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The map label for this gene is pncB

Identifier: 49481452

GI number: 49481452

Start: 4478385

End: 4479503

Strand: Reverse

Name: pncB

Synonym: BT9727_4421

Alternate gene names: NA

Gene position: 4479503-4478385 (Counterclockwise)

Preceding gene: 49481455

Following gene: 49481451

Centisome position: 85.52

GC content: 38.07

Gene sequence:

>1119_bases
ATGAAAGAAATTGAATTAAAATTAAAAGGTGAAATAAATAGACTAACAAATAAAACATTTAAATTTGACGAACGCGTTGG
AGAAGGTTGGTTCTCTGCCGTTTACTTTTTAAAGACTAGAGAAATCATCGAAGAATTTCGCCCGAAAAGTGTTGTAACGA
TGCAATTTTTCCAAAAGGAAAATGCAGTTCTTTGCGGAACAGATGAAGTCATTGCATTGCTACAAACATTCGCTAAAAAT
CCTGAGGAACTTGAGATTAACTCTTTAAAAGATGGCGATAAAATTAGTCCATTTGAAACAGTGTTAACAATTCATGGTCC
TTATGAAAATTTCGGATTTTTAGAAGGTGTTATTGATGGAATTTTAGCTCGTCGTACATCGGTTGCGACAAACGTATATA
ACGTTGTCCAAGCTGCGCGTAGCGTAGATAAAGAAAAACCAGTTATTTTCATGGGAGACCGTGATGATCATTATACACAA
CAAGCTGGTGACGGTTATGCAGCATACATCGGAGGTATGAGCGCACAAGCGACGCATGCGATGAATGAATGGTGGGGCAA
AAGTGGTATGGGGACAATGCCTCACGCATTAATTCAAATGTTTAATGGTGATGTTGTGGAAGCGGCAAAAGCATATCATA
AAAAATTCCCAGAAGATGAATTAGTTGTATTAATTGATTACAATAATGATGTCATTACAGATGCACTTCGCGTAGCACGT
GAATTTGGATCAACATTAAAAGGTGTACGTGTAGATACGTCTCGCACGATGATTGATCAATACTTCATTCGCCACCCAGA
AGTACTTGGAACATTCGATCCACGTGGTGTAAACCCATCGCTCGTATTCGCACTTCGTAAAGCACTTGATGAAGAAGGAT
TCCAGCATGTAGACATCGTTGTAACTGGTGGATTTGATGAGAAACGTATTCGTGAATTTGAAGCTCAAAACGTACCTGTT
GATATATACGGAGTAGGAAGTAGCTTATTAAAAATGAATATTGGCTTTACTGGTGATAACGTAGAATTAAATGGAAAACC
AGAGGCGAAAGCTGGTCGCAAATATCGTCCAAACCCACGTCTAGAGCGTGTTCAATTAGAAAAAAGAGAAGATATGTAA

Upstream 100 bases:

>100_bases
GAGGATGAATTTGCCGCTATGCAGGAAACAAATGTATAGTAAACGGTTTTGCTGTATACTAAGAGAAAATGTTGGATAGT
AAAGTAGGGAGTAAAGCGAC

Downstream 100 bases:

>100_bases
AAGAGAGAAAAACTGATAGGTGATTGACCCTATCAGTTTTTCTGTTATCATAGTATAGCGGCTTCTTTTTTGCTATAATG
GATTTGTTATGAACATAAAA

Product: nicotinate phosphoribosyltransferase

Products: nicotinate; 5-phospho-alpha-D-ribose 1-diphosphate

Alternate protein names: Quinolinate Phosphoribosyl Transferase; Nicotinic Acid Phosphoribosyltransferase; Nicotinic Acid Phosphoribosyltransferase-Like Protein; Nicotinate Phosphoribosyltransferase Family Protein; Nicotinate-Nucleotide Pyrophosphorylase

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKEIELKLKGEINRLTNKTFKFDERVGEGWFSAVYFLKTREIIEEFRPKSVVTMQFFQKENAVLCGTDEVIALLQTFAKN
PEELEINSLKDGDKISPFETVLTIHGPYENFGFLEGVIDGILARRTSVATNVYNVVQAARSVDKEKPVIFMGDRDDHYTQ
QAGDGYAAYIGGMSAQATHAMNEWWGKSGMGTMPHALIQMFNGDVVEAAKAYHKKFPEDELVVLIDYNNDVITDALRVAR
EFGSTLKGVRVDTSRTMIDQYFIRHPEVLGTFDPRGVNPSLVFALRKALDEEGFQHVDIVVTGGFDEKRIREFEAQNVPV
DIYGVGSSLLKMNIGFTGDNVELNGKPEAKAGRKYRPNPRLERVQLEKREDM

