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The map label for this gene is deoD

Identifier: 49480323

GI number: 49480323

Start: 3916119

End: 3916940

Strand: Reverse

Name: deoD

Synonym: BT9727_3827

Alternate gene names: 49480323

Gene position: 3916940-3916119 (Counterclockwise)

Preceding gene: 49480324

Following gene: 49480320

Centisome position: 74.78

GC content: 38.93

Gene sequence:

>822_bases
ATGAATCGTGAACTTATTACAAAATCAGCTTCATACTTAAAAGAGAAATTTCAAGAGACACCACAAGTAGGACTAATCCT
TGGATCTGGACTAGGTGTATTAGCAGATGAAATCGAGAACGCAGTAACAGTACCTTACAGTGAAATCCCTGAATTCCCAG
TATCAACTGTAGAAGGTCATGCAGGCCAACTAGTATTCGGTACACTTCAAGGTGTAACAGTAGTAGCAATGCAAGGACGT
TTCCACTTCTATGAAGGATACGATATGCAAAAAGTAACATTCCCAGTTCGTGTTATGAAAGAACTAGGTGTAGAAACAGT
TGTTGTAACAAATGCAGCTGGTGGTGTAAATACATCATTCGAACCAGGCGATCTTATGTTAATTTCAGATCACATTAACT
TCATGGGTACAAATCCATTAATCGGACCAAATGATTCTGAAATGGGTGTACGTTTCCCTGATATGTCTACATCATATACA
GTAGAACTACGCGAAATGGCGAAACAAGTTGCAGCAAACTTAAATATTAAAGTACAAGAAGGGGTATACGTTGGAATGAC
AGGTCCTGTATATGAAACACCTGCAGAAATTCGTATGCTTCGTACACTTGGCGGAGATGCAGTTGGTATGTCAACAGTAC
CTGAAGTAATTGTAGCGCGTCACGCTGGTATGAAAGTACTTGGTATTTCTTGTATTTCAAATATGGCAGCTGGTATTTTA
GATCAGCCACTTCACCACGATGAAGTAATCGAAACGACAGAACGTGTTAAAGCTAATTTCTTAGCATTAGTAAAAGCAAT
CGTAAAACAAATGAAGGGGTGA

Upstream 100 bases:

>100_bases
TGCTGATATTGGTGCAACTGTAGCAGAAAACTTCGGTGTGAAAATGCCAGAATACGGAACAAGCTTCTTAAACGAGCTAA
AGAAATAGGGGGATAAACAA

Downstream 100 bases:

>100_bases
CCTCACAATGAGAATGGTGGACCTAATTGCAAAAAAACGTGACGGACATGCATTAACGACAGAAGAAATTGACTTTATTG
TTGAAGGATATACAAATGGT

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: Inosine phosphorylase; Purine nucleoside phosphorylase I; PNP I; PU-NPase I [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MNRELITKSASYLKEKFQETPQVGLILGSGLGVLADEIENAVTVPYSEIPEFPVSTVEGHAGQLVFGTLQGVTVVAMQGR
FHFYEGYDMQKVTFPVRVMKELGVETVVVTNAAGGVNTSFEPGDLMLISDHINFMGTNPLIGPNDSEMGVRFPDMSTSYT
VELREMAKQVAANLNIKVQEGVYVGMTGPVYETPAEIRMLRTLGGDAVGMSTVPEVIVARHAGMKVLGISCISNMAAGIL
DQPLHHDEVIETTERVKANFLALVKAIVKQMKG

Sequences:

