGATTA
ATGAGTTAAATGGCACACTTAAACGACTTCCAGACGTACAACGCCAGTATTTACAGCTTTATCGTGATGTCGAAGTCAAA
ACACAGCTCTATACTGCTTTACTCAATACCTACCAAACCCTAAACGTTGCCAAAGCAGGTGAAATTGGCAATGTACGCAT
TGTCGATACAGCGATTGAACCTGTAAAACCAATTAAACCGAAAAAATTGATTATTTTAATCTTATCAATTTTCGTAGGTG
GCTTTATTGGGGTCATGGCGGCACTGTTACGTAAGATGTTGCGTACAGGTATTAAAGATGCATCTCAAATTGAAAATGAG
CTCGATTTTCCTGTATATGCAACTGTTCCACGCTCACCTATTCAGGAAAGCCGCATTAAACTGCTGAAGAAGAAGAAAAA
TATTCCTATTCTTGCCATCAAAAACAGTGATGATATTGCGATTGAGAGCTTGCGTAGTATGCGTACAGCGATTCACTTTG
CACTGGCAAATGCCAAAAATAATGTCATTATGATTGCAGGCCCTGCACCAGAAGTGGGTAAGTCTTTTATTTCGACCAAT
CTTGCTGCGATATTGGCACAAAATAACAAACGTGTATTGCTTATCGATGCAGATATGCGCCGTGGTTATTTGCATAAATA
CTTTAATACAGAAATCAAACCCGGCCTTTCCGAGTATTTGACCGATCAGGCAAGTCTGGAAGACGTTACACATCATTCGG
AAGTGTCTGGGCTCGATATGATCACACGGGGTAAAAGCCCAGCCAATCCTTCAGAAATTCTGAGCTCAGCACAGTTTCAA
GCAATGCTTGAGCGCCTGATGCCGCTTTATGATCATATTCTGATTGATACGCCGCCAGTACTTGCAGTGACCGATGGTAT
TATTATCTCTCAATATTCAGGTGTTAATCTGATTGTTGCACGTCATGCCAAAACGCATATGAAGGAACTTGAGCTGACGG
TTAACCGTTTTGAACAGGCAGGTGTCAAAATCAATGGCTTTATCCTGAATGACATTCAGGCCAGTGCAAGTTATGGCTAC
GGTTATGGCTATAACTATGCTTATGGTTATAAAGCCAGTAAAGACGATTAA

Upstream 100 bases:

>100_bases
ACCCTTATCAGCATGATCAGGCTTTTTTTGATGACACCTTTCAGCTTATCCAGCAATGTATAGCCGACTGGAAAAAGTAC
ATTTAACGTAATTATAGATA

Downstream 100 bases:

>100_bases
TTAGCGATCAAAGCCAGATTTTAGAATCTGGCTTTTTATTGCCAAAAGCAACGCAAAATATAAAAAAATCCACTCGTTTT
TTTCTGCAAACATTATATGC

Product: tyrosine-protein kinase, autophosphorylates

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 736; Mature: 735

Protein sequence:

>736_residues
MTMNQTTNNEDTIDLRELFFSLIVQWKLILLCVLLSIVLALLYLRVTSDTYSVDALVQVESPKGGASAALLGQELSNVMD
TSGLGQQLAQAEIEILRSRLVVGTTIEKLNLDITVQPKNDSVIQRLISSSDFSTQYSSRGVLVENDSDHFDIQQFTVPEK
YLNSSLLLNISENKQITLTDLDKEEVVFKGQLNQNNILSTRDGLWKVTIFGNPLEEEYIVTKQALPTAVNSLLDNFSAAE
RGKQTGVIGLSYQGHDKTQITSVLNVILQTYKQQNIERSSAEKEQTLKFLDKQLPELKKELDQAERQFNVFRQQYNTVDV
SKESELYLTQSVTLETQKAELQQKQAELSAKYTPEHPAMQEINAQLGAINSKINELNGTLKRLPDVQRQYLQLYRDVEVK
TQLYTALLNTYQTLNVAKAGEIGNVRIVDTAIEPVKPIKPKKLIILILSIFVGGFIGVMAALLRKMLRTGIKDASQIENE
LDFPVYATVPRSPIQESRIKLLKKKKNIPILAIKNSDDIAIESLRSMRTAIHFALANAKNNVIMIAGPAPEVGKSFISTN
LAAILAQNNKRVLLIDADMRRGYLHKYFNTEIKPGLSEYLTDQASLEDVTHHSEVSGLDMITRGKSPANPSEILSSAQFQ
AMLERLMPLYDHILIDTPPVLAVTDGIIISQYSGVNLIVARHAKTHMKELELTVNRFEQAGVKINGFILNDIQASASYGY
GYGYNYAYGYKASKDD

