Click here to switch to the map view.

The map label for this gene is murA

Identifier: 49481255

GI number: 49481255

Start: 5024143

End: 5025447

Strand: Reverse

Name: murA

Synonym: BT9727_4969

Alternate gene names: 49481255

Gene position: 5025447-5024143 (Counterclockwise)

Preceding gene: 49478954

Following gene: 49479332

Centisome position: 95.95

GC content: 40.23

Gene sequence:

>1305_bases
TTGGAAAAGATCATCGTCCGTGGCGGAAAGCGGTTAAACGGCACAGTGCGTGTTGAGGGCGCAAAAAATGCTGTATTACC
TATAATCGCTGCAGCCCTATTAGCGAGTGATGGAAAGAATGTACTATCTGAAGTACCAGTTTTGTCTGATGTATACACAA
TTAATGAGGTATTACGTCATTTAAATGCTGAAGTCGTATTTGAAAATAACCAAGTAACAATCGATGCTTCTAAAGAGCTA
AACATTGAAGCACCATTTGAATATGTACGTAAAATGCGTGCATCTGTTCAAGTAATGGGACCATTATTAGCACGTAATGG
TCGTGCTCGTATTGCACTTCCTGGTGGATGTGCAATTGGTTCACGTCCAATTGACCAACATTTAAAAGGCTTCGAAGCAA
TGGGAGCAAAAGTACAGGTTGGTAACGGTTTTGTTGAGGCATACGTTGAGGGAGAACTAAAAGGAGCTAAAATTTATTTA
GACTTCCCAAGCGTGGGCGCAACAGAAAATATTATGTCTGCAGCTACATTAGCAAAAGGGACAACAATCCTTGAAAACGC
AGCGAAAGAACCAGAAATCGTTGACTTAGCTAACTTCTTAAATGCGATGGGAGCGAAAGTACGCGGAGCTGGAACTGGAA
CGATTCGTATCGAAGGCGTTGATAAATTATATGGTGCAAACCACTCTATTATTCCTGACCGTATTGAAGCGGGAACATTC
ATGGTTGCAGCGGCAATTACTGGTGGAGACATCTTAATTGAAAATGCTGTACCTGAACATTTACGCTCAATTACAGCGAA
AATGGAAGAAATGGGTGTTAAAATTATCGAAGAAAATGAAGGTGTACGTGTTATCGGCCCAGATAAGTTAAAAGCGGTTG
ATATTAAAACTATGCCTCACCCAGGTTTCCCAACAGACATGCAATCACAAATGATGGCATTATTACTACAAGCTGATGGC
ACAAGTATGATTACAGAAACGGTATTTGAAAACCGCTTTATGCACGTTGAAGAATTCCGTCGTATGAATGCTGATATTAA
AATCGAAGGTCGTTCTGTTATTATGAACGGTCCAAACAGCTTACAAGGTGCTGAAGTAAGCGCAACTGATTTACGTGCTG
CTGCTGCATTAATCTTAGCTGGTTTAGTATCAGAAGGTTACACTCGTGTAACTGAGTTAAAGCATCTTGACCGTGGTTAT
GTAGATTTCCATAAGAAATTAGCTGCATTAGGTGCAACTATTGAACGTGTAAACGAAAAAGTAGAAGAAGTGAAAGAACA
AGAAGTTTCTGATCTTCACGCTTAA

Upstream 100 bases:

>100_bases
TTCTACAGACAACAAAGATACAATTGTGGTTGGCACACCGATCATAACTTCTGAGTATTGAGTGAATAGATACTGAAAAA
AGGACACGGAGGGGAATAAT

Downstream 100 bases:

>100_bases
TTGAAATAGTCTCTACGTCTTTTGACGTAGAGGCTATTTTTTTGGGTTATTACTGTTATAGTCAAGAAATTCTATACTTA
TGCACGTACCAGTAAAAATA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVSATDLRAAAALILAGLVSEGYTRVTELKHLDRGY
VDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA

Sequences:

>Translated_434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVSATDLRAAAALILAGLVSEGYTRVTELKHLDRGY
VDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>Mature_434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVSATDLRAAAALILAGLVSEGYTRVTELKHLDRGY
VDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=51.6666666666667, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46804; Mature: 46804

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRH
CCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHH
LNAEVVFENNQVTIDASKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIG
CCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKG
CCCHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCC
TTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
CHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCHHHHCCCCCCCCCCCCCCEE
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPH
EEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCEEEEEEEECCC
PGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEECCCCC
LQGAEVSATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEK
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VEEVKEQEVSDLHA
HHHHHHHHHHHCCC
>Mature Secondary Structure
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRH
CCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHH
LNAEVVFENNQVTIDASKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIG
CCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKG
CCCHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCC
TTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
CHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCHHHHCCCCCCCCCCCCCCEE
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPH
EEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCEEEEEEEECCC
PGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEECCCCC
LQGAEVSATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEK
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VEEVKEQEVSDLHA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]