>Translated_273_residues
MNRELITKSASYLKEKFQETPQVGLILGSGLGVLADEIENAVTVPYSEIPEFPVSTVEGHAGQLVFGTLQGVTVVAMQGR
FHFYEGYDMQKVTFPVRVMKELGVETVVVTNAAGGVNTSFEPGDLMLISDHINFMGTNPLIGPNDSEMGVRFPDMSTSYT
VELREMAKQVAANLNIKVQEGVYVGMTGPVYETPAEIRMLRTLGGDAVGMSTVPEVIVARHAGMKVLGISCISNMAAGIL
DQPLHHDEVIETTERVKANFLALVKAIVKQMKG
>Mature_273_residues
MNRELITKSASYLKEKFQETPQVGLILGSGLGVLADEIENAVTVPYSEIPEFPVSTVEGHAGQLVFGTLQGVTVVAMQGR
FHFYEGYDMQKVTFPVRVMKELGVETVVVTNAAGGVNTSFEPGDLMLISDHINFMGTNPLIGPNDSEMGVRFPDMSTSYT
VELREMAKQVAANLNIKVQEGVYVGMTGPVYETPAEIRMLRTLGGDAVGMSTVPEVIVARHAGMKVLGISCISNMAAGIL
DQPLHHDEVIETTERVKANFLALVKAIVKQMKG

Specific function: Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI157168362, Length=256, Percent_Identity=53.515625, Blast_Score=258, Evalue=4e-69,
Organism=Homo sapiens, GI47132622, Length=247, Percent_Identity=27.9352226720648, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1788746, Length=252, Percent_Identity=48.4126984126984, Blast_Score=246, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17541190, Length=279, Percent_Identity=41.5770609318996, Blast_Score=220, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6323238, Length=301, Percent_Identity=43.1893687707641, Blast_Score=220, Evalue=2e-58,
Organism=Drosophila melanogaster, GI45552885, Length=277, Percent_Identity=48.014440433213, Blast_Score=253, Evalue=8e-68,
Organism=Drosophila melanogaster, GI45552887, Length=277, Percent_Identity=48.014440433213, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24656093, Length=277, Percent_Identity=48.014440433213, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24656090, Length=277, Percent_Identity=48.014440433213, Blast_Score=252, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24762376, Length=239, Percent_Identity=39.3305439330544, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI221459247, Length=220, Percent_Identity=25.4545454545455, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130079, Length=213, Percent_Identity=27.6995305164319, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011268
- InterPro:   IPR000845
- InterPro:   IPR011270
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 29534; Mature: 29534

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01240 PNP_MTAP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRELITKSASYLKEKFQETPQVGLILGSGLGVLADEIENAVTVPYSEIPEFPVSTVEGH
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCEECCHHHCCCCCCCCCCCC
AGQLVFGTLQGVTVVAMQGRFHFYEGYDMQKVTFPVRVMKELGVETVVVTNAAGGVNTSF
CCEEEEEECCCEEEEEEECCEEEECCCCCEEEHHHHHHHHHCCCEEEEEEECCCCCCCCC
EPGDLMLISDHINFMGTNPLIGPNDSEMGVRFPDMSTSYTVELREMAKQVAANLNIKVQE
CCCCEEEEECCCCEEECCCCCCCCCCCCCEECCCCCCCEEHHHHHHHHHHHHCCCEEEEC
GVYVGMTGPVYETPAEIRMLRTLGGDAVGMSTVPEVIVARHAGMKVLGISCISNMAAGIL
CEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
DQPLHHDEVIETTERVKANFLALVKAIVKQMKG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRELITKSASYLKEKFQETPQVGLILGSGLGVLADEIENAVTVPYSEIPEFPVSTVEGH
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCEECCHHHCCCCCCCCCCCC
AGQLVFGTLQGVTVVAMQGRFHFYEGYDMQKVTFPVRVMKELGVETVVVTNAAGGVNTSF
CCEEEEEECCCEEEEEEECCEEEECCCCCEEEHHHHHHHHHCCCEEEEEEECCCCCCCCC
EPGDLMLISDHINFMGTNPLIGPNDSEMGVRFPDMSTSYTVELREMAKQVAANLNIKVQE
CCCCEEEEECCCCEEECCCCCCCCCCCCCEECCCCCCCEEHHHHHHHHHHHHCCCEEEEC
GVYVGMTGPVYETPAEIRMLRTLGGDAVGMSTVPEVIVARHAGMKVLGISCISNMAAGIL
CEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHH
DQPLHHDEVIETTERVKANFLALVKAIVKQMKG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9058965 [H]