Click here to switch to the map view.

The map label for this gene is gtaB

Identifier: 49478945

GI number: 49478945

Start: 5011216

End: 5012109

Strand: Reverse

Name: gtaB

Synonym: BT9727_4956

Alternate gene names: 49478945

Gene position: 5012109-5011216 (Counterclockwise)

Preceding gene: 49478946

Following gene: 49478944

Centisome position: 95.69

GC content: 35.35

Gene sequence:

>894_bases
TTGAAAAAAGTGAGAAAAGCAATTATACCAGCAGCTGGTCTTGGGACGAGATTTTTACCAGCAACGAAAGCGATGCCGAA
AGAAATGTTACCTATCGTCGATAAACCAACAATTCAATACATAATAGAGGAAGCGATAGAATCAGGAATTGAAGATATTA
TTATTGTTACTGGAAAAGGAAAGCGTGCTATTGAAGATCATTTCGATCATTCTTTTGAACTAGAACAAAACCTTTTAGAA
AAAGGAAAGTATGAAATGCTTGAGAAAGTACAAGCATCTTCAAAGATTAACATTCATTACATAAGACAGAAAGAACCAAA
AGGTCTAGGGCATGCAGTATGGTGTGCACGTAAATTTATTGGAAATGAACCATTTGCGGTATTACTTGGTGATGATATTG
TACAAGCAGAAACGCCATGTTTACGTCAATTGATGGATCAATATGAAGGTACACAATCGTCAGTTATTGGTGTACAAACA
GTACCTGAAAATGAAACACATCGTTACGGTATTATCGATCCAGTTGAACAAAATGAACGTCGTTATCAAGTGCGTCAATT
TGTTGAAAAGCCAGCAGAAGGTACAGCACCATCTAATTTAGCGATTATGGGTCGTTACGTATTAACACCAGAAATCTTTA
TGTTCCTTGAGGATCAGCAAACAGGTGCTGGTGGAGAGATTCAATTAACAGATGCAATTCAACGTTTAAATGAAATTCAA
CGTGTATTTGCTTATGATTTTGAAGGTATTCGTTACGATGTTGGGGAGAAGTTTGGATTTATTAAGACGACAATTGAGAT
GGCATTACAACATGAAGAATTAAGAGAGTCATTAATAAATTATATGGCTGGAATTTTGAAGAAGAAAAATAAGTATGAAG
GTGAGGTGAAATAA

Upstream 100 bases:

>100_bases
ATTTCTAATAGAAACTCTACCTATGGAGTTATAAACATGACTCTATAGGTAGGGTTTTTGTTATTGTTACATATAAATAG
TTAAATGCGGAGGGTTACAA

Downstream 100 bases:

>100_bases
TTTTGAGTTTAGTAAAAATATCAGAGGATAAATTAACAAAGGGAGAAAATGAAGTTCTAGTTTGTGAGCAAGTACCTGTC
CGTAAAGGGTATATATTGGC

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQNLLE
KGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQT
VPENETHRYGIIDPVEQNERRYQVRQFVEKPAEGTAPSNLAIMGRYVLTPEIFMFLEDQQTGAGGEIQLTDAIQRLNEIQ
RVFAYDFEGIRYDVGEKFGFIKTTIEMALQHEELRESLINYMAGILKKKNKYEGEVK

Sequences:

>Translated_297_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQNLLE
KGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQT
VPENETHRYGIIDPVEQNERRYQVRQFVEKPAEGTAPSNLAIMGRYVLTPEIFMFLEDQQTGAGGEIQLTDAIQRLNEIQ
RVFAYDFEGIRYDVGEKFGFIKTTIEMALQHEELRESLINYMAGILKKKNKYEGEVK
>Mature_297_residues
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQNLLE
KGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQT
VPENETHRYGIIDPVEQNERRYQVRQFVEKPAEGTAPSNLAIMGRYVLTPEIFMFLEDQQTGAGGEIQLTDAIQRLNEIQ
RVFAYDFEGIRYDVGEKFGFIKTTIEMALQHEELRESLINYMAGILKKKNKYEGEVK

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=282, Percent_Identity=45.3900709219858, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI1788355, Length=277, Percent_Identity=41.1552346570397, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1788351, Length=229, Percent_Identity=30.5676855895196, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790224, Length=268, Percent_Identity=28.3582089552239, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320148, Length=264, Percent_Identity=26.5151515151515, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 33806; Mature: 33806

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKG
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDHSFELEQNLLEKGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFI
CHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
GNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPENETHRYGIIDPVEQNER
CCCCEEEEECCCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHH
RYQVRQFVEKPAEGTAPSNLAIMGRYVLTPEIFMFLEDQQTGAGGEIQLTDAIQRLNEIQ
HHHHHHHHHCCCCCCCCCCCEEEEHHHCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHH
RVFAYDFEGIRYDVGEKFGFIKTTIEMALQHEELRESLINYMAGILKKKNKYEGEVK
HHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKG
CCHHHHHHCCCCCCCCCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
KRAIEDHFDHSFELEQNLLEKGKYEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFI
CHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
GNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPENETHRYGIIDPVEQNER
CCCCEEEEECCCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHH
RYQVRQFVEKPAEGTAPSNLAIMGRYVLTPEIFMFLEDQQTGAGGEIQLTDAIQRLNEIQ
HHHHHHHHHCCCCCCCCCCCEEEEHHHCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHHH
RVFAYDFEGIRYDVGEKFGFIKTTIEMALQHEELRESLINYMAGILKKKNKYEGEVK
HHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]