Sequences:

>Translated_736_residues
MTMNQTTNNEDTIDLRELFFSLIVQWKLILLCVLLSIVLALLYLRVTSDTYSVDALVQVESPKGGASAALLGQELSNVMD
TSGLGQQLAQAEIEILRSRLVVGTTIEKLNLDITVQPKNDSVIQRLISSSDFSTQYSSRGVLVENDSDHFDIQQFTVPEK
YLNSSLLLNISENKQITLTDLDKEEVVFKGQLNQNNILSTRDGLWKVTIFGNPLEEEYIVTKQALPTAVNSLLDNFSAAE
RGKQTGVIGLSYQGHDKTQITSVLNVILQTYKQQNIERSSAEKEQTLKFLDKQLPELKKELDQAERQFNVFRQQYNTVDV
SKESELYLTQSVTLETQKAELQQKQAELSAKYTPEHPAMQEINAQLGAINSKINELNGTLKRLPDVQRQYLQLYRDVEVK
TQLYTALLNTYQTLNVAKAGEIGNVRIVDTAIEPVKPIKPKKLIILILSIFVGGFIGVMAALLRKMLRTGIKDASQIENE
LDFPVYATVPRSPIQESRIKLLKKKKNIPILAIKNSDDIAIESLRSMRTAIHFALANAKNNVIMIAGPAPEVGKSFISTN
LAAILAQNNKRVLLIDADMRRGYLHKYFNTEIKPGLSEYLTDQASLEDVTHHSEVSGLDMITRGKSPANPSEILSSAQFQ
AMLERLMPLYDHILIDTPPVLAVTDGIIISQYSGVNLIVARHAKTHMKELELTVNRFEQAGVKINGFILNDIQASASYGY
GYGYNYAYGYKASKDD
>Mature_735_residues
TMNQTTNNEDTIDLRELFFSLIVQWKLILLCVLLSIVLALLYLRVTSDTYSVDALVQVESPKGGASAALLGQELSNVMDT
SGLGQQLAQAEIEILRSRLVVGTTIEKLNLDITVQPKNDSVIQRLISSSDFSTQYSSRGVLVENDSDHFDIQQFTVPEKY
LNSSLLLNISENKQITLTDLDKEEVVFKGQLNQNNILSTRDGLWKVTIFGNPLEEEYIVTKQALPTAVNSLLDNFSAAER
GKQTGVIGLSYQGHDKTQITSVLNVILQTYKQQNIERSSAEKEQTLKFLDKQLPELKKELDQAERQFNVFRQQYNTVDVS
KESELYLTQSVTLETQKAELQQKQAELSAKYTPEHPAMQEINAQLGAINSKINELNGTLKRLPDVQRQYLQLYRDVEVKT
QLYTALLNTYQTLNVAKAGEIGNVRIVDTAIEPVKPIKPKKLIILILSIFVGGFIGVMAALLRKMLRTGIKDASQIENEL
DFPVYATVPRSPIQESRIKLLKKKKNIPILAIKNSDDIAIESLRSMRTAIHFALANAKNNVIMIAGPAPEVGKSFISTNL
AAILAQNNKRVLLIDADMRRGYLHKYFNTEIKPGLSEYLTDQASLEDVTHHSEVSGLDMITRGKSPANPSEILSSAQFQA
MLERLMPLYDHILIDTPPVLAVTDGIIISQYSGVNLIVARHAKTHMKELELTVNRFEQAGVKINGFILNDIQASASYGYG
YGYNYAYGYKASKDD

Specific function: May be involved in the production and the transport of exopolysaccharides [H]

COG id: COG3206

COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=730, Percent_Identity=37.2602739726027, Blast_Score=463, Evalue=1e-131,
Organism=Escherichia coli, GI1787216, Length=724, Percent_Identity=36.4640883977901, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 82280; Mature: 82149

