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The map label for this gene is yheS [H]

Identifier: 50083304

GI number: 50083304

Start: 7336

End: 9270

Strand: Reverse

Name: yheS [H]

Synonym: ACIAD0007

Alternate gene names: 50083304

Gene position: 9270-7336 (Counterclockwise)

Preceding gene: 50083308

Following gene: 50083302

Centisome position: 0.26

GC content: 45.37

Gene sequence:

>1935_bases
ATGATTCAACTCGACCAATTTTCAGTTCGCCGTGGCGGACGAGTCCTCTTTCAAAAAGCATCGATGCAATTGCATCCAGG
CTGGAAAATTGGTTTAACTGGTGTCAATGGTGCTGGTAAATCGACCCTATTTTCTGCACTTCTGGGTGGAATTGAATCGG
ATAGTGGTAGCTTGAGTCGTCCGAATGTCTGGACTGTGGCACACATGGCACAAGAAATTAAAGCGCTGAATATGAAAGCG
ATTGATTTCGTCTTGTCTGGCGATGAAGAGTACTGGACCATTCAGCATCAGCTTGAACATCCAGAACAGCTTAGCGACAA
CGAGTTGGCTCACCTTTATAGTCGTTTTGATGAAATTAACGGTTATGCAGCAGCGGCTAAAGCATCCCAGCTTATGGCAG
GTTTAGGTTTTTTTGAATATCAATCGCAATATGATGTTGCCAGCTTCTCTGGCGGTTGGCGGATGCGGTTGAATCTGGCG
CGTACCCTGATGAGTCGCTCAGATTTACTCTTACTCGACGAACCAACCAACCATTTGGACTTGGACGCGATTTTGTGGCT
TGAAGACTGGTTGAAAGCCTATGAAGGAACACTGGTTCTGATTTCGCATGACCGTGATTTTCTTGATGCCATTACTGATC
ATATTTTACATATCGAAAATCAGCAGTTAACACTTTATACAGGTAATTATTCAACCTTCGAAACCACACGTGCAGAACGT
TTGGCGCAGCAACAGCAAGCGTTTGAAAAACAGCAAGAGACGCGCGCGCACTTACAAAAATATATTGATCGTTTTAAGGC
ACAAGCCACTAAGGCTCGTCAAGCACAAAGCCGTATTAAACAATTAGAACGCATGCAAGAACTGGCACCTGCACATGTCG
ATACGCCTTTCACCTTTAGCTTTCGTGAACCAAGCAAAATGAGCTCGCCGCTGTTGGCACTTGAACACGCCGACATTGGT
TATGGCGACAAATTGATTGTGACCAATGTCAATTTGCAAATTACCCCGACCAGCCGGATTGGTCTGCTCGGAATGAACGG
CGCGGGTAAATCGACACTGATTAAATCTCTGGTGGGTGATTTGGCGCTATTGCGTGGCACACGTTATGCCTCAGAGCTGC
TCAATATCGGTTACTTTGCCCAGCATCAAATGGATGCTTTGGATGGATCAGCCAGTCCAATGCTACAACTGTCACGTATT
GCAGATAAAAAAATCAGCGAAGCAACACTACGTGCTTTTCTGGGCAGCTTTGGTTTTAGCGGCGAACGCATGGATACGCC
GAGCGAGAGTTTTTCGGGTGGCGAACGTGCTCGACTGGCACTGGCATTGATTGTCTGGCAACGTCCCAATGTTTTAATTT
TAGATGAACCGACCAACCATCTAGATTTAGATATGCGTCATGCGCTAACCATGGCATTACAGGACTTTGAAGGTGCCGTG
GTTTTGGTATCACATGAGCGTCAATTGATCGCCAGCGTCTGCGATGAGCTGATTCTGGTTCATAATGGCAGCAGTCGCGA
TTTTGATGGTGATCTACATGATTATGCGAACTGGTTACGTCAGGCACGTAATGACATGATGAAGCAAGGACAACAGCCTA
CCGCGCCTATTCAATCTAAAGTTGAAGCGCAACCTGTCATCTCTAAACTGGACAAAGAAGCCCAACGCAAAGAAGCCGCG
AAACGTCGCGAACAAACGCGTCCGATTCGTAAAAATATTGAAAAATGTGAAAGTCAGGTTGAGCGCTTACAAAAACGTTT
AGCGGAAATCGAAACCTTACTCGGTGATAGCTCACTTTACGATGCCGATCGTAAAAATGATTTGTTAAAACTCATGAATG
AACAAAGCGATTCAAAACAGGAACTGGAGCAGGCGGAAGAACAAATGCTTGAATTGATGATGCAACTCGAAGAGCTCGAA
AGTTTATTTGATTAA

