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The map label for this gene is yyxA [H]

Identifier: 49481211

GI number: 49481211

Start: 5209953

End: 5211128

Strand: Reverse

Name: yyxA [H]

Synonym: BT9727_5142

Alternate gene names: 49481211

Gene position: 5211128-5209953 (Counterclockwise)

Preceding gene: 49479014

Following gene: 49480815

Centisome position: 99.49

GC content: 38.27

Gene sequence:

>1176_bases
ATGTCCTTTATTGATGGAGAAAATTATCGTATGAAACGTGCAAGGAAAAAGAAGCATAAAGGTATTGTTATTTCTAGCAT
AGCAGGAACAATTGTAGGAGCTTCGTTATTTGCATTTGGAGCTCCTTTATTTTCAAATGATACGGACGCGTTTCCGCAAG
CTGAAGCAAGTGGAAGTAATATGGCCGAAGCTCAAGGAATTAAACAGATTAGCTTTGTGGATGCTGTTGATCGTGCATCT
GAAGCTGTTGTTGGTATTATTAATATTCAACGAGATAATTTTTCAGAGGCAGATTCAGAAGCTGGCACAGGCTCAGGTGT
AATTTATAAGAAGACAGATGGTCAAGCTTATATTGTAACGAATAATCATGTTGTTGCTGGGGCAAATCGTATTGAAGTAA
GTTTAAGTGACGGTAAGAAGGTTCCAGGAAAGGTATTAGGAACCGATGTAGTCACAGATTTGGCTGTACTAGAGATAGAT
GCAAAGTATGTGAAAAAGGTAATTGAGATTGGCGATTCTAATGCTGTTCGTAGAGGAGAACCAGTCATTGCGATTGGGAA
CCCGCTCGGGTTACAATTTTCTGGAACCGTCACACAAGGTATTATTTCGGCTAATGAGCGTATTGTTCCTGTAGATTTAG
ATCAAGATGGACATTATGATTGGCAAGTAGAAGTATTGCAAACAGACGCAGCAATTAATCCGGGTAATAGTGGTGGTGCG
CTTGTAAATGCAGCAGGTCAATTAATTGGTATTAACTCAATGAAAATTGCTGCAAAAGAAGTAGAAGGAATTGGTCTAGC
TATTCCAGTGACTAGAGCTGTTCCAATTATGAATGAATTAGAGAAGTACGGAAAAGTAAGAAGACCGTATGTTGGAATTG
AACTGAGATCATTAAATGAGATTCCAAACTACTATTGGTCAAAAACATTGCATTTACCAGGCAATATAACAGAGGGAGTT
TGCATTTTAGATGTGAAAAGTCCTTCGCCAGGCACAGATGCTGGTTTACGAGAACACGATGTAATTGTAGCAGTAGATGG
AAAACCGGTTCGTGATATTATCGGATTCCGTACGGCCTTATATGATAAAAAAATTAATGATAAAATGACTCTTACGTTTT
ATCGTGGTACAAAACGAGCAACAACAACGGTTAAACTAGGCATTCAAAAGTATTAA

Upstream 100 bases:

>100_bases
AGATCCAAAAATGCCTACAAAAATTCAATACGTATAATTCTCCATTTTAGTAAACAATAAAGGTGAATATAGTTGTTTTC
AGGAAGATAGGTGAACAAAT

Downstream 100 bases:

>100_bases
AAACAGGAGGGCCTACCTCCTGTTTTCTATTGTAGAAAAGTGAGGTGAAGAATATGAATTTACCTTGTTGTTTACAACAT
GTTGAATTAGCGTTAGATAT

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDTDAFPQAEASGSNMAEAQGIKQISFVDAVDRAS
EAVVGIINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEID
AKYVKKVIEIGDSNAVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNITEGV
CILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY

Sequences:

>Translated_391_residues
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDTDAFPQAEASGSNMAEAQGIKQISFVDAVDRAS
EAVVGIINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEID
AKYVKKVIEIGDSNAVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNITEGV
CILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY
>Mature_390_residues
SFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDTDAFPQAEASGSNMAEAQGIKQISFVDAVDRASE
AVVGIINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDA
KYVKKVIEIGDSNAVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGAL
VNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNITEGVC
ILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=284, Percent_Identity=34.5070422535211, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI24308541, Length=289, Percent_Identity=34.6020761245675, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI22129776, Length=288, Percent_Identity=31.9444444444444, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI7019477, Length=322, Percent_Identity=36.0248447204969, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI1789630, Length=378, Percent_Identity=35.7142857142857, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786356, Length=284, Percent_Identity=37.3239436619718, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789629, Length=286, Percent_Identity=34.2657342657343, Blast_Score=142, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24646839, Length=306, Percent_Identity=34.640522875817, Blast_Score=134, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41928; Mature: 41797

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDTDAFPQAEASGSN
CCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MAEAQGIKQISFVDAVDRASEAVVGIINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVT
CHHHHCCCEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEE
NNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDAKYVKKVIEIGDSNAVRRGE
CCEEEECCCEEEEEECCCCCCCCHHCCHHHHHHEEEEEECHHHHHHHHHCCCCCCCCCCC
PVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
CEEEECCCCCEEECCCHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCE
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNE
EEECCCCEEECCCCEEEHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCHHH
IPNYYWSKTLHLPGNITEGVCILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTAL
CCCCHHCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
YDKKINDKMTLTFYRGTKRATTTVKLGIQKY
HCCCCCCCEEEEEEECCCCEEEEEEEEEECC
>Mature Secondary Structure 
SFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDTDAFPQAEASGSN
CCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MAEAQGIKQISFVDAVDRASEAVVGIINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVT
CHHHHCCCEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEE
NNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDAKYVKKVIEIGDSNAVRRGE
CCEEEECCCEEEEEECCCCCCCCHHCCHHHHHHEEEEEECHHHHHHHHHCCCCCCCCCCC
PVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
CEEEECCCCCEEECCCHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCE
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNE
EEECCCCEEECCCCEEEHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCHHH
IPNYYWSKTLHLPGNITEGVCILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTAL
CCCCHHCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
YDKKINDKMTLTFYRGTKRATTTVKLGIQKY
HCCCCCCCEEEEEEECCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]