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNQTTNNEDTIDLRELFFSLIVQWKLILLCVLLSIVLALLYLRVTSDTYSVDALVQVE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
SPKGGASAALLGQELSNVMDTSGLGQQLAQAEIEILRSRLVVGTTIEKLNLDITVQPKND
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCH
SVIQRLISSSDFSTQYSSRGVLVENDSDHFDIQQFTVPEKYLNSSLLLNISENKQITLTD
HHHHHHHCCCCCCCHHCCCCEEEECCCCCCCCCEEECCHHHCCCEEEEEECCCCEEEEEE
LDKEEVVFKGQLNQNNILSTRDGLWKVTIFGNPLEEEYIVTKQALPTAVNSLLDNFSAAE
CCCCCEEEECCCCCCCCEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RGKQTGVIGLSYQGHDKTQITSVLNVILQTYKQQNIERSSAEKEQTLKFLDKQLPELKKE
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LDQAERQFNVFRQQYNTVDVSKESELYLTQSVTLETQKAELQQKQAELSAKYTPEHPAMQ
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCHHH
EINAQLGAINSKINELNGTLKRLPDVQRQYLQLYRDVEVKTQLYTALLNTYQTLNVAKAG
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCC
EIGNVRIVDTAIEPVKPIKPKKLIILILSIFVGGFIGVMAALLRKMLRTGIKDASQIENE
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LDFPVYATVPRSPIQESRIKLLKKKKNIPILAIKNSDDIAIESLRSMRTAIHFALANAKN
CCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
NVIMIAGPAPEVGKSFISTNLAAILAQNNKRVLLIDADMRRGYLHKYFNTEIKPGLSEYL
CEEEEECCCCHHHHHHHHHHHHHEEECCCCEEEEEECCHHHHHHHHHHCCCCCCCHHHHH
TDQASLEDVTHHSEVSGLDMITRGKSPANPSEILSSAQFQAMLERLMPLYDHILIDTPPV
CCHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LAVTDGIIISQYSGVNLIVARHAKTHMKELELTVNRFEQAGVKINGFILNDIQASASYGY
EEEECCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHCCCCCC
GYGYNYAYGYKASKDD
CCCCCCEECCCCCCCC
>Mature Secondary Structure 
TMNQTTNNEDTIDLRELFFSLIVQWKLILLCVLLSIVLALLYLRVTSDTYSVDALVQVE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
SPKGGASAALLGQELSNVMDTSGLGQQLAQAEIEILRSRLVVGTTIEKLNLDITVQPKND
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCH
SVIQRLISSSDFSTQYSSRGVLVENDSDHFDIQQFTVPEKYLNSSLLLNISENKQITLTD
HHHHHHHCCCCCCCHHCCCCEEEECCCCCCCCCEEECCHHHCCCEEEEEECCCCEEEEEE
LDKEEVVFKGQLNQNNILSTRDGLWKVTIFGNPLEEEYIVTKQALPTAVNSLLDNFSAAE
CCCCCEEEECCCCCCCCEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RGKQTGVIGLSYQGHDKTQITSVLNVILQTYKQQNIERSSAEKEQTLKFLDKQLPELKKE
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LDQAERQFNVFRQQYNTVDVSKESELYLTQSVTLETQKAELQQKQAELSAKYTPEHPAMQ
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCHHH
EINAQLGAINSKINELNGTLKRLPDVQRQYLQLYRDVEVKTQLYTALLNTYQTLNVAKAG
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCC
EIGNVRIVDTAIEPVKPIKPKKLIILILSIFVGGFIGVMAALLRKMLRTGIKDASQIENE
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LDFPVYATVPRSPIQESRIKLLKKKKNIPILAIKNSDDIAIESLRSMRTAIHFALANAKN
CCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
NVIMIAGPAPEVGKSFISTNLAAILAQNNKRVLLIDADMRRGYLHKYFNTEIKPGLSEYL
CEEEEECCCCHHHHHHHHHHHHHEEECCCCEEEEEECCHHHHHHHHHHCCCCCCCHHHHH
TDQASLEDVTHHSEVSGLDMITRGKSPANPSEILSSAQFQAMLERLMPLYDHILIDTPPV
CCHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LAVTDGIIISQYSGVNLIVARHAKTHMKELELTVNRFEQAGVKINGFILNDIQASASYGY
EEEECCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHCCCCCC
GYGYNYAYGYKASKDD
CCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9434192; 8683591; 10069388 [H]