Upstream 100 bases:

>100_bases
ATCACTTATTCTCAGGCTGACTTGATACTTAAATTTTTGTCTTCGTGTTCGTATATCTTTAGAATAGCGCTACTGTTCTC
TGCATAGCGTCAATTTCTCC

Downstream 100 bases:

>100_bases
TTTACAATCCTGGGCTGTAATCTATTGCAGGATTTACAGCCCGAAACATTTAATTGCCCGCTGTTACAGCTTTATATTTT
TTAATCACTTTTCAAAACCC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MIQLDQFSVRRGGRVLFQKASMQLHPGWKIGLTGVNGAGKSTLFSALLGGIESDSGSLSRPNVWTVAHMAQEIKALNMKA
IDFVLSGDEEYWTIQHQLEHPEQLSDNELAHLYSRFDEINGYAAAAKASQLMAGLGFFEYQSQYDVASFSGGWRMRLNLA
RTLMSRSDLLLLDEPTNHLDLDAILWLEDWLKAYEGTLVLISHDRDFLDAITDHILHIENQQLTLYTGNYSTFETTRAER
LAQQQQAFEKQQETRAHLQKYIDRFKAQATKARQAQSRIKQLERMQELAPAHVDTPFTFSFREPSKMSSPLLALEHADIG
YGDKLIVTNVNLQITPTSRIGLLGMNGAGKSTLIKSLVGDLALLRGTRYASELLNIGYFAQHQMDALDGSASPMLQLSRI
ADKKISEATLRAFLGSFGFSGERMDTPSESFSGGERARLALALIVWQRPNVLILDEPTNHLDLDMRHALTMALQDFEGAV
VLVSHERQLIASVCDELILVHNGSSRDFDGDLHDYANWLRQARNDMMKQGQQPTAPIQSKVEAQPVISKLDKEAQRKEAA
KRREQTRPIRKNIEKCESQVERLQKRLAEIETLLGDSSLYDADRKNDLLKLMNEQSDSKQELEQAEEQMLELMMQLEELE
SLFD

Sequences:

>Translated_644_residues
MIQLDQFSVRRGGRVLFQKASMQLHPGWKIGLTGVNGAGKSTLFSALLGGIESDSGSLSRPNVWTVAHMAQEIKALNMKA
IDFVLSGDEEYWTIQHQLEHPEQLSDNELAHLYSRFDEINGYAAAAKASQLMAGLGFFEYQSQYDVASFSGGWRMRLNLA
RTLMSRSDLLLLDEPTNHLDLDAILWLEDWLKAYEGTLVLISHDRDFLDAITDHILHIENQQLTLYTGNYSTFETTRAER
LAQQQQAFEKQQETRAHLQKYIDRFKAQATKARQAQSRIKQLERMQELAPAHVDTPFTFSFREPSKMSSPLLALEHADIG
YGDKLIVTNVNLQITPTSRIGLLGMNGAGKSTLIKSLVGDLALLRGTRYASELLNIGYFAQHQMDALDGSASPMLQLSRI
ADKKISEATLRAFLGSFGFSGERMDTPSESFSGGERARLALALIVWQRPNVLILDEPTNHLDLDMRHALTMALQDFEGAV
VLVSHERQLIASVCDELILVHNGSSRDFDGDLHDYANWLRQARNDMMKQGQQPTAPIQSKVEAQPVISKLDKEAQRKEAA
KRREQTRPIRKNIEKCESQVERLQKRLAEIETLLGDSSLYDADRKNDLLKLMNEQSDSKQELEQAEEQMLELMMQLEELE
SLFD
>Mature_644_residues
MIQLDQFSVRRGGRVLFQKASMQLHPGWKIGLTGVNGAGKSTLFSALLGGIESDSGSLSRPNVWTVAHMAQEIKALNMKA
IDFVLSGDEEYWTIQHQLEHPEQLSDNELAHLYSRFDEINGYAAAAKASQLMAGLGFFEYQSQYDVASFSGGWRMRLNLA
RTLMSRSDLLLLDEPTNHLDLDAILWLEDWLKAYEGTLVLISHDRDFLDAITDHILHIENQQLTLYTGNYSTFETTRAER
LAQQQQAFEKQQETRAHLQKYIDRFKAQATKARQAQSRIKQLERMQELAPAHVDTPFTFSFREPSKMSSPLLALEHADIG
YGDKLIVTNVNLQITPTSRIGLLGMNGAGKSTLIKSLVGDLALLRGTRYASELLNIGYFAQHQMDALDGSASPMLQLSRI
ADKKISEATLRAFLGSFGFSGERMDTPSESFSGGERARLALALIVWQRPNVLILDEPTNHLDLDMRHALTMALQDFEGAV
VLVSHERQLIASVCDELILVHNGSSRDFDGDLHDYANWLRQARNDMMKQGQQPTAPIQSKVEAQPVISKLDKEAQRKEAA
KRREQTRPIRKNIEKCESQVERLQKRLAEIETLLGDSSLYDADRKNDLLKLMNEQSDSKQELEQAEEQMLELMMQLEELE
SLFD

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=531, Percent_Identity=40.6779661016949, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI27881506, Length=527, Percent_Identity=34.3453510436433, Blast_Score=308, Evalue=2e-83,
Organism=Homo sapiens, GI10947137, Length=527, Percent_Identity=34.3453510436433, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI10947135, Length=548, Percent_Identity=34.3065693430657, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI69354671, Length=548, Percent_Identity=34.1240875912409, Blast_Score=263, Evalue=4e-70,
Organism=Homo sapiens, GI150417984, Length=204, Percent_Identity=31.3725490196078, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI45446740, Length=339, Percent_Identity=25.6637168141593, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI47078218, Length=339, Percent_Identity=25.6637168141593, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789751, Length=641, Percent_Identity=51.4820592823713, Blast_Score=651, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=524, Percent_Identity=32.4427480916031, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI1787182, Length=635, Percent_Identity=29.7637795275591, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI2367384, Length=542, Percent_Identity=30.0738007380074, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87081782, Length=540, Percent_Identity=27.037037037037, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788165, Length=198, Percent_Identity=29.2929292929293, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788506, Length=563, Percent_Identity=22.9129662522202, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787029, Length=204, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787758, Length=193, Percent_Identity=31.6062176165803, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786975, Length=513, Percent_Identity=24.3664717348928, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787772, Length=149, Percent_Identity=30.8724832214765, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=529, Percent_Identity=38.3742911153119, Blast_Score=333, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17559834, Length=542, Percent_Identity=32.4723247232472, Blast_Score=307, Evalue=9e-84,
Organism=Caenorhabditis elegans, GI17555318, Length=534, Percent_Identity=33.8951310861423, Blast_Score=306, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17565586, Length=210, Percent_Identity=28.0952380952381, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321121, Length=551, Percent_Identity=36.1161524500907, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6320874, Length=536, Percent_Identity=33.2089552238806, Blast_Score=296, Evalue=7e-81,
Organism=Saccharomyces cerevisiae, GI6325030, Length=379, Percent_Identity=30.3430079155673, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6324314, Length=380, Percent_Identity=29.2105263157895, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6323278, Length=378, Percent_Identity=28.3068783068783, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24666836, Length=526, Percent_Identity=40.4942965779468, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24642252, Length=529, Percent_Identity=37.4291115311909, Blast_Score=343, Evalue=3e-94,
Organism=Drosophila melanogaster, GI18859989, Length=529, Percent_Identity=37.4291115311909, Blast_Score=343, Evalue=3e-94,
Organism=Drosophila melanogaster, GI24641342, Length=533, Percent_Identity=32.6454033771107, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24643674, Length=221, Percent_Identity=29.8642533936652, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221512771, Length=199, Percent_Identity=32.1608040201005, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI116007184, Length=195, Percent_Identity=31.2820512820513, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221500365, Length=195, Percent_Identity=31.2820512820513, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72753; Mature: 72753

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQLDQFSVRRGGRVLFQKASMQLHPGWKIGLTGVNGAGKSTLFSALLGGIESDSGSLSR
CCCCCCHHHHCCCCEEEEECCCEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCC
PNVWTVAHMAQEIKALNMKAIDFVLSGDEEYWTIQHQLEHPEQLSDNELAHLYSRFDEIN
CCHHHHHHHHHHHHHHCHHHEEEEECCCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHC
GYAAAAKASQLMAGLGFFEYQSQYDVASFSGGWRMRLNLARTLMSRSDLLLLDEPTNHLD
CHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCC
LDAILWLEDWLKAYEGTLVLISHDRDFLDAITDHILHIENQQLTLYTGNYSTFETTRAER
HHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHEEECCCEEEEEECCCCCHHHHHHHH
LAQQQQAFEKQQETRAHLQKYIDRFKAQATKARQAQSRIKQLERMQELAPAHVDTPFTFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
FREPSKMSSPLLALEHADIGYGDKLIVTNVNLQITPTSRIGLLGMNGAGKSTLIKSLVGD
CCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
LALLRGTRYASELLNIGYFAQHQMDALDGSASPMLQLSRIADKKISEATLRAFLGSFGFS
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GERMDTPSESFSGGERARLALALIVWQRPNVLILDEPTNHLDLDMRHALTMALQDFEGAV
CCCCCCCCHHCCCCHHHHHEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VLVSHERQLIASVCDELILVHNGSSRDFDGDLHDYANWLRQARNDMMKQGQQPTAPIQSK
EEEECHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VEAQPVISKLDKEAQRKEAAKRREQTRPIRKNIEKCESQVERLQKRLAEIETLLGDSSLY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
DADRKNDLLKLMNEQSDSKQELEQAEEQMLELMMQLEELESLFD
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQLDQFSVRRGGRVLFQKASMQLHPGWKIGLTGVNGAGKSTLFSALLGGIESDSGSLSR
CCCCCCHHHHCCCCEEEEECCCEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCC
PNVWTVAHMAQEIKALNMKAIDFVLSGDEEYWTIQHQLEHPEQLSDNELAHLYSRFDEIN
CCHHHHHHHHHHHHHHCHHHEEEEECCCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHC
GYAAAAKASQLMAGLGFFEYQSQYDVASFSGGWRMRLNLARTLMSRSDLLLLDEPTNHLD
CHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCC
LDAILWLEDWLKAYEGTLVLISHDRDFLDAITDHILHIENQQLTLYTGNYSTFETTRAER
HHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHEEECCCEEEEEECCCCCHHHHHHHH
LAQQQQAFEKQQETRAHLQKYIDRFKAQATKARQAQSRIKQLERMQELAPAHVDTPFTFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
FREPSKMSSPLLALEHADIGYGDKLIVTNVNLQITPTSRIGLLGMNGAGKSTLIKSLVGD
CCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
LALLRGTRYASELLNIGYFAQHQMDALDGSASPMLQLSRIADKKISEATLRAFLGSFGFS
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GERMDTPSESFSGGERARLALALIVWQRPNVLILDEPTNHLDLDMRHALTMALQDFEGAV
CCCCCCCCHHCCCCHHHHHEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VLVSHERQLIASVCDELILVHNGSSRDFDGDLHDYANWLRQARNDMMKQGQQPTAPIQSK
EEEECHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
VEAQPVISKLDKEAQRKEAAKRREQTRPIRKNIEKCESQVERLQKRLAEIETLLGDSSLY
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHC
DADRKNDLLKLMNEQSDSKQELEQAEEQMLELMMQLEELESLFD
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]