Click here to switch to the map view.

The map label for this gene is sigW [H]

Identifier: 49480428

GI number: 49480428

Start: 5107205

End: 5107735

Strand: Reverse

Name: sigW [H]

Synonym: BT9727_5044

Alternate gene names: 49480428

Gene position: 5107735-5107205 (Counterclockwise)

Preceding gene: 49481250

Following gene: 49480805

Centisome position: 97.52

GC content: 32.39

Gene sequence:

>531_bases
ATGATGGAAGAAAAGGTAGAAGAACTAATTGATATATATAAGCGGCAAATATATTCCTTATGCTATAAATTAGCGAAGAC
GAAAGAAGACGCGGAAGATATTTTTCAAGAGACGTGGATAAAAGTTTTTTCATCGCGGCACCAACTTTCTTACGTGGAGA
ATTATAAAAAGTGGATTACTACGATTTGTGTTCGTACATTTTATGATTTTTATCGCAAAAAGAAAAGGTGGAAAGATCGT
GTATTGGATTTATTTCATAAAGAAGATGGTGGAGAAATAGAGCTTGCAGATGATGTGAATATATCAGAAGAATTCATTCA
AAAAGTCGAAGCAGAAATGATACGAGAAGTTATACAGTTATTAAACGAAAAATATAAAACAGTGCTCGTACTCTACTATT
ATGAACAATATTCTTACAAAGAAATGAGTGAAATATTAAATATACCAATTGGTACGGTGAAATACCGTCTTAATTATGCC
AAGAAGCAAATGCGAGAATATTTGGAGGGGTTCGTTCATGAAGGAAGATAA

Upstream 100 bases:

>100_bases
ACAATGTTGTGATTGCCTTTTTATATGGAAATAATAAAAAATAAAATTTTATCAAACAAAAGAGGAATTTGCGTCGTCTT
ATATAAATGACAGGAGGTTT

Downstream 100 bases:

>100_bases
ATTTGAACAGAAGATAAAGAGTAGCTTAGCAGAAGAGATAATTCCAAGCGAAGAGCTAATAAATAATACGAAGCAAGGCG
TACGAAAGGCTCAGAAACTA

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MMEEKVEELIDIYKRQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITTICVRTFYDFYRKKKRWKDR
VLDLFHKEDGGEIELADDVNISEEFIQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYA
KKQMREYLEGFVHEGR

Sequences:

>Translated_176_residues
MMEEKVEELIDIYKRQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITTICVRTFYDFYRKKKRWKDR
VLDLFHKEDGGEIELADDVNISEEFIQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYA
KKQMREYLEGFVHEGR
>Mature_176_residues
MMEEKVEELIDIYKRQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITTICVRTFYDFYRKKKRWKDR
VLDLFHKEDGGEIELADDVNISEEFIQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYA
KKQMREYLEGFVHEGR

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21616; Mature: 21616

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEEKVEELIDIYKRQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWIT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TICVRTFYDFYRKKKRWKDRVLDLFHKEDGGEIELADDVNISEEFIQKVEAEMIREVIQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHH
LNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKKQMREYLEGFVHEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMEEKVEELIDIYKRQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWIT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TICVRTFYDFYRKKKRWKDRVLDLFHKEDGGEIELADDVNISEEFIQKVEAEMIREVIQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHH
LNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKKQMREYLEGFVHEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]