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The map label for this gene is ccpA

Identifier: 49481438

GI number: 49481438

Start: 4469049

End: 4470047

Strand: Reverse

Name: ccpA

Synonym: BT9727_4410

Alternate gene names: 49481438

Gene position: 4470047-4469049 (Counterclockwise)

Preceding gene: 49480708

Following gene: 49480706

Centisome position: 85.34

GC content: 38.74

Gene sequence:

>999_bases
ATGAACGTAACAATATATGATGTAGCGCGCGAAGCGAACGTTTCAATGGCTACCGTATCACGCGTTGTGAACGGTAACCC
AAATGTAAAGCCTACAACAAGAAAGAAAGTATTAGAAGCAATTGATCGTTTAGGATACCGCCCAAATGCGGTAGCACGTG
GATTAGCAAGTAAGAAGACAACTACAGTAGGTGTTATTATTCCTGATATCTCAAATACGTTTTATGCAGAACTTGCTCGT
GGAATTGAAGATATCGCAACAATGTACAAATATAACATCATTTTAAGTAACTCTGACCAAAACAAAGAGAAAGAGTTCCA
TTTATTAAATACGATGCTTGGAAAACAAGTGGACGGAATTGTTTTCATGGGTGAAGATATTACAGACATTCACATTGAAG
AATTTAAAAAGTCTCCAGTACCAATCGTATTAGCAGCGTCATTTGATGAGCAAAATGAAACGCCATCAGTAAACATTGAT
TATACACAAGCAGCTTACGACGCAATGAAGCACTTTATTGAACAAGGACATAAGCGTATCGGTTTCGTCTCTGGTCCTTT
CATTGATAAAGCGGGAAGCGCGAAGAAATTACAAGGTTATAAAAATGCTCTAGAAGAAGCAGGTATTTCATATGATGAAA
ATCTTGTAATCGATGGAGATTACACATATGACTCAGGTATCGAAGCATTCGAAAAGCTTTGGAGCCTTGATGAGAAGCCG
TCAGCAATCTTCGTATCTTCTGACGAAATGGCACTAGGTGTAATCCACGCAGCACAAGACGCTGGATTAAACGTACCAAC
TGATGTAGAAGTACTTGGATTCGATAATACACGCCTTGCATTAATGGTTCGTCCGCAACTTTCAACAGTTGTACAACCGA
TGTATGATATCGGTGCAGTAGCAATGCGTCTGTTAACAAAGTATATGAACAAAGAAAAAGTGGAAGATCACACTGTTATC
TTACCTCACCGTATCCAATTTAGAGATTCAACGAAGTAA

Upstream 100 bases:

>100_bases
GACGATTGGTGGCATCTGCAAATAGAGTTGATGTCTTTTTTTCATTCAAGTAACCGATACATAAAAATAGATAGCAAAAA
TAGAAGGAGTGTGCGATGAG

Downstream 100 bases:

>100_bases
GTATAAAAAAGCTCACAGCGATTGCTGTGAGCTTTTATTTATATTCAGGATAGTATGTTTGAACTATAGTATCCACCGTT
TCATTTTTCTTAACGTGTAA

Product: catabolite control protein A

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYAELAR
GIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHIEEFKKSPVPIVLAASFDEQNETPSVNID
YTQAAYDAMKHFIEQGHKRIGFVSGPFIDKAGSAKKLQGYKNALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSLDEKP
SAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVEDHTVI
LPHRIQFRDSTK

Sequences:

>Translated_332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYAELAR
GIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHIEEFKKSPVPIVLAASFDEQNETPSVNID
YTQAAYDAMKHFIEQGHKRIGFVSGPFIDKAGSAKKLQGYKNALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSLDEKP
SAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVEDHTVI
LPHRIQFRDSTK
>Mature_332_residues
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYAELAR
GIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHIEEFKKSPVPIVLAASFDEQNETPSVNID
YTQAAYDAMKHFIEQGHKRIGFVSGPFIDKAGSAKKLQGYKNALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSLDEKP
SAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVEDHTVI
LPHRIQFRDSTK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=36.969696969697, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=34.0425531914894, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790194, Length=321, Percent_Identity=32.398753894081, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=32.8990228013029, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789202, Length=291, Percent_Identity=32.3024054982818, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1788474, Length=302, Percent_Identity=30.1324503311258, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1787580, Length=329, Percent_Identity=27.0516717325228, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI48994940, Length=304, Percent_Identity=27.3026315789474, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1786540, Length=333, Percent_Identity=27.3273273273273, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=23.0283911671924, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787906, Length=261, Percent_Identity=26.4367816091954, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789456, Length=354, Percent_Identity=27.683615819209, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786268, Length=314, Percent_Identity=24.8407643312102, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=22.4924012158055, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36901; Mature: 36901

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKT
CCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCC
TTVGVIIPDISNTFYAELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGI
EEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
VFMGEDITDIHIEEFKKSPVPIVLAASFDEQNETPSVNIDYTQAAYDAMKHFIEQGHKRI
EEECCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHCHHEE
GFVSGPFIDKAGSAKKLQGYKNALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSLDEKP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCC
SAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAV
CEEEEECCCEEEEEEEEHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
AMRLLTKYMNKEKVEDHTVILPHRIQFRDSTK
HHHHHHHHHCHHCCCCCEEEECCEEECCCCCC
>Mature Secondary Structure
MNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKT
CCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCC
TTVGVIIPDISNTFYAELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGI
EEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCE
VFMGEDITDIHIEEFKKSPVPIVLAASFDEQNETPSVNIDYTQAAYDAMKHFIEQGHKRI
EEECCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHCHHEE
GFVSGPFIDKAGSAKKLQGYKNALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSLDEKP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCC
SAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAV
CEEEEECCCEEEEEEEEHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
AMRLLTKYMNKEKVEDHTVILPHRIQFRDSTK
HHHHHHHHHCHHCCCCCEEEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]