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The map label for this gene is ycbL [H]

Identifier: 49481473

GI number: 49481473

Start: 4334502

End: 4335194

Strand: Reverse

Name: ycbL [H]

Synonym: BT9727_4272

Alternate gene names: 49481473

Gene position: 4335194-4334502 (Counterclockwise)

Preceding gene: 49481626

Following gene: 49481463

Centisome position: 82.77

GC content: 34.63

Gene sequence:

>693_bases
ATGTCACATCATATTTTATTAGTTGAAGATGATCTCTCAATTCAAGAGATGGTGGAAAAGTATTTAGTGAAGGAAGGCTT
TCAAGTTACAATTGCATCTGACGGAGAAGAAGGGGTAAACACATATTTAAAAGGTTCATTTGATTTGATTATCCTCGACA
TTATGATGCCAAAGCTAGATGGCTTAGAGGTTGTACGTATTATTCGTGAAAAAAGTGCCGTTCCGATTTTAATGATGTCA
GCAAAAGATACAGATGTTGATAAAGCTGTTGGATTAGGACTTGGAGCAGATGATTACATTTGTAAGCCATTTTCTATGAT
TGAATTAGCTGCACGTGTAAAGGCGGGTATTCGAAGATCTACGAAATATTCGGCTACAGAAACAACAGAAAAGATGATTC
AAATTGGTGATTTAACGATTGATCCAATTAATTTTACTGTGGAAAAAAACGGAAAGCCTCTCAAACTGACTTTAAAAGAA
TTTGAGATTCTAAAACTGTTTGTAAAGAATCAAAATCGTGTATTTACAAAGGCACAAATATATACGCTAATTTGGAACGA
AGAGTATTACGGTGACGATAACGTTATTAATGTTCATATGAGAAGGTTGCGTGAGAAAATCGAAAGTGATCCATCTAATC
CAGAATATATTAAAACGTTATGGGGCATCGGCTATAAGCTGGAAGTGATGTAA

Upstream 100 bases:

>100_bases
AAGGAAGGGAAGTTGGTTTGAAAATTCATATATTTGTTTCAAGTCTGTAGTAGTTACGATACAATTGAATTGTTAACGTT
TGTAAAAAGGGGATAGACAT

Downstream 100 bases:

>100_bases
TATGATTAATTTGTTAATAGGTATTATTTTTATATTGTTATGTGTCATTTATATACAATATAAAATGAGGAAAAATAGTA
ACAAAAATTTGAGATACACA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSHHILLVEDDLSIQEMVEKYLVKEGFQVTIASDGEEGVNTYLKGSFDLIILDIMMPKLDGLEVVRIIREKSAVPILMMS
AKDTDVDKAVGLGLGADDYICKPFSMIELAARVKAGIRRSTKYSATETTEKMIQIGDLTIDPINFTVEKNGKPLKLTLKE
FEILKLFVKNQNRVFTKAQIYTLIWNEEYYGDDNVINVHMRRLREKIESDPSNPEYIKTLWGIGYKLEVM

Sequences:

>Translated_230_residues
MSHHILLVEDDLSIQEMVEKYLVKEGFQVTIASDGEEGVNTYLKGSFDLIILDIMMPKLDGLEVVRIIREKSAVPILMMS
AKDTDVDKAVGLGLGADDYICKPFSMIELAARVKAGIRRSTKYSATETTEKMIQIGDLTIDPINFTVEKNGKPLKLTLKE
FEILKLFVKNQNRVFTKAQIYTLIWNEEYYGDDNVINVHMRRLREKIESDPSNPEYIKTLWGIGYKLEVM
>Mature_229_residues
SHHILLVEDDLSIQEMVEKYLVKEGFQVTIASDGEEGVNTYLKGSFDLIILDIMMPKLDGLEVVRIIREKSAVPILMMSA
KDTDVDKAVGLGLGADDYICKPFSMIELAARVKAGIRRSTKYSATETTEKMIQIGDLTIDPINFTVEKNGKPLKLTLKEF
EILKLFVKNQNRVFTKAQIYTLIWNEEYYGDDNVINVHMRRLREKIESDPSNPEYIKTLWGIGYKLEVM

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=36.5638766519824, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=38.9380530973451, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=37.280701754386, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=34.7826086956522, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.0357142857143, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=34.2105263157895, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=31.7391304347826, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=32.5892857142857, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=30.5676855895196, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=32.1428571428571, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=31.140350877193, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=32.5991189427313, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=29.9559471365639, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790299, Length=142, Percent_Identity=29.5774647887324, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=30.2752293577982, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787487, Length=142, Percent_Identity=30.9859154929577, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=35.7798165137615, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=147, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=109, Percent_Identity=35.7798165137615, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26257; Mature: 26126

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHHILLVEDDLSIQEMVEKYLVKEGFQVTIASDGEEGVNTYLKGSFDLIILDIMMPKLD
CCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCEEEEEECCCCCC
GLEVVRIIREKSAVPILMMSAKDTDVDKAVGLGLGADDYICKPFSMIELAARVKAGIRRS
CHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
TKYSATETTEKMIQIGDLTIDPINFTVEKNGKPLKLTLKEFEILKLFVKNQNRVFTKAQI
CCCCCHHHHHHHHHHCCEEECCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCEEEEEEE
YTLIWNEEYYGDDNVINVHMRRLREKIESDPSNPEYIKTLWGIGYKLEVM
EEEEECCCEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEC
>Mature Secondary Structure 
SHHILLVEDDLSIQEMVEKYLVKEGFQVTIASDGEEGVNTYLKGSFDLIILDIMMPKLD
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCEEEEEECCCCCC
GLEVVRIIREKSAVPILMMSAKDTDVDKAVGLGLGADDYICKPFSMIELAARVKAGIRRS
CHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
TKYSATETTEKMIQIGDLTIDPINFTVEKNGKPLKLTLKEFEILKLFVKNQNRVFTKAQI
CCCCCHHHHHHHHHHCCEEECCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCEEEEEEE
YTLIWNEEYYGDDNVINVHMRRLREKIESDPSNPEYIKTLWGIGYKLEVM
EEEEECCCEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]