Sequences:

>Translated_372_residues
MKEIELKLKGEINRLTNKTFKFDERVGEGWFSAVYFLKTREIIEEFRPKSVVTMQFFQKENAVLCGTDEVIALLQTFAKN
PEELEINSLKDGDKISPFETVLTIHGPYENFGFLEGVIDGILARRTSVATNVYNVVQAARSVDKEKPVIFMGDRDDHYTQ
QAGDGYAAYIGGMSAQATHAMNEWWGKSGMGTMPHALIQMFNGDVVEAAKAYHKKFPEDELVVLIDYNNDVITDALRVAR
EFGSTLKGVRVDTSRTMIDQYFIRHPEVLGTFDPRGVNPSLVFALRKALDEEGFQHVDIVVTGGFDEKRIREFEAQNVPV
DIYGVGSSLLKMNIGFTGDNVELNGKPEAKAGRKYRPNPRLERVQLEKREDM
>Mature_372_residues
MKEIELKLKGEINRLTNKTFKFDERVGEGWFSAVYFLKTREIIEEFRPKSVVTMQFFQKENAVLCGTDEVIALLQTFAKN
PEELEINSLKDGDKISPFETVLTIHGPYENFGFLEGVIDGILARRTSVATNVYNVVQAARSVDKEKPVIFMGDRDDHYTQ
QAGDGYAAYIGGMSAQATHAMNEWWGKSGMGTMPHALIQMFNGDVVEAAKAYHKKFPEDELVVLIDYNNDVITDALRVAR
EFGSTLKGVRVDTSRTMIDQYFIRHPEVLGTFDPRGVNPSLVFALRKALDEEGFQHVDIVVTGGFDEKRIREFEAQNVPV
DIYGVGSSLLKMNIGFTGDNVELNGKPEAKAGRKYRPNPRLERVQLEKREDM

Specific function: Unknown

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.11

Molecular weight: Translated: 42020; Mature: 42020

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIELKLKGEINRLTNKTFKFDERVGEGWFSAVYFLKTREIIEEFRPKSVVTMQFFQKE
CCCEEEEECCHHHHHHCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCC
NAVLCGTDEVIALLQTFAKNPEELEINSLKDGDKISPFETVLTIHGPYENFGFLEGVIDG
CCEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
ILARRTSVATNVYNVVQAARSVDKEKPVIFMGDRDDHYTQQAGDGYAAYIGGMSAQATHA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHCCCCEEEEECCCCHHHHHH
MNEWWGKSGMGTMPHALIQMFNGDVVEAAKAYHKKFPEDELVVLIDYNNDVITDALRVAR
HHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
EFGSTLKGVRVDTSRTMIDQYFIRHPEVLGTFDPRGVNPSLVFALRKALDEEGFQHVDIV
HHHHHHCCEEECHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
VTGGFDEKRIREFEAQNVPVDIYGVGSSLLKMNIGFTGDNVELNGKPEAKAGRKYRPNPR
EECCCCHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCC
LERVQLEKREDM
HHHHHHHHHCCC
>Mature Secondary Structure
MKEIELKLKGEINRLTNKTFKFDERVGEGWFSAVYFLKTREIIEEFRPKSVVTMQFFQKE
CCCEEEEECCHHHHHHCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCC
NAVLCGTDEVIALLQTFAKNPEELEINSLKDGDKISPFETVLTIHGPYENFGFLEGVIDG
CCEEECCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
ILARRTSVATNVYNVVQAARSVDKEKPVIFMGDRDDHYTQQAGDGYAAYIGGMSAQATHA
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHCCCCEEEEECCCCHHHHHH
MNEWWGKSGMGTMPHALIQMFNGDVVEAAKAYHKKFPEDELVVLIDYNNDVITDALRVAR
HHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
EFGSTLKGVRVDTSRTMIDQYFIRHPEVLGTFDPRGVNPSLVFALRKALDEEGFQHVDIV
HHHHHHCCEEECHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
VTGGFDEKRIREFEAQNVPVDIYGVGSSLLKMNIGFTGDNVELNGKPEAKAGRKYRPNPR
EECCCCHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCCC
LERVQLEKREDM
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinate D-ribonucleotide; diphosphate

Specific reaction: nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA